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2. Indomethacin with or without prophylactic pancreatic stent placement to prevent pancreatitis after ERCP: a randomised non-inferiority trial

Author

Elmunzer, B. Joseph, Foster, Lydia D., Serrano, Jose, Coté, Gregory A., Edmundowicz, Steven A., Wani, Sachin, Shah, Raj, Bang, Ji Young, Varadarajulu, Shyam, Singh, Vikesh K., Khashab, Mouen, Kwon, Richard S., Scheiman, James M., Willingham, Field F., Keilin, Steven A., Papachristou, Georgios I., Chak, Amitabh, Slivka, Adam, Mullady, Daniel, Kushnir, Vladimir, Buxbaum, James, Keswani, Rajesh, Gardner, Timothy B., Forbes, Nauzer, Rastogi, Amit, Ross, Andrew, Law, Joanna, Yachimski, Patrick, Chen, Yen-I, Barkun, Alan, Smith, Zachary L., Petersen, Bret, Wang, Andrew Y., Saltzman, John R., Spitzer, Rebecca L., Ordiah, Collins, Spino, Cathie, Higgins, Peter D.R., Forster, Erin, Moran, Robert A., Brauer, Brian, Wamsteker, Erik J., Cai, Qiang, Qayed, Emad, Groce, Royce, Krishna, Somashekar G., Faulx, Ashley, Glessing, Brooke, Rabinovitz, Mordechai, Lang, Gabriel, Aadam, Aziz, Komanduri, Srinadh, Adler, Jefferey, Gordon, Stuart, Mohamed, Rachid, Olyaee, Mojtaba, Wood-Williams, April, Depue Brewbaker, Emily K., Thornhill, Andre, Gould, Mariana, Clasen, Kristen, Olsen, Jama, Simon, Violette C., Kamal, Ayesha, Volk, Sarah L., Merchant, Ambreen A., Lahooti, Ali, Furey, Nancy, Anderson, Gulsum, Hollander, Thomas, Vazquez, Alejandro, Li, Thomas Y., Hadley, Steven M., Chau, Millie, Mendoza, Robinson, Tangwongchai, Tida, Koza, Casey L., Geraci, Olivia, Nunez, Lizbeth, Waters, Alexander M., Durkalski-Mauldin, Valerie, Elmunzer, B Joseph, Foster, Lydia D, Coté, Gregory A, Edmundowicz, Steven A, Singh, Vikesh K, Kwon, Richard S, Scheiman, James M, Willingham, Field F, Keilin, Steven A, Papachristou, Georgios I, Gardner, Timothy B, Smith, Zachary L, Wang, Andrew Y, Saltzman, John R, and Spitzer, Rebecca L

Published
2024
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3. Impact of difficult biliary cannulation on post-ERCP pancreatitis: secondary analysis of the stent versus indomethacin trial dataset

Author

Han, Samuel, Zhang, Jingwen, Durkalski-Mauldin, Valerie, Foster, Lydia D., Serrano, Jose, Coté, Gregory A., Bang, Ji Young, Varadarajulu, Shyam, Singh, Vikesh K., Khashab, Mouen, Kwon, Richard S., Scheiman, James M., Willingham, Field F., Keilin, Steven A., Groce, J. Royce, Lee, Peter J., Krishna, Somashekar G., Chak, Amitabh, Slivka, Adam, Mullady, Daniel, Kushnir, Vladimir, Buxbaum, James, Keswani, Rajesh, Gardner, Timothy B., Wani, Sachin, Edmundowicz, Steven A., Shah, Raj J., Forbes, Nauzer, Rastogi, Amit, Ross, Andrew, Law, Joanna, Yachimski, Patrick, Chen, Yen-I, Barkun, Alan, Smith, Zachary L., Petersen, Bret T., Wang, Andrew Y., Saltzman, John R., Spitzer, Rebecca L., Spino, Cathie, Elmunzer, B. Joseph, and Papachristou, Georgios I.

Published
2024
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4. Trainee Participation and Outcomes in High-risk Endoscopic Retrograde Cholangiopancreatography: A Secondary Analysis of the Stent Versus Indomethacin Trial

Author

Serrano, Jose, Coté, Gregory A., Edmundowicz, Steven A., Shah, Raj, Bang, Ji Young, Varadarajulu, Shyam, Singh, Vikesh K., Khashab, Mouen, Kwon, Richard S., Scheiman, James M., Willingham, Field F., Keilin, Steven A., Papachristou, Georgios I., Chak, Amitabh, Slivka, Adam, Mullady, Daniel, Kushnir, Vladimir, Buxbaum, James, Keswani, Rajesh, Gardner, Timothy B., Forbes, Nauzer, Rastogi, Amit, Ross, Andrew, Law, Joanna, Yachimski, Patrick, Chen, Yen-I, Barkun, Alan, Smith, Zachary L., Petersen, Bret, Wang, Andrew Y., Saltzman, John R., Spitzer, Rebecca L., Gallegos, Jazmyne, Brennan, Case, Ordiah, Collins, Spino, Cathie, Wani, Sachin, Zhang, Jingwen, Foster, Lydia D., Durkalski-Mauldin, Valerie, and Elmunzer, B. Joseph

Published
2024
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6. Surgical and endoscopic management options for patients with GERD based on proton pump inhibitor symptom response: recommendations from an expert U.S. panel.

Author

Dunst, Christy, Edmundowicz, Steven, Jobe, Blair, Lipham, John, Lister, Dan, Canto, Marcia, Smith, Michael, Starpoli, Anthony, Triadafilopoulos, George, Watson, Thomas, Wilson, Erik, Pandolfino, John, Kaizer, Alexander, Van De Voorde, Zoe, Gawron, Andrew, Bell, Reginald, Abu Dayyeh, Barham, Buckley, F, Chang, Kenneth, and Yadlapati, Rena

Subjects
Adult, Aged, Endoscopy, Endoscopy, Gastrointestinal, Female, Fundoplication, Gastroesophageal Reflux, Humans, Laparoscopy, Los Angeles, Male, Middle Aged, Proton Pump Inhibitors, Treatment Outcome
Abstract

BACKGROUND AND AIMS: The objective of this study was to examine expert opinion and agreement on the treatment of distinct GERD profiles from surgical and therapeutic endoscopy perspectives. METHODS: We used the RAND/University of California, Los Angeles Appropriateness Method over 6 months (July 2018 to January 2019) to assess the appropriateness of antireflux interventions among foregut surgeons and therapeutic gastroenterologists. Patients with primary atypical or extraesophageal symptoms were not considered. Patient scenarios were grouped according to their symptom response to proton pump inhibitor (PPI) therapy. The primary outcome was appropriateness of an intervention. RESULTS: Antireflux surgery with laparoscopic fundoplication (LF) and magnetic sphincter augmentation (MSA) were ranked as appropriate for all complete and partial PPI responder scenarios. Transoral incisionless fundoplication was ranked as appropriate in complete and partial PPI responders without a hiatal hernia. Radiofrequency energy was not ranked as appropriate for complete or partial responders. There was lack of agreement between surgery and interventional gastroenterology groups on the appropriateness of LF and MSA for PPI nonresponders. Rankings for PPI nonresponders were similar when results from impedance-pH testing on PPI therapy were available, except that LF and MSA were not ranked as appropriate for PPI nonresponders if the impedance-pH study was negative. CONCLUSIONS: This work highlights areas of agreement for invasive therapeutic approaches for GERD and provides impetus for further interdisciplinary collaboration and trials to compare and generate novel and effective treatment approaches and care pathways, including the role of impedance-pH testing in PPI nonresponders.

Published
2020

7. Surgical and endoscopic management options for patients with GERD based on proton pump inhibitor symptom response: recommendations from an expert U.S. panel

Author

Gawron, Andrew J, Bell, Reginald, Abu Dayyeh, Barham K, Buckley, FP, Chang, Kenneth, Dunst, Christy M, Edmundowicz, Steven A, Jobe, Blair, Lipham, John C, Lister, Dan, Canto, Marcia Irene, Smith, Michael S, Starpoli, Anthony A, Triadafilopoulos, George, Watson, Thomas J, Wilson, Erik, Pandolfino, John E, Kaizer, Alexander, Van De Voorde, Zoe, and Yadlapati, Rena

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Digestive Diseases, Clinical Research, Oral and gastrointestinal, Adult, Aged, Endoscopy, Endoscopy, Gastrointestinal, Female, Fundoplication, Gastroesophageal Reflux, Humans, Laparoscopy, Los Angeles, Male, Middle Aged, Proton Pump Inhibitors, Treatment Outcome, Gastroenterology & Hepatology, Clinical sciences
Abstract

Background and aimsThe objective of this study was to examine expert opinion and agreement on the treatment of distinct GERD profiles from surgical and therapeutic endoscopy perspectives.MethodsWe used the RAND/University of California, Los Angeles Appropriateness Method over 6 months (July 2018 to January 2019) to assess the appropriateness of antireflux interventions among foregut surgeons and therapeutic gastroenterologists. Patients with primary atypical or extraesophageal symptoms were not considered. Patient scenarios were grouped according to their symptom response to proton pump inhibitor (PPI) therapy. The primary outcome was appropriateness of an intervention.ResultsAntireflux surgery with laparoscopic fundoplication (LF) and magnetic sphincter augmentation (MSA) were ranked as appropriate for all complete and partial PPI responder scenarios. Transoral incisionless fundoplication was ranked as appropriate in complete and partial PPI responders without a hiatal hernia. Radiofrequency energy was not ranked as appropriate for complete or partial responders. There was lack of agreement between surgery and interventional gastroenterology groups on the appropriateness of LF and MSA for PPI nonresponders. Rankings for PPI nonresponders were similar when results from impedance-pH testing on PPI therapy were available, except that LF and MSA were not ranked as appropriate for PPI nonresponders if the impedance-pH study was negative.ConclusionsThis work highlights areas of agreement for invasive therapeutic approaches for GERD and provides impetus for further interdisciplinary collaboration and trials to compare and generate novel and effective treatment approaches and care pathways, including the role of impedance-pH testing in PPI nonresponders.

Published
2020

9. Aspiration therapy for the treatment of obesity: 4-year results of a multicenter randomized controlled trial

Author

Thompson, Christopher C, Abu Dayyeh, Barham K, Kushnir, Vladimir, Kushner, Robert F, Jirapinyo, Pichamol, Schorr, Alan B, Aronne, Louis J, Amaro, Anastassia, Jaffe, David L, Schulman, Allison R, Early, Dayna, Stein, Adam C, Sharaiha, Reem, Edmundowicz, Steven A, Bohning, J Matthew, Jensen, Michael D, Shukla, Alpana P, Apovian, Caroline, Kim, Dong Wook, Tran, Daniel, Zarrinpar, Amir, Ryan, Michele B, Young, Meredith, Lowe, Abigail, Haas, Miki, Goldsmith, Heidi, McCrea, Jennifer, and Sullivan, Shelby

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Patient Safety, Digestive Diseases, Clinical Research, Nutrition, Prevention, Behavioral and Social Science, Obesity, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Oral and gastrointestinal, Cancer, Metabolic and endocrine, Adult, Bariatric Surgery, Body Mass Index, Drainage, Endoscopy, Gastrointestinal, Gastrostomy, Humans, Middle Aged, Obesity, Morbid, Treatment Outcome, Weight Loss, Endoscopic bariatric therapy, Aspiration therapy, Metabolic, Diet, Public Health and Health Services, Surgery, Clinical sciences, Public health
Abstract

BackgroundThe AspireAssist is the first Food and Drug Administration-approved endoluminal device indicated for treatment of class II and III obesity.ObjectivesWe earlier reported 1-year results of the PATHWAY study. Here, we report 4-year outcomes.SettingUnited States-based, 10-center, randomized controlled trial involving 171 participants with the treatment arm receiving Aspiration Therapy (AT) plus Lifestyle Therapy and the control arm receiving Lifestyle Therapy (2:1 randomization).MethodsAT participants were permitted to continue in the study for an additional year up to a maximum of 5 years providing they maintained at least 10% total weight loss (TWL) from baseline at each year end. For AT participants who continued the study, 5 medical monitoring visits were provided at weeks 60, 68, 76, 90, and 104 and thereafter once every 13 weeks up to week 260. Exclusion criteria were a history of eating disorder or evidence of eating disorder on a validated questionnaire. Follow-up weight, quality of life, and co-morbidities were compared with the baseline levels. In addition, rates of serious adverse event, persistent fistula, withdrawal, and A-tube replacement were reported. All analyses were performed using a per-protocol analysis.ResultsOf the 82 AT participants who completed 1 year, 58 continued to this phase of the trial. Mean baseline body mass index of these 58 patients was 41.6 ± 4.5 kg/m2. At the end of first year (at the beginning of the follow-up study), these 58 patients had a body mass index of 34.1 ± 5.4 kg/m2 and had achieved an 18.3 ± 8.0% TWL. On a per protocol basis, patients experienced 14.2%, 15.3%, 16.6%, and 18.7% TWL at 1, 2, 3, and 4 years, respectively (P < .01 for all). Forty of 58 patients (69%) achieved at least 10% TWL at 4 years or at time of study withdrawal. Improvements in quality of life scores and select cardiometabolic parameters were also maintained through 4 years. There were 2 serious adverse events reported in the second through fourth years, both of which resolved with removal or replacement of the A tube. Two persistent fistulas required surgical repair, representing approximately 2% of all tube removals. There were no clinically significant metabolic or electrolytes disorders observed, nor any evidence for development of any eating disorders.ConclusionsThe results of this midterm study have shown that AT is a safe, effective, and durable weight loss alternative for people with class II and III obesity and who are willing to commit to using the therapy and adhere to adjustments in eating behavior.

Published
2019

11. Combined Drainage and Protocolized Necrosectomy Through a Coaxial Lumen-apposing Metal Stent for Pancreatic Walled-off Necrosis: A Prospective Multicenter Trial

Author

Dayyeh, Barham K. Abu, Chandrasekhara, Vinay, Shah, Raj J., Easler, Jeffrey J., Storm, Andrew C., Topazian, Mark, Levy, Michael J., Martin, John A., Petersen, Bret T., Takahashi, Naoki, Edmundowicz, Steven, Hammad, Hazem, Wagh, Mihir S., Wani, Sachin, DeWitt, John, Bick, Benjamin, Gromski, Mark, Al Haddad, Mohammad, Sherman, Stuart, Merchant, Ambreen A., Peetermans, Joyce A., Gjata, Ornela, McMullen, Edmund, and Willingham, Field F.

Published
2023
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12. Competence in Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography, From Training Through Independent Practice

Author

Wani, Sachin, Keswani, Rajesh N, Han, Samuel, Aagaard, Eva M, Hall, Matthew, Simon, Violette, Abidi, Wasif M, Banerjee, Subhas, Baron, Todd H, Bartel, Michael, Bowman, Erik, Brauer, Brian C, Buscaglia, Jonathan M, Carlin, Linda, Chak, Amitabh, Chatrath, Hemant, Choudhary, Abhishek, Confer, Bradley, Coté, Gregory A, Das, Koushik K, DiMaio, Christopher J, Dries, Andrew M, Edmundowicz, Steven A, El Chafic, Abdul Hamid, El Hajj, Ihab, Ellert, Swan, Ferreira, Jason, Gamboa, Anthony, Gan, Ian S, Gangarosa, Lisa M, Gannavarapu, Bhargava, Gordon, Stuart R, Guda, Nalini M, Hammad, Hazem T, Harris, Cynthia, Jalaj, Sujai, Jowell, Paul S, Kenshil, Sana, Klapman, Jason, Kochman, Michael L, Komanduri, Srinadh, Lang, Gabriel, Lee, Linda S, Loren, David E, Lukens, Frank J, Mullady, Daniel, Muthusamy, V Raman, Nett, Andrew S, Olyaee, Mojtaba S, Pakseresht, Kavous, Perera, Pranith, Pfau, Patrick, Piraka, Cyrus, Poneros, John M, Rastogi, Amit, Razzak, Anthony, Riff, Brian, Saligram, Shreyas, Scheiman, James M, Schuster, Isaiah, Shah, Raj J, Sharma, Rishi, Spaete, Joshua P, Singh, Ajaypal, Sohail, Muhammad, Sreenarasimhaiah, Jayaprakash, Stevens, Tyler, Tabibian, James H, Tzimas, Demetrios, Uppal, Dushant S, Urayama, Shiro, Vitterbo, Domenico, Wang, Andrew Y, Wassef, Wahid, Yachimski, Patrick, Zepeda-Gomez, Sergio, Zuchelli, Tobias, and Early, Dayna

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Biomedical Imaging, Clinical Research, Digestive Diseases, Cholangiopancreatography, Endoscopic Retrograde, Clinical Competence, Endosonography, Humans, Learning Curve, Prospective Studies, Quality Indicators, Health Care, Quality Indicators, Advanced Endoscopy Training, Learning Curves, The EUS and ERCP Skills Assessment Tool, Neurosciences, Paediatrics and Reproductive Medicine, Gastroenterology & Hepatology, Clinical sciences, Nutrition and dietetics
Abstract

Background & aimsIt is unclear whether participation in competency-based fellowship programs for endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) results in high-quality care in independent practice. We measured quality indicator (QI) adherence during the first year of independent practice among physicians who completed endoscopic training with a systematic assessment of competence.MethodsWe performed a prospective multicenter cohort study of invited participants from 62 training programs. In phase 1, 24 advanced endoscopy trainees (AETs), from 20 programs, were assessed using a validated competence assessment tool. We used a comprehensive data collection and reporting system to create learning curves using cumulative sum analysis that were shared with AETs and trainers quarterly. In phase 2, participating AETs entered data into a database pertaining to every EUS and ERCP examination during their first year of independent practice, anchored by key QIs.ResultsBy the end of training, most AETs had achieved overall technical competence (EUS 91.7%, ERCP 73.9%) and cognitive competence (EUS 91.7%, ERCP 94.1%). In phase 2 of the study, 22 AETs (91.6%) participated and completed a median of 136 EUS examinations per AET and 116 ERCP examinations per AET. Most AETs met the performance thresholds for QIs in EUS (including 94.4% diagnostic rate of adequate samples and 83.8% diagnostic yield of malignancy in pancreatic masses) and ERCP (94.9% overall cannulation rate).ConclusionsIn this prospective multicenter study, we found that although competence cannot be confirmed for all AETs at the end of training, most meet QI thresholds for EUS and ERCP at the end of their first year of independent practice. This finding affirms the effectiveness of training programs. Clinicaltrials.gov ID NCT02509416.

Published
2018

14. Late Recurrence of Barrett’s Esophagus After Complete Eradication of Intestinal Metaplasia is Rare: Final Report From Ablation in Intestinal Metaplasia Containing Dysplasia Trial

Author

Cotton, Cary C, Wolf, W Asher, Overholt, Bergein F, Li, Nan, Lightdale, Charles J, Wolfsen, Herbert C, Pasricha, Sarina, Wang, Kenneth K, Shaheen, Nicholas J, Group, AIM Dysplasia Trial, Sampliner, Richard E, Fleischer, David E, Sharma, Virender K, Eisen, Glenn M, Fennerty, M Brian, Hunter, John G, Bronner, Mary P, Goldblum, John R, Bennett, Ana E, Mashimo, Hiroshi, Rothstein, Richard I, Gordon, Stuart R, Edmundowicz, Steven A, Muthusamy, V Raman, Chang, Kenneth J, Kimmey, Michael B, Spechler, Stuart J, Siddiqui, Ali A, Souza, Rhonda F, Infantolino, Anthony, Dumot, John A, Falk, Gary W, Jobe, Blair A, Hawes, Robert H, Hoffman, Brenda J, Sharma, Prateek, and Chak, Amitabh

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Prevention, Clinical Trials and Supportive Activities, Clinical Research, Digestive Diseases, Cancer, Oral and gastrointestinal, Aged, Barrett Esophagus, Catheter Ablation, Disease Progression, Esophagus, Female, Follow-Up Studies, Humans, Incidence, Kaplan-Meier Estimate, Male, Metaplasia, Middle Aged, Mucous Membrane, Population Surveillance, Prospective Studies, Recurrence, Time Factors, AIM Dysplasia Trial Group, HGD, High Grade Dysplasia, LGD, Long-term Outcome, Low Grade Dysplasia, Prognostic Factor, Neurosciences, Paediatrics and Reproductive Medicine, Gastroenterology & Hepatology, Clinical sciences, Nutrition and dietetics
Abstract

Background & aimsThe goal of treatment for Barrett's esophagus (BE) with dysplasia is complete eradication of intestinal metaplasia (CEIM). The long-term durability of CEIM has not been well characterized, so the frequency and duration of surveillance are unclear. We report results from a 5-year follow-up analysis of patients with BE and dysplasia treated by radiofrequency ablation (RFA) in the randomized controlled Ablation of Intestinal Metaplasia Containing Dysplasia (AIM) trial.MethodsParticipants for the AIM Dysplasia trial (18-80 years old) were recruited from 19 sites in the United States and had endoscopic evidence of non-nodular dysplastic BE ≤8 cm in length. Subjects (n = 127) were randomly assigned (2:1 ratio) to receive either RFA (entire BE segment ablated circumferentially) or a sham endoscopic procedure; patients in the sham group were offered RFA treatment 1 year later, and all patients were followed for 5 years. We collected data on BE recurrence (defined as intestinal metaplasia in the tubular esophagus) and dysplastic BE recurrence among patients who achieved CEIM. We constructed Kaplan-Meier estimates and applied parametric survival analysis to examine proportions of patients without any recurrence and without dysplastic recurrence.ResultsOf 127 patients in the AIM Dysplasia trial, 119 received RFA and met inclusion criteria. Of those 119, 110 (92%) achieved CEIM. Over 401 person-years of follow-up (mean, 3.6 years per patient; range, 0.2-5.8 years), 35 of 110 (32%) patients had recurrence of BE or dysplasia, and 19 (17%) had dysplasia recurrence. The incidence rate of BE recurrence was 10.8 per 100 person-years overall (95% CI, 7.8-15.0); 8.3 per 100 person-years among patients with baseline low-grade dysplasia (95% CI, 4.9-14.0), and 13.5 per 100 person-years among patients with baseline high-grade dysplasia (95% CI 8.8-20.7). The incidence rate of dysplasia recurrence was 5.2 per 100 person-years overall (95% CI 3.3-8.2); 3.3 per 100 person-years among patients with baseline low-grade dysplasia (95% CI 1.5-7.2), and 7.3 per 100 person-years among patients with baseline high-grade dysplasia (95% CI 4.2-12.5). Neither BE nor dysplasia recurred at a constant rate. There was a greater probability of recurrence in the first year following CEIM than in the following 4 years combined.ConclusionsIn this analysis of prospective cohort data from the AIM Dysplasia trial, we found BE to recur after CEIM by RFA in almost one third of patients with baseline dysplastic disease; most recurrences occurred during the first year after CEIM. However, patients who achieved CEIM and remained BE free at 1 year after RFA had a low risk of BE recurrence. Studies are needed to determine when surveillance can be decreased or discontinued; our study did not identify any BE or dysplasia recurrence after 4 years of surveillance.

Published
2017

20. Endoscopic Ultrasound Placement of Preloaded Fiducial Markers Shortens Procedure Time Compared to Back-Loaded Markers

Author

Machicado, Jorge D., Obuch, Joshua C., Goodman, Karyn A., Schefter, Tracey E., Frakes, Jessica, Hoffe, Sarah, Latifi, Kutjim, Simon, Violette C., Santangelo, Tess, Ezekwe, Eze, Edmundowicz, Steven A., Brauer, Brian C., Shah, Raj J., Hammad, Hazem T., Wagh, Mihir S., Attwell, Augustin, Han, Samuel, Klapman, Jason, and Wani, Sachin

Published
2019
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21. Anatomic location of Barrett’s esophagus recurrence after endoscopic eradication therapy: development of a simplified surveillance biopsy strategy

Author

Omar, Mahmoud, Thaker, Adarsh M., Wani, Sachin, Simon, Violette, Ezekwe, Eze, Boniface, Megan, Edmundowicz, Steven, Obuch, Joshua, Cinnor, Birtukan, Brauer, Brian C., Wood, Mariah, Early, Dayna S., Lang, Gabriel D., Mullady, Daniel, Hollander, Thomas, Kushnir, Vladimir, Komanduri, Srinadh, and Muthusamy, V. Raman

Published
2019
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22. A phase III, multicenter, prospective, single-blinded, noninferiority, randomized controlled trial on the performance of a novel esophageal stent with an antireflux valve (with video)

Author

Dua, Kulwinder S., DeWitt, John M., Kessler, William R., Diehl, David L., Draganov, Peter V., Wagh, Mihir S., Kahaleh, Michel, Wong Kee Song, Louis M., Khara, Harshit S., Khan, Abdul H., Aburajab, Murad M., Ballard, Darren, Forsmark, Chris E., Edmundowicz, Steven A., Brauer, Brian C., Tyberg, Amy, Buttar, Najtej S., and Adler, Douglas G.

Published
2019
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24. Setting minimum standards for training in EUS and ERCP: results from a prospective multicenter study evaluating learning curves and competence among advanced endoscopy trainees

Author

Wani, Sachin, Han, Samuel, Simon, Violette, Hall, Matthew, Early, Dayna, Aagaard, Eva, Abidi, Wasif M., Banerjee, Subhas, Baron, Todd H., Bartel, Michael, Bowman, Erik, Brauer, Brian C., Buscaglia, Jonathan M., Carlin, Linda, Chak, Amitabh, Chatrath, Hemant, Choudhary, Abhishek, Confer, Bradley, Coté, Gregory A., Das, Koushik K., DiMaio, Christopher J., Dries, Andrew M., Edmundowicz, Steven A., El Chafic, Abdul Hamid, El Hajj, Ihab, Ellert, Swan, Ferreira, Jason, Gamboa, Anthony, Gan, Ian S., Gangarosa, Lisa, Gannavarapu, Bhargava, Gordon, Stuart R., Guda, Nalini M., Hammad, Hazem T., Harris, Cynthia, Jalaj, Sujai, Jowell, Paul, Kenshil, Sana, Klapman, Jason, Kochman, Michael L., Komanduri, Sri, Lang, Gabriel, Lee, Linda S., Loren, David E., Lukens, Frank J., Mullady, Daniel, Muthusamy, Raman V., Nett, Andrew S., Olyaee, Mojtaba S., Pakseresht, Kavous, Perera, Pranith, Pfau, Patrick, Piraka, Cyrus, Poneros, John M., Rastogi, Amit, Razzak, Anthony, Riff, Brian, Saligram, Shreyas, Scheiman, James M., Schuster, Isaiah, Shah, Raj J., Sharma, Rishi, Spaete, Joshua P., Singh, Ajaypal, Sohail, Muhammad, Sreenarasimhaiah, Jayaprakash, Stevens, Tyler, Tabibian, James H., Tzimas, Demetrios, Uppal, Dushant S., Urayama, Shiro, Vitterbo, Domenico, Wang, Andrew Y., Wassef, Wahid, Yachimski, Patrick, Zepeda-Gomez, Sergio, Zuchelli, Tobias, and Keswani, Rajesh N.

Published
2019
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25. Randomized sham-controlled trial of the 6-month swallowable gas-filled intragastric balloon system for weight loss

Author

Sullivan, Shelby, Swain, James, Woodman, George, Edmundowicz, Steven, Hassanein, Tarek, Shayani, Vafa, Fang, John C., Noar, Mark, Eid, George, English, Wayne J., Tariq, Nabil, Larsen, Michael, Jonnalagadda, Sreenivasa S., Riff, Dennis S., Ponce, Jaime, Early, Dayna, Volckmann, Eric, Ibele, Anna R., Spann, Matthew D., Krishnan, Kumar, Bucobo, Juan Carlos, and Pryor, Aurora

Published
2018
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26. The timing of recurrence after endoscopic papillectomy

Author

Han, Samuel, primary, Turkeltaub, Joshua A., additional, Jonas, Daniel, additional, Attwell, Augustin R., additional, Duloy, Anna M., additional, Edmundowicz, Steven A., additional, Hammad, Hazem T., additional, Wagh, Mihir S., additional, Wani, Sachin, additional, and Shah, Raj J., additional

Published
2023
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33. TRAINEE PARTICIPATION AND OUTCOMES IN HIGH-RISK ERCP: A SECONDARY ANALYSIS OF THE STENT VERSUS INDOMETHACIN (SVI) TRIAL DATASET.

Author

Wani, Sachin, Zhang, Jingwen, Foster, Lydia, Serrano, Jose, Cote, Gregory, Edmundowicz, Steven, Shah, Raj, Bang, Ji Young, Varadarajulu, Shyam, Singh, Vikesh, Khashab, Mouen, Kwon, Richard, Scheiman, James, Willingham, Field, Keilin, Steven, Papachristou, Georgios, Chak, Amitabh, Slivka, Adam, Mullady, Daniel, and Kushnir, Vladimir

Published
2024
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36. NEARLY 25% OF BARRETT’S ESOPHAGUS WITH LOW-GRADE DYSPLASIA PATIENTS REFERRED FROM THE COMMUNITY HARBOR HIGH-GRADE DYSPLASIA OR ESOPHAGEAL ADENOCARCINOMA

Author

Pokala, Sridevi, primary, O'Hara, Jack, additional, Gallegos, Jazmyne, additional, Tarter, Wyatt, additional, Jojo, Justeena, additional, Muthusamy, V. Raman, additional, Rastogi, Amit, additional, Kushnir, Vladimir, additional, Zafar, Nazish, additional, Sloan, Erika, additional, Mendoza, Robinson, additional, Hammad, Hazem, additional, Wagh, Mihir, additional, Edmundowicz, Steven, additional, Komanduri, Sri, additional, and Wani, Sachin, additional

Published
2023
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37. A Prospective Multicenter Study Evaluating Learning Curves and Competence in Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography Among Advanced Endoscopy Trainees: The Rapid Assessment of Trainee Endoscopy Skills Study

Author

Wani, Sachin, Keswani, Rajesh, Hall, Matt, Han, Samuel, Ali, Meer Akbar, Brauer, Brian, Carlin, Linda, Chak, Amitabh, Collins, Dan, Cote, Gregory A., Diehl, David L., DiMaio, Christopher J., Dries, Andrew, El-Hajj, Ihab, Ellert, Swan, Fairley, Kimberley, Faulx, Ashley, Fujii-Lau, Larissa, Gaddam, Srinivas, Gan, Seng-Ian, Gaspar, Jonathan P., Gautamy, Chitiki, Gordon, Stuart, Harris, Cynthia, Hyder, Sarah, Jones, Ross, Kim, Stephen, Komanduri, Srinadh, Law, Ryan, Lee, Linda, Mounzer, Rawad, Mullady, Daniel, Muthusamy, V. Raman, Olyaee, Mojtaba, Pfau, Patrick, Saligram, Shreyas, Piraka, Cyrus, Rastogi, Amit, Rosenkranz, Laura, Rzouq, Fadi, Saxena, Aditi, Shah, Raj J., Simon, Violette C., Small, Aaron, Sreenarasimhaiah, Jayaprakash, Walker, Andrew, Wang, Andrew Y., Watson, Rabindra R., Wilson, Robert H., Yachimski, Patrick, Yang, Dennis, Edmundowicz, Steven, and Early, Dayna S.

Published
2017
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38. ASGE EndoVators Summit: Defining the role and value of endoscopic therapies in obesity management

Author

Ryou, Marvin, McQuaid, Kenneth R., Thompson, Christopher C., Edmundowicz, Steven, Mergener, Klaus, Abu Dayyeh, Barham, Apovian, Caroline, Burke, Carol, Chand, Bipan, Chandraker, Anil, Deas, Thomas, Dietz, William, Dunkin, Brian, Ernest, Opella, Faigel, Douglas, Garber, Shawn, Hamdy, Osama, Kaplan, Lee, Kumar, Nitin, Kushner, Robert, Larsen, Michael C., Lerner, Herbert, Littenberg, Glenn, Mantzoros, Christos, Mattar, Samer, Moore, Rachel, Rinella, Mary, Rothstein, Richard, Schillinger, Dean, Spring, Bonnie, Sullivan, Shelby, Tice, Jeffrey, Vargo, John, Wilson, Erik, Woods, Karen, and Zundel, Natan

Published
2017
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39. Increasing Number of Passes Beyond 4 Does Not Increase Sensitivity of Detection of Pancreatic Malignancy by Endoscopic Ultrasound–Guided Fine-Needle Aspiration

Author

Mohamadnejad, Mehdi, Mullady, Daniel, Early, Dayna S., Collins, Brian, Marshall, Carrie, Sams, Sharon, Yen, Roy, Rizeq, Mona, Romanas, Maria, Nawaz, Samia, Ulusarac, Ozlem, Hollander, Thomas, Wilson, Robert H., Simon, Violette C., Kushnir, Vladimir, Amateau, Stuart K., Brauer, Brian C., Gaddam, Srinivas, Azar, Riad R., Komanduri, Srinadh, Shah, Raj, Das, Ananya, Edmundowicz, Steven, Muthusamy, V. Raman, Rastogi, Amit, and Wani, Sachin

Published
2017
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40. Development of quality indicators for endoscopic eradication therapies in Barrett’s esophagus: the TREAT-BE (Treatment with Resection and Endoscopic Ablation Techniques for Barrett’s Esophagus) Consortium

Author

Wani, Sachin, Muthusamy, V. Raman, Shaheen, Nicholas J., Yadlapati, Rena, Wilson, Robert, Abrams, Julian A., Bergman, Jacques, Chak, Amitabh, Chang, Kenneth, Das, Ananya, Dumot, John, Edmundowicz, Steven A., Eisen, Glenn, Falk, Gary W., Fennerty, M. Brian, Gerson, Lauren, Ginsberg, Gregory G., Grande, David, Hall, Matt, Harnke, Ben, Inadomi, John, Jankowski, Janusz, Lightdale, Charles J., Makker, Jitin, Odze, Robert D., Pech, Oliver, Sampliner, Richard E., Spechler, Stuart, Triadafilopoulos, George, Wallace, Michael B., Wang, Kenneth, Waxman, Irving, and Komanduri, Srinadh

Published
2017
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42. Contributors

Author

Adler, Douglas G., primary, Ahlawat, Sushil K., additional, Ahmad, Jawad, additional, Al-Kawas, Firas H., additional, Anderson, Michelle A., additional, de Almeida Artifon, Everson Luiz, additional, de Andrade Lima Cabral, João Guilherme Guerra, additional, Baillie, John, additional, Banerjee, Rupa, additional, Baron, Todd H., additional, Basar, Omer, additional, Benias, Petros C., additional, Boškoski, Ivo, additional, Bourke, Michael J., additional, Brauer, Brian C., additional, Brugge, William R., additional, Buscaglia, Jonathan M., additional, Carr-Locke, David L., additional, Chahal, Prabhleen, additional, Chandran, Sujievvan, additional, Chen, Yen-I, additional, Choi, Anthony J., additional, Cohen, Jonah, additional, Costamagna, Guido, additional, Coté, Gregory A., additional, Cotton, Peter, additional, Das, Koushik K., additional, Devière, Jacques, additional, Edmundowicz, Steven A., additional, El Hajj, Ihab I., additional, Faigel, Douglas O., additional, Familiari, Pietro, additional, Fockens, Paul, additional, Fogel, Evan L., additional, Fox, Victor L., additional, Freeman, Martin L., additional, Gan, S. Ian, additional, Gelrud, Andres, additional, Ginsberg, Gregory G., additional, Gluck, Michael, additional, Goh, Khean-Lee, additional, Hawes, Robert H., additional, Higa, Jennifer T., additional, Holmes, Jordan D., additional, Irani, Shayan, additional, Itoi, Takao, additional, Jamidar, Priya A., additional, Kahaleh, Michel, additional, Kalloo, Anthony N., additional, Khashab, Mouen A., additional, Kochman, Michael L., additional, Kodama, Tadashi, additional, Korman, Andrew, additional, Kortan, Paul, additional, Koshitani, Tatsuya, additional, Kozarek, Richard A., additional, Larsen, Michael, additional, Lau, James Y.W., additional, Law, Ryan, additional, Lehman, Glen, additional, Leung, Joseph W., additional, Ligresti, Dario, additional, Lin, Eugene, additional, Lo, Simon K., additional, Ma, Michael X., additional, Maple, John T., additional, Mariani, Alberto, additional, May, Gary, additional, McHenry, Lee, additional, Mizrahi, Meir, additional, Mounzer, Rawad, additional, Muniraj, Thiruvengadam, additional, Neuhaus, Horst, additional, Norton, Ian D., additional, Perez-Miranda, Manuel, additional, Petersen, Bret T., additional, Pleskow, Douglas, additional, Purnak, Tugrul, additional, Rao, G. Venkat, additional, Razzak, Anthony, additional, Reddy, D. Nageshwar, additional, Ross, Andrew S., additional, Sarkisian, Alexander M., additional, Schueler, Beth, additional, Seo, Dong Wan, additional, Shah, Raj J., additional, Sharaiha, Reem Z., additional, Sherman, Stuart, additional, Shim, Chan Sup, additional, Singh, Ajaypal, additional, Slivka, Adam, additional, Solomon, Sanjeev, additional, Song, Tae Jun, additional, Srinivasan, Indu, additional, Sung, Joseph J.Y., additional, Tarantino, Ilaria, additional, Tarnasky, Paul R., additional, Testoni, Pier Alberto, additional, Tobin, Catherine D., additional, Topazian, Mark, additional, Wani, Sachin, additional, Wong, John C.T., additional, and Yen, Andrew W., additional

Published
2019
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45. Soft self-expandable metal stent to treat painful pancreatic duct strictures secondary to chronic pancreatitis: a prospective multicenter trial

Author

Sherman, Stuart, primary, Kozarek, Richard A., additional, Costamagna, Guido, additional, Reddy, D. Nageshwar, additional, Tarnasky, Paul, additional, Shah, Raj J., additional, Slivka, Adam, additional, Fogel, Evan, additional, Watkins, James, additional, Delhaye, Myriam, additional, Irani, Shayan S., additional, Tringali, Andrea, additional, Lakhtakia, Sundeep, additional, Kedia, Prashant, additional, Edmundowicz, Steven, additional, Peetermans, Joyce A., additional, Rousseau, Matthew J., additional, and Devière, Jacques, additional

Published
2023
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46. Long-term Outcomes of Patients Receiving a Magnetic Sphincter Augmentation Device for Gastroesophageal Reflux

Author

Ganz, Robert A., Edmundowicz, Steven A., Taiganides, Paul A., Lipham, John C., Smith, C. Daniel, DeVault, Kenneth R., Horgan, Santiago, Jacobsen, Garth, Luketich, James D., Smith, Christopher C., Schlack-Haerer, Steven C., Kothari, Shanu N., Dunst, Christy M., Watson, Thomas J., Peters, Jeffrey, Oelschlager, Brant K., Perry, Kyle A., Melvin, Scott, Bemelman, Willem A., Smout, André J.P.M., and Dunn, Dan

Published
2016
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47. Incidence of residual choledocholithiasis detected by intraoperative cholangiography at the time of laparoscopic cholecystectomy in patients having undergone preoperative ERCP

Author

Pierce, Richard, Jonnalagadda, Sreenivasa, Spitler, Jennifer, Tessier, Deron, Liaw, Jane, Lall, Shelly, Melman, Lora, Frisella, Margaret, Todt, Laura, Brunt, L., Halpin, Valerie, Eagon, J., Edmundowicz, Steven, and Matthews, Brent

Abstract

Abstract: Introduction: The purpose of this study is to determine the incidence of residual common bile duct (CBD) stones after preoperative ERCP for choledocholithiasis and to evaluate the utility of routine intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC) in this patient population. Methods: All patients who underwent preoperative ERCP and interval LC with IOC from 5/96 to 12/05 were reviewed under an Institutional Review Board (IRB)-approved protocol. Data collected included all radiologic imaging, laboratory values, clinical and pathologic diagnoses, and results of preoperative ERCP and LC with IOC. Standard statistical analyses were used with significance set at p < 0.05. Results: A total of 227 patients (male:female 72:155, mean age 51.9 years) underwent preoperative ERCP for suspicion of choledocholithiasis. One hundred and eighteen patients were found to have CBD stones on preoperative ERCP, and of these, 22 had choledocholithiasis diagnosed on IOC during LC. However, two patients had residual stones on completion cholangiogram after ERCP and were considered to have retained stones. Therefore, 20 patients overall were diagnosed with either interval passage of stones into the CBD or a false-negative preoperative ERCP. In the 109 patients without CBD stones on preoperative ERCP, nine patients had CBD stones on IOC during LC, an 8.3% incidence of interval passage of stones or false-negative preoperative ERCP. In both groups, there was no correlation (p > 0.05) between an increased incidence of CBD stones on IOC and a longer time interval between ERCP and LC, performance of sphincterotomy, incidence of cystic duct stones, or pathologic diagnosis of cholelithiasis. Conclusions: The overall incidence of retained or newly passed CBD stones on IOC during LC after a preoperative ERCP is 12.9%. Although the natural history of residual CBD stones after preoperative ERCP is not known, the routine use of IOC should be considered in patients with CBD stones on preoperative ERCP undergoing an interval LC.

Published
2024
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