Search

Your search keyword '"Esad Koklu"' showing total 4 results
Start Over Author "Esad Koklu" Publication Year Range Last 10 years
4 results on '"Esad Koklu"'

1. Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society.

Author

Esin Koc, Nihal Demirel, Ahmet Yagmur Bas, Dilek Ulubas Isik, Ibrahim Murat Hirfanoglu, Turan Tunc, Fatma Nur Sari, Guner Karatekin, Ramazan Ozdemir, Huseyin Altunhan, Merih Cetinkaya, Beyza Ozcan, Servet Ozkiraz, Sebnem Calkavur, Kadir Serafettin Tekgunduz, Ayhan Tastekin, Ferda Ozlu, Banu Mutlu Ozyurt, Ahmet Ozdemir, Bilin Cetinkaya, Yasar Demirelli, Esad Koklu, Ulker Celik, Nuriye Tarakci, Didem Armangil, Emel Okulu, Fatma Narter, Birgul Mutlu, Mustafa Kurthan Mert, Ali Bulbul, Huseyin Selim Asker, Ozgun Uygur, Ilker Sait Uslu, Sabahattin Ertugrul, Cumhur Aydemir, Hasan Tolga Celik, Kazim Kucuktasci, Selda Arslan, Hacer Ergin, Aysegul Zenciroglu, Sadik Yurttutan, Aysen Orman, Oguz Tuncer, Beril Yasa, Betul Acunas, Sahin Takci, Zeynel Gokmen, Hilal Ozkan, Serdar Comert, Nuran Ustun, Mehmet Mutlu, Bilge Tanyeri Bayraktar, Leyla Bilgin, Funda Tuzun, Ozge Aydemir, Tugba Gursoy, Arzu Akdag, Asli Memisoglu, Emrah Can, Demet Terek, Serdar Beken, Ozden Turan, Nilufer Guzoglu, Rahmi Ors, Yusuf Kale, Berna Hekimoglu, Hakan Aylanc, Funda Eroglu, Suzan Sahin, Murat Konak, Dilek Sarici, Ilknur Kilic, and Nilay Hakan

Subjects
Medicine, Science
Abstract

ObjectiveTo investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey.Material and methodsA prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of ≤1500 g were collected for infants who survived.ResultsData from 69 NICUs were obtained. The mean birth weight and gestational age were 1137±245 g and 29±2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers.ConclusionThe present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.

Published
2019
Full Text
View/download PDF

2. Transcutaneous Bilirubin Levels and Risk of Significant Hyperbilirubinemia in Early-Term and Term Newborns

Author

Yüksel Yaşartekin, Serdar Umit Sarici, Dilek Sarici, Murat Özcan, Melis Akpinar, Esad Koklu, Muhittin Serdar, and Demet Altun

Subjects
Pediatrics, medicine.medical_specialty, Early Term, Critical Care Nursing, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Neonatal Screening, 030225 pediatrics, Transcutaneous bilirubinometry, Maternity and Midwifery, medicine, Humans, Prospective Studies, Tertiary level, Hyperbilirubinemia, 030219 obstetrics & reproductive medicine, Transcutaneous bilirubin, business.industry, Infant, Newborn, Bilirubin, Jaundice, Phototherapy, Increased risk, medicine.symptom, business, Cohort study
Abstract

To compare the course of the transcutaneous bilirubin (TcB) values of early-term newborns with those of term newborns in the first month of life and to investigate whether early-term newborns have an increased risk of significant hyperbilirubinemia requiring treatment.A prospective, controlled cohort analysis.A tertiary level mother-child birth and health care center.Four hundred early-term (37 0/7 to 38 6/7 weeks) and 320 term (39 0/7 to 41 6/7 weeks) newborns born during a 27-month period.A total of six TcB measurements in a longitudinal manner were made in early-term and term newborns: the first two at 6 and 48 hours after birth and the next four on routine examination days (Days 4, 7, 15, and 30). Demographic characteristics, values of daily TcB measurements, number of newborns with significant hyperbilirubinemia, and risk of jaundice requiring treatment were compared between the two groups.All six TcB values were significantly greater in the early-term group than in the term group (p .001 for each). Early-term newborns had a statistically significant increased risk of jaundice requiring treatment compared to term newborns (risk ratio = 1.91; 95% confidence interval [1.23-2.96]; p = .0046). Results of the repeated-measures analysis of variance and post hoc adjusted multiple comparison analysis showed that TcB levels increased to and peaked at 96 hours after birth and then gradually decreased to baseline (first measurement) levels at 30 days after birth in each group.Early-term newborns should not be treated as full-term newborns because they have significantly higher TcB levels. These newborns should be closely monitored for pathologic jaundice because they have increased risk for significant hyperbilirubinemia requiring phototherapy.

Published
2021

3. Early neonatal outcomes of very-low-birthweight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

Author

Hüseyin Selim Asker, Emrah Can, Cumhur Aydemir, Betül Acunaş, Ali Bulbul, Turan Tunc, Kadir Şerafettin Tekgündüz, Hasan Tolga Çelik, Şahin Takcı, Ramazan Ozdemir, Ahmet Ozdemir, Mehmet Mutlu, Ferda Özlü, Yasar Demirelli, Beyza Ozcan, Rahmi Ors, Fatma Nur Sari, Ilknur Kilic, Guner Karatekin, Dilek Ulubas Isik, Banu Mutlu Özyurt, Berna Hekimoğlu, Sabahattin Ertuğrul, Murat Konak, Selda Arslan, Nuriye Tarakci, Ozgun Uygur, Serdar Cömert, Sadık Yurttutan, Kazim Kucuktasci, Emel Okulu, Arzu Akdag, Nilay Hakan, Nilüfer Güzoğlu, Tugba Gursoy, Hakan Aylanç, Şebnem Çalkavur, Asli Memisoglu, Ayşegül Zenciroğlu, Bilin Cetinkaya, Serdar Beken, Ozge Aydemir, Hacer Ergin, Ibrahim Murat Hirfanoglu, Yusuf Kale, Didem Armangil, Suzan Sahin, Bilge Tanyeri Bayraktar, Özden Turan, Huseyin Altunhan, Servet Ozkiraz, İlker Uslu, Nihal Demirel, Funda Eroglu, Zeynel Gokmen, Aysen Orman, Leyla Bilgin, Esin Koç, Beril Yasa, Demet Terek, Funda Tuzun, Esad Koklu, Nuran Üstün, Birgul Mutlu, Ahmet Yagmur Bas, Merih Cetinkaya, Hilal Özkan, Fatma Narter, Mustafa Kurthan Mert, Ayhan Tastekin, Ulker Celik, Dilek Sarici, Oğuz Tuncer, KOÇ E., DEMİREL N., BAŞ A. Y., Isik D. U., HIRFANOĞLU İ. M., Tunc T., Sari F. N., Karatekin G., ÖZDEMİR R., Altunhan H., et al., Ege Üniversitesi, MÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Hakan, Nilay, Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı, Ertuǧrul, Sabahattin, Selçuk Üniversitesi, OMÜ, Gürsoy, Tuğba (ORCID 0000-0002-6084-4067 & YÖK ID 214691), Koç, Esin, Demirel, Nihal, Baş, Ahmet Yağmur, Işık, Dilek Ulubaş, Hirfanoğlu, İbrahim Murat, Tunc, Turan, Sarı, Fatma Nur, Karatekin, Güner, Özdemir, Ramazan, Altunhan, Hüseyin, Çetinkaya, Merih, Özcan, Beyza, Özkiraz, Servet, Çalkavur, Sebnem, Tekgündüz, Kadir Şerafettin, Taştekin, Ayhan, Özlü, Ferda, Özyurt, Banu Mutlu, Özdemir, Ahmet, Çetinkaya, Bilin, Demirelli, Yaşar, Köklü, Esad, Çelik, Ülker, Tarakçı, Nuriye, Armangil, Didem, Okulu, Emel, Narter, Fatma, Mutlu, Birgul, Mert, Mustafa Kurthan, Bülbül, Ali, Asker, Hüseyin Selim, Uygur, ÖzgÜn, Uslu, İlker Sait, Ertuğrul, Sabahattin, Aydemir, Cumhur, Çelik, Hasan Tolga, Küçüktaşçı, Kazım, Arslan, Selda, Ergin, Hacer, Zenciroğlu, Aysegül, Yurttutan, Sadık, Orman, Ayşen, Tuncer, Oğuz, Yaşa, Beril, Acunas, Betül, Takci, Şahin, Gökmen, Zeynel, Özkan, Hilal, Cömert, Serdar, Üstün, Nuran, Mutlu, Mehmet, Bayraktar, Bilge Tanyeri, Bilgin, Leyla, Tuzun, Funda, Aydemir, Özge, Akdağ, Arzu, Memisoğlu, Aslı, Can, Emrah, Terek, Demet, Beken, Serdar, Turan, Özden, Güzoğlu, Nilüfer, Örs, Rahmi, Kale, Yusuf, Hekimoğlu, Berna, Aylanc, Hakan, Eroğlu, Funda, Şahin, Suzan, Konak, Murat, Sarıcı, Dilek, Kılıç, İlknur, School of Medicine, Acibadem University Dspace, KKÜ, and Kırıkkale Üniversitesi

Subjects
Male, Turkey, Temel Bilimler (SCI), very low birth weight, ÇOK DİSİPLİNLİ BİLİMLER, Pathology and Laboratory Medicine, blood culture, Pediatrics, Infant, Newborn, Diseases, lung dysplasia, sepsis, Families, 0302 clinical medicine, newborn, Pregnancy, Birth Weight, Medicine, Prospective Studies, Children, [Anahtar Kelime Yok], Organic Compounds, adult, steroid, Pregnancy Outcome, clinical trial, Retinopathy of prematurity, cohort analysis, Bronchopulmonary dysplasia, Necrotizing enterocolitis, Morbidity, Mortality, Health, Prematurity, Infections, Countries, Distress, Sepsis, Physical Sciences, disease severity, prospective study, survival rate, medicine.medical_specialty, Science, Article, patent ductus arteriosus, 03 medical and health sciences, Signs and Symptoms, turkey (bird), Intensive Care Units, Neonatal, Intensive care, Humans, Retinopathy of Prematurity, human, Retinopathy, necrotizing enterocolitis, MULTIDISCIPLINARY SCIENCES, Chemical Compounds, Biology and Life Sciences, Neonates, Doğa Bilimleri Genel, medicine.disease, major clinical study, neonatal intensive care unit, Health Care, hospital discharge, Ophthalmology, Low birth weight, multicenter study, NATURAL SCIENCES, GENERAL, Population Groupings, Health Statistics, Neonatology, Developmental Biology, genetic structures, morbidity, hemodynamics, Neonatal Care, Turkey (republic), Medicine and Health Sciences, Infant, Very Low Birth Weight, 030212 general & internal medicine, gestational age, Prospective cohort study, Science and technology, Multidisciplinary, Temel Bilimler, Gestational age, newborn disease, Chemistry, female, Natural Sciences (SCI), brain hemorrhage, Retinal Disorders, Steroids, Female, Neonatal Sepsis, newborn morbidity, medicine.symptom, Natural Sciences, Infants, Research Article, Adult, Birth weight, Gestational Age, Turkish Neonatal Society, Diagnostic Medicine, 030225 pediatrics, retinopathy, controlled study, outcome assessment, perinatal period, Multidisipliner, business.industry, Organic Chemistry, prematurity, Infant, Newborn, infant, Age Groups, People and Places, Study, business, Early Neonatal Outcomes
Abstract

Beken, Serdar/0000-0002-8609-2684; BAS, AHMET YAGMUR/0000-0002-1329-2167; Bulbul, Ali/0000-0002-3510-3056; Karatekin, Guner/0000-0001-7112-0323, WOS: 000534242500056, PubMed: 31851725, Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. the study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. the mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers. Conclusion the present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs., Turkish Neonatal Society [2-2016]; Turkish Neonatal Society, This study was supported by the Turkish Neonatal Society, http://www.neonatology.org.tr, number 2-2016, received by AYB. Turkish Neonatal Society funded the study's online registry system. the funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Published
2019

4. Transcutaneous Bilirubin Levels during the First Month of Life in Term and Late-preterm Newborns

Author

Esad Koklu, Muhittin Serdar, Serdar Umit Sarici, and Omer Gunes

Subjects
Male, Pediatrics, medicine.medical_specialty, Percentile, Infant, Premature, Diseases, 03 medical and health sciences, 0302 clinical medicine, Neonatal Screening, 030225 pediatrics, Late preterm, Medicine, Humans, 030212 general & internal medicine, Risk status, Transcutaneous bilirubin, business.industry, Infant, Newborn, Bilirubin, Nomogram, Jaundice, Nomograms, Infectious Diseases, Pediatrics, Perinatology and Child Health, Female, medicine.symptom, Hyperbilirubinemia, Neonatal, business, Biomarkers, Infant, Premature, Transcutaneous bilirubinometer, Follow-Up Studies
Abstract

OBJECTIVE We aimed to develop a transcutaneous bilirubin (TcB) nomogram for assessment of the risk of significant hyperbilirubinemia and prolonged jaundice during the first month of life in term and late-preterm Turkish newborns. METHODS On the basis of the daily (3rd, 7th, 15th and 30th days) TcB measurements, 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentiles, and 5 percentile tracks were obtained. TcB measurements were made by a transcutaneous bilirubinometer (JaundiceDetector JH20-1C). RESULTS We screened 729 healthy term and late-preterm Turkish infants 3-30 days old and developed a nomogram of TcB levels. TcB level was ≥5 mg/dl in 41.98% and 25.9% of infants at age 15.0 ± 2.1 days and 30.9 ± 2.6 days, respectively. The TcB measurement-based nomogram values of the 97th percentiles (cutoff values) at age 15.0 ± 2.1 and 30.9 ± 2.6 days were 11.4 (10.82-12.13) mg/dl and 10.0 (9.40-10.70) mg/dl, respectively. CONCLUSION This nomogram can be used to determine the risk status of Turkish newborns regarding significant hyperbilirubinemia and prolonged jaundice on the basis of TcB measurement in the first month of life.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results