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29 results on '"Gioulbasanis, Ioannis"'

1. Phase III study of the European Organisation for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire

Author

van Leeuwen, Marieke, Kieffer, Jacobien M., Young, Teresa E., Annunziata, Maria Antonietta, Arndt, Volker, Arraras, Juan Ignacio, Autran, Didier, Hani, Hira Bani, Chakrabarti, Manas, Chinot, Olivier, Cho, Juhee, da Costa Vieira, Rene Aloisio, Darlington, Anne-Sophie, Debruyne, Philip R., Dirven, Linda, Doege, Daniela, Eller, Yannick, Eichler, Martin, Fridriksdottir, Nanna, Gioulbasanis, Ioannis, Hammerlid, Eva, van Hemelrijck, Mieke, Hermann, Silke, Husson, Olga, Jefford, Michael, Johansen, Christoffer, Kjaer, Trille Kristina, Kontogianni, Meropi, Lagergren, Pernilla, Lidington, Emma, Lisy, Karolina, Morag, Ofir, Nordin, Andy, Al Omari, Amal S.H., Pace, Andrea, De Padova, Silvia, Petranovia, Duska, Pinto, Monica, Ramage, John, Rammant, Elke, Reijneveld, Jaap, Serpentini, Samantha, Sodergren, Sam, Vassiliou, Vassilios, Leeuw, Irma Verdonck-de, Vistad, Ingvild, Young, Teresa, Aaronson, Neil K., and van de Poll-Franse, Lonneke V.

Published
2023
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2. An international study of clinical, demographic and competence-related determinants of communication with professionals

Author

Arraras, Juan Ignacio, primary, Giesinger, Johannes, additional, Shamieh, Omar, additional, Bahar, Iqbal, additional, Koller, Michael, additional, Bredart, Anne, additional, Costantini, Anna, additional, Greimel, Eva, additional, Sztankay, Monika, additional, Wintner, Lisa M., additional, Sousa, Marina Carreiro, additional, Ishiki, Hiroto, additional, Kontogianni, Meropi, additional, Wolan, Maja, additional, Kikawa, Yuichiro, additional, Lanceley, Anne, additional, Gioulbasanis, Ioannis, additional, Harle, Amelie, additional, Zarandona, Uxue, additional, Kulis, Dagmara, additional, Gašpert, Tihana, additional, and Kuljanic, Karin, additional

Published
2024
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3. An international field study for the reliability and validity of the EORTC Communication Questionnaire EORTC QLQ-COMU26

Author

Arraras, Juan Ignacio, primary, Giesinger, Johannes, additional, Shamieh, Omar, additional, Bahar, Iqbal, additional, Koller, Michael, additional, Bredart, Anne, additional, Costantini, Anna, additional, Greimel, Eva, additional, Sztankay, Monika, additional, Wintner, Lisa M., additional, de Sousa, Marina Carreiro, additional, Ishiki, Hiroto, additional, Kontogianni, Meropi, additional, Wolan, Maja, additional, Kikawa, Yuichiro, additional, Lanceley, Anne, additional, Gioulbasanis, Ioannis, additional, Harle, Amelie, additional, Zarandona, Uxue, additional, Kulis, Dagmara, additional, and Kuljanic, Karin, additional

Published
2024
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4. Correction: Effect of body tissue composition on the outcome of patients with metastatic non-small cell lung cancer treated with PD-1/PD-L1 inhibitors

Author

Makrakis, Dimitrios, primary, Rounis, Konstantinos, additional, Tsigkas, Alexandros-Pantelis, additional, Georgiou, Alexandra, additional, Galanakis, Nikolaos, additional, Tsakonas, George, additional, Ekman, Simon, additional, Papadaki, Chara, additional, Monastirioti, Alexia, additional, Kontogianni, Meropi, additional, Gioulbasanis, Ioannis, additional, Mavroudis, i, additional, and Agelaki, Sofia, additional

Published
2023
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7. Effect of body tissue composition on the outcome of patients with metastatic non-small cell lung cancer treated with PD-1/PD-L1 inhibitors

Author

Makrakis, Dimitrios, primary, Rounis, Konstantinos, additional, Tsigkas, Alexandros-Pantelis, additional, Georgiou, Alexandra, additional, Galanakis, Nikolaos, additional, Tsakonas, George, additional, Ekman, Simon, additional, Papadaki, Chara, additional, Monastirioti, Alexia, additional, Kontogianni, Meropi, additional, Gioulbasanis, Ioannis, additional, Mavroudis, Dimitris, additional, and Agelaki, Sofia, additional

Published
2023
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10. Phase III study of the European Organisation for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire

Author

van Leeuwen, Marieke, Kieffer, Jacobien M., Young, Teresa E., Annunziata, Maria Antonietta, Arndt, Volker, Arraras, Juan Ignacio, Autran, Didier, Hani, Hira Bani, Chakrabarti, Manas, Chinot, Olivier, Cho, Juhee, da Costa Vieira, Rene Aloisio, Darlington, Anne-Sophie, Debruyne, Philip R., Dirven, Linda, Doege, Daniela, Eller, Yannick, Eichler, Martin, Friðriksdóttir, Nanna, de Giorgi, Ugo, Gioulbasanis, Ioannis, Hammerlid, Eva, van Hemelrijck, Mieke, Hermann, Silke, Husson, Olga, Jefford, Michael, Johansen, Christoffer, Johnson, Colin, Kjaer, Trille Kristina, Kontogianni, Meropi, Lagergren, Pernilla, Lidington, Emma, Lisy, Karolina, Morag, Ofir, Nordin, Andy, Al Omari, Amal S. H., Pace, Andrea, de Padova, Silvia, Petranoviæ, Duska, Pinto, Monica, Ramage, John, Rammant, Elke, Reijneveld, Jaap, Serpentini, Samantha, Sodergren, Sam, Vassiliou, Vassilios, Verdonck-de Leeuw, Irma, Vistad, Ingvild, Aaronson, Neil K., van de Poll-Franse, Lonneke V., Neurology, CCA - Cancer Treatment and quality of life, Otolaryngology / Head & Neck Surgery, APH - Mental Health, and APH - Personalized Medicine

Subjects
Oncology, Oncology (nursing), social sciences, humanities
Abstract

Purpose: The purpose of this study is to develop a European Organisation for Research and Treatment of Cancer Quality of Life Group (EORTC QLG) questionnaire that captures the full range of physical, mental, and social health-related quality of life (HRQOL) issues relevant to disease-free cancer survivors. In this phase III study, we pretested the provisional core questionnaire (QLQ-SURV111) and aimed to identify essential and optional scales. Methods: We pretested the QLQ-SURV111 in 492 cancer survivors from 17 countries with one of 11 cancer diagnoses. We applied the EORTC QLG decision rules and employed factor analysis and item response theory (IRT) analysis to assess and, where necessary, modify the hypothesized questionnaire scales. We calculated correlations between the survivorship scales and the QLQ-C30 summary score and carried out a Delphi survey among healthcare professionals, patient representatives, and cancer researchers to distinguish between essential and optional scales. Results: Fifty-four percent of the sample was male, mean age was 60 years, and, on average, time since completion of treatment was 3.8 years. Eleven items were excluded, resulting in the QLQ-SURV100, with 12 functional and 9 symptom scales, a symptom checklist, 4 single items, and 10 conditional items. The essential survivorship scales consist of 73 items. Conclusions: The QLQ-SURV100 has been developed to assess comprehensively the HRQOL of disease-free cancer survivors. It includes essential and optional scales and will be validated further in an international phase IV study. Implications for Cancer Survivors: The availability of this questionnaire will facilitate a standardized and robust assessment of the HRQOL of disease-free cancer survivors.

Published
2022

11. New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss

Author

Johns, Neil, Stretch, Cynthia, Tan, Benjamin H.L., Solheim, Tora S., Sørhaug, Sveinung, Stephens, Nathan A., Gioulbasanis, Ioannis, Skipworth, Richard J.E., Deans, D.A. Christopher, Vigano, Antonio, Ross, James A., Bathe, Oliver F., Tremblay, Michel L., Kaasa, Stein, Strasser, Florian, Gagnon, Bruno, Baracos, Vickie E., Damaraju, Sambasivarao, and Fearon, Kenneth C.H.

Published
2017
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12. Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi‐cohort analysis

Author

Martin, Lisa, primary, Muscaritoli, Maurizio, additional, Bourdel‐Marchasson, Isabelle, additional, Kubrak, Catherine, additional, Laird, Barry, additional, Gagnon, Bruno, additional, Chasen, Martin, additional, Gioulbasanis, Ioannis, additional, Wallengren, Ola, additional, Voss, Anne C., additional, Goldwasser, Francois, additional, Jagoe, R. Thomas, additional, Deans, Chris, additional, Bozzetti, Federico, additional, Strasser, Florian, additional, Thoresen, Lene, additional, Kazemi, Sean, additional, Baracos, Vickie, additional, and Senesse, Pierre, additional

Published
2021
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13. Cancer cachexia syndrome and clinical outcome in patients with metastatic non-small cell lung cancer treated with PD-1/PD-L1 inhibitors: results from a prospective, observational study

Author

Rounis, Konstantinos, primary, Makrakis, Dimitrios, additional, Tsigkas, Alexandros-Pantelis, additional, Georgiou, Alexandra, additional, Galanakis, Nikolaos, additional, Papadaki, Chara, additional, Monastirioti, Alexia, additional, Vamvakas, Lambros, additional, Kalbakis, Konstantinos, additional, Vardakis, Nikolaos, additional, Kontogianni, Meropi, additional, Gioulbasanis, Ioannis, additional, Mavroudis, Dimitrios, additional, and Agelaki, Sofia, additional

Published
2021
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14. Cancer-associated anorexia: Validity and performance overtime of different appetite tools among patients at their first cancer diagnosis

Author

Molfino, Alessio, primary, de van der Schueren, Marian A.E., additional, Sánchez-Lara, Karla, additional, Milke, Pilar, additional, Amabile, Maria Ida, additional, Imbimbo, Giovanni, additional, Di Lazzaro, Luca, additional, Cavuto, Silvio, additional, Ronzani, Giovanni, additional, Snegovoy, Anton, additional, Gioulbasanis, Ioannis, additional, and Laviano, Alessandro, additional

Published
2021
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15. Cancer patient satisfaction with health care professional communication: An international EORTC study.

Author

Arraras, Juan Ignacio, Giesinger, Johannes, Shamieh, Omar, Bahar, Iqbal, Koller, Michael, Bredart, Anne, Kuljanic, Karin, Costantini, Anna, Greimel, Eva, Sztankay, Monika, Wintner, Lisa M., Carreiro de Sousa, Marina, Ishiki, Hiroto, Kontogianni, Meropi, Wolan, Maja, Kikawa, Yuichiro, Lanceley, Anne, Gioulbasanis, Ioannis, Harle, Amelie, and Kuliś, Dagmara

Subjects
MEDICAL personnel, PATIENT satisfaction, COMMUNICATIVE disorders, INTERNATIONAL communication, ONCOLOGISTS, CANCER patient care, CANCER patients, PHYSICIANS' attitudes
Abstract

With regard to doctors' interpersonal skills and availability, patients with breast, colorectal and esophageal cancer were less satisfied than patients with lung and head and neck cancer in the multivariate analyses. 0--- ht 1 I N i , number of patients included in the study; I N i invited, number of patients invited per country; Attrition rate, percentage of patients per country who declined to participate. Keywords: cancer; communication; cross-cultural; oncology; psycho-oncology; satisfaction with care EN cancer communication cross-cultural oncology psycho-oncology satisfaction with care 541 547 7 03/11/22 20220301 NES 220301 Key points Patient satisfaction with communication with professionals has been found to be an important endpoint in cancer treatment, especially in studies evaluating routine Patient Reported Outcomes (PRO) monitoring. The greater SC among patients who receive treatment with palliative intention (chemo- and/or radiotherapy) suggests that more attention is given to communication with patients in non-curative treatment. [Extracted from the article]

Published
2022
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16. Cancer cachexia syndrome in the prediction of outcome in patients with metastatic non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs): Results from a single-institution, prospective, observational study.

Author

Mavroudis, Dimitrios, primary, Rounis, Konstantinos, additional, Makrakis, Dimitrios, additional, Georgiou, Alexandra, additional, Galanakis, Nikolaos, additional, Papadaki, Chara, additional, Vamvakas, Lampros, additional, Tsigkas, Alexandros-Pantelis, additional, Kontogianni, Meropi, additional, Gioulbasanis, Ioannis, additional, and Agelaki, Sofia, additional

Published
2020
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17. Cancer cachexia, sarcopenia and hand-GRIP strength (HGS) in the prediction of outcome in patients with metastatic non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs): A prospective, observational study.

Author

Agelaki, Sofia, primary, Rounis, Konstantinos, additional, Papadaki, Chara, additional, Monastirioti, Alexia A, additional, Vamvakas, Lampros, additional, Gioulbasanis, Ioannis, additional, Mavroudis, Dimitrios, additional, and Makrakis, Dimitris A, additional

Published
2019
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20. Cancer-Associated Malnutrition and CT-Defined Sarcopenia and Myosteatosis Are Endemic in Overweight and Obese Patients.

Author

Martin, Lisa, Gioulbasanis, Ioannis, Senesse, Pierre, and Baracos, Vickie E.

Subjects
SARCOPENIA, MALNUTRITION, BODY mass index, GASTROINTESTINAL system, HEAD & neck cancer, OBESITY complications, RESEARCH, RESEARCH methodology, EVALUATION research, MEDICAL cooperation, COMPARATIVE studies, RESEARCH funding, TUMORS, COMPUTED tomography, LONGITUDINAL method, DISEASE complications
Abstract

Background: Overweight/obese patients' large fat mass can mask the loss of skeletal muscle, which is associated with mortality in the oncology setting. We investigated the prevalence of computed tomography (CT)-defined sarcopenia and myosteatosis across different levels of nutrition risk assessed by the Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF). We also evaluated whether the PG-SGA SF, sarcopenia, and myosteatosis were prognostic of overall survival.Methods: This was a prospective, observational study. Consecutive patients with body mass index ≥25.0 kg/m2 with newly diagnosed head and neck cancer (any stage) or lung and gastrointestinal tract cancer (locally recurrent or metastatic) were screened at presentation to oncology clinics. Nutrition risk was assigned based on PG-SGA SF triage recommendations. Based on CT, patients were classified with sarcopenia and/or myosteatosis using published cutoffs. Survival analyses were conducted.Results: Patients (n=1157) were 63.6 ± 11.4 years, 64% male, and 61% had stage IV disease. Sarcopenia and myosteatosis were prevalent across PG-SGA SF nutrition risk categories (scores 0-1 [no risk; 36% sarcopenic; 44% myosteatotic], scores 2-3 [37%; 37%], scores 4-8 [40%; 41%], and scores ≥9 [high risk; 50%; 49%]). In multivariable survival analysis, PG-SGA SF scores ≥9 (hazard ratio [HR] 2.08, 95% confidence interval [CI] 1.66-2.60, P<0.001), sarcopenia (HR 1.25, 95% CI 1.06-1.46, P=0.006), and myosteatosis (HR 1.25, 95% CI 1.07-1.46, P<0.001) independently predicted reduced survival.Conclusion: CT-defined sarcopenia and myosteatosis are prevalent across different levels of nutrition risk in overweight/obese patients with cancer. Assessment of skeletal muscle using CT adds prognostic value to the PG-SGA SF. [ABSTRACT FROM AUTHOR]

Published
2020
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22. New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss

Author

Johns, Neil, Stretch, Cynthia, Tan, Benjamin H.L., Solheim, Tora S., Sørhaug, Sveinung, Stephens, Nathan A., Gioulbasanis, Ioannis, Skipworth, Richard J.E., Deans, D.A. Christopher, Vigano, Antonio, Ross, James A., Bathe, Oliver F., Tremblay, Michel L., Kaasa, Stein, Strasser, Florian, Gagnon, Bruno, Baracos, Vickie E., Damaraju, Sambasivarao, and Fearon, Kenneth C.H.

Subjects
Adult, Male, Cachexia, Genotype, Polymorphism, Single Nucleotide, Young Adult, Neoplasms, Weight Loss, Genetics, Humans, Muscle, Skeletal, Letters to the Editor, Letter to the Editor, Cancer, Aged, Retrospective Studies, Aged, 80 and over, Nucleotides, Original Articles, Middle Aged, Muscular Atrophy, Phenotype, Original Article, Female, Polymorphisms, Tomography, X-Ray Computed, Transcriptome
Abstract

BACKGROUND: Cachexia affects the majority with advanced cancer. Based on current demographic and clinical factors, it is not possible to predict who will develop cachexia or not. Such variation may, in part, be due to genotype. It has recently been proposed to extend the diagnostic criteria for cachexia to include a direct measure of low skeletal muscle index (LSMI) in addition to weight loss (WL). We aimed to explore our panel of candidate single nucleotide polymorphism (SNPs) for association with WL +/- computerized tomography-defined LSMI. We also explored whether the transcription in muscle of identified genes was altered according to such cachexia phenotype METHODS: A retrospective cohort study design was used. Analysis explored associations of candidate SNPs with WL (n = 1276) and WL + LSMI (n = 943). Human muscle transcriptome (n = 134) was analysed using an Agilent platform.RESULTS: Single nucleotide polymorphisms in the following genes showed association with WL alone: GCKR, LEPR, SELP, ACVR2B, TLR4, FOXO3, IGF1, CPN1, APOE, FOXO1, and GHRL. SNPs in LEPR, ACVR2B, TNF, and ACE were associated with concurrent WL + LSMI. There was concordance between muscle-specific expression for ACVR2B, FOXO1 and 3, LEPR, GCKR, and TLR4 genes and LSMI and/or WL (P CONCLUSIONS: The rs1799964 in the TNF gene and rs4291 in the ACE gene are new associations when the definition of cachexia is based on a combination of WL and LSMI. These findings focus attention on pro-inflammatory cytokines and the renin-angiotensin system as biomarkers/mediators of muscle wasting in cachexia.

Published
2016

24. New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss

Author

Johns, Neil, primary, Stretch, Cynthia, additional, Tan, Benjamin H.L., additional, Solheim, Tora S., additional, Sørhaug, Sveinung, additional, Stephens, Nathan A., additional, Gioulbasanis, Ioannis, additional, Skipworth, Richard J.E., additional, Deans, D.A. Christopher, additional, Vigano, Antonio, additional, Ross, James A., additional, Bathe, Oliver F., additional, Tremblay, Michel L., additional, Kaasa, Stein, additional, Strasser, Florian, additional, Gagnon, Bruno, additional, Baracos, Vickie E., additional, Damaraju, Sambasivarao, additional, and Fearon, Kenneth C.H., additional

Published
2016
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28. Diagnostic Criteria for the Classification of Cancer-Associated Weight Loss

Author

Martin, Lisa, primary, Senesse, Pierre, additional, Gioulbasanis, Ioannis, additional, Antoun, Sami, additional, Bozzetti, Federico, additional, Deans, Chris, additional, Strasser, Florian, additional, Thoresen, Lene, additional, Jagoe, R. Thomas, additional, Chasen, Martin, additional, Lundholm, Kent, additional, Bosaeus, Ingvar, additional, Fearon, Kenneth H., additional, and Baracos, Vickie E., additional

Published
2015
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