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2,314 results on '"Gogos A"'

1. Tailoring the Spectral and Directional Emissivity of Functionalized Laser Processed Surfaces

Author

Butler, Andrew, Reicks, Andrew, Alexander, Dennis, Gogos, George, Zuhlke, Craig A., and Argyropoulos, Christos

Subjects
Physics - Optics, Physics - Applied Physics
Abstract

Development of methods to control the directional and spectral characteristics of thermal radiation from metallic surfaces is a critical factor enabling many important thermal management applications. In this paper, we study the thermal emission properties of functionalized aluminum surfaces produced through femtosecond laser surface processing (FLSP). These types of surfaces have recently been found to exhibit near-unity broadband omnidirectional emissivity. However, their ultrabroadband absorption response includes visible and near-infrared (IR) radiation, in addition to the mid-IR range, which limits their use as daytime passive radiative cooling devices. Here, we present ways to solve this problem by demonstrating a new design that uses a dielectric Bragg visible light reflector to accurately control the thermal emission spectra of the FLSP surface with the goal of achieving high performance daytime radiative cooling operation. In addition, we propose other designs based on dielectric multilayer structures to further tailor and control the spectra and thermal emission angles of the FLSP surfaces leading to narrowband and broadband directional thermal radiation. The presented photonic engineering approach combined with FLSP structures will be beneficial to various emerging applications, such as radiative cooling, thermal sensing, and thermophotovoltaics.

Published
2024
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2. Nicotine consumption during the prodromal phase of schizophrenia – a review of the literature

Author

Gogos A, Skokou M, Ferentinou E, and Gourzis P

Subjects
tobacco, smoking, psychosis, ultra high risk, conversion, clinical high risk, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Athanasios Gogos,1,* Maria Skokou,2,* Eleni Ferentinou,1 Philippos Gourzis2 1School of Medicine, University of Patras, Rion, Patras, Greece; 2Department of Psychiatry, University Hospital of Patras, Rion, Patras, Greece*These authors contributed equally to this workCorrespondence: Philippos GourzisDepartment of Psychiatry, General University Hospital of Patras, School of Medicine, University of Patras, University Campus, Rio 26504, GreeceTel +30 2610 990559Fax +30 261 099 4534Email pgourzis@upatras.grAbstract: Recent research has fueled a debate concerning the role of nicotine in the emergence of schizophrenia. The three main hypotheses are: (a) the self-medication effect, (b) the causal relationship hypothesis, or (c) the shared diathesis hypothesis. To explore this role, the study of nicotine consumption during the initial prodromal phase of schizophrenia offers important opportunities. In the present work, 10 relevant studies are reviewed, out of 727 retrieved citations, in order to address questions regarding the prevalence of smoking in the prodromal period, the time of smoking initiation, existing patterns of tobacco use in relation with the escalation of prodromal symptoms into first psychotic episode, and potential differences in symptomatology between smokers and nonsmokers. Even though there was considerable heterogeneity among studies, relevant findings are discussed. Prevalence of nicotine use during the prodromal period was reported to be 16.6–46%. Tobacco use was found to be taken up most often before or during the prodromal period of schizophrenia. Even though a protective role of smoking has been reported by one study, other studies report an increased risk for psychosis, with hazard ratios 2.77 (95% CI: 2.34–3.43) and 2.21 (95% CI: 1.11–4.42) for female and male heavy smokers (11–20 and >20 cigarettes/day), respectively. In a different study, the risk of onset was associated with the progressive use of cannabis and tobacco prior to onset, particularly with rapid escalation to the highest levels of use. Also, nicotine use in ultra high risk (UHR) for developing psychosis subjects is associated with elevated cognitive performance, namely better processing speed, visual learning, and spatial working memory. As a conclusion, it appears that evidence accumulates supporting a possible etiologic role of smoking, in the emergence of schizophrenia along with diverse effects on patients’ symptomatology, already demonstrable at the prodromal phase. Future research employing better-defined criteria should further explore the patterns of use and effects of nicotine during the schizophrenia prodrome.Keywords: tobacco, smoking, psychosis, ultra high risk, conversion, clinical high risk

Published
2019

6. Unraveling the formation dynamics of metallic femtosecond laser induced periodic surface structures

Author

Khorashad, L. Khosravi, Reicks, A., Erickson, A., Shield, J. E., Alexander, D., Laraoui, A., Gogos, G., Zuhlke, C., and Argyropoulos, C.

Subjects
Physics - Optics
Abstract

Femtosecond laser surface processing (FLSP) is an emerging fabrication technique to efficiently control the surface morphology of many types of materials including metals. However, the theoretical understanding of the FLSP formation dynamics is not a trivial task, since it involves the interaction of various physical processes (electromagnetic, thermal, fluid dynamics) and remains relatively unexplored. In this work, we tackle this problem and present rigorous theoretical results relevant to low-fluence FLSP that accurately match the outcomes of an experimental campaign focused on the formation dynamics of laser induced periodic surface structures (LIPSS) on stainless steel. More specifically, the topology and maximum depth of LIPSS trenches are theoretically and experimentally investigated as a function of the number of laser pulses. Moreover, precise LIPSS morphology measurements are performed using atomic force microscopy (AFM). The proposed comprehensive simulation study is based on two-temperature model (TTM) non-equilibrium thermal simulations coupled with fluid dynamic computations to capture the melting metal phase occurring during FLSP. Our rigorous simulation results are found to be in excellent agreement with the AFM measurements. The presented theoretical framework to model FLSP under low-fluence femtosecond laser pulses will be beneficial to various emerging applications of LIPSS on metallic surfaces, such as cooling high-powered laser diodes and controlling the thermal emission or absorption of metals.

Published
2023
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8. Real-World Use and Treatment Outcomes of Ceftaroline Fosamil in Patients with Complicated Skin and Soft Tissue Infection: A Multinational Retrospective Study

Author

Ferry T, Gogos C, Soriano A, Blasi F, Ansari W, Kantecki M, Schweikert B, Luna G, and Bassetti M

Subjects
antibiotics, real-world evidence, efficacy, healthcare resource use, Infectious and parasitic diseases, RC109-216
Abstract

Tristan Ferry,1 Charalambos Gogos,2 Alex Soriano,3 Francesco Blasi,4,5 Wajeeha Ansari,6 Michal Kantecki,7 Bernd Schweikert,8 Gustavo Luna,9 Matteo Bassetti10 1Infectious Diseases Department, Croix-Rousse Hospital, Hospices Civils de Lyon, Lyon, France; 2Division of Infectious Diseases, Department of Internal Medicine, University of Patras, Patras, Greece; 3Infectious Diseases Department, Hospital Clínic de Barcelona, CIBERINF, CIBER in Infectious Diseases, Barcelona, Spain; 4Respiratory Unit and Cystic Fibrosis Center, Foundation IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy; 5Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; 6Pfizer Biopharmaceuticals Group, Pfizer Inc., New York, NY, USA; 7Global Medical Affairs, Pfizer International Operations, Pfizer, Paris, France; 8Health Economics and Epidemiology, ICON plc, Munich, Germany; 9Health Economics and Epidemiology, ICON plc, Stockholm, Sweden; 10Infectious Diseases, Clinica Malattie Infettive, Ospedale Policlinico IRCCS San Martino and University of Genoa, Genoa, ItalyCorrespondence: Wajeeha Ansari, Pfizer Inc., 66 Hudson Blvd E, New York, NY, 10001, USA, Email wajeeha.ansari@pfizer.comBackground: Ceftaroline fosamil is approved for the treatment of complicated skin and soft tissue infections (cSSTI) and community-acquired pneumonia (CAP); however, data on its real-world use and effectiveness in Europe and Latin America are currently limited. This retrospective observational study assessed ceftaroline fosamil use and treatment outcomes in adults hospitalized with cSSTI or CAP treated with ceftaroline fosamil in a usual care setting in Europe and Latin America. Results for patients with cSSTI are reported.Methods: Data from patients with cSSTI who received ≥ 4 consecutive intravenous ceftaroline fosamil doses up to May 31, 2019, were collected from sites in Brazil, Colombia, France, Greece, Italy, and Spain. Patient characteristics, clinical management, hospitalization information, microbiological diagnosis, and clinical responses were summarized descriptively. Healthcare resource use variables were evaluated by clinical response to ceftaroline fosamil.Results: Data for 132 patients were included (58.3% male; mean age 58.5 years). Most common lesions were cellulitis/fasciitis (62.1%), abscess (34.1%), and post-surgical wounds (19.7%). Pathogens most frequently identified were methicillin-resistant (18.2%) and methicillin-susceptible Staphylococcus aureus (17.4%). Median (range) ceftaroline fosamil treatment duration was 8 (2– 60) days (daily doses of 1200 [400– 2400] mg); 78 patients (59.1%) received monotherapy. In total, 75 (56.8%) patients had additional antibiotics after ceftaroline fosamil. Clinical response occurred in 118 (89.4%) patients. All-cause 30-day readmission occurred in 13 (9.8%) patients, and all-cause 30-day mortality in 7 (5.3%). Clinical response to ceftaroline was associated with > 25% shorter length of hospital and intensive care stay, and with ~40% lower hospital costs, versus non-responders.Conclusion: Ceftaroline fosamil was effective in treating adults with cSSTI and clinical response to ceftaroline fosamil was associated with reductions in healthcare resource use compared with non-responders, in Europe and Latin America.Clinicaltrials.gov Identifier: NCT04198571.Keywords: antibiotics, real-world evidence, efficacy, healthcare resource use

Published
2024

11. Urban thoracic trauma: diagnosis and initial treatment of non-cardiac injuries in adults

Author

Vasileios Leivaditis, Athanasios Papatriantafyllou, Ioanna Akrida, Michail Galanis, Emmanouil Dimopoulos, Anastasia Papaporfyriou, Benjamin Ehle, Efstratios Koletsis, Nikolaos Charokopos, George Pappas-Gogos, Francesk Mulita, Georgios-Ioannis Verras, Konstantinos Tasios, Vasiliki Garantzioti, Levan Tchabashvili, Manfred Dahm, and Konstantinos Grapatsas

Subjects
hematothorax, pneumthorax, tho-racic trauma, urban trauma, Medicine
Abstract

This comprehensive review aims to delineate the prevailing non-cardiac thoracic injuries occurring in urban environments following initial on-site treatment and subsequent admission to hospital emergency departments. Our study involved a rigorous search within the PubMed database, employing key phrases and their combinations, including "thoracic injury," "thoracic trauma," "haemothorax," "lung contusion," "traumatic pneumothorax," "rib fractures," and "flail chest." We focused on original research articles and reviews. Non-cardiac thoracic injuries exhibit a high prevalence, often affecting poly-trauma patients, and contributing to up to 35% of polytrauma-related fatalities. Furthermore, severe thoracic injuries can result in a substantial 5% mortality rate. This review provides insights into clinical entities such as lung contusion, traumatic haemothorax, pneumothorax, rib fractures, and sternal fractures. Thoracic injuries represent a frequent and significant clinical concern for emergency department physicians and thoracic surgeons, warranting thorough understanding and timely intervention.

Published
2024
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12. Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma

Author

Hervey-Jumper, Shawn L, Zhang, Yalan, Phillips, Joanna J, Morshed, Ramin A, Young, Jacob S, McCoy, Lucie, Lafontaine, Marisa, Luks, Tracy, Ammanuel, Simon, Kakaizada, Sofia, Egladyous, Andrew, Gogos, Andrew, Villanueva-Meyer, Javier, Shai, Anny, Warrier, Gayathri, Rice, Terri, Crane, Jason, Wrensch, Margaret, Wiencke, John K, Daras, Mariza, Bush, Nancy Ann Oberheim, Taylor, Jennie W, Butowski, Nicholas, Clarke, Jennifer, Chang, Susan, Chang, Edward, Aghi, Manish, Theodosopoulos, Philip, McDermott, Michael, Jakola, Asgeir S, Kavouridis, Vasileios K, Nawabi, Noah, Solheim, Ole, Smith, Timothy, Berger, Mitchel S, and Molinaro, Annette M

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Patient Safety, Neurosciences, Orphan Drug, Cancer, Brain Cancer, Brain Disorders, Clinical Research, Rare Diseases, Precision Medicine, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Humans, Oligodendroglioma, Retrospective Studies, Brain Neoplasms, Neurosurgical Procedures, Glioma, Astrocytoma, Treatment Outcome, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

PurposeIn patients with diffuse low-grade glioma (LGG), the extent of surgical tumor resection (EOR) has a controversial role, in part because a randomized clinical trial with different levels of EOR is not feasible.MethodsIn a 20-year retrospective cohort of 392 patients with IDH-mutant grade 2 glioma, we analyzed the combined effects of volumetric EOR and molecular and clinical factors on overall survival (OS) and progression-free survival by recursive partitioning analysis. The OS results were validated in two external cohorts (n = 365). Propensity score analysis of the combined cohorts (n = 757) was used to mimic a randomized clinical trial with varying levels of EOR.ResultsRecursive partitioning analysis identified three survival risk groups. Median OS was shortest in two subsets of patients with astrocytoma: those with postoperative tumor volume (TV) > 4.6 mL and those with preoperative TV > 43.1 mL and postoperative TV ≤ 4.6 mL. Intermediate OS was seen in patients with astrocytoma who had chemotherapy with preoperative TV ≤ 43.1 mL and postoperative TV ≤ 4.6 mL in addition to oligodendroglioma patients with either preoperative TV > 43.1 mL and residual TV ≤ 4.6 mL or postoperative residual volume > 4.6 mL. Longest OS was seen in astrocytoma patients with preoperative TV ≤ 43.1 mL and postoperative TV ≤ 4.6 mL who received no chemotherapy and oligodendroglioma patients with preoperative TV ≤ 43.1 mL and postoperative TV ≤ 4.6 mL. EOR ≥ 75% improved survival outcomes, as shown by propensity score analysis.ConclusionAcross both subtypes of LGG, EOR beginning at 75% improves OS while beginning at 80% improves progression-free survival. Nonetheless, maximal resection with preservation of neurological function remains the treatment goal. Our findings have implications for surgical strategies for LGGs, particularly oligodendroglioma.

Published
2023

15. SPRINT: Semantics for PerfoRmant and scalable INteroperability of multimodal Transport

Author

Sadeghi, Mersedeh, Buchniček, Petr, Carenini, Alessio, Corcho, Oscar, Gogos, Stefanos, Rossi, Matteo, and Santoro, Riccardo

Subjects
Computer Science - Software Engineering
Abstract

Interoperability is a long-standing challenge slowing down the digitalization of mobility systems and the provision of full mobility-as-a-service offerings. This paper presents early results achieved by the SPRINT project (Semantics for PerfoRmant and scalable INteroperability of multimodal Transport), an integral part of the Shift2Rail IP4 work programme, in meeting the challenge. It introduces the conceptual architecture and describes the demonstrator implementation of the Interoperability Framework (IF), a solution designed to support servitization in the mobility domain in two directions: From the Travel Application perspective, the IF provides semantically-consistent abstractions of distributed ICT resources offered by Service Provider Companies, insulating them from the "mechanics" of operating remotely over networks and across multiple communication protocols and/or data formats; from the Service Provider Companies perspective, the IF allows leveraging their native ICT computing environment and resources as elements of an end-to-end integrated intermodal mobility solution, insulating them from the specifics of the customer front-end applications.

Published
2022

19. The effect of estradiol add-back: a longitudinal MRI study in prostate cancer patients

Author

Orwa Dandash, James Allebone, Adam Mirabelli, Nicholas Russell, Mathis Grossmann, Andrea Gogos, and Richard A Kanaan

Subjects
prostate cancer, mri, androgen deprivation, estradiol, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

We investigated the effect of estradiol add-back therapy (EAT) on brain activation related to cognitive function and affect in addition to putative changes in gray and white matter volume in testosterone depleted participants with prostate cancer. We conducted a randomized controlled, double-blinded trial in which 40 patients received 0.9 mg of transdermal estradiol per day for 6 months or matched placebo. Anatomical MRI and three functional MRI (fMRI) scans were obtained for the emotion recognition task, verbal memory task, and visuospatial memory task. Activation in corresponding cognitive and affective brain networks was demonstrated for all tasks. Longitudinally, there was no difference in brain activation, reaction time, or accuracy in response to the fMRI tasks between the EAT group and placebo group at 6 months. In addition, there was no detectable change in whole-brain gray or white matter volume or in hippocampal volume between the two groups after 6 months. This study supports earlier findings that EAT does not improve verbal memory or affect and has no immediate effect on hippocampal volume in testosterone depleted patients with prostate cancer.

Published
2024
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20. 'When,' 'Where,' and 'How' of SARS-CoV-2 Infection Affects the Human Cardiovascular System: A Narrative Review

Author

Nicholas G. Kounis, Christos Gogos, Cesare de Gregorio, Ming-Yow Hung, Sophia N. Kounis, Efthymios P. Tsounis, Stelios F. Assimakopoulos, Soheila Pourmasumi, Virginia Mplani, George Servos, Periklis Dousdampanis, Panagiotis Plotas, Marina A. Michalaki, Grigorios Tsigkas, Gerasimos Grammatikopoulos, Dimitrios Velissaris, and Ioanna Koniar

Subjects
Medicine
Abstract

Coronavirus disease 2019 (COVID-19) is caused by the novel severe acute respiratory coronavirus-2 (SARS-CoV-2). Several explanations for the development of cardiovascular complications during and after acute COVID-19 infection have been hypothesized. The COVID-19 pandemic, caused by SARS-CoV-2, has emerged as one of the deadliest pandemics in modern history. The myocardial injury in COVID-19 patients has been associated with coronary spasm, microthrombi formation, plaque rupture, hypoxic injury, or cytokine storm, which have the same pathophysiology as the three clinical variants of Kounis syndrome. The angiotensin-converting enzyme 2 (ACE2), renin-aldosterone system (RAAS), and kinin-kallikrein system are the main proposed mechanisms contributing to cardiovascular complications with the COVID-19 infection. ACE receptors can be found in the heart, blood vessels, endothelium, lungs, intestines, testes, neurons, and other human body parts. SARS-CoV-2 directly invades the endothelial cells with ACE2 receptors and constitutes the main pathway through which the virus enters the endothelial cells. This causes angiotensin II accumulation downregulation of the ACE2 receptors, resulting in prothrombotic effects, such as hemostatic imbalance via activation of the coagulation cascade, impaired fibrinolysis, thrombin generation, vasoconstriction, endothelial and platelet activation, and pro-inflammatory cytokine release. The KKS system typically causes vasodilation and regulates tissue repair, inflammation, cell proliferation, and platelet aggregation, but SARS-CoV-2 infection impairs such counterbalancing effects. This cascade results in cardiac arrhythmias, cardiac arrest, cardiomyopathy, cytokine storm, heart failure, ischemic myocardial injuries, microvascular disease, Kounis syndrome, prolonged COVID, myocardial fibrosis, myocarditis, new-onset hypertension, pericarditis, postural orthostatic tachycardia syndrome, pulmonary hypertension, stroke, Takotsubo syndrome, venous thromboembolism, and thrombocytopenia. In this narrative review, we describe and elucidate when, where, and how COVID-19 affects the human cardiovascular system in various parts of the human body that are vulnerable in every patient category, including children and athletes.

Published
2024
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21. Enhancing Parameters Tuning of Overlay Models with Ridge Regression: Addressing Multicollinearity in High-Dimensional Data

Author

Aris Magklaras, Christos Gogos, Panayiotis Alefragis, and Alexios Birbas

Subjects
overlay modeling, photolithography, parameters tuning, EUV lithography, semiconductor manufacturing, yield results, Mathematics, QA1-939
Abstract

The extreme ultraviolet (EUV) photolithography process is a cornerstone of semiconductor manufacturing and operates under demanding precision standards realized via nanometer-level overlay (OVL) error modeling. This procedure allows the machine to anticipate and correct OVL errors before impacting the wafer, thereby facilitating near-optimal image exposure while simultaneously minimizing the overall OVL error. Such models are usually high dimensional and exhibit rigorous statistical phenomena such as collinearities that play a crucial role in the process of tuning their parameters. Ordinary least squares (OLS) is the most widely used method for parameters tuning of overlay models, but in most cases it fails to compensate for such phenomena. In this paper, we propose the usage of ridge regression, a widely known machine learning (ML) algorithm especially suitable for datasets that exhibit high multicollinearity. The proposed method was applied in perturbed data from a 300 mm wafer fab, and the results show reduced residuals when ridge regression is applied instead of OLS.

Published
2024
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23. Access to and quality of elective care: a prospective cohort study using hernia surgery as a tracer condition in 83 countries

Author

Dönmez, A Eylül, Goswami, Aakansha Giri, Raheja, Aashna, Bhadani, Aayush, El Kady, Abd Elrahman Safwat, Alniemi, Abdalaziz, Awad, Abdalkarim, Aladl, Abdalla, Younis, Abdalla, Alwali, Abdallah, Khalil, Abdallah, Mansour, Abdallah, Elkhouly, Abdallah Mohamed, Rashad Temerik, Abdallah, Hasan, Abdallatef, Chied, Abdelhafid, Abdraba, Abdelhamid, Hrora, Abdelmalek, Abdelshafi, Abdelrahman, Alwali, Abdelrahman, Maraqa, Abdelrahman, Ghaffar, Abdul, Chekfa, Abdul Jabar, Al Balushi, Abdul Majeed, Quddus, Abdul, Hammadieh, Abdul Rahman, Muntaka, Abdul-Jalilu Mohammed, Asekun, Abdulazeez, Alshahrani, Abdulaziz, Jowharji, Abdulaziz, Alshukre, Abdulbaset, Khair Etareig, Abdulhafid, Abubakar Abdulkarim, Abdulhafiz, Ashiru, Abdulhafiz, Alailesh, Abdulhamid, Al-Mallah, Abdullah, Baydoun, Abdullah, Chaudhry, Abdullah, Askin, Abdullah Emre, Almutairi, Abdulmjeed, Belkhair, Abdulmunem, Abdllah, Abdulrahman, Alhammali, Abdulrahman, Basalim, Abdulrahman, Abouelnagah, Abdulrahman Galal Mohamed Mostafa, Ghazal, Abdulrahman, Mohammed, Abdulrahman, Qasem, Abdulrahman, Anadani, Abdulrazak, Jimoh, Abdulrazaq, Lawal, Abdulrazzaq Oluwagbemiga, Khaity, Abdulrhman, Lawal, Abdulwahab, Elzoubi, Abdurrahim Esseid, Sheshe, Abdurrahman Abba, Cetişli, Abdurrahman Furkan, Oyedele, Abeeb, Aljahdali, Abeer, Aboelnasr, Abeer Gamal Elsyed, Demessie, Abel, Bhargava, Abhilasha, Sonkar, Abhinav Arun, Bavaharan, Abhirame, Khan, Abid, Campbell, Abigail, Oyelekan, Abimbola Adeola Akintunde, Okunlola, Abiodun Idowu, Ojewuyi, Abiodun, Ekerin, Abiola, Saleh, Abobakr, Khairy, Abouelatta, Muthunayagam, Abraham Benjamin, Botha, Abraham, Teshome Sahilemariam, Abraham, Nawawi, Abrar, Muhammad, Abubakar Bala, Dahiru, Abubakar, Yahaya, Abubakar, Abdelmalik, Abubaker, Anuar, Abul Akmal Arif, Ousseini, Adakal, Leon -Del- Angel, Adalberto, Frankel, Adam, Gyedu, Adam, Lim, Adam, Lukáč, Adam, Peckham-Cooper, Adam, Sabbah, Adam, Varga, Adam, Sanou, Adama, Issaka, Adamu, Ningi, Adamu, Yeshitila, Addis, Yingess, Addisu, Olugbami, Adebayo, Moses, Damola-Okesiji, Adebola, Lawal, Adedayo, Ojo, Adedoyin, Hashmi, Adeel, Fakoya, Adegbolahan, Ishola, Adegoke, Abiodun, Adekunle, Ajayi, Adekunle, Mouffokes, Adel, Bonelli, Adele, Adekoya, Adeleke, Akeem Aderogba, Adeleke, Özcan, Adem, Ayoade, Ademidun, Adeyeye, Ademola, Agbaje, Ademola, Talabi, Ademola, Ademuyiwa, Adesoji, Adewumiya, Adesoji, Ademuyiwa, Adesoji O, Aderounmu, Adewale, Adisa, Adewale, Oke, Adewale, Ragab, Adham, Alzadjali, Adil, Baksi, Aditya, Jayapalan, Aditya, Md Yunos, Adnan, Pisanu, Adolfo, Salazar, Adolfo, Salinas Barragan, Adrian Alberto, Fox, Adrian, Stollberg, Adrian, Franco, Adriana, Neves, Adriana, Vricheva, Adriana, Hodonou, Adrien Montcho, Aghayeva, Afag, Liaquat, Affifa, Alsultan, Afnan, Morad, Afnan, Kalidis, Afroditi Angella, Gkouniaroudi, Agathi, Karakosta, Agathi, Lovi, Agbenya, Yevide, Agossou Barthélémy, Duro, Agustin, Rodriguez Gonzalez, Agustin, Tariq, Ahbala, Abaidalla, Ahmad, Abuhammad, Ahmad, Abuhantash, Ahmad, Mansour, Ahmad Adel, Ahmad Zaidi, Ahmad Al Hafeez, Alahmad Alismael, Ahmad, Alayed, Ahmad, Alfarwan, Ahmad, Alhaj, Ahmad, Ali, Ahmad, Alroobi, Ahmad, Alsheikh, Ahmad, Alusef, Ahmad, Alzu'Bi, Ahmad, Kayali, Ahmad Amir, Bouhuwaish, Ahmad, Doghaim, Ahmad, El-Sherbiney, Ahmad, Ghazal, Ahmad, Ramly, Ahmad Nasir, Raza, Ahmad, Qureshi, Ahmad Uzair, Arnaout, Ahmad Yamen, Abdelhamid, Ahmed, Abuthaher, Ahmed, Adel, Ahmed, Ahmayda, Ahmed, Al-Mouahhed, Ahmed, Alagha, Ahmed, Albalawi, Ahmed, Albhaisi, Ahmed, Alrifaee, Ahmed, Azam, Ahmed, Barakat, Ahmed, Al-Hajjaj, Ahmed Basim Abed, Dawoud, Ahmed, El Shamarka, Ahmed, El-Bastwesy, Ahmed, Elghrieb, Ahmed, Elkhalifa, Ahmed, Elmosalamy, Ahmed, Elshazli Mahmoud, Ahmed, Montaser, Ahmed G., Gbeadese, Ahmed, Haty, Ahmed, K. Ali, Ahmed, Awad, Ahmed K., Kedwany, Ahmed, Khalleefah, Ahmed, Abbas, Ahmed M., Allam, Ahmed M., Maher, Ahmed, Elsayed, Ahmed Mohamed, Mohamed Ibrahim Mohamed, Ahmed, Mostafa, Ahmed, Nabil, Ahmed, Nada, Ahmed, Ragheb, Ahmed, Abdelrahman, Ahmed Saber Mohamed, Sabry, Ahmed, Sakr, Ahmed, Elkhodary, Ahmed Salah, Shaheen, Ahmed, Ammar, Ahmed Siddique, Hameed, Ahmer, Akmercan, Ahmet, Aslan, Ahmet, Barcin, Ahmet, Ciftci, Ahmet Burak, Bozkurt, Ahmet Çağlar, Sarı, Ahmet Can, Yaşar, Ahmet Can, Develioğlu, Ahmet, Öztürk, Ahmet Mücteba, Sanli, Ahmet Necati, Rencuzogullari, Ahmet, Yildiz, Ahmet, Kaan, Ahmet Zahit, Toi, Ahouefa Chourika Sakinath, Aljamoudi, Aida, Cheung, Aiden Chak Kei, Gkoutoula, Aikaterini, Kalogeropoulou, Aikaterini, Sarafi, Aikaterini, Abo Al Shamat, Aiman, Sanon, Aimé Serge Titianma, Sanon, Aimée Florence, Hiller, Aimée, Costas-Chavarri, Ainhoa, Lombardero, Ainhoa, Fraile, Ainoa, Bojazyah, Aisha, Kamal, Aisha, Gill, Aisling, Hada, Aïssatou, Gulla, Aiste, Mačiulaitytė, Aistė, Sukumar, Aiswarya, Landaluce-Olavarria, Aitor, Sainz Lete, Aitor, Pal, Ajay Kumar, Malik, Ajaz Ahmad, Horiguchi, Akihiko, Kocaay, Akin Firat, Akinkuolie, Akinbolaji, Olabode, Akingunloye, Fadipe, Akinniyi, Akinmade, Akinola, Darkwa Boateng, Akosua, Appiah-Kubi, Akosua Yeboaa, Alkaseek, Akram, Kadamani Abiyomaa, Akram, Anand, Akshay, Oppong, Akua, Opoku-Agyapong, Akwasi, Asharaf, Al Ameen, Ahmed, Al Samoul, Andani, Al-Hassan Dasana, Alkharusi, Al-Salt, Abd Elsattar, Alaa, Alragheai, Alaa, Alsalahat, Alaa Atta, Hawarah, Alaa, Aldirani, Alaa Nasib, Shabkah, Alaa, Nixon Fulli, Alafi Francis, Nguyen, Alain, Mustafa, Alamin, Joseph, Alan, Huws, Alaw, Aregawi, Alazar Berhe, Sanchez Gallego, Alba, Torroella, Alba, Vazquez Melero, Alba, Dauksa, Albertas, Abreu Da Silva, Alberto, Brun-Peressut, Alberto, Barranquero, Alberto G, Gegúndez Simón, Alberto, Gerundo, Alberto, Navarrete-Peón, Alberto, Viacava, Alberto, Vilar, Alberto, Adam, Albushra Altayeb, Jarimba, Aldo, Johnson, Aleena, Nuñez Venzor, Alejandra, Gonzalez Ojeda, Alejandro, Romero De Diego, Alejandro, Karamarkovic, Aleksandar, Butyrskii, Aleksandr, Edmundson, Aleksandra, Sidorova, Aleksandra, Thomas, Alen, Tomazic, Ales, Giuliani, Alessandra, Iodice, Alessandra, Marano, Alessandra, Marello, Alessandra, Ongaro, Alessandra, Saba, Alessandra, Anastasi, Alessandro, Borello, Alessandro, Broglia, Alessandro, Carta, Alessandro, Finocchio, Alessandro, Francia, Alessandro, Iacomino, Alessandro, Izzo, Alessandro, Ottaiano, Alessandro, Spaziani, Alessandro, Strumia, Alessandro, Biancafarina, Alessia, D'Ignazio, Alessia, Davolio, Alessia, Morello, Alessia, Licciardello, Alessio, Mazzoni, Alessio, Wilkins, Alex, Arekhandia, Alexander, Barlas, Alexandros, Chamzin, Alexandros, Demetriou, Alexandros, Giakoustidis, Alexandros, Kozadinos, Alexandros, Kyriakidis, Alexandros, Sarakatsanos, Alexandros, Rojas, Alexei, Saridaki, Alexia, Litchinko, Alexis, Arnaud, Alexis P, Binder, Alf-Dorian, Yakubu, Alfa, Kavalakat, Alfie, Shamsutdinova, 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N, Felix, Alahmad, Feras, Alnimri, Feras, Haddad, Feras, Gool, Ferhana, Castro, Fernanda, Diaz, Fernanda, Lucero, Fernanda, Vovola, Fernanda, Mahnic, Fernando, Mercado Sanchez, Fernando, Prieto La Noire, Fernando, Soggiu, Fiammetta, Tsige, Fikreab, Brzeszczyński, Filip, Rudisch, Filip, Valente Costa Pinto, Filipa, Ramalho De Almeida, Filipe, Banchini, Filippo, Palomino Escalante, Fiorella, Fadzlullah, Fitri, Terefe, Fitsum, Sulo, Fjorenta, Ciccarone, Flavia, Tirelli, Flavio, Krämer, Florian, Grama, Florin, Spanos, Foivos, Solimene, Folco, Akinwande, Foluso, Osman, Forzia, Stefou, Foteini, Kyramargios, Fotios, Stavratis, Fotios, Alassani, Fousseni, Ascari, Francesca, Cammelli, Francesca, D'Agostino, Francesca, Tropeano, Francesca Paola, Peters, Francesca, Ré, Francesca, Brucchi, Francesco, Casti, Francesco, Coratti, Francesco, Ferrara, Francesco, Floris, Francesco, Izzo, Francesco, Maffei, Francesco, Palmieri, Francesco, Pata, Francesco, Porcelli, Francesco, Selvaggi, Francesco, 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Judy, Mühlhäusser, Julia, Sidorovskaia, Julia, Carrizo, Julian, Napoli, Juliana, Pereira-Macedo, Juliana, Ribeiro, Juliana, De Deken, Julie, Nnoli, Juliet, Paredes, Julieta, Zevallos-Quiroz, Julio Cesar, Gonzalez Garcia, Julio, Adjei, Julius, Olaogun, Julius, Kutkevičius, Juozas, Metzger, Jürg, Košir, Jurij Aleš, Kosir, Jurij, Seyi-Olajide, Justina, Zajac, Justyna Karolina, Dhima, Jyoti, Dhiman, Jyoti, Shreyas, K, Türker, Kadir Yağız, Lee, Kai, Khutsishvili, Kakhi, Yu, Kam Keung Auston, Das, Kamala, Özdoğan, Kamil, Reddy, Kamireddy Madana Raghava, Kabulov, Kamran, Nahar, Kamrun, Rajaratnam, Kanapathippillai, Wijesinghe, Kanchana, Sevnaran, Kapil, Khalil, Karam, Singh, Karanbir, Fayed, Kareem, Booyse, Karien, Geiger-Timm, Karin, Maharaj, Karl, Bhutia, Karma, Richter, Karolina, Komorowska, Katarzyna, Urbańska, Katarzyna, Waddell, Kate, Kambouri, Katerina, Tata, Katerina, Richetti, Katharina, Griffin, Katherine, McKenzie, Katherine, Tambudze, Katherine, Hall, Katheryn, Chu, Kathryn, Theodoropoulou, Katina, Kröning, Katrin, Bozada-Gutiérrez, Katya, Raghuwanshi, Kaustubh, J B, Kavitha, Ahmed Ibrahim, Kefah, Bwala, Kefas John, Iles, Kelly, Jasso García, Kelvin, Oğur, Kemal, Fretwell, Kenneth, Oluchukwu, Kenneth, Onyekachi, Kenneth, Voon, Kenneth, Oderoha, Kevin Ewomazino, Nieto Yrigoin, Kevin, Quispe De La Roca, Kewin, Anaam, Khadega, Bensmain, Khadija, Shwail, Khadija, Akter, Khadiza, Sawaftah, Khaled Ahmad, Shamiyah, Khalid Adnan, Bhatti, Khalid, Mohammed, Khalid Miftah Ghuraybeel, Ayyoub, Khalil, Cholah, Khalil, Rahman, Khandakar Rezwanur, Abdulrahman, Khawla, Al-Shami, Khayry, Hayat, Khizar, Al Hinai, Khulood, Taghavi, Kiarash, Shodunke, Kikelomo, Abo Zaal, Kinaz, Ewool, Kingsley, Gaikwad, Kiran, Shemyatovsky, Kirill, Dey, Kirsty Elaine, Mishra, Kirti Kumar, Rathod, Kirtikumar J, Senanayake, Kithsiri Janakantha, Noguchi, Kiyonari, Kordeni, Kleoniki C., Dembele, Klétigui Samuel, Spassov, Kolyo, Khalid, Komal, Petrenko, Konstantin, Bekiaridou, Konstantina, Rekouna, Konstantina, Athanassiou, Konstantinos, Avgerinos, Konstantinos, Bouchagier, Konstantinos, Bouliaris, Konstantinos, Bramis, Konstantinos, Iliakopoulos, Konstantinos, Kontzoglou, Konstantinos, Ntatsis, Konstantinos, Pavlopoulos, Konstantinos, Perivoliotis, Konstantinos, Polychronopoulos, Konstantinos, Giannakopoulos, Konstantinos S., Zakkas, Konstantinos, Zapsalis, Konstantinos, Koumarelas, Konstantinos-Eleftherios, Mori, Krinal, Ooi, Krisada, Ascencio Diaz, Kriscia Vanessa, Jasaitis, Kristijonas, Nieuwenhuys, Kristin, Atherton, Kristy, Smith, Kristy, Sharma, Kruti, Jaffry, Kumail, Lehmann, Kuno, Ayad, Kusay, Luthra, Kush Kumar, Nanayakkara, Kushan, Agbedinu, Kwabena, Oduro-Boateng, Kwaku Boakye, Boakye-Acheampong, Kwame, Sim, Kwang Kiat, Yalley, Kwekuma, Collins, Kyeremeh, Muscat, Kyle, Hofmann, Kyra, Lambri, Kyriaki, Bananis, Kyriakos, Nassim, Kyrillos, Allan, Lachlan, Codina Corrons, Laia, Hijazein, Laith, Moolla, Laith, Sweidan, Laith, Rai, Lajpat, Devi, Lakshmi, Fountoulis, Lampros, Andreski, Lara, Bonello, Lara, Rodrigues Madeira, Lara, Tafesh, Lara, Yasin, Lara, Martinez, Laura, Fortuna, Laura, Peña Balboa, Laura Gabriela, García-Zambrano, Laura, Bolaños, Laura Isabela, Jiménez, Laura, Lely, Laura, Ortega Lechuga, Laura, Rossi, Laura, Rubin, Laura, Ruiz-Villa, Laura, Sequi, Laura, Sahan, Laura-Ann, Johnstone, Lauren, Monteiro, Lauren, Abdullahi, Lawal Barau, Jovcheski, Lazo, Siragusa, Leandro, Kang, Leannedra, Elgebaly, Leenah, Mansour, Lefteris, Robine-Durnell, Lélia, Bray, Lemuel Davies, Mohammed, Lena, Licari, Leo, Onyebulu, Leonard, Chieng, Leonard Ron, Solaini, Leonardo, Chardalias, Leonidas, Fountarlis, Leonidas Ilias, Van Den Hil, Leontine, Tapia Moral, Leopoldo, Petashvili, Leri, Heeren, Letícia, Laface, Letizia, Niyidukunda, Lewis, Barnard, Liam, Torres Bavestrello, Lidice Veronica, Hasan, Lilav, Dyab, Lima, Venclauskas, Linas, Beukes, Linda, Gabellini, Linda, Liepa, Linda, Zeng, Lingjuan, Dubs, Linus, Rampersad, Lisa, Catozzi, Livio, Castro, Lizeth, Milic, Ljiljana, Shawesh, Lobna, Anyanwu, Lofty-John, Khalifa, Lojina, Cheng, Lok Pong, Manoj Joshua, Lokavarapu, Shammas, Lora, Fuentes Rivera Lau, Lorena, Rodríguez Gómez, Lorena, Capello, Lorenzo, Epis, Lorenzo, Fatucchi, Lorenzo Maria, Rende, Lorenzo, Ripamonti, Lorenzo, Ackam, Louis, Moniz, Lourenço, Bains, Lovenish, Alriyami, Lubna, Alokshi, Lubnah, Martinek, Lubomir, Tulinsky, Lubomir, Samison, Luc, Lo Piccolo, Luca Benedetto, Cardinali, Luca, Nespoli, Luca Carlo, Casingena, Luca, Degrate, Luca, Bonomo, Luca Domenico, Morelli, Luca, Ottaviani, Luca, Resca, Luca, Scaravilli, Luca, Schiavone, Luca, Theuil, Luca, Casalduero, Lucas, Lee, Lucas D., Granero, Lucas, Caram, Lucas Jose, Barni, Lucia, Cidade Costa, Luciana, Paredes, Luciana, Poggi, Luciano, Marquez, Lucila, Garciandia, Lucio, Taglietti, Lucio, Pramod, Ludiya, Stella, Ludovica, Carbone, Ludovico, Bracciano, Luigi, Cobellis, Luigi, Conti, Luigi, Fedele, Luigi, Ragazzini, Luigi, Simonelli, Luigi, Verre, Luigi, Flores Chávez, Luis Adrián, Rea Bocanegra, Luis Alberto, Pelayo Orozco, Luis Ángel, Asensio Gomez, Luis, Bravo, Luis, Flores Chávez, Luis Manuel, Poggi, Luis, Cabezudo, Luis Ramón, Sante Serna, Luis, Tallon-Aguilar, Luis, Talé-Rosales, Luis-Fernando, Chantada, Luisa, Moreira, Luísa, Hasan, Lujain, M Mheidat, Lujain, Eisner, Lukas, Gantner, Lukas, Havranek, Lukas, Majerčák, Lukáš, Pánči, Lukáš, Nawacki, Łukasz, Adagrah Aniakwo, Luke, Bromley, Luke, Green, Luke, Paterson, Luke, Peters, Luke, Abdur-Rahman, Lukman, Omomeji, Lukman, Amosu, Lukmon, Kolongi, Lungushinga Christopher, Bin Aizan, Luqman Naim, Imchen, Lurong, Chang, Lydia, Mukamazera, Lydie, Katsiaras, Lykoyrgos, Al-Boukhari, Lynn, Chong, Lynn, Karydakis, Lysandros, Peris, M. Roosindu, Cancelas, Mª Dolores, Kariem, Maahir, Amoako-Boateng, Mabel, Alshamikh, Mabroukah, Ishak, Mabruok, Narayanan, Machingal, Matyja, Maciej, Walędziak, Maciej, Zounon, Mack-Arthur, Trindade, Madalena, Shahid, Madeeha, Kelly, Madeleine, Bajwa, Madiha, Bowles, Madison, Roussos, Madison, Sampaio-Alves, Mafalda, Manfredini, Magda, Kołomańska, Magdalena, Redynk, Magdalena, Farooq, Maham, Ali, Mahamudu Ayamba, Rodha, Mahaveer Singh, Alsalawi, Mahdi, Lodha, Mahendra, Sethi, Mahesh Kumar, Khalil, Mahfoud, Singh, Mahima, Abdualqader, Mahmmoud yehia, Abdelhafez, Mahmood, Sersarah, Mahmood, Abdelreheem, Mahmoud, Abu Al Amrain, Mahmoud, Barbarawi, Mahmoud, Diab, Mahmoud, Eissa, Mahmoud, ElFiky, Mahmoud, Elmesalmi, Mahmoud, Elmousili, Mahmoud, Fahmy, Mahmoud, Faisal, Mahmoud, Jabal, Mahmoud, Saad, Mahmoud M., Mahafdah, Mahmoud, Marei, Mahmoud Marei Abdelaziz, Mostafa, Mahmoud, Reda, Mahmoud, Zahran, Mahmoud, Suleman, Mahmowd, Genç, Mahmut Salih, Haghighat Ghahfarokhi, Mahta, Abubakar, Maimuna, Haimona, Mairarangi, Camuera, Maite, H. Oweidat, Majd, Mansour, Majd, Kalabić, Majda, MohammedAli, Majdeddin, Abu Daoud, Majdi, Almahjoub, Majdolin, Bilfaqirah, Majed, Yigah, Makafui, Akkawe, Malak, Dery, Malcolm, West, Malcolm, Rius, Malena, Nandasena, Malith, Aljarawn, Mallak, Masaaod, Mallak, Manangi, Mallikarjuna, Windsouri, Mamadou, Battili, Mamata, Rakotonaivo, Mamisoa Judicaël, Benghazi, Manaji, Al-Dhaheri, Manal, Almaqrahi, Manal, Katif, Manal, Alshami, Manar, Ibrahim, Manar, Ramazanov, Manas, Kaur, Mandeep, Agrawal, Manish Kumar, Pathak, Manish, Aggarwal, Manisha, Chandrasegaram, Manju, Anandan, Manoj, K S D, Manoj Kishan Lal, Kumar, Manoj, Sarda, Manoj, K B, Manojkumar, Jokubauskas, Mantas, Moreno Gonzales, Manuel Arturo, Cruz, Manuel, Diez Alonso, Manuel, Garcia, Manuel, Perez, Manuel, Mosquera Paz, Manuel Santiago, Cammelli, Manuela, Mercurio, Manuela, Singh, Manvinder, Taamreh, Manwa, Canals Sin, Mªpilar, Carbonell Pradas, Mar, Nunes, Mara, Sawaftah, Marah Ahmad, Khalil, Maram, Schneider, Marcel André, Steffani, Marcella, Pisano, Marcello, Doniquian, Marcelo Alejandro, Martínez Bareiro, Marcelo Nicolás, Pagani, Marcelo, Scortechini, Marcelo, Carvalho, Márcia, Sánchez Audelo, Marco Antonio, Brizzolari, Marco, Ceresoli, Marco, De Prizio, Marco, Amisano, Marco Francesco, Gramellini, Marco, Marcianò, Marco, Mariani, Marco, Milone, Marco, Montagna, Marco, Piccino, Marco, Santos, Marco, Dyer, Marcus, Kang, Marcus, Mahadi, Mardhiana, Zawadzki, Marek, Yinusa, Margaret, Bernardo, Margarida, Nunes Luís, Margarida, Gambelli, Margherita, Flint, Margot, Aggelidou, Maria, Bequis, Maria Agustina, Sotiriou, Maria Aikaterini, Ñañez, Maria Alejandra, Tahir, Maria Ambreen, Gascón Domínguez, María Ángeles, Asimakidou, Maria, Mourato, Maria Beatriz, Blanco, Maria, Christou, Maria, Coronas Soucheiron, Maria, Pignanelli, Maria Costanza, Kalaydjian, María Cristina, Martí-Ejarque, Maria del Mar, Olmedo Reinoso, María Del Mar, Cebollero, María Del Pilar, Derattani, Maria, Gama Caldeira, Maria Do Carmo, Drogouti, Maria, Gonzalez-Gonzalez, Maria Elena, Muñoz Fernández, María Elena, Muriel, María Emilia, Duran, María Eugenia, Zarate Casas, María Fernanda, Florou, Maria, Piacentini, Maria Gaia, Seixo, Maria Inês, Bellini, Maria Irene, Peña Soria, Maria Jesús, Martínez, María José, Medina, Maria José, Rueda Medécigo, María José, Karakeke, Maria, Kausar, Maria, Kyriazi, Maria, Marqueta De Salas, Maria, Modolo, Maria Marta, Mateu, Maria, Mavri, Maria, El Ghoul Miliotou, Maria Melina, Moreno Gijon, Maria, Papadoliopoulou, Maria, Proclamà, Maria Pia, Picciochi, Maria, Reis, Maria, Rennis, Maria, D'Anna, Maria Rosa, Ruffoli, Maria, Ruiz Soriano, María, Sánchez Ramirez, Maria, Sánchez-Rubio, María, Schüler, Maria, Sotiropoulou, Maria, Barrio Renteria, Maria Teresa, Tsopozidi, Maria, Vasconcelos, Maria, Facchino, Maria Vittoria, Wikar, Maria, Aguilera-Arevalo, Maria-Lorena, Abdu, Mariam, Asarbakhsh, Mariam, Elmiesiry, Mariam, Ashong, Marian Esi, Gomes, Mariana, Capuano, Marianna, Lill, Marianne, Nieto Galvan, Mariano, Osso, Mariasara, Olivos, Maricarmen, Sacdalan, Marie Dione, Weber, Marie-Christin, Gonzalez, Marijose De Cristo, Ferreira, Marília, Infantes Ormad, Marina, Kouliou, Marina Nektaria, Ransome, Marina, Vicario Bravo, Marina, Cuesta Argos, Mario, Faletar, Mario, Giuffrida, Mario, Lainez Escribano, Mario, Pacilli, Mario, Pannullo, Mario, Rodriguez-Lopez, Mario, Trejo-Avila, Mario, Merrakos, Marios, Tello Jimenez, Marisol, Kalisvaart, Marit, Quaunine, Marium, Perera, Mariyan, Harris, Mark, Youssef, Mark Melad Thabet, Peter, Mark, Philipp, Mark, Portelli, Mark, Jesudason, Mark Ranjan, Sammut, Mark, Tomlinson, Mark, Zammit Vincenti, Mark, Despotidis, Markos, Albertsmeier, Markus, Quante, Markus, Löffler, Markus W., Gurung, Markush, Gumsheimer, Marlena, Benamrouche, Maroua, Chaccour, Maroun, Ahmed, Marriam, Farooqui, Marryam Riaz, Angelini, Marta, Ortega Escudero, Marta, Martin Gimenez, Marta Pilar, Reia, Marta, Scricciolo, Marta, Caramantin Obando, Martha Maria, Gosselink, Martijn, Bertrand, Martin, Dum, Martin, Kajic, Martin, Karamanliev, Martin, Kyereh, Martin, Lucchini, Martin, Schön, Martin, Morna, Martin Tangnaa, Binda, Martina, Ceolin, Martina, Martorana, Martina, Zambon, Martina, Shams, Marvi, Alansary, Marwa, Alnuwayli, Marwa, Khalifa, Marwa, Bahnacy, Marwan, Iqreewi, Marway, Nnabagulanyi, Mary, Saleem, Marya, Alhimyar, Maryam, Kamal, Maryam, Masood, Maryam, Razaq, Maryam, Siddique, Maryam, Lazo Ramírez, Maryzela, Edeeb, Masaoud, Solkar, Maseera, Adetoyi, Mashood, Adeniyi, Caccetta, Massimiliano, Casati, Massimiliano, Veroux, Massimiliano, Dugo, Massimo, Bevanda, Mateo, Santillan, Mateo, Mietła, Mateusz, Pryt, Mateusz, Muir, Mathew, Bei, Matilda, McGuinness, Matt, Aulicino, Matteo, Castrovillari, Matteo, Filardo, Matteo, Palmeri, Matteo, Pisano, Matteo, Rottoli, Matteo, Gjoka, Mattheus, Binks, Matthew, Corcos, Matthew, Kwon, Matthew, Maybury, Matthew, Sammut, Matthew, Tutton, Matthew, Watson, Matthew, Biebl, Matthias, Janda, Matthias, Maak, Matthias, Wichmann, Matthias, Berselli, Mattia, Gritti, Mattia, Molteni, Mattia, Pacilli, Maurizio, Favoriti, Mauro, Garino, Mauro, Podda, Mauro, Santarelli, Mauro, Alfaid, Mawada, Albert, Mawadri Jimmy Isaac, Oyortey, Mawuenyo Attawa, Enßlin, Max, Berlet, Maximilian, Brunner, Maximilian, Kießler, Maximilian, Scheiterle, Maximilian, Sohn, Maximilian, Busch, Maximiliane, Perkins, Maya, Sabboh, Maya, Badkur, Mayank, Okudero, Mayowa, Mohamedshafee, Maysoon, Al-Juaifari, Maytham Aqeel, Elesseily, Mazen, Mohammad, Mazen, Nikberg, Maziar, Jean Claude, Mbonicura, Şermet, Medeni, Chisthi, Meer, Luthra, Meera, Sulciner, Megan, Kaple, Meghali, Bhat, Meghana, Koç, Mehmet Ali, Avci, Mehmet Alperen, Kizilkaya, Mehmet Celal, Kara, Mehmet Emin, Ozcelik, Mehmet Faik, Ozsoy, Mehmet Sait, Zaigham, Mehreen, Mesfin, Mekdelawit, Kalender, Mekselina, Mellado Tellez, Mel Paul, González De Miguel, Melania, Farrugia, Melanie, Theodoridou, Melanie, Barcelona, Melden Darrell, Aktas, Melik Kagan, Fernández Zurita, Melissa Andrea, Bautista, Melissa, Park, Melissa, Rodríguez-Ordoñez, Melissa-Zohemia, Yashar, Meltem, Worku, Mengistu, Al-Fraijat, Meran, Estaire Gómez, Mercedes, Shoshkova, Meri Danailova, Kruščica, Merima, Tanal, Mert, Çuhadar, Merve, Tokocin, Merve, Agyapong, Meshach Manu, Erkaya, Metincan, Okechukwu, Mgbako, Adinku, Michael, Bickford, Michael, Ediale, Michael, Issa, Michael, Konstantinidis, Michael K., Lie, Michael, M. Nathan, Michael, Maclean, Michael, Nortey, Michael, Pellen, Michael, Pham, Michael, Pitiakoudis, Michael, Singh, Michael Prodip, Spartalis, Michael, Van Der Colf, Michael, Wilson, Michael, Billis, Michail, Karanikas, Michail, Papamichail, Michail, Vailas, Michail, Kisielewski, Michał, Kusiński, Michał, Nycz, Michał, Święch, Michał, Fagbayimu, Micheal, Adamina, Michel, Fiogbe, Michel, Prudhomme, Michel, Angelucci, Michela, Campanelli, Michela, Cricrì, Michele, Grande, Michele, Manigrasso, Michele, Scopelliti, Michele, George, Michelle, Mozel, Michelle, Galasyuk, Mick, Chevallay, Mickael, Giuliano, Micol, Dobón Rascón, Miguel Ángel, Fernandez Romero, Miguel Angel, García Ureña, Miguel Ángel, Zaragoza Mendieta, Miguel Ángel, Bejarano Serrano, Miguel, Brito, Miguel, Calderon, Miguel, Jurado Román, Miguel, Palas, Miguel, Li Valencia, Miguel Roberto, Sebastián-Mendoza, Miguel-Julián, Muresan, Mihai-Stefan, Slavchev, Mihail, Agapov, Mikhail, Milentijević, Milica, Catterall, Millie, Stjepanovic, Milos, Doss, Mina, Natey, Mina, Aikins, Minas, Mattis, Minca, Ekanayake, Minoli Tharushika, Tora, Mir Mehrab Sharmin, Alsharayri, Mira, Shalaby, Mira, Boras, Miran, Riba Martínez, Mireia, Mogiatti, Mirella, Salibašić, Mirhan, Biancu, Miriam, Cappiello, Miriam, Koschke, Miriam Luise, Sadek, Mirna, Szura, Miroslaw, Horga, Miruna, Dason, Mishael, Tayyab, Mishal, Imirski, Mitko, Pejović, Mladen, Tabaza, Mo'Ath, Alneasan, Moaaz, Shalkamy, Moamen, Issa, Moammad Issa, Erfan, Moatasem, Ewedah, Moataz, Srour, Moayad, Beletachew, Moges, Abbas, Mohamad, Farho, Mohamad Ali, Marawy, Mohamad Kher, Klib, Mohamad, Morjan, Mohamad, Sawas, Mohamad Nabhan, Elghriani, Mohamed Abdelbaset Masoud, Abdelmaboud, Mohamed, Abdelmaksoud, Mohamed, Abdullahi, Mohamed, Abo Abdo, Mohamed, Ahmed, Mohamed, Ahmoud, Mohamed, Al Sayed, Mohamed, Suliman, Mohamed Almouafaq, Alsori, Mohamed, Altajouri, Mohamed, Assalhi, Mohamed, Berrakkouch, Mohamed, Elnour, Mohamed, Abdelsalam, Mohamed Elsayed Elaraby Abdelrahim, Elsayed Metwally, Mohamed, Hajalamin, Mohamed, Kamal Matter, Mohamed, Khaled, Mohamed, Kouta, Mohamed, Masoud, Mohamed, Almihashhish, Mohamed Miftah, Mokhtar, Mohamed, Mostafa, Mohamed, Yassin, Mohamed Musa, Bouhafs, Mohamed Nedjmeddine, Herdan, Mohamed Omar, Omer, Mohamed, Osman, Mohamed, Zaazou, Mohamed, Zahed Abdalla, Mohamed, Melouane, Mohamed-Sami, Abed, Mohammad, Sawaftah, Mohammad Ahmad Mohammad, Al-Masri, Mohammad, Al-Qannas, Mohammad, Ali-Hassanzadeh, Mohammad, Yunus, Mohammad Alif, Aloulou, Mohammad, Alrantisi, Mohammad, Araydah, Mohammad, Bani Hani, Mohammad, Barakat, Mohammad, Durrani, Mohammad, Khan, Mohammad Faisal, Dwikat, Mohammad Fuad, Hasan, Mohammad, Nabhan, Mohammad Hassan, Hijazi, Mohammad, Abu Albahrain, Mohammad Karam, Barakat, Mohammad Mounzer, Mubarak, Mohammad, Omar, Mohammad, Pourfridoni, Mohammad, Mslmani, Mohammad Rabee, Salah, Mohammad, Tanashat, Mohammad, Yahmad, Mohammad, Elmujtaba, Mohammed, Abd Al-Fattah, Mohammed, Abdelkabir, Mohammed, Abosedra, Mohammed, Sarker, Mohammed Abu Kawsar, Abudabbous, Mohammed, Abuwarda, Mohammed, Elgak, Mohammed Ahmed, Al Hinai, Mohammed, Al Zebda, Mohammed, Al-Shehari, Mohammed, Alharthi, Mohammed, Ali, Mohammed, Ismael Alamin, Mohammed Ali, Alqadasi, Mohammed, Alshanwani, Mohammed, Alshehri, Mohammed, Asaad, Mohammed, Bashir, Mohammed, Bohlala, Mohammed, Meghaizerou, Mohammed El Amine, Albanna, Mohammed Emad Hashem, Ghunaim, Mohammed, Goga, Mohammed, Hajhamad, Mohammed, Hamada Takrouney, Mohammed, Hammoda, Mohammed, Hamoud Almahly, Mohammed, Muragi, Mohammed, Mohammed, Mohammed Mustafa Hassan, Obaid, Mohammed, Omar, Mohammed, Said, Mohammed, Salah, Mohammed, Saleh Khatab, Mohammed, Aliyu, Mohammed Salele, Shakhshir, Mohammed, Sheriff, Mohammed, Tageldin, Mohammed, Abdelfattah, Mohanad, Daher, Mohanad, Lotfy, Mohanad, Alqedrh, Mohannad, Nasani, Mohannad, Mohd Shah, Mohd Shahrulsalam, Madany, Mohie El-Din Mostafa, Mobolaji-Ojibara, Mojisola, Nkogatse, Moleseng, Alazabi, Mona, Gupta, Money, Bogdan, Monica, Guerrero, Monica, Noguez Castillo, Monica, Gureh, Monika, Kacem, Montasser Jamaleddine, Tarar, Moosa Feroze, Seto, Morel, Steinruecke, Moritz, Edena, Morrison, Abdulsalam, Moruf, Abdelhadi Suliman Adam, Mosab, Saleh, Mosab, Anati, Mosaikah, Dokurugu, Moses Abdulai, Agunloye, Moses, Ibadin, Moses, Momoh, Moses, Abdelkarim, Mostafa, Kamar, Mostafa, Kotb, Mostafa, Mahran, Mostafa, Mohamad Amin, Mostafa, Shalaby, Mostafa, Waseem, Mostafa, Almaletti, Motasem, Saifi, Motaz, Tsuruta, Motohisa, Agbadebo, Mouhamed, Arnaout, Moumen, Ojo, Moyosoluwa, Sharma, Mrthyunjayani, Azzuz, Muad Mohamed Ramadan, Haj Hussein, Mudar, Ameen, Muftiat Omolola, Nkoronko, Mugisha, Fitri, Muhamad, Abdullah, Muhammad, Bashir, Muhammad Ahmad, Sadiq, Muhammad Ahmad, Ahmed, Muhammad, Ali, Muhammad, Al-Yusuf, Muhammad Ali, Haider, Muhammad Aliyan, Alshaar, Muhammad, Mirza, Muhammad Bilal, Che Yaacob, Muhammad, Daniyan, Muhammad, Elzayat, Muhammad, Butt, Muhammad Faizan, Sadiq, Muhammad Hamza, Chishti, Muhammad Haris, Ismail, Muhammad Izzat Shufphi, Kashif, Muhammad, Khalid, Muhammad, Mansoor Iqbal, Muhammad, Bin Khalid, Muhammad Moaz, Rafique, Muhammad Nouman, Raheem, Muhammad, Khalid, Muhammad Saud, Usama, Muhammad, Usman Malik, Muhammad, Saqib, Muhammad Waleed, Elhadi, Muhammed, Ateş, Muhammed Ikbal, Demirpolat, Muhammed Taha, Ergenç, Muhammer, Bello, Muideen, Kulimbet, Mukhtar, Nyirenda, Mulinda, Taeme, Mulugeta, Denini, Muna, Aziz, Munazzah, Yahaya, Mundashiru, Eugene, Muneza, Amadu, Munira, Chauhan, Munish, Acar, Murat, Teressa, Murti, Dauphin, Muryango, Arafat, Musa, Althomali, Musab, Rayzah, Musaed, Husain, Musharraf, Tolani, Musliu Adetola, Abu Jayyab, Mustafa, Al-Attraqchi, Mustafa, Kara, Mustafa Alper, Seker, Mustafa Ege, Gün, Mustafa, Hamed, Mustafa, Mehanny, Mustafa, Oncel, Mustafa, Sabri Massadi, Mustafa, Uyanik, Mustafa Safa, Uzunoglu, Mustafa Yener, Abdullahi, Mustapha, Saidani, Mustapha, Nofal, Mutaz, San, Myat, Ishak, Myrna, Keramida, Myrto D., Nik Burhanuddin, N.M. Syahrin, Talat, Nabila, Shehata, Nada, Alasbahi, Nadeen, Marcos, Nádia, Al Amri, Nadiah, Absy, Nadine, Parker, Naeelah, Lindi, Naeimah, Omer, Nafisa, Papadogianni, Nafsika, Rawal, Nagendra, Ismaiel, Nahar, Ben Hasan, Najat, Albahloul, Najla, Gokhare Viswanath, Nakul, Srinivas, Namitha, Christian, Nana Ama, Obuobi, Nana Kwame Asare, Beharry, Naomi, Yousefzadeh Kandevani, Naser, Alnamari, Nashwan, Oyelowo, Nasir, Oloko, Nasirudeen, Alzerwi, Nasser, Mosbah, Nasser, Shulman, Nastassia, Andrade, Natacha, Boumas, Natacha, Cobeño Tamayo, Natalia, Barrera Lopez, Natalia Guadalupe, Palamara, Natalia, Blencowe, Natalie, Marzouqa, Natalie, Blencowe, Natalie S, Salgadoe, Natalie, Techapongsatorn, Nathakorn, Paez, Nathaly, Ekwo, Nathan, Saini, Navdeep, Malik, Naveed Akhtar, Sharma, Naveen, Kumar, Navin, Chaudhry, Navneet Kumar, Karimbocus, Nawaaz, Rasool, Nazeerah, Lodhi, Nazia, Kavak, Nazli, Ildephonse, Ndayiragije, Diomede, Nduwimana, Bayleyegn, Nebiyou S., S.Bayleyegn, Nebiyou, Jović, Nediljko, Mosleh, Neebal, Aruldas, Neerav, Kapur, Neeti, Paul Sigamony, Negine Paul, Karthikeyan, Neha, Tabatabaian, Nelia, Affram, Nelson, Agboadoh, Nelson, Tran, Nelson, Lalovic, Nenad, Agugua-Obianyo, Nene, Kullab, Nermen, Lahmer, Nesrin, Raiq, Neven, Soldo, Neven, Spiteri, Neville, Chen, Nevin, Al Rabadi, Nezar, Christian, Ngarambe, Cabrel, Ngongang Ngansop, Leonelle Lore, Nguefack Noudem, Furbetta, Niccolò, Ensor, Nicholas, Tsantikos, Nick, Seeger, Nico, Cillara, Nicola, Eardley, Nicola, Petrarota, Nicola, Tartaglia, Nicola, Feijoo, Nicolas, Finocchiaro, Nicole, Koter, Nicole, De Santis, Nicolò, Fabbri, Nicolò, Schiavon, Nicolò, Tamini, Nicolò, Sharma, Nidhi, Sánchez Fuentes, Nieves, Solomon, Nigus, Bugdayci, Nihat, Lekiashvili, Nika, Gupta, Nikhil, Narain, Nikhil, Uttam, Nikita, Kłos, Nikola, Ververidis, Nikolaos Adrianos, Arkadopoulos, Nikolaos, Dimitrokallis, Nikolaos, Garmpis, Nikolaos, Gouvas, Nikolaos, Kalampokis, Nikolaos, Kopanakis, Nikolaos, Kydonakis, Nikolaos, Machairas, Nikolaos, Memos, Nikolaos, Michalopoulos, Nikolaos, Mathioudakis, Nikolaos Nestor, Roukounakis, Nikolaos, Stamos, Nikolaos, Tasis, Nikolaos, Tsakiridis, Nikolaos, Vlachakos, Nikolaos, Zampitis, Nikolaos, Kouzakos, Nikolas, Börner, Nikolaus, Dimitriou, Nikoletta, Dafnios, Nikos, Banerjee, Niladri, Klammer, Nils, Maharjan, Nima, Rabai, Nimah, Oscar, Nimpaye, Harrison, Nina, Kheyrbek, Nina, Kansakar, Nirajan, Bhat, Nisar, Krishnappa, Nischal, Pahuja, Nisha, Paul Ambrose, Nitin, Renovat, Niyongabo, Musawa, Nizar, Nwanne, Njideka, Steve, Nkurunziza, Chidumije, Nnaemeka, Nwafulume, Nnaemeka, Celestine, Nnamani, Duru, Nnamdi, López Bernal, Noelia Esthela, Laquatra, Noemi, Pasqua, Noemi, Awwad, Noor Al-Deen, Ali, Nora, Hielscher, Nora, Trabulsi, Nora, Hüser, Norbert, Muñoz Montes, Norberto, Eshak, Norma-Sol, Rajab, Nosaiba, Lahnaoui, Nouhaila, Ouachou, Nouhaila, Ali, Nour, Dadoush, Nour, Fazili, Noureen, Theophile, Ntahompagaze, Ntanzi, Ntuthuko, Bibila, Nubia Samuel, Alwaer, Nuhay, Naabo, Nuhu, Jiagge, Nuna, Freitas Oliveira, Nuno Miguel, Pratas, Nuno, Morricone, Nunzia, Franco, Nunzio Francesco, Binti Yusri, Nur Aima, Ramli, Nur Natasya, Abd Ghani, Nur Suriyana, Umar, Nura, Aly, Nuran Khaled, Lakhanov, Nurgali, Al-Hroub, Nurhan, Kiziltoprak, Nurhilal, Chavarrias, Nuria, Maulenov, Nurlan, Akinbami, Nurudeen, Abdulraheem, Nurudeen Toyin, Karunaratne, Nuwanthika, Jeannette, Nyiransabiyera, Altobaishat, Obieda, Egwuonwu, Ochonma Amobi, Enciu, Octavian, Cohen-Arazi, Oded, Pheiffer, Odette, Okoye, Odili Aloysius, Omoike, Ofure, čančar, Ognjen, Ekwunife, Okechukwu Hyginus, Emuze, Okundayo, Eljizoly, Ola Abdallah, Al Hamdani, Ola, Emadeldeen, Ola, Morgan, Ola, Olajumoke, Oladapo, Popoola, Olakunle, Ajiboye, Olalekan, Olasehinde, Olalekan, Jolayemi, Olamide, Babatunde, Olanrewaju, Balogun, Olanrewaju, Olajide, Olawumi, Lisin, Oleg, Bellou, Olga, Jurić, Oliver, Ladlow, Oliver, Whitehurst, Oliver, Camilleri, Olivia, Montaño Angeles, Olivia, Pryer, Olivia, Ray, Olivia, Gabom, Olivier, Ndizeye, Olivier, Ojewuyi, Olufemi, Oluyemi, Olukayode, Elebute, Olumide, Ogunsua, Oluseyi, Fasiku, Olushola Kayode, Fasoro, Olusola, Fatudimu, Oluwafemi, Osunlusi, Oluwafemi, Owolanke, Oluwagbenga, Oso, Oluwarotimi, Alaba, Oluwaseun, Ojo, Oluwaseun, Oluseye, Oluwaseun, Oyinloye, Oluwaseun, Al Alyani, Omaima, Okrah, Omane, Agha, Omar, Al-Fahel, Omar, Almomani, Omar, Alruwaili, Omar, Ibarra, Omar, Ibrahim, Omar, Khalil, Omar, Kouli, Omar, Lima Azurdia, Omar, Mansour, Omar, Mohamed Mokbel, Omar, Omar, Omar, Bedak, Omer, Ozkan, Omer Faruk, Yalkın, Omer, Mohamed, Omnia, Ayandipo, Omobolaji, Faboya, Omolara, Williams, Omolara Modupe, Irowa, Omorodion, Attawodi, Onuche, Salako, Opeyemi, Ioannidis, Orestis, Agcaoglu, Orhan, Martin Sole, Oriol, Webster, Orla, Abouhiekal, Osama, Al Shaqran, Osama, Bahsas-Zaky, Osama, Nubi, Osama Gamal, Hany, Osama, Matar, Osama, Mahafdah, Osama R., Sarhan, Osama, Osagie, Osasumwen, Soublett Rivas, Óscar Alexander, Gülcicek, Osman Bilgin, Cuenca Torres, Osmar Manuel, Carpineto Samorani, Osvaldo, Arsalan, Othman, Coyoy-Gaitán, Otto, Nouhail, Oumaima, Boujidi, Oumama, Dicko, Ousmane A A, Ahmad, Owais, Christianah, Oyegbola, Küpçüoğlu, Özge, Zanbak Mutlu, Özgecan Pırıl, Chadha, P, Prabhu, P Santosh, Carmignani, Pablo, Arteaga Asensio, Pablo Cesar, Del Val Ruiz, Pablo, Royo Dachary, Pablo, Sancho Pardo, Pablo, Vásquez, Pablo, Sukhvibul, Pakkapol, Assouto, Pamphile, Evangelou, Panagiota, Dorovinis, Panagiotis, Kapsampelis, Panagiotis, Kokoropoulos, Panagiotis, Kostoglou, Panagiotis, Manikis, Panagiotis, Sakarellos, Panagiotis, Lykoudis, Panagis, Kumar, Pankaj, Patel, Panna, Paraskeva, Panoraia, Vassiliu, Panteleimon, Antonakis, Pantelis, De Nardi, Paola, Marongiu, Paola, Kamenova, Paolina, Venturelli, Paolina, Belotti, Paolo, Ubiali, Paolo, Grivas, Paraskevas, Stamopoulos, Paraskevas, Chatzikomnitsa, Paraskevi, Trakosari, Paraskevi, Tekam Wadje, Parfait Stéphane, Manjunath, Parikshith, Gupta, Pariza, Dhamija, Parth, Haque, Parvez, Haque, Parvez David, Haque, Parwez Waseemul, Nze Obiang, Pascal Christian, Probst, Pascal, Chiacchio, Pasquale, Cianci, Pasquale, Favoriti, Pasqualino, Koggoh, Patience, Bernardo, Patrícia, Omwansa, Patricia, Serrano Méndez, Patricia, Owens, Patrick, Tang, Patrick, Walker, Patrick, Chimezie Andrew, Paul, Trinity, Paul, Wilson, Paul, George, Paul Yohan, Artigot, Paula, Devlin, Paula, Vladova, Paulina, Cabrera Rivera, Paulo Andrés, Arunachalam, Pavai, Glushkov, Pavel, Levíček, Pavel, Lal, Pawanindra, Panahi, Pedram, David Santos, Pedro, Laranjo, Pedro, Palazon Bellver, Pedro, Rego Ponte, Pedro, Salas Núñez, Pedro, Sornoza, Pedro, Chloropoulou, Pelagia, Correia, Penélope, Limani, Perparim, Agbonrofo, Peter, Boateng, Peter Agyekum, Elemile, Peter, Francúz, Peter, Riedl, Peter, Tschann, Peter, Yuide, Peter, Hudáč, Petr, Ostruszka, Petr, Zimmermann, Petra, Nambala, Petrus, Shimbulu, Petrus, Thomas, Phebey A, Kumassah, Philemon, Alexander, Philip, Mensah, Philip, Taah-Amoako, Philip, Horvath, Philipp, Garcia-Dubus, Philippe, Holt, Phillip, Lapolla, Pierfrancesco, Cicerchia, Pierfranco Maria, Palumbo, Piergaspare, Anoldo, Pietro, Calò, Pietro Giorgio, Grondona, Pietro, Masseria, Pietro, Riva, Pietro, Milewski, Piotr Jan, Kowalewski, Piotr, Kasetsermwiriya, Pohpdham, Patel, Poojan, Leungon, Poramet, Kaur, Prabhjot, Arya, Prafull Kumar, Shivashankar, Pranav, Kothari, Prashant, Dummala, Prashanth, Shukla, Prateek, John, Pravin, Adebayo, Precious, Andrejevic, Predrag, Thambi, Prem, Anandan, Premkumar, Idjerhe, Prince, Boateng, Prince Kwame, Ntem, Prince, Waghchoure, Prince, Yeboah Owusu, Prince, Moodley, Priyanka, Suresh, Priyanka, Kanavidis, Prodromos, Odigie, Vincent, Christodoulou, Prokopis, Nashidengo, Pueya Rashid, Patel, Puja, Dolatzay, Qayom Khan, Mashlah, Qusai, Sabbah, Qutaiba, Sethi, R, Robitsek, R. Jonathan, Jubran, Ra'Ed, Raheem Attallah Al-obaidy, Raad, Michael, Rabha, Abela, Rachel, Colbran, Rachel, Geow, Rachel, Titcombe, Rachel, Soglonou, Rachelle, Ait Ben Addi, Rachid, Jayakrishnan, Radhakrishnan, Acharya, Radhika, Salim, Radhwan, Guzmán Lambert, Radisnay, Donchev, Radoslav, Drasovean, Radu, Andreou, Rafael, Perez-Soto, Rafael Humberto, Santana Ortiz, Rafael, Villalobos Mori, Rafael, Sokratous, Rafailia, Smolinski Kurek, Rafal Ludwik, Solecki, Rafal, Basile, Raffaele, Abd Elkareem, Raghad, Yousef Yassin, Raghad, Faisal, Raghdah, Abd Alkareem, Rahaf, Hegy, Rahma, Jaba'Teh, Rahmah, Sharma, Rahul Deo, Gupta, Rahul, Saxena, Rahul, Sinha, Rahul, Varshney, Rahul, Ripoll I Palmés, Raimon, Lunevicius, Raimundas, Raghunath, Rajat, Redkar, Rajeev, Sharma, Rajeev, Philip Sridhar, Rajeevan, Krishna Raj, Rajesh, Nathani, Rajesh, Kottayasamy Seenivasagam, Rajkumar, Ahmed, Rakesh, Handa, Rakesh, Vakil, Rakesh, Armah, Ralph, Attaf, Ram, Elazary, Ram, Alkhatib, Rama, Alzu'Bi, Rama, Raddad, Rama, Kaur, Ramanjot, Kaur, Ramanpreet, Nataraja, Ramesh, Hussam Yacoub Hattar, Ramez, Ben Hmida, Rami, Chaudhary, Ramkaran, Ramirez Calas, Ramon Andres, Soliva Domínguez, Ramón, Ghaleb, Ramzi, Batir, Rana, Haddad, Rana, Sugair, Rana, Suleiman, Rand, Perera, Ranga, Altayargh, Rania, Joumaa, Ranim, Ellawala, Ranjith, Elaifia, Rany, Eloka, Raphael, Hernandez Rodriguez, Raquel Angelica, Diaz, Raquel, Lalanda, Raquel, Rodríguez-Uria, Raquel, Olatunji, Rasheed, Wani, Rauf, Díaz Pedrero, Raúl, Ubiñas, Raul, Lertnamvongwan, Raunika, Hiary, Rawan, Almahadin, Rawan Khalid Za'al, Radwan, Rawan, Issa, Rawand, Dar, Rayees Ahmad, Nyirenda, Raymond, Eghonghon, Raymond Atah, Oppong, Raymond, Govindaraju, Rayshini, Kalouk, Razan, Abad, Rebeca, Akankoatuesi Apatewen, Rebecca, Bradley, Rebecca, Enejo, Rebecca Eboshogwe, Hauwa Sani, Rebecca, Jurdon, Rebecca, Sönmez, Recep Erçin, Belouz, Reda, Abhinaya, Reddy, Abu Salah, Reem, Alatawi, Reem, Alqahtani, Reem, Sayad, Reem, Adel Diab, Rehab, Függer, Reinhold, Madi, Reman, Pajtak, Renata, Barradas, Renato, Díaz-Ruiz, Renato, Patrone, Renato, Palacios Huatuco, René M., Casma Bustamante, Renzo, Ranadive, Reuben Rajappa, Askari, Reza, Sulce, Rezart, Liang, Rhea, Tummon, Rhea, Roberts, Rhianna, Mcclen, Rhys, Duvenage, Riaan, Kattini, Ribal, Alvarado Hurtado, Ricardo, Tenfen Carneiro, Ricardo Augusto, Castro Lara, Ricardo Jesús, Silva Borges, Ricardo, Souto, Ricardo, Vaz Pereira, Ricardo, Barone, Riccardo, Fratarcangeli, Riccardo, Guercio, Riccardo, Magarini, Riccardo, Malatesti, Riccardo, Tripathi, Richa, Crawford, Richard, Kpangkpari, Richard, Marlin, Richard, McGee, Richard, Nesco, Richard, Spence, Richard, Akpaka, Richfield, Alinde, Rigobert, Khalid, Rija, Sato, Rikiya, Kitamura, Riley, Baldan, Rino, Agyei Boakye, Rita, Branquinho, Rita, Hleyhel, Rita, Miranda Pera, Rita, Pinheiro Duque, Rita, Ribeiro Dias, Rita, Bhatia, Riya, Rabah, Rnad, Damseh, Ro'Ya, Alzughayyar, Roa, Daradkeh, Roa'A, Bassam, Roaa, Refaie, Roaa, Bethune, Rob, Elshennawy, Roba, Cachia, Robert, Franz, Robert, Grützmann, Robert, Kibuuka, Robert, Laskowski, Robert, Mazurkiewicz, Robert, Munyaneza, Robert, Parker, Robert, Sagoe, Robert, Sucher, Robert, Granata, Roberta, Ruccella, Roberta, Tutino, Roberta, Badra, Roberto, Mares País, Roberto, Sampietro, Roberto, Scola, Roberto, Mackay, Robyn, Tumolo, Rocco, Figueroa, Rodrigo, Doamba, Rodrigue, Habib, Rohan, Gujjuri, Rohan R, Anjum T Siddeek, Rohik, Mittal, Rohin, Kumar, Rohit, Goudou, Roland, Rüdrich, Roland, Senin, Roman, Moukarzel, Romika, Ferlini, Romina Lorena, Ribeiro, Rómulo, Schmidt-Branden, Romy, Zerna Encalada, Ronald, Ferreira Acosta, Rosa, Lopatriello, Rosanna, Perez, Rosario, Hall, Rosie, Alloni, Rossana, Arena, Rossella, Gioco, Rossella, Polo, Roxy, Shen, Ru, Doherty, Ruairi, Rivas, Ruben, Oppong-Amoah, Ruby, Ooi, Rucira, Radojković, Rudolf, Herrera, Rudy, Bernardino, Rui, Ediru, Rukevwe, Al Shehhi, Ruqaiya, Masri, Ruqaya, Hodgson, Russell, Azimov, Rustam, Martínez Díaz, Rut, Santos Pereira, Rute, Naidoo, Ruvashni, Noor, Ruzaimie, Campbell, Ryan, Khalil, Ryta, Chigblo, S. 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Sharitha, Laura, Sharon, Shanker, Shashwat, Ababneh, Shatha, Gilbert, Shaun, Kenworthy, Shaunna, Ng, Shawn Hong Ming, Mackenzie, Shawn, Salindera, Shehnarz, Khattak, Shehrbano, Loke, Sheih Nee, Manzoor, Sheikh Viqar, Alwardi, Sheikha, Allam, Shereen, Tawfik, Sherifa, Francis, Shikha, Cai, Shirley, Dindyal, Shiva, Pandya, Shivangi, Chopra, Shreya, Ingley, Shreya, Kulkarni, Shrirang, Kosna, Shuba, Nayak, Shubhalaxmi, Ahuja, Shubham, Hariharan, Shubhang, Karuppusamy Krishnasamy, Shyam, Khare, Siddhant, Handa, Siddhartha, Amin Omar Alsiddig, Siddig, Alqurashi, Siddiga, Al-Tahayneh, Sief-Addeen, Sibiya, Silindokuhle, Perretta, Silvana, Ibarra Camargo, Silvia Alejandra, Montisci, Silvia, Mungo, Silvia, Puddu, Silvia, Severi, Silvia, Agudelo Mendoza, Silvia Valentina, Makkai-Popa, Silviu Tiberiu, Boyes, Simon, Monkhouse, Simon, Stock, simon, Alberti, Simona, Meneghini, Simona, Giudici, Simone, Guadagni, Simone, Birolo, Simone Lorenzo, Novello, Simone, Oliveira, Simone, Gumede, Simphiwe, Dhole, Simran, Budhwani, Simran Saleem, Ramjit, Sinead, Yumurtacilar, Sinem, Mahendra, Sirigi Naga, Abeykoon, Sithira, Moh Pauzi, Siti Farhan, Rajendra, Sittampalam, Sundararajan, Siva, Gananadha, Sivakumar, Kamarajah, Sivesh K, Marawu, Siyasanga, Basu, Sk, Hassan, Sleman, Reddy, Snigdha Mettu, Anaya Sanchez, Sofia, Gaspar Reis, Sofia, Gomez, Sofía, Gamba, Sofia Lucia, Pimentel Morais, Sofia, Ashry, Soha, Abdullateef, Sohaila, Bandyopadhyay, Soham, Samadi, Soheil, Pathan, Sohilkhan R., Lakew, Solomon, Basu, Somprakas, Ohri, Sonali, Alonso Marcos, Sonia, Amoza Pais, Sonia, Fortuna Martins, Sónia, Gill, Sonia, Matthiess, Sonia, Sabbatini, Sonia, Soto Schütte, Sonia, Engel, Sophie, Eam, Sothseyhakmonique, Botaitis, Sotirios, Lawani, Souliath, Jamil, Soumaya, Kondpan, Sourav, Oum, Sovannarith, Govender, Sovishnee, Christodoulou, Spyridon, Davakis, Spyridon, Vernadakis, Spyridon, Gkogkos, Spyros, Gobishangar, Sreekanthan, Suresh, Sreelakshmi, Vembar, Sridhar, M, Srikanth, Abdelrasoul Elnour Ismail, Srraa, Zourntou, Stamatina-Emmanouela, Nwabuoku, Stanley Emeka, Ideh, Stanley, Charitonos, Stavria, Liapis, Stavros Chrysovalantis, Faber, Stefan, Piccioni, Stefania Angela, Romano, Stefania, Silvestre, Stefania, Jarmusch, Stefanie, Soelling, Stefanie, Cardelli, Stefano, Chaifouroosh Mamagany, Stefano, Corso, Stefano, Basso, Stefano Maria Massimiliano, Megna, Stefano, Bitsianis, Stefanos, Tsatsos, Stefanos, Morales, Steffanía, Gerdes, Stephan, Göller, Stephanie, Hanna, Stephanie, Tabiri, Stephen, Agana, Stephen, Theivendran, Stephen Arthur, Kache, Stephen, Knight, Stephen R, Smith, Stephen, Stonelake, Stephen, Wrenn, Stephen, Gopaul, Steven, Vederaki, Styliani, Kapiris, Stylianos, Kykalos, Stylianos, Hlaing, Su Su, Chia, Su Yin Denise, Abu Khousa, Suad, M. Udwan, Suad, Raul, Subrat, Chase, Suchita, Nair, Sudharrshan, Joseph, Sudhir, Singh, Sudhir Kumar, Singh, Sudhir, Timmalah, Suhaylah, Alsuwiyah, Suhir, Thalgaspitiya, Sujeewa Priyantha Bandara, Sellahewa, Sujeewa, Neogi, Sujoy, Burger, Sule, Polat, Süleyman, Alkadi, Sulman, Asiri, Sultan, Otho, Sumaira, Mewa Kinoo, Suman, Ebrahim, Sumayyah, Tontus, Sumeyya, Midya, Sumit, Thuraisamy Sarma, Sundaramoorthy Iyer, Payyanur Thotan, Sundeep, Kumar Venkatappa, Sunil, Techapongsatorn, Suphakarn, Kaur, Supreet, Jp, Supritha, Tan, Suqi, Djote, Surafel Mulatu, Surendran, Suraj, Singh, Surendra, Chilaka, Suresh, Lee, Susan, Henriques, Susana, Giridaran, Suseendirarajah, Achugatla, Sushma, Kumar, Suvam, Brincat, Svetlana, Deshpande, Swati, Batista, Sylvia, Akharaekpanya, Tachporn, Moges, Tadesse Girma, Türkmen, Taha Berkay, Alhaj Hasan, Taima, Alshawabkeh, Taima', Majed, Taima', Lawal, Taiwo Akeem, Ibiyeye, Taiye Taibat, Rashid, Tajamul, Košir Božič, Tajda, Mohammed, Tajudeen, Khewater, Talal, Abelman, Talia, Al Barhi, Tamadher, Mogne, Tamiris, Salazar-Lorenzana, Tania Abril, Akter, Tania, Gómez Sanz, Tania, Motiwala, Tanmay, Valizadeh Elizeh, Tanya, Almahdi, Tanzeel, Albushary, Tanzel Alrahman, Abdulrahman, Taofeeq, Finlay, Tara, Chouari, Tarak, Awad, Tarek, Sabra, Tarek, M. Abubasheer, Tareq, Alhusban, Tariq, Yılmaz, Tarık Emre, Aloqaili, Tasneem, Aldirawi, Tayef, Karahasanoğlu, Tayfun, Gülşen, Taygun, Jemal, Tebarek, Nadeem, Tehmina, Singh, Tejinder Paul, Alinger, Temsula, Longkumer, Temsutoshi, Lo, Terence, Gimenez Maurel, Teresa, Uprak, Tevfik Kıvılcım, Petropoulou, Thalia, Rawther, Thampi, Techapongsatorn, Thawin, Manickam, Thendral, Padioti, Theodora, Kozonis, Theodoros, Sidiropoulos, Theodoros, Tsirlis, Theodoros, Theodosopoulos, Theodosios, Hessou, Thierry Kinnongni, Uiyapat, Thitapon, Agyen, Thomas, Harris, Thomas, Hugh, Thomas J, Jorgensen, Thomas W., Theivendrampillai, Thrshegan, Pham, Thuy Vy, Branco, Tiago, Nagwamutse, Tijjani Nasiru, Tony V, Tina, Devabalan Koil, Titus, Pilia, Tiziana, Abdulmola, Tmador Mahmed Ali, Oyeyemi, Tobiloba, Kebede, Tolera, Ibarra-Hurtado, Tomás Ramón, Reichelt, Tomas, Gach, Tomasz, Stefura, Tomasz, Wojewoda, Tomasz, Soric, Tomislav, Risteski, Toni, Tridip, Tridip Dutta Baruah, Yotsov, Tsanko, Doma Bhutia, Tshering, Girma, Tsion, Kwan, Tsun Yu, Ivanov, Tsvetomir, Iahmo, TT, Ashkar, Tuleen, Mabogoane, Tumi, Olobatoke, Tunde, Sholadoye, Tunde T., Mishra, Tushar Subhadarshan, Parker, Tyla, Ezomike, Uchechukwu, Dilibe, Uchenna, Kumbhar, Uday, Una, Uduak-Abasi, Grossi, Ugo, Ezidiegwu, Ugochukwu, Edith, Ugwuoke, Daspal, Ujjwal, Kalu, Ukoha Agwu, Dietz, Ulrich, Ronellenfitsch, Ulrich, Wirth, Ulrich, Abdullah, Umar, Rivolta, Umberto, Jayarajah, Umesh, Kanyan Kassim, Umu-Hera, Govindan, Unnikrishnan, Fernandes, Urânia, Akram, Usman, Mohammed Bello, Usman, Omara, Usra, Naidoo, Uvarasen, Mahendravarman, Vaishnaivy, Negoita, Valentina Madalina, Mariottini, Valentina, Murzi, Valentina, Zucchini, Valentina, Agbakwuru, Valentine, Armenta Tapia, Valeria Estefania, Gentilino, Valerio, Borgogni, Vanessa, Ng, Vanessa, Wolfschluckner, Vanessa, Silvestri, Vania, Žufić, Vanja, Gunasaegaram, Varman, Kamalathevan, Vasan, Pillay, Vasanthan, Neykov, Vasil, Kalles, Vasileios, Mousafeiris, Vasileios, Papadopoulos, Vasileios, Tsaousis, Vasileios, Tselepidis, Vasileios, Vougas, Vasileios, Georgilaki, Vasiliki, Nikolaou, Vasiliki, Themelidi, Vasiliki, Manchev, Vassil, Ioannou, Veatriki, Jha, Vedant Shekhar, Dragisic, Vedran, Sutharshan, Vengadasalam, Alonso, Veronica, Brocco, Veronica, Ongil Rodríguez, Verónica, Schirinzi, Veronica, Budyakova, Veronika, Naunova, Vesna, Panduro-Correa, Vicky, Ruiz López, Víctor Andrés, Bill, Victor, Dassah, Victor, Gonzabay, Víctor Eduardo, Etwire, Victor, Modekwe, Victor, Serna-Alarcon, Victor, De Donato, Victor Ugo, Duque Mallén, Victoria, Liu, Victoria, Sharma, Vidushi, Kumar, Vijaya, Muralidharan, Vijayaragavan, Kakotkin, Viktor, Enemuo, Vincent, Kudoh, Vincent, Osoka, Vincent, Siepaal, Vincent, Granata, Vincenza, Dinuzzi, Vincenza Paola, Lizzi, Vincenzo, Ricchiuti, Vincenzo, Mosca, Vinicio, Kanna D, Vinoth, Nair, Vipin Venugopal, Ledda, Virginia, Michael, Vishal, Singh, Vishavdeep, Govindasamy, Vishendran, Kollengode, Viswanathan V, Giordano, Vittoria, Morinelli, Vittoria, Lin, Vivian, Cuk, Vladica, Cijan, Vladimir, Çalik, Volkan, Bakshi, Vrushank, Ten, Vyacheslav, Ratheesh, Vysakh, Alsado, Wael, Mayo, Wafik, Yang, Wah, Rehman, Wajeeh Ur, Abbas, Walaa, Al-Khyatt, Waleed, Mabood, Waleed, Santucci, Walter, Yew, Wan Ting, Tahir, Warda, De Silva, Warusha Dhammika Dulantha, Wijenayake, Wasantha, Almadhoun, Waseem J.N., Alhroub, Wasef, Ebrahim, Wesam, Jabłoński, Wiktor, Krawczyk, Wiktor, Bhatti, William, Lai, William Kwan Ho, Petrushnko, Wilson, Afedo, Wisdom, Kasetsermwiriya, Wisit, Serednicki, Wojciech, Wysocki, Wojciech, Zerefa, Wondwossen Amtataw, Vagena, Xanthoula, Tarrado, Xavier, Papazarkadas, Xenofon, Po, Xiang Yuen, Ouadi, Yacine, Myla, Yacob, Haido, Yacoub, Hasan, Yafea, Karataş, Yağmur, Carpio Colmenares, Yahaira, Galvañ Félix, Yaiza, Balogun, Yakub Lekan, Maktabi, Yaman, Nerabani, Yaman, Fulgence, Yamuremye, De Silva, Yannick, Asar, Yara, Samer Morsy, Yara, Ghaleb, Yasameen Saif Saeed Mohammed, Vashishth, Yash, M S, Yashas, Manickchund, Yashoda, Sakaray, Yashwant, Kara, Yasin, Tosun, Yasin, Zwain, Yasir, Farag, Yasmeen, Jedidi, Yasmine, Seada, Yasmine, Aldebasi, Yasser, Ashour, Yasser, Badr, Yassin, Sarpong, Yaw, Alawneh, Yazan, Aung, Yee Lay, Orabi, Yehia, Lam, Yick Ho, Şen, Yigit Kaan, Koyluoglu, Yilmaz Onat, Huang, Yining, Mintz, Yoav, Perez, Yocarli, Chamara, Yohan, Melkamu, Yohannes, Maestre González, Yolanda, Dean, Yomna, Metaferia, Yonas Yilma, Malki, Yosra, Mohamed, Younis, A. Omar, Yousef, Alhammoud, Yousef, Allaoua, Yousef, Tanas, Yousef, El Okazy, Youssef, Kerolous, Youssef, Mohamed, Youssef, Al-Junaidi, Youssuf, Lakdawala, Yousuf, Lu, Yuann, Asano, Yukio, Altinel, Yuksel, Aktimur, Yunus Emre, Fishman, Yuri, Kudryavcev, Yurii, Tandoğan, Yusuf Iskender, Razafimandimby, Yves Michaël, Adofo-Asamoah, Yvonne, Şenol, Zafer, Odeh, Zahra, Benamrouche, Zahra Rayane, Alkhaier, Zahraa, Al-Sheikh Ali, Zaid, Zaher, Zain Aldin, Alnajjar, Zaina, Al-Balushi, Zainab, Alkhuzaie, Zainab, Khraim, Zakaria, Toutounji, Zakaria, Djama, Zakarya, Farraj, Zamil, Shah, Zamir Ahmad, Khan, Zara, Khan, Zarnigar, Abo Alarous, Zayn Alabden, Asaad, Zaynab, Demetrashvili, Zaza, Lorenc, Zbigniew, Brekalo, Zdrinko, Hannouneh, Zein Alabdin, Robertson, Zelda, Bady, Zeyad, Durna, Zeynep, Wong, Zhen Yu, Fozo, Zien Alabdin, Klib, Zienab, Chin, Ziling, Tamou, Zime Farid, Johnson, Zina, Shabello, Ziyad, Orzeszko, Zofia, Aljalabi, Zohal, Al-Azher El-Hamel, Zohour, Karampotaki, Zoi Rafaila, Valera Sanchez, Zoraida, Matkovic, Zoran, Azhar, Zubair, Qureshi, Zubaria, Correa López, Zulema Margarita, Balciscueta, Zutoia, Musilová, Zuzana, Katusic, Zvonimir, Osama, Zyad, and Dauksa, Zygimantas

Published
2024
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25. Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats

Author

Michael-Alexander Pais, Athanasios Papanikolaou, Isabel Arenas Hoyos, Robert Nißler, Simone De Brot, Alexander Gogos, Robert Rieben, Mihai A. Constantinescu, Martin T. Matter, Inge K. Herrmann, and Ioana Lese

Subjects
seroma formation, bioglass/ceria nanoparticle hybrids, animal rat model, anti-inflammatory response of nanoparticles, adhesive properties of nanoparticles, Biotechnology, TP248.13-248.65
Abstract

Background: Seroma formation is a common postoperative complication. Fibrin-based glues are typically employed in an attempt to seal the cavity. Recently, the first nanoparticle (NP)-based treatment approaches have emerged. Nanoparticle dispersions can be used as tissue glues, capitalizing on a phenomenon known as ‘nanobridging’. In this process, macromolecules such as proteins physically adsorb onto the NP surface, leading to macroscopic adhesion. Although significant early seroma reduction has been shown, little is known about long-term efficacy of NPs. The aim of this study was to assess the long-term effects of NPs in reducing seroma formation, and to understand their underlying mechanism.Methods: Seroma was surgically induced bilaterally in 20 Lewis rats. On postoperative day (POD) 7, seromas were aspirated on both sides. In 10 rats, one side was treated with NPs, while the contralateral side received only NP carrier solution. In the other 10 rats, one side was treated with fibrin glue, while the other was left untreated. Seroma fluid, blood and tissue samples were obtained at defined time points. Biochemical, histopathological and immunohistochemical assessments were made.Results: NP-treated sides showed no macroscopically visible seroma formation after application on POD 7, in stark contrast to the fibrin-treated sides, where 60% of the rats had seromas on POD 14, and 50% on POD 21. At the endpoint (POD 42), sides treated with nanoparticles (NPs) exhibited significant macroscopic differences compared to other groups, including the absence of a cavity, and increased fibrous adhesions. Histologically, there were more macrophage groupings and collagen type 1 (COL1) deposits in the superficial capsule on NP-treated sides.Conclusion: NPs not only significantly reduced early manifestations of seroma and demonstrated an anti-inflammatory response, but they also led to increased adhesion formation over the long term, suggesting a decreased risk of seroma recurrence. These findings highlight both the adhesive properties of NPs and their potential for clinical therapy.

Published
2024
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26. Altered corollary discharge signaling in the auditory cortex of a mouse model of schizophrenia predisposition

Author

Brian P. Rummell, Solmaz Bikas, Susanne S. Babl, Joseph A. Gogos, and Torfi Sigurdsson

Subjects
Science
Abstract

Abstract The ability to distinguish sensations that are self-generated from those caused by external events is disrupted in schizophrenia patients. However, the neural circuit abnormalities underlying this sensory impairment and its relationship to the risk factors for the disease is not well understood. To address this, we examined the processing of self-generated sounds in male Df(16)A +/− mice, which model one of the largest genetic risk factors for schizophrenia, the 22q11.2 microdeletion. We find that auditory cortical neurons in Df(16)A +/− mice fail to attenuate their responses to self-generated sounds, recapitulating deficits seen in schizophrenia patients. Notably, the auditory cortex of Df(16)A +/− mice displayed weaker motor-related signals and received fewer inputs from the motor cortex, suggesting an anatomical basis underlying the sensory deficit. These results provide insights into the mechanisms by which a major genetic risk factor for schizophrenia disrupts the top-down processing of sensory information.

Published
2023
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27. Development and internal validation of a clinical prediction model for serious complications after emergency laparotomy

Author

Kokkinakis, Stamatios, Kritsotakis, Evangelos I., Paterakis, Konstantinos, Karali, Garyfallia-Apostolia, Malikides, Vironas, Kyprianou, Anna, Papalexandraki, Melina, Anastasiadis, Charalampos S., Zoras, Odysseas, Drakos, Nikolas, Kehagias, Ioannis, Kehagias, Dimitrios, Gouvas, Nikolaos, Kokkinos, Georgios, Pozotou, Ioanna, Papatheodorou, Panayiotis, Frantzeskou, Kyriakos, Schizas, Dimitrios, Syllaios, Athanasios, Palios, Ifaistion M., Nastos, Konstantinos, Perdikaris, Markos, Michalopoulos, Nikolaos V., Margaris, Ioannis, Lolis, Evangelos, Dimopoulou, Georgia, Panagiotou, Dimitrios, Nikolaou, Vasiliki, Glantzounis, Georgios K., Pappas-Gogos, George, Tepelenis, Kostas, Zacharioudakis, Georgios, Tsaramanidis, Savvas, Patsarikas, Ioannis, Stylianidis, Georgios, Giannos, Georgios, Karanikas, Michail, Kofina, Konstantinia, Markou, Markos, Chrysos, Emmanuel, and Lasithiotakis, Konstantinos

Published
2024
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30. Reducing complication rates for repeat craniotomies in glioma patients: a single-surgeon experience and comparison with the literature

Author

Morshed, Ramin A, Young, Jacob S, Gogos, Andrew J, Haddad, Alexander F, McMahon, James T, Molinaro, Annette M, Sudhakar, Vivek, Al-Adli, Nadeem, Hervey-Jumper, Shawn L, and Berger, Mitchel S

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Rare Diseases, Brain Disorders, Neurosciences, Clinical Research, Cancer, Brain Neoplasms, Craniotomy, Glioma, Humans, Postoperative Complications, Retrospective Studies, Surgeons, Treatment Outcome, Complications, Recurrence, Surgical resection, Neurology & Neurosurgery, Clinical sciences
Abstract

BackgroundThere is a concern that glioma patients undergoing repeat craniotomies are more prone to complications. The study's goal was to assess if the complication profiles for initial and repeat craniotomies were similar, to determine predictors of complications, and to compare results with those in the literature.MethodsA retrospective study was conducted of glioma patients (WHO grade II-IV) who underwent either an initial or repeat craniotomy performed by the senior author from 2012 until 2019. Complications were recorded by discharge, 30 days, and 90 days postoperatively. New neurologic deficits were recorded by 90 days postoperatively. Multivariate regression was performed to identify factors associated with complications. A meta-analysis was performed to identify rates of complications based on number of prior craniotomies.ResultsWithin the cohort of 714 patients, 400 (56%) had no prior craniotomies, 218 (30.5%) had undergone 1 prior craniotomy, and 96 (13.5%) had undergone ≥ 2 prior craniotomies. There were 27 surgical and 10 medical complications in 30 patients (4.2%) and 19 reoperations for complications in 19 patients (2.7%) with no deaths by 90 days. Complications, reoperation rates, and new neurologic deficits did not differ based on number of prior craniotomies. On multivariate analysis, older age (OR1.5, 95%CI 1.0-2.2) and significant leukocytosis due to steroid use (OR12.6, 95%CI 2.5-62.9) were predictors of complications. Complication rates in the cohort were lower than rates reported in the literature.ConclusionContrary to prior reports in the literature, repeat craniotomies can be as safe as initial operations if surgeons implement best practices.

Published
2022

31. Patterns, Outcomes and Economic Burden of Primary vs. Secondary Bloodstream Infections: A Single Center, Cross-Sectional Study

Author

Ioannis Chandroulis, Georgios Schinas, Anne-Lise de Lastic, Eleni Polyzou, Stamatia Tsoupra, Christos Davoulos, Martha Kolosaka, Vasiliki Niarou, Spyridoula Theodoraki, Dimitrios Ziazias, Foteini Kosmopoulou, Christina-Panagiota Koutsouri, Charalambos Gogos, and Karolina Akinosoglou

Subjects
bloodstream infections, bacteremia, primary bacteremia, secondary bacteremia, clinical outcomes, mortality, Medicine
Abstract

Bloodstream infections (BSIs) can be primary or secondary, with significant associated morbidity and mortality. Primary bloodstream infections (BSIs) are defined as infections where no clear infection source is identified, while secondary BSIs originate from a localized infection site. This study aims to compare patterns, outcomes, and medical costs between primary and secondary BSIs and identify associated factors. Conducted at the University Hospital of Patras, Greece, from May 2016 to May 2018, this single-center retrospective cohort study included 201 patients with confirmed BSIs based on positive blood cultures. Data on patient characteristics, clinical outcomes, hospitalization costs, and laboratory parameters were analyzed using appropriate statistical methods. Primary BSIs occurred in 22.89% (46 patients), while secondary BSIs occurred in 77.11% (155 patients). Primary BSI patients were younger and predominantly nosocomial, whereas secondary BSI was mostly community-acquired. Clinical severity scores (SOFA, APACHE II, SAPS, and qPitt) were significantly higher in primary compared to secondary BSI. The median hospital stay was longer for primary BSI (21 vs. 12 days, p < 0.001). Although not statistically significant, mortality rates were higher in primary BSI (43.24% vs. 26.09%). Total care costs were significantly higher for primary BSI (EUR 4388.3 vs. EUR 2530.25, p = 0.016), driven by longer hospital stays and increased antibiotic costs. This study underscores the distinct clinical and economic challenges of primary versus secondary BSI and emphasizes the need for prompt diagnosis and tailored antimicrobial therapy. Further research should focus on developing specific management guidelines for primary BSI and exploring interventions to reduce BSI burden across healthcare settings.

Published
2024
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32. SARS-CoV-2 Variants and Clinical Outcomes of Special Populations: A Scoping Review of the Literature

Author

Achilleas Livieratos, Charalambos Gogos, and Karolina Akinosoglou

Subjects
SARS-CoV-2 variants, clinical outcomes, immunocompromised, HIV, pediatric, chronic liver disease, Microbiology, QR1-502
Abstract

The ongoing COVID-19 pandemic has significantly impacted special populations, including immunocompromised individuals, people living with HIV (PLWHIV), pediatric patients, and those with chronic liver disease (CLD). This scoping review aims to map the clinical outcomes of these vulnerable groups when infected with various SARS-CoV-2 variants. The review identifies trends and patterns, noting that early variants, such as Alpha and Delta, are associated with more severe outcomes, including higher hospitalization and mortality rates. In contrast, the Omicron variant, despite its increased transmissibility, tends to cause milder clinical manifestations. The review highlights the necessity for ongoing surveillance and tailored healthcare interventions due to the heterogeneity of patient populations and the evolving nature of the virus. Continuous monitoring and adaptive healthcare strategies are essential to mitigate the impact of COVID-19 on these high-risk groups.

Published
2024
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33. Right Ventricular and Right Atrial Strain Are Associated with Kidney Dysfunction in Acute Heart Failure

Author

Vasileios Anastasiou, Emmanouela Peteinidou, Christos Tountas, Stylianos Daios, Dimitrios V. Moysidis, Emmanouil Fardoulis, Christos Gogos, Marieta Theodorakopoulou, Fotini Iatridi, Pantelis Sarafidis, George Giannakoulas, Theodoros Karamitsos, Victoria Delgado, Antonios Ziakas, and Vasileios Kamperidis

Subjects
acute heart failure, renal impairment, increased renal afterload, right ventricular strain, right atrial strain, Medicine (General), R5-920
Abstract

Background: In acute heart failure (HF), low cardiac output and venous congestion are pathophysiological mechanisms that contribute to renal function impairment. This study investigated the association between advanced echocardiographic measures of right ventricular and atrial function and renal impairment in patients with acute HF. Methods and Results: A total of 377 patients hospitalized for acute HF were prospectively evaluated. Estimated glomerular filtration rate (eGFR) on admission was measured using the 2021 Chronic Kidney Disease Epidemiology Collaboration creatinine equation. Advanced echocardiographic assessment was performed on admission. Patients with eGFR < 45 mL/min/1.73 m2 were more likely to have chronic heart failure, chronic atrial fibrillation, and type 2 diabetes mellitus compared to patients with eGFR ≥ 45 mL/min/1.73 m2. Patients with lower eGFR had lower cardiac output, higher mean E/e’ ratio, larger right ventricular (RV) size, worse RV free wall longitudinal strain, more impaired right atrial (RA) reservoir strain, and more frequent severe tricuspid regurgitation. RV free wall longitudinal strain and RA reservoir strain were the only independent echocardiographic associates of low eGFR, whereas cardiac output was not. Conclusions: Impaired RV and RA longitudinal strain were independently associated with eGFR < 45 mL/min/1.73 m2 in acute HF, while reduced cardiac output was not. This suggests that RV and RA dysfunction underlying venous congestion and increased renal afterload are more important pathophysiological determinants of renal impairment in acute HF than reduced cardiac output.

Published
2024
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34. Testing Hepatitis E Seroprevalence among HIV-Infected Patients in Greece: The SHIP Study

Author

Nikolina Antonopoulou, Georgios Schinas, Zoi Kotsiri, Olga Tsachouridou, Konstantinos Protopapas, Vasileios Petrakis, Emmanouil C. Petrakis, Despoina Papageorgiou, Dimosthenis Tzimotoudis, Simeon Metallidis, Antonios Papadopoulos, Markos Marangos, Emmanouil Barbounakis, Diamantis P. Kofteridis, Periklis Panagopoulos, Charalambos Gogos, Apostolos Vantarakis, and Karolina Akinosoglou

Subjects
hepatitis E virus, HIV infections, coinfection, seroprevalence, Greece, antiretroviral therapy, Medicine
Abstract

Hepatitis E virus (HEV) poses significant health concerns worldwide, particularly among people living with HIV (PLWHIV), due to an increased risk of chronic infection and progression to cirrhosis in individuals with low CD4 cell counts. This study aimed to investigate the prevalence, chronicity potential, and risk factors of HEV infection among PLWHIV in Greece, where data are currently absent. A synchronic multicentric study encompassing five major Greek university hospitals was executed over 24 months, recruiting 696 PLWHIV participants. The prevalence of HEV IgG antibodies was 16.5%, with 8.6% showing evidence of acute HEV infection (HEV IgM). Active viral replication (HEV RNA) was present in 2.3% of the study population. Longitudinal analysis revealed that of the 25 initially anti-HEV IgM-positive individuals, only 3 seroconverted to IgG positivity, and among those with prior HEV RNA positivity (16), none showed evidence of active replication in subsequent tests. Comparative subgroup analysis highlighted the lack of significant differences in HIV-related parameters between HEV seropositive and seronegative individuals. Laboratory evaluations generally showed no significant disparities across most parameters; however, a higher seropositivity for Hepatitis A was observed in the HEV-positive subgroup. Our findings highlight a considerable prevalence of HEV among PLWHIV in Greece, with no observed cases of chronicity.

Published
2024
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35. Macrophage Activation Syndrome in Viral Sepsis

Author

Despoina Papageorgiou, Charalambos Gogos, and Karolina Akinosoglou

Subjects
macrophage activation syndrome, secondary hemophagocytic lymphohistiocytosis, viral infections, COVID-19, Microbiology, QR1-502
Abstract

Macrophage activation syndrome (MAS) is a life-threatening systemic hyperinflammatory syndrome triggered by various infections, particularly viral infections, autoimmune disorders, and malignancy. The condition is characterized by an increased production of proinflammatory cytokines resulting in a cytokine storm and has been associated with poor clinical outcomes. During the COVID-19 pandemic, patients with severe manifestations developed features similar to those of MAS, although these characteristics remained well defined within the lung. Additionally, other viral infections including EBV, the herpes family of viruses, hepatitis viruses, influenza, HIV, and hemorrhagic fevers can be complicated by MAS. The diagnosis and management of the condition remain challenging due to the lack of consensus on specific guidelines, especially among the adult population. Currently, therapeutic options primarily rely on medications that are typically used to treat primary hemophagocytic lymphohistiocytosis, such as corticosteroids and etoposide. In addition, cytokine-targeted therapies present promising treatment options. The objective of this review is to discuss the emergence of MAS in the context of viral infections including, but not limited to, its occurrence in COVID-19.

Published
2024
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36. Near-unity broadband omnidirectional emissivity via femtosecond laser surface processing

Author

Reicks, Andrew, Tsubaki, Alfred, Anderson, Mark, Wieseler, Jace, Khorashad, Larousse Khosravi, Shield, Jeffrey E., Gogos, George, Alexander, Dennis, Argyropoulos, Christos, and Zuhlke, Craig

Subjects
Physics - Optics
Abstract

It is very challenging to achieve near perfect absorption/emission that is both broadband and omnidirectional while utilizing a scalable fabrication process. Femtosecond laser surface processing is an emerging low-cost and large-scale manufacturing technique used to directly and permanently modify the surface properties of a material. The versatility of this technique to produce tailored surface properties has resulted in a rapidly growing number of applications. Here, we demonstrate near perfect, broadband, omnidirectional emissivity from aluminum surfaces by tuning the laser surface processing parameters including fluence, pulse count, and the ambient gas. Full-wave simulations and experimental results prove that the obtained increase in emissivity is mainly a result of two distinct features produced by femtosecond laser surface processing: the introduction of microscale surface features and the thick oxide layer. This technique leads to functionalized metallic surfaces that are ideal for emerging applications, such as passive radiative cooling and thermal management of spacecraft.

Published
2020
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39. Attributable mortality of infections caused by carbapenem-resistant Enterobacterales: results from a prospective, multinational case-control-control matched cohorts study (EURECA)

Author

Serna, Almudena de la, Monteau, Sophie, Palomo, Virginia, Soriano, Elena, Gutierrez, David, Moreno, Elisa, Sojo-Dorado, Jesus, Morales, Isabel, Maldonado, Natalia, Santis, Lucia Valiente de, Ciezar, Antonio Plata, Ruiz Mesa, Juan Diego, Diaz, Beatriz Sobrino, Gomez, Ignacio Marquez, Camacho, Ines Perez, Cano, Angela, Frutos-Adame, Azahara, Guzman-Puche, Julia, Gracia-Ahufinger, Irene, Perez-Nadales, Elena, Torre-Gimenez, Julian, Pyrpasopoulou, Athina, Iosifidis, Elias, Chorafa, Elsa, Radovanovic, Ivana, Petrovic, Sladjana, Cvetkovi, Slavica, Melentijevic, Srdjan-Sanja, Bicmen, Can, Senol, Gunes, Tubau, Fe, Camara, Jordi, Daniel Gumucio, Victor, Bassoulis, Dimitris, Deliolanis, John, Pitiriga, Vassiliki Ch., Triarides, Nikolaos, Argiti, Efstathia, Legakis, Nikolaos J., Margarita, Kyriakidou, Gijón-Cordero, Desirée, Ruiz-Garbajosa, Patricia, Rossolini, Gian Maria, Nica, Maria, Talapan, Daniela, Medić, Deana, Prijić, Sanja Maričić, Caballero, Mireia Cantero, Ramírez, Lina M Parra, Bilgin, Hüseyin, Dalekos, George N., Stefos, Aggelos, Spyridis, Nikolaos, Michos, Athanasios, De Rosa, Francesco Giuseppe, Cavallo, Rossana, Petrosillo, Nicola, Dicaro, Antonio, Landini, Maria Paola, degli Atti, Marta Luisa Ciofi, Masanovic, Mileva, Matkovic, Dusan, Tsiodras, Sotirios, Blasi, Francesco, pasquale, Marta Di, Viscoli, Claudio, Vata, Andrei, Dorneanu, Olivia, Kapisyzi, Perlat, Vince, Adriana, Tsigou, Evdoxia, Maltezos, Efstratios, Komnos, Apostolos, Gogos, Charalampos, Franzetti, Fabio, Antonelli, Massimo, Lupse, Mihaela, Corneci, Dan, Tomescu, Dana, Georgescu, Anca, Bukarica, Ljiljana, Mitrović, Goran, Krstić, Nataša Lukić, Kurti, Arsim, Reuter, Sandra, Díaz-Pollán, Beatriz, Sabater, Julia Origüen, Muñoz, Patricia, Azap, Alpay, ancak, Banu, Sahin, Arife, Akalin, Halis, Paniagua-García, María, Bravo-Ferrer, Jose M., Pérez-Galera, Salvador, Kostyanev, Tomislav, de Kraker, Marlieke E.A., Feifel, Jan, Palacios-Baena, Zaira R., Schotsman, Joost, Cantón, Rafael, Daikos, George L., Carevic, Biljana, Dragovac, Gorana, Tan, Lionel K., Raka, Lul, Hristea, Adriana, Viale, Pierluigi, Akova, Murat, Cano, Ángela, Reguera, Jose María, Bartoloni, Alessandro, Florescu, Simin-Aysel, Benea, Serban, Asensio, Ángel, Korten, Volkan, Grundmann, Hajo, Goossens, Herman, Bonten, Marc J., Gutiérrez-Gutiérrez, Belén, and Rodríguez-Baño, Jesús

Published
2024
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41. The Differentiation Potential of Apical Papilla Cells in Relation to Tenascin-C and Syndecan-1 Expression and Their Potential Role in Regeneration

Author

K. Kodonas, A. Fardi, S. Papadimitriou, and C. Gogos

Subjects
Dentistry, RK1-715
Abstract

Conclusions: Cell differentiation potential in the developing swine apex is progressively restricted to the newly formed dental pulp, whereas phenotypic expression of apical papilla cells remains undetermined unless the new microenvironment triggers cell differentiation towards the odontoblastic lineage.

Published
2024
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43. Effects of COVID-19 Infection and Vaccination on the Female Reproductive System: A Narrative Review

Author

Soheila Pourmasumi, Nicholas G. Kounis, Monavar Naderi, Robabe Hosseinisadat, Arezoo Khoradmehr, Niloofar Fagheirelahee, Sophia N. Kouni, Cesare de Gregorio, Periklis Dousdampanis, Virginia Mplani, Marina A. Michalaki, Panagiotis Plotas, Stelios Assimakopoulos, Christos Gogos, Georgios Aidonidis, Pavlos Roditis, Nikos Matsas, DimitriosVelissaris, Gianfranco Calogiuri, Ming-Yow Hung, and Ioanna Koniari

Subjects
Medicine
Abstract

Several studies and research papers have been published to elucidate and understand the mechanism of the coronavirus disease 2019 (COVID-19) pandemic and its long-term effects on the human body. COVID-19 affects a number of organs, including the female reproductive system. However, less attention has been given to the effects of COVID-19 on the female reproductive system due to their low morbidity. The results of studies investigating the relationship between COVID-19 infection and ovarian function in women of reproductive age have shown the harmless involvement of COVID-19 infection. Several studies have reported the involvement of COVID-19 infection in oocyte quality, ovarian function, and dysfunctions in the uterine endometrium and the menstrual cycle. The findings of these studies indicate that COVID-19 infection negatively affects the follicular microenvironment and dysregulate ovarian function. Although the COVID-19 pandemic and female reproductive health have been studied in humans and animals, very few studies have examined how COVID-19 affects the female reproductive system. The objective of this review is to summarize the current literature and categorize the effects of COVID-19 on the female reproductive system, including the ovaries, uterus, and hormonal profiles. The effects on oocyte maturation, oxidative stress, which causes chromosomal instability and apoptosis in ovaries, in vitro fertilization cycle, high-quality embryos, premature ovarian insufficiency, ovarian vein thrombosis, hypercoagulable state, women’s menstrual cycle, the hypothalamus-pituitary-ovary axis, and sex hormones, including estrogen, progesterone, and the anti-Müllerian hormone, are discussed in particular.

Published
2023
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44. The Role of Preoperative Chemotherapy in the Management of Synchronous Resectable Colorectal Liver Metastases: A Meta-Analysis

Author

Kostas Tepelenis, Georgios Pappas-Gogos, Panagiotis Ntellas, Konstantinos Tsimogiannis, Katerina Dadouli, Davide Mauri, and Georgios K. Glantzounis

Subjects
preoperative chemotherapy, neoadjuvant chemotherapy, synchronous colorectal liver metastases, resectable colorectal liver metastases, stage IV colorectal cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: The indications of preoperative chemotherapy, for initially resectable synchronous colorectal liver metastases, remain controversial. This meta-analysis aimed to assess the efficacy and safety of preoperative chemotherapy in such patients. Methods: Six retrospective studies were included in the meta-analysis with 1036 patients. Some 554 patients were allocated to the preoperative group, and 482 others were allocated to the surgery group. Results: Major hepatectomy was more common in the preoperative group than in the surgery group (43.1% vs. 28.8%, p < 0.001). Furthermore, the percentage of patients with more than three liver metastases was higher in the preoperative group compared to the surgery group (12.6% vs. 5.4%, p < 0.002). Preoperative chemotherapy showed no statistically significant impact on overall survival. Combined disease free/relapse survival analysis of patients with high disease burden (liver metastases > 3, maximum diameter > 5 cm, clinical risk score ≥ 3) demonstrated that there is a 12% lower risk of recurrence in favor of preoperative chemotherapy. Combined analysis showed a statistically significant (77% higher probability) of postoperative morbidity in patients who received preoperative chemotherapy (p = 0.002). Conclusions: Preoperative chemotherapy should be suggested in patients with high disease burden. The number of cycles of preoperative chemotherapy should be low (3–4) to avoid increased postoperative morbidity. However more prospective studies are needed to clarify the exact role of preoperative chemotherapy in patients with synchronous resectable colorectal liver metastases.

Published
2023
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45. Predictive Factors for Anastomotic Leakage Following Colorectal Cancer Surgery: Where Are We and Where Are We Going?

Author

Christos Tsalikidis, Athanasia Mitsala, Vasileios I. Mentonis, Konstantinos Romanidis, George Pappas-Gogos, Alexandra K. Tsaroucha, and Michail Pitiakoudis

Subjects
anastomotic leakage, colorectal cancer, colorectal surgery, risk factors, anastomotic leakage prediction, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Anastomotic leakage (AL) remains one of the most severe complications following colorectal cancer (CRC) surgery. Indeed, leaks that may occur after any type of intestinal anastomosis are commonly associated with a higher reoperation rate and an increased risk of postoperative morbidity and mortality. At first, our review aims to identify specific preoperative, intraoperative and perioperative factors that eventually lead to the development of anastomotic dehiscence based on the current literature. We will also investigate the role of several biomarkers in predicting the presence of ALs following colorectal surgery. Despite significant improvements in perioperative care, advances in surgical techniques, and a high index of suspicion of this complication, the incidence of AL remained stable during the last decades. Thus, gaining a better knowledge of the risk factors that influence the AL rates may help identify high-risk surgical patients requiring more intensive perioperative surveillance. Furthermore, prompt diagnosis of this severe complication may help improve patient survival. To date, several studies have identified predictive biomarkers of ALs, which are most commonly associated with the inflammatory response to colorectal surgery. Interestingly, early diagnosis and evaluation of the severity of this complication may offer a significant opportunity to guide clinical judgement and decision-making.

Published
2023
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47. The Hellenic Emergency Laparotomy Study (HELAS): A Prospective Multicentre Study on the Outcomes of Emergency Laparotomy in Greece

Author

Lasithiotakis, Konstantinos, Kritsotakis, Evangelos I., Kokkinakis, Stamatios, Petra, Georgia, Paterakis, Konstantinos, Karali, Garyfallia-Apostolia, Malikides, Vironas, Anastasiadis, Charalampos S., Zoras, Odysseas, Drakos, Nikolas, Kehagias, Ioannis, Kehagias, Dimitrios, Gouvas, Nikolaos, Kokkinos, Georgios, Pozotou, Ioanna, Papatheodorou, Panayiotis, Frantzeskou, Kyriakos, Schizas, Dimitrios, Syllaios, Athanasios, Palios, Ifaistion M., Nastos, Konstantinos, Perdikaris, Markos, Michalopoulos, Nikolaos V., Margaris, Ioannis, Lolis, Evangelos, Dimopoulou, Georgia, Panagiotou, Dimitrios, Nikolaou, Vasiliki, Glantzounis, Georgios K., Pappas-Gogos, George, Tepelenis, Kostas, Zacharioudakis, Georgios, Tsaramanidis, Savvas, Patsarikas, Ioannis, Stylianidis, Georgios, Giannos, Georgios, Karanikas, Michael, Kofina, Konstantinia, Markou, Markos, and Chrysos, Emmanuel

Published
2023
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48. The Glioma-Network Interface: A Review of the Relationship Between Glioma Molecular Subtype and Intratumoral Function

Author

Young, Jacob S, Morshed, Ramin A, Gogos, Andrew J, Amara, Dominic, Villanueva-Meyer, Javier E, Berger, Mitchel S, and Hervey-Jumper, Shawn L

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Brain Disorders, Cancer, Brain Cancer, Rare Diseases, Clinical Research, Neurosciences, Neurological, Brain Neoplasms, Glioma, Humans, Isocitrate Dehydrogenase, Magnetic Resonance Imaging, Retrospective Studies, High-grade glioma, Low-grade glioma, Intratumoral function, Functional mapping, Neurology & Neurosurgery, Clinical sciences, Biological psychology
Abstract

Gliomas are a major cause of morbidity. Direct cortical stimulation mapping offers the ability to identify functional areas within the broader neural network both cortically and subcortically. Since the World Health Organization (WHO) 2016 classification categorized gliomas into molecular subgroups with varied molecular signatures and clinical behavior, it is possible that gliomas may demonstrate rates of functional network integration. We therefore retrospectively reviewed a data registry of 181 patients with dominant hemisphere frontal, parietal, insular, or temporal gliomas. Our goal was to test the hypothesis that WHO glioma histopathology and molecular subtype influences functional language or motor sites identified within the tumor. Intratumoral function as determined by direct cortical and subcortical stimulation mapping was identified at the highest rate in isocitrate dehydrogenase mutant astrocytomas and oligodendrogliomas. Finally, we reviewed the emerging literature exploring the interface between functional neural networks and gliomas. These data shed light on glioma molecular and histological characteristics most commonly associated within intratumoral function.

Published
2020

49. Impact of Prior COVID-19 Immunization and/or Prior Infection on Immune Responses and Clinical Outcomes

Author

Achilleas Livieratos, Charalambos Gogos, and Karolina Akinosoglou

Subjects
SARS-CoV-2 infection, immune responses, humoral immunity, transmission, vaccination, cellular immunity, Microbiology, QR1-502
Abstract

Cellular and humoral immunity exhibit dynamic adaptation to the mutating SARS-CoV-2 virus. It is noteworthy that immune responses differ significantly, influenced by whether a patient has received vaccination or whether there is co-occurrence of naturally acquired and vaccine-induced immunity, known as hybrid immunity. The different immune reactions, conditional on vaccination status and the viral variant involved, bear implications for inflammatory responses, patient outcomes, pathogen transmission rates, and lingering post-COVID conditions. Considering these developments, we have performed a review of recently published literature, aiming to disentangle the intricate relationships among immunological profiles, transmission, the long-term health effects post-COVID infection poses, and the resultant clinical manifestations. This investigation is directed toward understanding the variability in the longevity and potency of cellular and humoral immune responses elicited by immunization and hybrid infection.

Published
2024
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50. Amphotericin B in the Era of New Antifungals: Where Will It Stand?

Author

Karolina Akinosoglou, Emmanouil Angelos Rigopoulos, Despoina Papageorgiou, Georgios Schinas, Eleni Polyzou, Effrosyni Dimopoulou, Charalambos Gogos, and George Dimopoulos

Subjects
amphotericin B, mycoses, fungal infections, drug resistance, fungal, liposomes, Biology (General), QH301-705.5
Abstract

Amphotericin B (AmB) has long stood as a cornerstone in the treatment of invasive fungal infections (IFIs), especially among immunocompromised patients. However, the landscape of antifungal therapy is evolving. New antifungal agents, boasting novel mechanisms of action and better safety profiles, are entering the scene, presenting alternatives to AmB’s traditional dominance. This shift, prompted by an increase in the incidence of IFIs, the growing demographic of immunocompromised individuals, and changing patterns of fungal resistance, underscores the continuous need for effective treatments. Despite these challenges, AmB’s broad efficacy and low resistance rates maintain its essential status in antifungal therapy. Innovations in AmB formulations, such as lipid complexes and liposomal delivery systems, have significantly mitigated its notorious nephrotoxicity and infusion-related reactions, thereby enhancing its clinical utility. Moreover, AmB’s efficacy in treating severe and rare fungal infections and its pivotal role as prophylaxis in high-risk settings highlight its value and ongoing relevance. This review examines AmB’s standing amidst the ever-changing antifungal landscape, focusing on its enduring significance in current clinical practice and exploring its potential future therapeutic adaptations.

Published
2024
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