1,474 results on '"Fischer, D"'
Search Results
2. Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort
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Samudra, Niyatee, Fischer, D Luke, Lenio, Steven, Lago, Argentina Lario, Ljubenkov, Peter A, Rojas, Julio C, Seeley, William W, Spina, Salvatore, Staffaroni, Adam M, Tablante, Jonathan, Wekselman, Fattin, Lamoureux, Jennifer, Concha‐Marambio, Luis, Grinberg, Lea T, Boxer, Adam L, and VandeVrede, Lawren
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Biomedical and Clinical Sciences ,Clinical Sciences ,Brain Disorders ,Acquired Cognitive Impairment ,Neurosciences ,Neurodegenerative ,Dementia ,4.2 Evaluation of markers and technologies ,Detection ,screening and diagnosis ,Neurological ,Humans ,alpha-Synuclein ,Lewy Body Disease ,Female ,Male ,Aged ,Autopsy ,Sensitivity and Specificity ,Cohort Studies ,Amygdala ,Aged ,80 and over ,Biomarkers ,Middle Aged ,alpha synuclein ,cerebrospinal fluid ,dementia with Lewy bodies ,Lewy body disease ,seed amplification assay ,Geriatrics ,Clinical sciences ,Biological psychology - Abstract
IntroductionLewy body disease (LBD) is a common primary or co-pathology in neurodegenerative syndromes. An alpha-synuclein seed amplification assay (αSyn-SAA) is clinically available, but clinical performance, especially lower sensitivity in amygdala-predominant cases, is not well understood.MethodsAntemortem CSF from neuropathology-confirmed LBD cases was tested with αSyn-SAA (N = 56). Diagnostic performance and clinicopathological correlations were examined.ResultsSimilar to prior reports, sensitivity was 100% for diffuse and transitional LBD (9/9), and overall specificity was 96.3% (26/27). Sensitivity was lower in amygdala-predominant (6/14, 42.8%) and brainstem-predominant LBD (1/6, 16.7%), but early spread outside these regions (without meeting criteria for higher stage) was more common in αSyn-SAA-positive cases (6/7, 85.7%) than negative (2/13, 15.4%).DiscussionIn this behavioral neurology cohort, αSyn-SAA had excellent diagnostic performance for cortical LBD. In amygdala- and brainstem-predominant cases, sensitivity was lower, but positivity was associated with anatomical spread, suggesting αSyn-SAA detects early LBD progression in these cohorts.HighlightsA cerebrospinal fluid alpha-synuclein assay detects cortical LBD with high sensitivity/specificity. Positivity in prodromal stages of LBD was associated with early cortical spread. The assay provides precision diagnosis of LBD that could support clinical trials. The assay can also identify LBD co-pathology, which may impact treatment responses.
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- 2024
3. BepiColombo observations of cold oxygen and carbon ions in the flank of the induced magnetosphere of Venus
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Hadid, L. Z., Delcourt, D., Saito, Y., Fränz, M., Yokota, S., Fiethe, B., Verdeil, C., Katra, B., Leblanc, F., Fischer, H., Persson, M., Aizawa, S., André, N., Harada, Y., Fedorov, A., Fontaine, D., Krupp, N., Michalik, H., Berthelier, J-J., Krüger, H., Murakami, G., Matsuda, S., Heyner, D., Auster, H.-U., Richter, I., Mieth, J. Z. D., Schmid, D., and Fischer, D.
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- 2024
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4. Präklinische Post-Cardiac-Arrest-Sedierung und -Behandlung in der Bundesrepublik Deutschland – eine webbasierte Umfrage unter notärztlichem Personal
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Jansen, G., Latka, E., Deicke, M., Fischer, D., Gretenkort, P., Hoyer, A., Keller, Y., Kobiella, A., Ristau, P., Seewald, S., Strickmann, B., Thies, K. C., Johanning, K., and Tiesmeier, J.
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- 2024
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5. A pump-probe experiment in cw-mode on ionization of Rydberg atoms
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Romans, K. L., De Silva, A. H. N. C., Acharya, B. P., Foster, K., Russ, O., and Fischer, D.
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Physics - Atomic Physics - Abstract
Rydberg atoms are in the focus of intense research due to the peculiar properties which make them interesting candidates for quantum optics and quantum information applications. In this work we study the ionization of Rydberg atoms due to their interaction with a trapping laser field, and a reaction microscope is used to measure photoelectron angular and energy distributions. Reaction microscopes are excellent tools when brandished against atomic photoionization processes involving pulsed lasers; the timing tied to each pulse is crucial in solving the subsequent equations of motion for the atomic fragments in the spectrometer field. However, when used in pump-probe schemes, which rely on continuous wave probe lasers, vital information linked to the time of flight is lost. This study reports on a method in which the standard ReMi technique is extended in time through coincidence measurements. This is then applied to the photoionization of $^6$Li atoms initially prepared in optically pumped $2^{2}S_{1/2}$ and $2^{2}P_{3/2}$ states. Multi-photon excitation from a tunable femtosecond laser is exploited to produce Rydberg atoms inside an infrared optical dipole trap; the structure and dynamics of the subsequent cascade back towards ground is evaluated., Comment: 11 pages, 10 figures
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- 2023
6. A Precision Medicine Approach to Dementia Care: Syndrome, Etiology, and Copathology.
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Fischer, D Luke and Seeley, William W
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Health Services and Systems ,Health Sciences ,Brain Disorders ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Neurodegenerative ,Aging ,Acquired Cognitive Impairment ,Neurosciences ,Clinical Research ,Precision Medicine ,Dementia ,Alzheimer's Disease ,4.2 Evaluation of markers and technologies ,7.3 Management and decision making ,8.1 Organisation and delivery of services ,Neurological ,Good Health and Well Being ,Neurology & Neurosurgery - Abstract
Recognizing multiple neuropathological entities in people with dementia improves understanding of diagnosis, prognosis, and expected outcomes from therapies. Care for the individual with dementia includes the evaluation and management of diseases associated with the aged brain, most commonly neurodegeneration and vascular brain injury (VBI). Terminology has evolved to keep pace with diagnostic, prognostic, and therapeutic advances, and autopsy studies have shown that multiple comorbid neuropathological entities are the rule, not the exception, especially in older individuals. With the advent of disease-modifying therapies, delivering dementia care requires an encompassing framework that allows clinicians to consider all of an individual's underlying diseases and their contributions to symptom burden. A diagnostic approach, common co-occurring pathologies, and implications for current and future clinical care are reviewed.
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- 2023
7. The HD 260655 system: Two rocky worlds transiting a bright M dwarf at 10 pc
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Luque, R., Fulton, B. J., Kunimoto, M., Amado, P. J., Gorrini, P., Dreizler, S., Hellier, C., Henry, G. W., Molaverdikhani, K., Morello, G., Peña-Moñino, L., Pérez-Torres, M., Pozuelos, F. J., Shan, Y., Anglada-Escudé, G., Béjar, V. J. S., Bergond, G., Boyle, A. W., Caballero, J. A., Charbonneau, D., Ciardi, D. R., Dufoer, S., Espinoza, N., Everett, M., Fischer, D., Hatzes, A. P., Henning, Th., Hesse, K., Howard, A., Howell, S. B., Isaacson, H., Jeffers, S. V., Jenkins, J. M., Kane, S. R., Kemmer, J., Khalafinejad, S., Kidwell Jr., R. C., Kossakowski, D., Latham, D. W., Lillo-Box, J., Lissauer, J. J., Montes, D., Orell-Miquel, J., Pallé, E., Pollacco, D., Quirrenbach, A., Reffert, S., Reiners, A., Ribas, I., Ricker, G. R., Rogers, L. A., Sanz-Forcada, J., Schlecker, M., Schweitzer, A., Seager, S., Shporer, A., Stassun, K. G., Stock, S., Tal-Or, L., Ting, E. B., Trifonov, T., Vanaverbeke, S., Vanderspek, R., Villaseñor, J., Winn, J. N., Winters, J. G., and Osorio, M. R. Zapatero
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Astrophysics - Earth and Planetary Astrophysics ,Physics - Space Physics - Abstract
We report the discovery of a multi-planetary system transiting the M0 V dwarf HD 260655 (GJ 239, TOI-4599). The system consists of at least two transiting planets, namely HD 260655 b, with a period of 2.77 d, a radius of R$_b$ = 1.240$\pm$0.023 R$_\oplus$, a mass of M$_b$ = 2.14$\pm$0.34 M$_\oplus$, and a bulk density of $\rho_b$ = 6.2$\pm$1.0 g cm$^{-3}$, and HD 260655 c, with a period of 5.71 d, a radius of R$_c$ = 1.533$^{+0.051}_{-0.046}$ R$_\oplus$, a mass of M$_c$ = 3.09$\pm$0.48 M$_\oplus$, and a bulk density of $\rho_c$ = 4.7$^{+0.9}_{-0.8}$ g cm$^{-3}$. The planets were detected in transit by the TESS mission and confirmed independently with archival and new precise radial velocities obtained with the HIRES and CARMENES instruments since 1998 and 2016, respectively. At a distance of 10 pc, HD 260655 becomes the fourth closest known multi-transiting planet system after HD 219134, LTT 1445 A, and AU Mic. Due to the apparent brightness of the host star (J = 6.7 mag), both planets are among the most suitable rocky worlds known today for atmospheric studies with the JWST, both in transmission and emission., Comment: 24 pages, 17 figures. Accepted for publication in A&A
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- 2022
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8. Two-path interference in the resonance-enhanced few-photon ionization of atoms
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Acharya, B. P., Dubey, S., Romans, K. L., De Silva, A. H. N. C., Foster, K., Russ, O., Bartschat, K., Douguet, N., and Fischer, D.
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Physics - Atomic Physics - Abstract
We investigate the resonance-enhanced few-photon ionization of atomic lithium by linearly polarized light whose frequency is tuned near the 2s-2p transition. Considering the direction of light polarization orthogonal to the quantization axis, the process can be viewed as an atomic "double-slit experiment" where the 2p states with magnetic quantum numbers m_l=+-1 act as the slits. In our experiment, we can virtually close one of the two slits by preparing lithium in one of the two circularly polarized 2p states before subjecting it to the ionizing radiation. This allows us to extract the interference term between the two pathways and obtain complex phase information on the final state. The experimental results show very good agreement with numerical solutions of the time-dependent Schroedinger equation. The validity of the two-slit model is also analyzed theoretically using a time-dependent perturbative approach.
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- 2022
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9. Negative pressure wound therapy in burns: a prospective, randomized-controlled trial
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Tapking, C., Endlein, J., Warszawski, J., Kotsougiani-Fischer, D., Gazyakan, E., Hundeshagen, G., Hirche, C., Trofimenko, D., Burkard, T., Kneser, U., and Fischer, S.
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- 2024
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10. Magnetic Dichroism in Few-Photon Ionization of Polarized Atoms
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Acharya, B. P., Dodson, M., Dubey, S., Romans, K. L., De Silva, A. H. N. C., Foster, K., Russ, O., Bartschat, K., Douguet, N., and Fischer, D.
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Physics - Atomic Physics - Abstract
We consider few-photon ionization of atomic lithium by linearly polarized femtosecond laser pulses, and demonstrate that asymmetries of the electron angular distribution can occur for initially polarized (2p, m=+1) target atoms. The dependence of the photoelectron emission angle relative to the electric field direction is investigated at different laser intensities and wavelengths. The experimental spectra show excellent agreement with numerical solutions of the time-dependent Schroedinger equation. In the perturbative picture, the angular shift is traced back to interferences between partial waves with mean magnetic quantum number
$\ne$0. This observation allows us to obtain quantum mechanical information on the electronic final state., Comment: 7 pages, 4 figures - Published
- 2021
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11. Microplastic-antifouling paint particle contamination alters microbial communities in surrounding marine sediment
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Tagg, A.S., Sperlea, T., Hassenrück, C., Kreikemeyer, B., Fischer, D., and Labrenz, M.
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- 2024
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12. The obliquity and atmosphere of the ultra-hot Jupiter TOI-1431b (MASCARA-5b): A misaligned orbit and no signs of atomic ormolecular absorptions
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Stangret, M., Pallé, E., Casasayas-Barris, N., Oshagh, M., Bello-Arufe, A., Luque, R., Nascimbeni, V., Yan, F., Orell-Miquel, J., Sicilia, D., Malavolta, L., Addison, B. C., Buchhave, L. A., Bonomo, A. S., Borsa, F., Cabot, S. H. C., Cecconi, M., Fischer, D. A., Harutyunyan, A., Mendonça, J. M., Nowak, G., Parviainen, H., Sozzetti, A., and Tronsgaard, R.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Ultra-hot Jupiters are defined as giant planets with equilibrium temperatures larger than 2000 K. Most of them are found orbiting bright A-F type stars, making them extremely suitable objects to study their atmospheres using high-resolution spectroscopy. Recent studies show a variety of atoms and molecules detected in the atmospheres of this type of planets. Here we present our analysis of the newly discovered ultra-hot Jupiter TOI-1431b/MASCARA-5b, using two transit observations with the HARPS-N spectrograph and one transit observation with the EXPRES spectrograph. Analysis of the Rossiter-McLaughlin effect shows that the planet is in a polar orbit, with a projected obliquity $ \lambda = -155^{+20}_{-10}$ degrees. Combining the nights and applying both cross-correlation methods and transmission spectroscopy, we find no evidences of CaI, FeI, FeII, MgI, NaI, VI, TiO, VO or H$\alpha$ in the atmosphere of the planet. Our most likely explanation for the lack of atmospheric features is the large surface gravity of the planet., Comment: Accepted for publication in A&A (14 pages, 13 figures)
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- 2021
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13. Multi point analysis of coronal mass ejection flux ropes using combined data from Solar Orbiter, BepiColombo and Wind
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Weiss, A. J., Moestl, C., Davies, E. E., Amerstorfer, T., Bauer, M., Hinterreiter, J., Reiss, M., Bailey, R. L., Horbury, T. S., O'Brien, H., Evans, V., Angelini, V., Heiner, D., Richter, I., Auster, H-U., Magnes, W., Fischer, D., and Baumjohann, W.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
The recent launch of Solar Orbiter and BepiColombo opened a brief window in which these two spacecraft were positioned in a constellation that allows for the detailed sampling of any Earth-directed CMEs. Fortunately, two such events occurred with in situ detections of an ICME by Solar Orbiter on the 19th of April and the 28th of May 2020. These two events were subsequently also observed in situ by BepiColombo and Wind around a day later. We attempt to reconstruct the observed in situ magnetic field measurements for all three spacecraft simultaneously using an empirical magnetic flux rope model. This allows us to test the validity of our flux rope model on a larger and more global scale and allows for cross-validation of the analysis with different spacecraft combinations. Finally, we can also compare the results from the in situ modeling to remote observations obtained from the STEREO-A heliospheric imagers. We make use of the 3D coronal rope ejection model in order to simulate the ICME evolution. We adapt a previously developed ABC-SMC fitting algorithm for the application to multi point scenarios. We show that we are able to generally reconstruct the flux ropes signatures at three different spacecraft positions simultaneously using our model in combination with the flux rope fitting algorithm. For the well-behaved 19th of April ICME our approach works very well. The 28th of May ICME, on the other hand, shows the limitations of our approach. Unfortunately, the usage of multi-point observations for these events does not appear to solve inherent issues, such as the estimation of the magnetic field twist or flux rope aspect-ratios due to the specific constellation of the spacecraft positions. As our general approach can be used for any fast forward simulation-based model we give a blueprint for future studies using more advanced ICME models., Comment: 11 pages, 7 figures
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- 2021
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14. Circular Dichroism in Atomic Resonance-Enhanced Few-Photon Ionization
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De Silva, A. H. N. C., Moon, T., Romans, K. L., Acharya, B. P., Dubey, S., Foster, K., Russ, O., Rischbieter, C., Douguet, N., Bartschat, K., and Fischer, D.
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Physics - Atomic Physics - Abstract
We investigate few-photon ionization of lithium atoms prepared in the polarized 2$p$($m_\ell=\!+1$) state when subjected to femtosecond light pulses with left- or right-handed circular polarization at wavelengths between 665 nm and 920 nm. We consider whether ionization proceeds more favorably for the electric field co- or counter-rotating with the initial electronic current density. Strong asymmetries are found and quantitatively analyzed in terms of "circular dichroism" ($CD$). While the intensity dependence of the measured $CD$ values is rather weak throughout the investigated regime, a very strong sensitivity on the center wavelength of the incoming radiation is observed. While the co-rotating situation overall prevails, the counter-rotating geometry is strongly favored around 800 nm due to the 2$p$-3$s$ resonant transition, which can only be driven by counter-rotating fields. The observed features provide insights into the helicity dependence of light-atom interactions, and on the possible control of electron emission in atomic few-photon ionization by polarization-selective resonance enhancement.
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- 2021
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15. In situ multi-spacecraft and remote imaging observations of the first CME detected by Solar Orbiter and BepiColombo
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Davies, E. E., Möstl, C., Owens, M. J., Weiss, A. J., Amerstorfer, T., Hinterreiter, J., Bauer, M., Bailey, R. L., Reiss, M. A., Forsyth, R. J., Horbury, T. S., O'Brien, H., Evans, V., Angelini, V., Heyner, D., Richter, I., Auster, H-U., Magnes, W., Baumjohann, W., Fischer, D., Barnes, D., Davies, J. A., and Harrison, R. A.
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Physics - Space Physics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
On 2020 April 19 a coronal mass ejection (CME) was detected in situ by Solar Orbiter at a heliocentric distance of about 0.8 AU. The CME was later observed in situ on April 20th by the Wind and BepiColombo spacecraft whilst BepiColombo was located very close to Earth. This CME presents a good opportunity for a triple radial alignment study, as the spacecraft were separated by less than 5$^\circ$ in longitude. The source of the CME, which was launched on April 15th, was an almost entirely isolated streamer blowout. STEREO-A observed the event remotely from -75.1$^\circ$ longitude, which is an exceptionally well suited viewpoint for heliospheric imaging of an Earth directed CME. The configuration of the four spacecraft has provided an exceptionally clean link between remote imaging and in situ observations of the CME. We have used the in situ observations of the CME at Solar Orbiter, Wind, and BepiColombo, and the remote observations of the CME at STEREO-A in combination with flux rope models to determine the global shape of the CME and its evolution as it propagated through the inner heliosphere. A clear flattening of the CME cross-section has been observed by STEREO-A, and further confirmed by comparing profiles of the flux rope models to the in situ data, where the distorted flux rope cross-section qualitatively agrees most with in situ observations of the magnetic field at Solar Orbiter. Comparing in situ observations of the magnetic field between spacecraft, we find that the dependence of the maximum (mean) magnetic field strength decreases with heliocentric distance as $r^{-1.24 \pm 0.50}$ ($r^{-1.12 \pm 0.14}$), in disagreement with previous studies. Further assessment of the axial and poloidal magnetic field strength dependencies suggests that the expansion of the CME is likely neither self-similar nor cylindrically symmetric.
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- 2020
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16. Excalibur: A Non-Parametric, Hierarchical Wavelength-Calibration Method for a Precision Spectrograph
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Zhao, L. L., Hogg, D. W., Bedell, M., and Fischer, D. A.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
Excalibur is a non-parametric, hierarchical framework for precision wavelength-calibration of spectrographs. It is designed with the needs of extreme-precision radial velocity (EPRV) in mind, which require that instruments be calibrated or stabilized to better than $10^{-4}$ pixels. Instruments vary along only a few dominant degrees of freedom, especially EPRV instruments that feature highly stabilized optical systems and detectors. Excalibur takes advantage of this property by using all calibration data to construct a low-dimensional representation of all accessible calibration states for an instrument. Excalibur also takes advantage of laser frequency combs or etalons, which generate a dense set of stable calibration points. This density permits the use of a non-parametric wavelength solution that can adapt to any instrument or detector oddities better than parametric models, such as a polynomial. We demonstrate the success of this method with data from the EXtreme PREcision Spectrograph (EXPRES), which uses a laser frequency comb. When wavelengths are assigned to laser comb lines using excalibur, the RMS of the residuals is about five times lower than wavelengths assigned using polynomial fits to individual exposures. Radial-velocity measurements of HD 34411 showed a reduction in RMS scatter over a 10-month time baseline from $1.17$ to $1.05\, m\,s^{-1}$., Comment: 16 pages, 10 figures, presented here following first referee report
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- 2020
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17. Using circular dichroism to control energy transfer in multi-photon ionization
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De Silva, A. H. N. C., Atri-Schuller, D., Dubey, S., Acharya, B. P., Romans, K. L., Foster, K., Russ, O., Compton, K., Rischbieter, C., Douguet, N., Bartschat, K., and Fischer, D.
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Physics - Atomic Physics - Abstract
Chirality causes symmetry breaks in a large variety of natural phenomena ranging from particle physics to biochemistry. We investigate one of the simplest conceivable chiral systems, a laser-excited, oriented, effective one-electron Li target. Prepared in a polarized p state with |m|=1 in an optical trap, the atoms are exposed to co- and counter-rotating circularly polarized femtosecond laser pulses. For a field frequency near the excitation energy of the oriented initial state, a strong circular dichroism is observed and the photoelectron energies are significantly affected by the helicity-dependent Autler-Townes splitting. Besides its fundamental relevance, this system is suited to create spin-polarized electron pulses with a reversible switch on a femtosecond timescale at an energy resolution of a few meV.
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- 2020
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18. Photo-ionization of polarized lithium atoms out of an all-optical atom trap: A complete experiment
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Thini, F., Romans, K. L., Acharya, B. P., de Silva, A. H. N. C., Compton, K., Foster, K., Rischbieter, C., Russ, C., Sharma, S., Dubey, S., and Fischer, D.
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Physics - Atomic Physics - Abstract
An all-optical, near-resonant laser atom trap is used to prepare an electronically excited and polarized gas target at mK-temperature for complete photo-ionization studies. As a proof-of-principal experiment, lithium atoms in the 2$^2$P$_{3/2}$($m_l$=+1) state are ionized by a 266 nm laser source, and emitted electrons and Li$^+$ ions are momentum analyzed in a COLTRIMS spectrometer. The excellent resolution achieved in the present experiment allows not only to extract the relative phase and amplitude of all partial waves contributing to the final state, it also enables to characterize the experiment regarding target and spectrometer properties. Photo-electron angular distributions are measured for five different laser polarizations and described in a one-electron approximation with excellent agreement.
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- 2019
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19. Characterization of art materials and degradation processes in the exterior wall paintings of the main church of Rila Monastery, Bulgaria
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Stamboliyska, B., Tapanov, S., Kovacheva, D., Atanasova-Vladimirova, S., Ranguelov, B., Yancheva, D., Velcheva, E., Stoyanov, S., Guncheva, M., Fischer, D., and Lederer, A.
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- 2023
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20. On the deviation from Maxwellian of the ion velocity distribution functions in the turbulent magnetosheath
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Perri, Silvia, Perrone, D., Yordanova, E., Sorriso-Valvo, L., Paterson, W. R., Gershman, D. J., Giles, B. L., Pollock, C. J., Dorelli, J. C., Avanov, L. A., Lavraud, B., Saito, Y., Nakamura, R., Fischer, D., Baumjohann, W., Plaschke, F., Narita, Y., Magnes, W., Russell, C. T., Strangeway, R. J., Contel, O. Le, Khotyaintsev, Y., and Valentini, F.
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Physics - Space Physics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The degree of deviation from the thermodynamic equilibrium in the ion velocity distribution functions (VDFs), measured by the Magnetospheric Multiscale (MMS) mission in the Earth's turbulent magnetosheath, is quantitatively investigated. Taking advantage of MMS ion data, having a resolution never reached before in space missions, and of the comparison with Vlasov-Maxwell simulations, this analysis aims at relating any deviation from Maxwellian equilibrium to typical plasma parameters. Correlations of the non-Maxwellian features with plasma quantities such as electric fields, ion temperature, current density and ion vorticity are very similar in both magnetosheath data and numerical experiments, and suggest that distortions in the ion VDFs occur close to (but not exactly at) peaks in current density and ion temperature. Similar results have also been found during a magnetopause crossing by MMS. This work could help clarifying the origin of distortion of the ion VDFs in space plasmas.
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- 2019
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21. Radiative absorption enhancements by black carbon controlled by particle-to-particle heterogeneity in composition.
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Fierce, Laura, Onasch, Timothy B, Cappa, Christopher D, Mazzoleni, Claudio, China, Swarup, Bhandari, Janarjan, Davidovits, Paul, Fischer, D Al, Helgestad, Taylor, Lambe, Andrew T, Sedlacek, Arthur J, Smith, Geoffrey D, and Wolff, Lindsay
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absorption enhancement ,aerosol mixing state ,black carbon ,direct radiative forcing - Abstract
Black carbon (BC) absorbs solar radiation, leading to a strong but uncertain warming effect on climate. A key challenge in modeling and quantifying BC's radiative effect on climate is predicting enhancements in light absorption that result from internal mixing between BC and other aerosol components. Modeling and laboratory studies show that BC, when mixed with other aerosol components, absorbs more strongly than pure, uncoated BC; however, some ambient observations suggest more variable and weaker absorption enhancement. We show that the lower-than-expected enhancements in ambient measurements result from a combination of two factors. First, the often used spherical, concentric core-shell approximation generally overestimates the absorption by BC. Second, and more importantly, inadequate consideration of heterogeneity in particle-to-particle composition engenders substantial overestimation in absorption by the total particle population, with greater heterogeneity associated with larger model-measurement differences. We show that accounting for these two effects-variability in per-particle composition and deviations from the core-shell approximation-reconciles absorption enhancement predictions with laboratory and field observations and resolves the apparent discrepancy. Furthermore, our consistent model framework provides a path forward for improving predictions of BC's radiative effect on climate.
- Published
- 2020
22. Attitude Control on GRACE Follow-On: Experiences from the First Years in Orbit
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Cossavella, F., Herman, J., Hoffmann, L., Fischer, D., Save, H., Schlepp, B., Usbeck, T., De Rosa, Sergio, Series Editor, Zheng, Yao, Series Editor, Popova, Elena, Series Editor, Cruzen, Craig, editor, Schmidhuber, Michael, editor, and Lee, Young H., editor
- Published
- 2022
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23. Home-Based Pulmonary Rehabilitation of COPD Individuals Using the Wearable Respeck Monitor
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Arvind, D. K., Georgescu, T., Bates, C. A., Fischer, D., Zhou, Q., Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin (Sherman), Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Ur Rehman, Masood, editor, and Zoha, Ahmed, editor
- Published
- 2022
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24. The Fluxgate-Searchcoil Merged (FSM) Magnetic Field Data Product for MMS
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Argall, M. R., Fischer, D., Contel, O. Le, Mirioni, L., Torbert, R. B., Dors, I., Chutter, M., Needell, J., Strangeway, R., Magnes, W., and Russell, C. T.
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Physics - Space Physics - Abstract
The Fluxgate-Searchcoil Merged (FSM) data product for the Magnetospheric Multiscale (MMS) mission is created by combining the level-2 science quality data from the fluxgate and searchcoil magnetometers into a single level-3 data product. The merging method involves noise floor and calibration parameters determined both on the pre- and post-flight. Here, we describe the statistical inter-calibration process as well as the merging filter.
- Published
- 2018
25. An all-optical atom trap as a target for MOTRIMS-like collision experiments
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Sharma, S., Acharya, B. P., De Silva, A. H. N. C., Parris, N. W., Ramsey, B. J., Romans, K. L., Dorn, A., and Fischer, D.
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Physics - Atomic Physics - Abstract
Momentum-resolved scattering experiments with laser-cooled atomic targets have been performed since almost two decades with MOTRIMS (Magneto-Optical Trap Recoil Ion Momentum Spectroscopy) setups. Compared to experiments with gas-jet targets, MOTRIMS features significantly lower target temperatures allowing for an excellent recoil ion momentum resolution. However, the coincident and momentum-resolved detection of electrons was long rendered impossible due to incompatible magnetic field requirements. Here we report on a novel experimental approach which is based on an all-optical $^6$Li atom trap that -- in contrast to magneto-optical traps -- does not require magnetic field gradients in the trapping region. Atom temperatures of about 2 mK and number densities up to 10$^9$ cm$^{-3}$ make this trap ideally suited for momentum-resolved electron-ion coincidence experiments. The overall configuration of the new trap is very similar to conventional magneto-optical traps. It mainly requires small modifications of laser beam geometries and polarization which makes it easily implementable in other existing MOTRIMS experiments., Comment: submitted to Phys. Rev. A
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- 2017
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26. Trends in pharmaceutical analysis and quality control by modern Raman spectroscopic techniques
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Silge, A., Weber, Karina, Cialla-May, D., Müller-Bötticher, L., Fischer, D., and Popp, J.
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- 2022
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27. Pequenos frutos na prevenção de doenças crônicas não-transmissíveis: uma revisão
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BERGMANN, A. R., primary, SIEBENEICHLER, T. J., additional, FISCHER, L. O., additional, FISCHER, D. L. O., additional, and GALLI, V., additional
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- 2022
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28. Electron scale structures and magnetic reconnection signatures in the turbulent magnetosheath
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Yordanova, E., Vörös, Z., Varsani, A., Graham, D. B., Norgren, C., Khotyaintsev, Yu. V., Vaivads, A., Eriksson, E., Nakamura, R., Lindqvist, P. -A., Marklund, G., Ergun, R. E., Magnes, W., Baumjohann, W., Fischer, D., Plaschke, F., Narita, Y., Russell, C. T., Strangeway, R. J., Contel, O. Le, Pollock, C., Torbert, R. B., Giles, B. J., Burch, J. L., Avanov, L. A., Dorelli, J. C., Gershman, D. J., Lavraud, W. R. Paterson B., and Saito, Y.
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Physics - Space Physics - Abstract
Collisionless space plasma turbulence can generate reconnecting thin current sheets as suggested by recent results of numerical magnetohydrodynamic simulations. The MMS mission provides the first serious opportunity to check if small ion-electron-scale reconnection, generated by turbulence, resembles the reconnection events frequently observed in the magnetotail or at the magnetopause. Here we investigate field and particle observations obtained by the MMS fleet in the turbulent terrestrial magnetosheath behind quasi-parallel bow shock geometry. We observe multiple small-scale current sheets during the event and present a detailed look of one of the detected structures. The emergence of thin current sheets can lead to electron scale structures where ions are demagnetized. Within the selected structure we see signatures of ion demagnetization, electron jets, electron heating and agyrotropy suggesting that MMS spacecraft observe reconnection at these scales.
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- 2017
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29. High-Resolution Momentum Imaging—From Stern’s Molecular Beam Method to the COLTRIMS Reaction Microscope
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Jahnke, T., Mergel, V., Jagutzki, O., Czasch, A., Ullmann, K., Ali, R., Frohne, V., Weber, T., Schmidt, L. P., Eckart, S., Schöffler, M., Schößler, S., Voss, S., Landers, A., Fischer, D., Schulz, M., Dorn, A., Spielberger, L., Moshammer, R., Olson, R., Prior, M., Dörner, R., Ullrich, J., Cocke, C. L., Schmidt-Böcking, H., Friedrich, Bretislav, editor, and Schmidt-Böcking, Horst, editor
- Published
- 2021
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30. Multispacecraft Observations of a Widespread Solar Energetic Particle Event on 2022 February 15–16
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Khoo, L. Y., primary, Sánchez-Cano, B., additional, Lee, C. O., additional, Rodríguez-García, L., additional, Kouloumvakos, A., additional, Palmerio, E., additional, Carcaboso, F., additional, Lario, D., additional, Dresing, N., additional, Cohen, C. M. S., additional, McComas, D. J., additional, Lynch, B. J., additional, Fraschetti, F., additional, Jebaraj, I. C., additional, Mitchell, J. G., additional, Nieves-Chinchilla, T., additional, Krupar, V., additional, Pacheco, D., additional, Giacalone, J., additional, Auster, H.-U., additional, Benkhoff, J., additional, Bonnin, X., additional, Christian, E. R., additional, Ehresmann, B., additional, Fedeli, A., additional, Fischer, D., additional, Heyner, D., additional, Holmström, M., additional, Leske, R. A., additional, Maksimovic, M., additional, Mieth, J. Z. D., additional, Oleynik, P., additional, Pinto, M., additional, Richter, I., additional, Rodríguez-Pacheco, J., additional, Schwadron, N. A., additional, Schmid, D., additional, Telloni, D., additional, Vecchio, A., additional, and Wiedenbeck, M. E., additional
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- 2024
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31. EXPRES: A Next Generation RV Spectrograph in the Search for Earth-like Worlds
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Jurgenson, C., Fischer, D., McCracken, T., Sawyer, D., Szymkowiak, A., Davis, A. B., Muller, G., and Santoro, F.
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The EXtreme PREcision Spectrograph (EXPRES) is an optical fiber fed echelle instrument being designed and built at the Yale Exoplanet Laboratory to be installed on the 4.3-meter Discovery Channel Telescope operated by Lowell Observatory. The primary science driver for EXPRES is to detect Earth-like worlds around Sun-like stars. With this in mind, we are designing the spectrograph to have an instrumental precision of 15 cm/s so that the on-sky measurement precision (that includes modeling for RV noise from the star) can reach to better than 30 cm/s. This goal places challenging requirements on every aspect of the instrument development, including optomechanical design, environmental control, image stabilization, wavelength calibration, and data analysis. In this paper we describe our error budget, and instrument optomechanical design., Comment: 20 pages, 20 figures, SPIE Astronomical Telescopes & Instrumentation proceedings paper
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- 2016
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32. Primary results from IMpassion131, a double-blind, placebo-controlled, randomised phase III trial of first-line paclitaxel with or without atezolizumab for unresectable locally advanced/metastatic triple-negative breast cancer
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Zhang, Q., Xu, B., Shao, Z., Wang, X., Geng, C., Yan, X., Tong, Z., Shen, K., Yin, Y., Sun, T., Yang, J., Feng, J., Yan, M., Wang, Y., Liu, Q., Zhang, S., De Laurentiis, M., Santoro, A., Guarneri, V., Colleoni, M., Natoli, C., Cortesi, L., Placido, S., Gianni, L., Ferrau, F., Livi, L., Zambelli, A., Del Mastro, L., Tonini, G., Montemurro, F., Bianchi, G., Pedersini, R., Prete, S., Allegrini, G., Naso, G., Vici, P., Loirat, D., Mailliez, A., Priou, F., Tredan, O., Dalenc, F., Perrin, C., Gligorov, J., Timar David, M., Dohollou, N., Teixeira, L., Brocard, F., Arnaud, A., Delaloge, S., Spano, J.-P., Mansi, L., Andrade, L., Damian, F., Pedrini, J., Aleixo, S., Hegg, R., Junior, R., Reinisch, M., Schmidt, M., Wenzel, C., Grischke, E.-M., Schneeweiss, A., Just, M., Harbeck, N., Schumacher, C., Peters, U., Fischer, D., Forstbauer, H., Liersch, R., Warner, E., Bouganim, N., Doyle, C., Price Hiller, J., Vandenberg, T., Pavic, M., Robinson, A., Roldan Urgoiti, G., Califaretti, N., Alacacioglu, A., Gumus, M., Yalcin, B., Cicin, I., Kose, F., Uygun, K., Kaplan, M., Cubukcu, E., Wardley, A., Harries, M., Miles, D., Doval, D., Gupta, S., Mohapatra, P., Chatterjee, S., Ghadyalpatil, N., Singhal, M., Nag, S., Agarwal, A., Wolf, I., Gal Yam, E., Yerushalmi, R., Peretz, T., Fried, G., Ben Baruch, N., Katz, D., Hamilton, E., Kayali, F., Brufsky, A., Telli, M., Wright, G., Oyola, R., Rakowski, T., Graff, S., Tjulandin, S., Semiglazov, V., Aparicio, A., Ruiz Borrego, M., Merino, L., Guerra Martinez, J., Lopez, E., Yamashita, T., Ohtani, S., Inoue, K., Ito, Y., Niikura, N., Nakayama, T., Sagara, Y., Yanagita, Y., Kamada, Y., Kaneko, K., Kaen, D., Nervo, A., Eniu, A., Schenker, M., Priester, P., Melichar, B., Zimovjanova, M., Sormova, P., Sufliarsky, J., Kakalejcik, M., Belbaraka, R., Errihani, H., Le Than, D., Pham, D., Aravantinos, G., Papadimitriou, C., Koumakis, G., Papandreou, C., Podolski, P., Tabane, K., André, F., Cameron, D., Barrios, C., Patel, S., Patre, M., Morales, L., Patel, S.L., Kaul, M., Barata, T., and O’Shaughnessy, J.
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- 2021
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33. Attitude Control on GRACE Follow-On: Experiences from the First Years in Orbit
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Cossavella, F., primary, Herman, J., additional, Hoffmann, L., additional, Fischer, D., additional, Save, H., additional, Schlepp, B., additional, and Usbeck, T., additional
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- 2022
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34. Global observations of magnetospheric high‐m poloidal waves during the 22 June 2015 magnetic storm
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Le, G, Chi, PJ, Strangeway, RJ, Russell, CT, Slavin, JA, Takahashi, K, Singer, HJ, Anderson, BJ, Bromund, K, Fischer, D, Kepko, EL, Magnes, W, Nakamura, R, Plaschke, F, and Torbert, RB
- Subjects
ULF waves ,field line resonances ,high‐m poloidal waves ,magnetic storm ,magnetospheric multiscale mission ,Meteorology & Atmospheric Sciences - Abstract
We report global observations of high-m poloidal waves during the recovery phase of the 22 June 2015 magnetic storm from a constellation of widely spaced satellites of five missions including Magnetospheric Multiscale (MMS), Van Allen Probes, Time History of Events and Macroscale Interactions during Substorm (THEMIS), Cluster, and Geostationary Operational Environmental Satellites (GOES). The combined observations demonstrate the global spatial extent of storm time poloidal waves. MMS observations confirm high azimuthal wave numbers (m ~ 100). Mode identification indicates the waves are associated with the second harmonic of field line resonances. The wave frequencies exhibit a decreasing trend as L increases, distinguishing them from the single-frequency global poloidal modes normally observed during quiet times. Detailed examination of the instantaneous frequency reveals discrete spatial structures with step-like frequency changes along L. Each discrete L shell has a steady wave frequency and spans about 1 RE , suggesting that there exist a discrete number of drift-bounce resonance regions across L shells during storm times.
- Published
- 2017
35. The Use of Semi-Absorbable Mesh and its Impact on Donor-Site Morbidity and Patient-Reported Outcomes in DIEP Flap Breast Reconstruction
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Siegwart, L. C., Sieber, L., Fischer, S., Diehm, Y., Hirche, C., Kneser, U., and Kotsougiani-Fischer, D.
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- 2021
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36. Simultaneous compression and speckle reduction of clinical breast and fetal ultrasound images using rate-fidelity optimized coding
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Nemirovsky-Rotman, S., Friedman, Z., Fischer, D., Chernihovsky, A., Sharbel, K., and Porat, M.
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- 2021
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37. Electron moments derived from the Mercury Electron Analyzer during the cruise phase of BepiColombo
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Rojo, M., Persson, M., Sauvaud, J. -a., Aizawa, S., Nicolaou, G., Penou, E., Barthe, A., Andre, N., Mazelle, C., Fedorov, A., Yokota, S., Saito, Y., Heyner, D., Richter, I., Auster, U., Schmid, D., Fischer, D., Horbury, T., Owen, C. J., Maksimovic, M., Khotyaintsev, Yuri V., Louarn, P., Murakami, G., Rojo, M., Persson, M., Sauvaud, J. -a., Aizawa, S., Nicolaou, G., Penou, E., Barthe, A., Andre, N., Mazelle, C., Fedorov, A., Yokota, S., Saito, Y., Heyner, D., Richter, I., Auster, U., Schmid, D., Fischer, D., Horbury, T., Owen, C. J., Maksimovic, M., Khotyaintsev, Yuri V., Louarn, P., and Murakami, G.
- Abstract
Aims. We derive electron density and temperature from observations obtained by the Mercury Electron Analyzer on board Mio during the cruise phase of BepiColombo while the spacecraft is in a stacked configuration. Methods. In order to remove the secondary electron emission contribution, we first fit the core electron population of the solar wind with a Maxwellian distribution. We then subtract the resulting distribution from the complete electron spectrum, and suppress the residual count rates observed at low energies. Hence, our corrected count rates consist of the sum of the fitted Maxwellian core electron population with a contribution at higher energies. We finally estimate the electron density and temperature from the corrected count rates using a classical integration method. We illustrate the results of our derivation for two case studies, including the second Venus flyby of BepiColombo when the Solar Orbiter spacecraft was located nearby, and for a statistical study using observations obtained to date for distances to the Sun ranging from 0.3 to 0.9 AU. Results. When compared either to measurements of Solar Orbiter or to measurements obtained by HELIOS and Parker Solar Probe, our method leads to a good estimation of the electron density and temperature. Hence, despite the strong limitations arising from the stacked configuration of BepiColombo during its cruise phase, we illustrate how we can retrieve reasonable estimates for the electron density and temperature for timescales from days down to several seconds.
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- 2024
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38. HAT-P-57b: A Short-Period Giant Planet Transiting A Bright Rapidly Rotating A8V Star Confirmed Via Doppler Tomography
- Author
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Hartman, J. D., Bakos, G. Á., Buchhave, L. A., Torres, G., Latham, D. W., Kovács, G., Bhatti, W., Csubry, Z., de Val-Borro, M., Penev, K., Huang, C. X., Béky, B., Bieryla, A., Quinn, S. N., Howard, A. W., Marcy, G. W., Johnson, J. A., Isaacson, H., Fischer, D. A., Noyes, R. W., Falco, E., Esquerdo, G. A., Knox, R. P., Hinz, P., Lázár, J., Papp, I., and Sári, P.
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
We present the discovery of HAT-P-57b, a P = 2.4653 day transiting planet around a V = 10.465 +- 0.029 mag, Teff = 7500 +- 250 K main sequence A8V star with a projected rotation velocity of v sin i = 102.1 +- 1.3 km s^-1. We measure the radius of the planet to be R = 1.413 +- 0.054 R_J and, based on RV observations, place a 95% confidence upper limit on its mass of M < 1.85 M_J . Based on theoretical stellar evolution models, the host star has a mass and radius of 1.47 +- 0.12 M_sun, and 1.500 +- 0.050 R_sun, respectively. Spectroscopic observations made with Keck-I/HIRES during a partial transit event show the Doppler shadow of HAT-P-57b moving across the average spectral line profile of HAT-P- 57, confirming the object as a planetary system. We use these observations, together with analytic formulae that we derive for the line profile distortions, to determine the projected angle between the spin axis of HAT-P-57 and the orbital axis of HAT-P-57b. The data permit two possible solutions, with -16.7 deg < lambda < 3.3 deg or 27.6 deg < lambda < 57.4 deg at 95% confidence, and with relative probabilities for the two modes of 26% and 74%, respectively. Adaptive optics imaging with MMT/Clio2 reveals an object located 2.7" from HAT-P-57 consisting of two point sources separated in turn from each other by 0.22". The H and L -band magnitudes of the companion stars are consistent with their being physically associated with HAT-P-57, in which case they are stars of mass 0.61 +- 0.10 M_sun and 0.53 +- 0.08 M_sun. HAT-P-57 is the most rapidly rotating star, and only the fourth main sequence A star, known to host a transiting planet., Comment: 18 pages, 14 figures, 5 tables, accepted for publication in AJ
- Published
- 2015
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39. Planet Hunters X. KIC 8462852 - Where's the Flux?
- Author
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Boyajian, T. S., LaCourse, D. M., Rappaport, S. A., Fabrycky, D., Fischer, D. A., Gandolfi, D., Kennedy, G. M., Korhonen, H., Liu, M. C., Moor, A., Olah, K., Vida, K., Wyatt, M. C., Best, W. M. J., Brewer, J., Ciesla, F., Csak, B., Deeg, H. J., Dupuy, T. J., Handler, G., Heng, K., Howell, S. B., Ishikawa, S. T., Kovacs, J., Kozakis, T., Kriskovics, L., Lehtinen, J., Lintott, C., Lynn, S., Nespral, D., Nikbakhsh, S., Schawinski, K., Schmitt, J. R., Smith, A. M., Szabo, Gy., Szabo, R., Viuho, J., Wang, J., Weiksnar, A., Bosch, M., Connors, J. L., Goodman, S., Green, G., Hoekstra, A. J., Jebson, T., Jek, K. J., Omohundro, M. R., Schwengeler, H. M., and Szewczyk, A.
- Subjects
Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
Over the duration of the Kepler mission, KIC8462852 was observed to undergo irregularly shaped, aperiodic dips in flux of up to $\sim 20$\%. The dipping activity can last for between 5 and 80 days. We characterize the object with high-resolution spectroscopy, spectral energy distribution fitting, radial velocity measurements, high-resolution imaging, and Fourier analyses of the Kepler light curve. We determine that KIC8462852 is a typical main-sequence F3 V star that exhibits no significant IR excess, and has no very close interacting companions. In this paper, we describe various scenarios to explain the dipping events observed in the Kepler light curve. We confirm that the dipping signals in the data are not caused by any instrumental or data processing artifact, and thus are astrophysical in origin. We construct scenario-independent constraints on the size and location of a body in the system that is needed to reproduce the observations. We deliberate over several assorted stellar and circumstellar astrophysical scenarios, most of which have problems explaining the data in hand. By considering the observational constraints on dust clumps in orbit around a normal main-sequence star, we conclude that the scenario most consistent with the data in hand is the passage of a family of exocomet or planetesimal fragments, all of which are associated with a single previous break-up event, possibly caused by tidal disruption or thermal processing. The minimum total mass associated with these fragments likely exceeds $10^{-6}$~\mearth, corresponding to an original rocky body of $>100$~km in diameter. We discuss the necessity of future observations to help interpret the system., Comment: Accepted for publication in MNRAS. 17 pages, 13 figures
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- 2015
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40. Microcalorimeter Spectroscopy at High Pulse Rates: a Multi-Pulse Fitting Technique
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Fowler, J. W., Alpert, B. K., Doriese, W. B., Fischer, D. A., Jaye, C., Joe, Y. I., O'Neil, G. C., Swetz, D. S., and Ullom, J. N.
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Transition edge sensor microcalorimeters can measure x-ray and gamma-ray energies with very high energy resolution and high photon-collection efficiency. For this technology to reach its full potential in future x-ray observatories, each sensor must be able to measure hundreds or even thousands of photon energies per second. Current "optimal filtering" approaches to achieve the best possible energy resolution work only for photons well isolated in time, a requirement in direct conflict with the need for high-rate measurements. We describe a new analysis procedure to allow fitting for the pulse height of all photons even in the presence of heavy pulse pile-up. In the limit of isolated pulses, the technique reduces to the standard optimal filtering with long records. We employ reasonable approximations to the noise covariance function in order to render multi-pulse fitting computationally viable even for very long data records. The technique is employed to analyze x-ray emission spectra at 600 eV and 6 keV at rates up to 250 counts per second in microcalorimeters having exponential signal decay times of approximately 1.2 ms., Comment: This version exactly matches the submission to journal
- Published
- 2015
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41. KOI-3158: The oldest known system of terrestrial-size planets
- Author
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Campante, T. L., Barclay, T., Swift, J. J., Huber, D., Adibekyan, V. Zh., Cochran, W., Burke, C. J., Isaacson, H., Quintana, E. V., Davies, G. R., Aguirre, V. Silva, Ragozzine, D., Riddle, R., Baranec, C., Basu, S., Chaplin, W. J., Christensen-Dalsgaard, J., Metcalfe, T. S., Bedding, T. R., Handberg, R., Stello, D., Brewer, J. M., Hekker, S., Karoff, C., Kolbl, R., Law, N. M., Lundkvist, M., Miglio, A., Rowe, J. F., Santos, N. C., Van Laerhoven, C., Arentoft, T., Elsworth, Y. P., Fischer, D. A., Kawaler, S. D., Kjeldsen, H., Lund, M. N., Marcy, G. W., Sousa, S. G., Sozzetti, A., and White, T. R.
- Subjects
Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The first discoveries of exoplanets around Sun-like stars have fueled efforts to find ever smaller worlds evocative of Earth and other terrestrial planets in the Solar System. While gas-giant planets appear to form preferentially around metal-rich stars, small planets (with radii less than four Earth radii) can form under a wide range of metallicities. This implies that small, including Earth-size, planets may have readily formed at earlier epochs in the Universe's history when metals were far less abundant. We report Kepler spacecraft observations of KOI-3158, a metal-poor Sun-like star from the old population of the Galactic thick disk, which hosts five planets with sizes between Mercury and Venus. We used asteroseismology to directly measure a precise age of 11.2+/-1.0 Gyr for the host star, indicating that KOI-3158 formed when the Universe was less than 20% of its current age and making it the oldest known system of terrestrial-size planets. We thus show that Earth-size planets have formed throughout most of the Universe's 13.8-billion-year history, providing scope for the existence of ancient life in the Galaxy., Comment: Submitted to EPJ Web of Conferences, to appear in the Proceedings of the 3rd CoRoT Symposium, Kepler KASC7 joint meeting; 4 pages, 1 figure
- Published
- 2015
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42. An ancient extrasolar system with five sub-Earth-size planets
- Author
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Campante, T. L., Barclay, T., Swift, J. J., Huber, D., Adibekyan, V. Zh., Cochran, W., Burke, C. J., Isaacson, H., Quintana, E. V., Davies, G. R., Aguirre, V. Silva, Ragozzine, D., Riddle, R., Baranec, C., Basu, S., Chaplin, W. J., Christensen-Dalsgaard, J., Metcalfe, T. S., Bedding, T. R., Handberg, R., Stello, D., Brewer, J. M., Hekker, S., Karoff, C., Kolbl, R., Law, N. M., Lundkvist, M., Miglio, A., Rowe, J. F., Santos, N. C., Van Laerhoven, C., Arentoft, T., Elsworth, Y. P., Fischer, D. A., Kawaler, S. D., Kjeldsen, H., Lund, M. N., Marcy, G. W., Sousa, S. G., Sozzetti, A., and White, T. R.
- Subjects
Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The chemical composition of stars hosting small exoplanets (with radii less than four Earth radii) appears to be more diverse than that of gas-giant hosts, which tend to be metal-rich. This implies that small, including Earth-size, planets may have readily formed at earlier epochs in the Universe's history when metals were more scarce. We report Kepler spacecraft observations of Kepler-444, a metal-poor Sun-like star from the old population of the Galactic thick disk and the host to a compact system of five transiting planets with sizes between those of Mercury and Venus. We validate this system as a true five-planet system orbiting the target star and provide a detailed characterization of its planetary and orbital parameters based on an analysis of the transit photometry. Kepler-444 is the densest star with detected solar-like oscillations. We use asteroseismology to directly measure a precise age of 11.2+/-1.0 Gyr for the host star, indicating that Kepler-444 formed when the Universe was less than 20% of its current age and making it the oldest known system of terrestrial-size planets. We thus show that Earth-size planets have formed throughout most of the Universe's 13.8-billion-year history, leaving open the possibility for the existence of ancient life in the Galaxy. The age of Kepler-444 not only suggests that thick-disk stars were among the hosts to the first Galactic planets, but may also help to pinpoint the beginning of the era of planet formation., Comment: Accepted for publication in ApJ; 42 pages, 10 figures, 4 tables
- Published
- 2015
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43. A facility for cryogenic ion irradiation and in situ characterization of rare-earth barium copper oxide superconducting tapes.
- Author
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Devitre, A. R., Fischer, D. X., Woller, K. B., Clark, B. C., Short, M. P., Whyte, D. G., and Hartwig, Z. S.
- Subjects
- *
BARIUM oxide , *PARTICLE physics , *COPPER oxide , *BARIUM , *SUPERCONDUCTING magnets , *RARE earth oxides , *IRRADIATION - Abstract
Superconducting magnets based on Rare Earth Barium Copper Oxides (REBCO) offer transformative capabilities in the fields of fusion energy, high energy physics, and space exploration. A challenge shared by these applications is the limited lifetime of REBCO due to radiation damage sustained during operation. Here we present a new ion-beam facility that enables simultaneous cryogenic irradiation and in situ characterization of commercial REBCO tapes. The ion source provides spatially uniform fluxes up to 1018 protons/m2s with kinetic energies up to 3.4 MeV, in addition to helium and higher-Z species. Using this facility, we can induce uniform damage profiles in the first 10–20 µm of REBCO tapes with less than 0.25 appm of hydrogen implanted in REBCO after a dose of 1020 protons/m2. The tape can be held between 20 and 300 K with an accuracy of ±0.1 K and is connected to a four-point probe measuring the critical current, Ic, and critical temperature, Tc, before, during, and after irradiation with transport current ranging from 100 nA to 100 A, and a typical voltage noise less than 0.1 μV. These capabilities are presently used to study the effect of irradiation temperature on REBCO performance change during and after proton bombardment, to assess the possibility of Ic and Tc recovery after irradiation through thermal annealing, and to explore the instantaneous and recoverable suppression of Ic and Tc observed during irradiation. [ABSTRACT FROM AUTHOR]
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- 2024
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44. Characterisation of Breathing and Physical Activity Patterns in the General Population Using the Wearable Respeck Monitor
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Arvind, D. K., Fischer, D. J., Bates, C. A., Kinra, S., Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin (Sherman), Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Mucchi, Lorenzo, editor, Hämäläinen, Matti, editor, Jayousi, Sara, editor, and Morosi, Simone, editor
- Published
- 2019
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45. General care in the management of severe traumatic brain injury: Latin American consensus
- Author
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Godoy, D.A., Videtta, W., Santa Cruz, R., Silva, X., Aguilera-Rodríguez, S., Carreño-Rodríguez, J.N., Ciccioli, F., Piñero, G., Ciro, J.D., da Re-Gutiérrez, S., Domeniconi, G., Fischer, D., Hernández, O., Lacerda-Gallardo, Á., Mejía, J., Panhke, P., Romero, C., Lora, F.S., Soler-Morejón, C., Sufan, J.L., Montes, J.M., Fuenzalida, L.C., Parahnos, J.L., and Jibaja, M.
- Published
- 2020
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- View/download PDF
46. Lignes directrices canadiennes en immunothérapie orale : nouvelle méthodologie pour des recommandations axées sur le patient et reposant sur les évidences cliniques et les principes éthiques
- Author
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Bégin, P., Chan, E.S., Kim, H., Wagner, M., Cellier, M.S., Favron-Godbout, C., Abrams, E.M., Ben-Shoshan, M., Cameron, S.B., Carr, S., Fischer, D., Haynes, A., Kapur, S., Primeau, M.N., Upton, J., Vander Leek, T.K., and Goetghebeur, M.
- Published
- 2020
- Full Text
- View/download PDF
47. Semen analysis and successful artificial insemination in the St. Vincent amazon (Amazona guildingii)
- Author
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Fischer, D., Schneider, H., Meinecke-Tillmann, S., Wehrend, A., and Lierz, M.
- Published
- 2020
- Full Text
- View/download PDF
48. Central nervous signs, blindness and cerebral vermicosis in free-ranging peregrine falcons (Falco peregrinus) associated with aberrant larval migrations
- Author
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Fischer, D., Oberländer, B., Peters, M., Eley, N., Pantchev, N., Bangoura, B., and Lierz, M.
- Published
- 2020
- Full Text
- View/download PDF
49. The organization of sleep-wake patterns around daily schedules in college students
- Author
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Lu, S., primary, Stone, J., additional, Klerman, E., additional, McHill, A., additional, Barger, L., additional, Robbins, R., additional, Fischer, D., additional, Sano, A., additional, Czeisler, C., additional, Rajaratnam, S., additional, and Phillips, A., additional
- Published
- 2024
- Full Text
- View/download PDF
50. A comparative study of dipolarization fronts at MMS and Cluster
- Author
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Schmid, D, Nakamura, R, Volwerk, M, Plaschke, F, Narita, Y, Baumjohann, W, Magnes, W, Fischer, D, Eichelberger, HU, Torbert, RB, Russell, CT, Strangeway, RJ, Leinweber, HK, Le, G, Bromund, KR, Anderson, BJ, Slavin, JA, and Kepko, EL
- Subjects
Astronomical Sciences ,Physical Sciences ,Cluster ,MMS ,dipolarization front ,magnetotail ,Meteorology & Atmospheric Sciences - Abstract
We present a statistical study of dipolarization fronts (DFs), using magnetic field data from MMS and Cluster, at radial distances below 12 RE and 20 RE , respectively. Assuming that the DFs have a semicircular cross section and are propelled by the magnetic tension force, we used multispacecraft observations to determine the DF velocities. About three quarters of the DFs propagate earthward and about one quarter tailward. Generally, MMS is in a more dipolar magnetic field region and observes larger-amplitude DFs than Cluster. The major findings obtained in this study are as follows: (1) At MMS ∼57 % of the DFs move faster than 150 km/s, while at Cluster only ∼35 %, indicating a variable flux transport rate inside the flow-braking region. (2) Larger DF velocities correspond to higher Bz values directly ahead of the DFs. We interpret this as a snow plow-like phenomenon, resulting from a higher magnetic flux pileup ahead of DFs with higher velocities.
- Published
- 2016
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