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3. Correction to: A Computational Platform Integrating a Mechanistic Model of Crohn’s Disease for Predicting Temporal Progression of Mucosal Damage and Healing

Author

Venkatapurapu, Sai Phanindra, Iwakiri, Ryuichi, Udagawa, Eri, Patidar, Nikhil, Qi, Zhen, Takayama, Ryoko, Kumar, Kei, Sato, Yuki, Behar, Marcelo, Offner, Patrick, Dwivedi, Gaurav, Miyasaka, Haruna, Suzuki, Ryohsuke Ken, Hamada, Anna Lissa, D’Alessandro, Paul M., and Fernandez, Jovelle

Published
2023
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5. Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn’s Disease

Author

Andoh, Akira, Ashida, Toshifumi, Endo, Katsuya, Endo, Yutaka, Esaki, Motohiro, Fujita, Hiroshi, Fujiya, Mikihiro, Haruma, Ken, Hibi, Toshifumi, Hiraoka, Sakiko, Hirata, Ichiro, Hisamatsu, Tadakazu, Honda, Yutaka, Iijima, Hideki, Iizuka, Bunei, Ikeya, Kentaro, Inoue, Takuya, Inoue, Syuji, Ishida, Tetsuya, Ishiguro, Yo, Ishihara, Shyunji, Ito, Hiroaki, Iwakiri, Ryuichi, Kagaya, Takashi, Kanai, Takanori, Kashida, Hiroshi, Kato, Shingo, Kato, Jun, Katsurada, Takehiko, Kinjyo, Fukunori, Kobayashi, Kiyonori, Kodama, Mayumi, Kunisaki, Reiko, Kurahara, Koichi, Kurokami, Takafumi, Kyouwon, Lee, Matsuda, Koichiro, Matsueda, Kazuhiro, Matsui, Toshiyuki, Matsumoto, Takayuki, Mitsuyama, Keiichi, Mizokami, Yuji, Motoya, Satoshi, Naito, Yuji, Nakagawa, Tomoo, Nakamura, Shiro, Nakase, Hiroshi, Nojima, Masanori, Nomura, Masafumi, Ogawa, Atsuhiro, Okazaki, Kazuichi, Otsuka, Kazuaki, Sakuraba, Hirotake, Saruta, Masayuki, Sasaki, Makoto, Shirai, Takayuki, Suga, Tomoaki, Sugimura, Kazuhito, Sugiyama, Toshiro, Suzuki, Yasuo, Takeshima, Fuminao, Tamaki, Hiroyuki, Tanaka, Shinji, Tanida, Satoshi, Tominaga, Keiichi, Tomizawa, Taku, Watababe, Kenji, Watanabe, Mamoru, Watanabe, Kenji, Yamamoto, Syojiro, Yamashita, Masaki, Yoshida, Atsushi, Yoshimura, Naoki, and Nagahori, Masakazu

Published
2018
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6. Current status of esophageal endoscopy including the evaluation of smoking and alcohol consumption in Japan: an analysis based on the Japan endoscopy database

Author

Katada, Chikatoshi, Horimatsu, Takahiro, Muto, Manabu, Tanaka, Kiyohito, Matsuda, Koji, Fujishiro, Mitsuhiro, Saito, Yutaka, Ohtsuka, Kazuo, Oda, Ichiro, Kato, Masayuki, Kida, Mitsuhiro, Kobayashi, Kiyonori, Hoteya, Shu, Kodashima, Shinya, Matsuda, Takahisa, Yamamoto, Hironori, Ryozawa, Shomei, Iwakiri, Ryuichi, Kutsumi, Hiromu, Miyata, Hiroaki, Kato, Mototsugu, Haruma, Ken, Fujimoto, Kazuma, Uemura, Naomi, Kaminishi, Michio, and Tajiri, Hisao

Published
2019
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11. Computational Simulation Model to Predict Behavior Changes in Inflammatory Bowel Disease Patients during the COVID-19 Pandemic: Analysis of Two Regional Japanese Populations

Author

Suzuki, Gen, primary, Iwakiri, Ryuichi, additional, Udagawa, Eri, additional, Ma, Sindy, additional, Takayama, Ryoko, additional, Nishiura, Hiroshi, additional, Nakamura, Koshi, additional, Burns, Samuel P., additional, D’Alessandro, Paul Michael, additional, and Fernandez, Jovelle, additional

Published
2023
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13. Correction to: A Computational Platform Integrating a Mechanistic Model of Crohn’s Disease for Predicting Temporal Progression of Mucosal Damage and Healing

Author

Venkatapurapu, Sai Phanindra, primary, Iwakiri, Ryuichi, additional, Udagawa, Eri, additional, Patidar, Nikhil, additional, Qi, Zhen, additional, Takayama, Ryoko, additional, Kumar, Kei, additional, Sato, Yuki, additional, Behar, Marcelo, additional, Offner, Patrick, additional, Dwivedi, Gaurav, additional, Miyasaka, Haruna, additional, Suzuki, Ryohsuke Ken, additional, Hamada, Anna Lissa, additional, D’Alessandro, Paul M., additional, and Fernandez, Jovelle, additional

Published
2022
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14. Helicobacter pylori infection status had no influence on upper gastrointestinal symptoms: a cross-sectional analysis of 3,005 Japanese subjects without upper gastrointestinal lesions undergoing medical health checkups

Author

Yoshioka, Tomomi, Takeshita, Eri, Sakata, Yasuhisa, Hara, Megumi, Akutagawa, Kayo, Sakata, Natsuko, Endo, Hiroyoshi, Ohyama, Takashi, Matsunaga, Keiji, Tanaka, Yuichiro, Shirai, Shinpei, Ito, Yoichiro, Tsuruoka, Nanae, Iwakiri, Ryuichi, Kusano, Motoyasu, and Fujimoto, Kazuma

Published
2017
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17. First progress report on the Japan Endoscopy Database project

Author

Kodashima, Shinya, Tanaka, Kiyohito, Matsuda, Koji, Fujishiro, Mitsuhiro, Saito, Yutaka, Ohtsuka, Kazuo, Oda, Ichiro, Katada, Chikatoshi, Kato, Masayuki, Kida, Mitsuhiro, Kobayashi, Kiyonori, Hoteya, Shu, Horimatsu, Takahiro, Matsuda, Takahisa, Muto, Manabu, Yamamoto, Hironori, Ryozawa, Shomei, Iwakiri, Ryuichi, Kutsumi, Hiromu, Miyata, Hiroaki, Kato, Mototsugu, Haruma, Ken, Fujimoto, Kazuma, Uemura, Naomi, Kaminishi, Michio, and Tajiri, Hisao

Published
2018
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18. Design paper: Japan Endoscopy Database (JED): A prospective, large database project related to gastroenterological endoscopy in Japan

Author

Matsuda, Koji, Tanaka, Kiyohito, Fujishiro, Mitsuhiro, Saito, Yutaka, Ohtsuka, Kazuo, Oda, Ichiro, Katada, Chikatoshi, Kato, Masayuki, Kida, Mitsuhiro, Kobayashi, Kiyonori, Hoteya, Shu, Horimatsu, Takahiro, Kodashima, Shinya, Matsuda, Takahisa, Muto, Manabu, Yamamoto, Hironori, Ryozawa, Shomei, Iwakiri, Ryuichi, Kutsumi, Hiromu, Miyata, Hiroaki, Kato, Mototsugu, Haruma, Ken, Fujimoto, Kazuma, Uemura, Naomi, Kaminishi, Michio, and Tajiri, Hisao

Published
2018
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19. Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

Author

Iwakiri, Katsuhiko, Kinoshita, Yoshikazu, Habu, Yasuki, Oshima, Tadayuki, Manabe, Noriaki, Fujiwara, Yasuhiro, Nagahara, Akihito, Kawamura, Osamu, Iwakiri, Ryuichi, Ozawa, Soji, Ashida, Kiyoshi, Ohara, Shuichi, Kashiwagi, Hideyuki, Adachi, Kyoichi, Higuchi, Kazuhide, Miwa, Hiroto, Fujimoto, Kazuma, Kusano, Motoyasu, Hoshihara, Yoshio, Kawano, Tatsuyuki, Haruma, Ken, Hongo, Michio, Sugano, Kentaro, Watanabe, Mamoru, and Shimosegawa, Tooru

Published
2016
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20. Efficacy of biologic therapies for biologic-naïve Japanese patients with moderately to severely active ulcerative colitis: a network meta-analysis

Author

Hibi, Toshifumi, Kamae, Isao, Pinton, Philippe, Ursos, Lyann, Iwakiri, Ryuichi, Hather, Greg, and Patel, Haridarshan

Subjects
medicine.medical_specialty, efficacy, lcsh:Medicine, Placebo, Vedolizumab, law.invention, Randomized controlled trial, law, Internal medicine, medicine, Adalimumab, biologics, lcsh:RC799-869, network meta-analysis, colitis, ulcerative, business.industry, lcsh:R, Gastroenterology, Odds ratio, Inflammatory Bowel Diseases, medicine.disease, Ulcerative colitis, Infliximab, Golimumab, Original Article, lcsh:Diseases of the digestive system. Gastroenterology, business, medicine.drug
Abstract

Background/Aims: Several biologic therapies are approved in Japan to treat moderately to severely active ulcerative colitis (UC), but there are no published comparative efficacy studies in a Japanese population. We compared the efficacy of biologics approved in Japan (adalimumab, infliximab, golimumab, and vedolizumab) for treating biologic-naive patients with UC at their approved doses. Methods: A targeted literature review identified 4 randomized controlled trials of biologics for UC in biologic-naive Japanese patients. For each study, efficacy outcome data from induction (weeks 6-12) and maintenance (weeks 30-60) treatment were extracted for analysis. Treatment effects on clinical response, clinical remission, and mucosal healing relative to the average placebo results across all trials were estimated using network meta-analyses followed by transformation into probabilities and odds ratios (OR). Results: At the end of induction, the likelihood of clinical response and clinical remission was highest with infliximab (OR: 2.12 and 2.35, respectively) and vedolizumab (OR: 2.10 and 2.32, respectively); the likelihood of mucosal healing was highest with infliximab (OR: 2.24) and adalimumab (OR: 1.86). During maintenance, the likelihood of clinical response and clinical remission was highest with vedolizumab (OR: 6.44 and 4.68, respectively) and golimumab (OR: 5.13 and 3.84, respectively); the likelihood of mucosal healing was significantly higher than placebo with all biologics. Conclu sions: All active treatments were efficacious compared with placebo. Infliximab and vedolizumab had the highest odds for induction of clinical response, remission, and mucosal healing. Golimumab and vedolizumab had numerically higher odds of achieving efficacy outcomes in the maintenance phase. (Intest Res 2021;19:53-61)

Published
2021

21. Significance of measurement of serum trough level and anti‐drug antibody of adalimumab as personalised pharmacokinetics in patients with Crohnʼs disease: a subanalysis of the DIAMOND trial

Author

Nakase, H., Motoya, S., Matsumoto, T., Watanabe, K., Hisamatsu, T., Yoshimura, N., Ishida, T., Kato, S., Nakagawa, T., Esaki, M., Nagahori, M., Matsui, T., Naito, Y., Kanai, T., Suzuki, Y., Nojima, M., Watanabe, M., Hibi, T., Andoh, Akira, Ashida, Toshifumi, Endo, Katsuya, Endo, Yutaka, Esaki, Motohiro, Fujita, Hiroshi, Fujiya, Mikihiro, Haruma, Ken, Hibi, Toshifumi, Hiraoka, Sakiko, Hirata, Ichiro, Hisamatsu, Tadakazu, Honda, Yutaka, Iijima, Hideki, Iizuka, Bunei, Ikeya, Kentaro, Inoue, Takuya, Inoue, Shuji, Ishida, Tetsuya, Ishiguro, Yo, Ishihara, Shunji, Ito, Hiroaki, Iwakiri, Ryuichi, Kagaya, Takashi, Kanai, Takanori, Kashida, Hiroshi, Kato, Shingo, Kato, Jun, Katsurada, Takehiko, Kinjyo, Fukunori, Kobayashi, Kiyonori, Kodama, Mayumi, Kunisaki, Reiko, Kurahara, Koichi, Kurokami, Takafumi, Kyouwon, Lee, Matsuda, Koichiro, Matsueda, Kazuhiro, Matsui, Toshiyuki, Matsumoto, Takayuki, Mitsuyama, Keiichi, Mizokami, Yuji, Motoya, Satoshi, Naito, Yuji, Nakagawa, Tomoo, Nakamura, Shiro, Nakase, Hiroshi, Nojima, Masanori, Nomura, Masafumi, Ogawa, Atsuhiro, Okazaki, Kazuichi, Otsuka, Kazuaki, Sakuraba, Hirotake, Saruta, Masayuki, Sasaki, Makoto, Shirai, Takayuki, Suga, Tomoaki, Sugimura, Kazuhito, Sugiyama, Toshiro, Suzuki, Yasuo, Takeshima, Fuminao, Tamaki, Hiroyuki, Tanaka, Shinji, Tanida, Satoshi, Tominaga, Keiichi, Tomizawa, Taku, Watanabe, Kenji, Watanabe, Mamoru, Yamamoto, Shojiro, Yamashita, Masaki, Yoshida, Atsushi, and Yoshimura, Naoki

Published
2017
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22. Treatment Patterns in Newly Diagnosed Patients with Crohn's Disease Who Received Biologics Following Diagnosis: A Nationwide, Retrospective, Longitudinal, Observational Study Using a Medical Claims Database in Japan.

Author

Hirai, Fumihito, Uda, Akihito, Ota, Mihoko, Takemura, Yukiko, Tanaka, Keisuke, and Iwakiri, Ryuichi

Subjects
CROHN'S disease, MEDICAL databases, BIOLOGICALS, DIAGNOSIS, DIET therapy
Abstract

Introduction: Crohn's disease (CD) is a chronic inflammatory condition affecting any part of the gastrointestinal tract. Current therapies involve pharmacological efforts to dampen inflammation. Biologics are recommended for patients with steroid-dependent or steroid-refractory disease; however, little is known about current biologic use in real-world settings in Japan. Methods: This observational, longitudinal, cohort study utilized the Japan Medical Data Center (JMDC) database to analyze claims data of patients who were prescribed ≥1 biologic (adalimumab, infliximab, or ustekinumab) following a new CD diagnosis made between January 2009 and January 2019. We primarily assessed the type of first-line treatment prescribed within 6 months of a patient's first CD diagnosis. Results: Of the 1,346 eligible patients, the most common prescriptions were 5-aminosalicylic acid (5-ASA) monotherapy (26.8%), 5-ASA plus biologic combination (26.3%), and biologic monotherapy (12.9%). First-line biologics were prescribed within 6 months of initial CD diagnosis in 61.1% of patients, either alone or in combination with other therapies. As an individual first-line treatment, the proportion of patients receiving prescriptions of infliximab was high (66.3%) and steroids, low (1.3%). Patients who had a procedure to inspect the small intestine, such as endoscopy (n = 508), were mostly treated with a nonbiologic therapy (74.8%), whereas those who had not (n = 838), mostly received biologics (alone or in combination, 82.8%) as a first-line treatment. Conclusions: In this study, we discovered the typical treatment pattern of patients with CD who received biologics and are registered in the JMDC database in Japan. Biologics were commonly used in the early phase of CD treatment. Treatment with traditional approaches such as steroids and nutritional therapy with evaluation for small intestine lesions, before turning to the use of biologics, may be prudent for achieving optimal outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Risk factors for low response to proton-pump inhibitor treatment in reflux esophagitis and non-erosive reflux disease evaluated by the frequency scale for the symptoms of gastroesophageal reflux disease

Author

Akutagawa, Kayo, Iwakiri, Ryuichi, Hara, Megumi, Fujimoto, Kazuma, Fujiwara, Yasuhiro, Inamori, Masahiko, Tanaka, Junji, Shimatani, Tomohiko, Akiyama, Junichi, Ando, Takashi, Manabe, Noriaki, Kinjo, Fukunori, Deguchi, Ryuzo, and Kusano, Motoyasu

Published
2015
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31. Current status of diagnostic and therapeutic colonoscopy in Japan: The Japan Endoscopic Database Project

Author

Saito, Yutaka, primary, Kodashima, Shinya, additional, Matsuda, Takahisa, additional, Matsuda, Koji, additional, Fujishiro, Mitsuhiro, additional, Tanaka, Kiyohito, additional, Kobayashi, Kiyonori, additional, Katada, Chikatoshi, additional, Horimatsu, Takahiro, additional, Muto, Manabu, additional, Ohtsuka, Kazuo, additional, Oda, Ichiro, additional, Kato, Masayuki, additional, Kida, Mitsuhiro, additional, Hoteya, Shu, additional, Yamamoto, Hironori, additional, Ryozawa, Shomei, additional, Iwakiri, Ryuichi, additional, Kutsumi, Hiromu, additional, Kato, Mototsugu, additional, Haruma, Ken, additional, Fujimoto, Kazuma, additional, Iishi, Hiroyasu, additional, Ogata, Haruhiko, additional, Uemura, Naomi, additional, Kaminishi, Michio, additional, Tajiri, Hisao, additional, and Inoue, Haruhiro, additional

Published
2021
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32. Decline incidence in upper gastrointestinal bleeding in several recent years: data of the Japan claims database of 13 million accumulated patients

Author

Fujimoto, Shun, primary, Tsuruoka, Nanae, additional, Esaki, Motohiro, additional, Takamori, Ayako, additional, Sakata, Yasuhisa, additional, Shimoda, Ryo, additional, Akutagawa, Takashi, additional, Node, Koichi, additional, Anzai, Keizo, additional, Sugisaki, Nobuyuki, additional, Iwakiri, Ryuichi, additional, Takagi, Kuniaki, additional, Yamanouchi, Kohei, additional, and Fujimoto, Kazuma, additional

Published
2021
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33. Long-Term Follow-Up of Targeted Biopsy Yield (LOFTY Study) in Ulcerative Colitis Surveillance Colonoscopy

Author

Hata, Keisuke, primary, Ishihara, Soichiro, additional, Ajioka, Yoichi, additional, Mitsuyama, Keiichi, additional, Watanabe, Kenji, additional, Hanai, Hiroyuki, additional, Kunisaki, Reiko, additional, Nakase, Hiroshi, additional, Matsuda, Keiji, additional, Iwakiri, Ryuichi, additional, Hida, Nobuyuki, additional, Tanaka, Shinji, additional, Takeuchi, Yoshiaki, additional, Shinozaki, Masaru, additional, Ogata, Noriyuki, additional, Moriichi, Kentaro, additional, Hirai, Fumihito, additional, Sugihara, Kenichi, additional, Hisamatsu, Tadakazu, additional, Suzuki, Yasuo, additional, Watanabe, Mamoru, additional, and Hibi, Toshifumi, additional

Published
2020
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36. Risk Factors for Helicobacter pylori Infection and Endoscopic Reflux Esophagitis in Healthy Young Japanese Volunteers

Author

Tanaka, Yuichiro, Sakata, Yasuhisa, Hara, Megumi, Kawakubo, Hiroharu, Tsuruoka, Nanae, Yamamoto, Koji, Itoh, Yoichiro, Hidaka, Hidenori, Shimoda, Ryo, Iwakiri, Ryuichi, and Fujimoto, Kazuma

Subjects
Adult, Male, Volunteers, nodular gastritis, F scale, Helicobacter pylori, gastroesophageal reflux, dyspepsia, Antibodies, Bacterial, Endoscopy, Gastrointestinal, Body Mass Index, Helicobacter Infections, Young Adult, Sex Factors, Japan, Risk Factors, Duodenal Ulcer, Immunoglobulin G, Prevalence, Humans, Original Article, endoscopy
Abstract

Objective The aim of this study was to determine the prevalence and risk factors of reflux esophagitis and Helicobacter pylori (H.pylori) infection and their interrelationship in healthy young Japanese volunteers. Methods Between 2010 and 2016, 550 fifth-year medical students at Saga Medical School, aged 22 to 30 years, underwent upper gastrointestinal endoscopy and completed a questionnaire (frequency scale for symptoms of gastroesophageal reflux disease). H. pylori infection was determined by detecting urinary immunoglobulin G antibodies. Results H. pylori antibodies were detected in 45 of the 550 subjects (8.2%). Endoscopic reflux esophagitis was detected in 38 out of 550 (6.9%): grade A in 37 subjects (97.3%) and grade B in 1. Most subjects with reflux esophagitis were H. pylori-negative (35/37). Nodular gastritis was observed in 33.3% (15/45) of H. pylori-positive subjects. The risk factors for H. pylori infection were drinking well water in childhood, nodular gastritis, and duodenal ulcer scars. The risk factors for endoscopic reflux esophagitis were male gender and obesity (body mass index ≥25). Conclusion This study describes the risk factors for H. pylori infection and reflux esophagitis in healthy young Japanese subjects. The prevalence of reflux esophagitis was relatively high, and the infection rate of H. pylori was low compared with the aged Japanese population.

Published
2017

37. Current status of diagnostic and therapeutic colonoscopy in Japan: The Japan Endoscopic Database Project.

Author

Saito, Yutaka, Kodashima, Shinya, Matsuda, Takahisa, Matsuda, Koji, Fujishiro, Mitsuhiro, Tanaka, Kiyohito, Kobayashi, Kiyonori, Katada, Chikatoshi, Horimatsu, Takahiro, Muto, Manabu, Ohtsuka, Kazuo, Oda, Ichiro, Kato, Masayuki, Kida, Mitsuhiro, Hoteya, Shu, Yamamoto, Hironori, Ryozawa, Shomei, Iwakiri, Ryuichi, Kutsumi, Hiromu, and Kato, Mototsugu

Subjects
COLONOSCOPY, ENDOSCOPIC surgery, MEDICAL screening, DATABASE management software, RATE setting
Abstract

Objectives: The Japan Endoscopy Database Project was initiated to develop the world's largest endoscopy data repository. This study describes the first phase of the colonoscopy project in Japan. Methods: Data were aggregated offline by integrating information from the endoscopy database software from January 2015 through March 2017. The study population included all patients who underwent colonoscopy at eight centers. Results: A total of 31,395 patients who underwent 38,497 colonoscopy procedures were registered. The majority of procedures were performed for screening (n = 14,156), followed by fecal immunochemical test positivity (n = 3960), abdominal symptoms (n = 3864), post‐colorectal surgery surveillance (n = 3431), post‐endoscopic treatment surveillance (n = 3757), thorough pre‐treatment examination (n = 2822), and therapeutic purposes (n = 6507). In the screening group, advanced cancers, early cancers, and adenomas were diagnosed endoscopically in 2.1%, 1.3%, and 28.7% of cases, respectively, while in the fecal immunochemical test‐positive group, they were diagnosed in 2.5%, 1.9%, and 41.6% of cases, respectively. The incidence of complications was 0.177% and 0.152% in the screening and fecal immunochemical test‐positive groups, respectively. The therapeutic procedures included 1446 cold forceps polypectomy procedures, 4770 cold snare polypectomy procedures, 368 hot biopsies, 2998 hot snare polypectomy procedures, 9775 endoscopic or piecemeal endoscopic mucosal resections, and 1660 endoscopic submucosal dissections. A total of 173 procedure‐related complications (0.82%) occurred in 21,017 therapeutic procedures performed in 15,744 patients. Conclusions: The first phase of the Japan Endoscopy Database Project established the proportions of the diagnostic and therapeutic colonoscopy procedures, and complication rates in real‐world settings. [ABSTRACT FROM AUTHOR]

Published
2022
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39. Multicenter database registry for endoscopic retrograde cholangiopancreatography: Japan Endoscopic Database Project

Author

Kato, Masayuki, primary, Tanaka, Kiyohito, additional, Kida, Mitsuhiro, additional, Ryozawa, Shomei, additional, Matsuda, Koji, additional, Fujishiro, Mitsuhiro, additional, Saito, Yutaka, additional, Ohtsuka, Kazuo, additional, Oda, Ichiro, additional, Katada, Chikatoshi, additional, Kobayashi, Kiyonori, additional, Hoteya, Shu, additional, Horimatsu, Takahiro, additional, Kodashima, Shinya, additional, Matsuda, Takahisa, additional, Muto, Manabu, additional, Yamamoto, Hironori, additional, Iwakiri, Ryuichi, additional, Kutsumi, Hiromu, additional, Miyata, Hiroaki, additional, Kato, Mototsugu, additional, Haruma, Ken, additional, Fujimoto, Kazuma, additional, Uemura, Naomi, additional, Kaminishi, Michio, additional, and Tajiri, Hisao, additional

Published
2019
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41. Guidelines for standardizing cleansing and disinfection of gastrointestinal endoscopes

Author

Iwakiri, Ryuichi, primary, Tanaka, Kiyohito, additional, Gotoda, Takuji, additional, Oka, Shiro, additional, Ohtsuka, Takao, additional, Sakata, Yasuhisa, additional, Chiba, Toshimi, additional, Higuchi, Kazuhide, additional, Masuyama, Hironori, additional, Nozaki, Ryoichi, additional, Matsuda, Koji, additional, Shimono, Nobuyuki, additional, Fujimoto, Kazuma, additional, and Tajiri, Hisao, additional

Published
2019
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43. Questionnaire-Based Survey on Management of Ulcerative Colitis-Associated Cancer in East Asian Countries

Author

Yamaguchi, Satoru, primary, Sasaki, Kinro, additional, Kato, Hiroyuki, additional, Fukudo, Shin, additional, Iwakiri, Ryuichi, additional, Kamiya, Takeshi, additional, Motoya, Satoshi, additional, Murakami, Kazunari, additional, Nagahara, Akihito, additional, Suzuki, Hidekazu, additional, Watanabe, Toshio, additional, Takahashi, Shin’ichi, additional, Chan, Francis K.L., additional, Hahm, Ki-Baik, additional, Kachintorn, Udom, additional, Ming, Fock Kwong, additional, Rani, Abdul Aziz, additional, Sollano, Jose D., additional, and Zhu, Qi, additional

Published
2018
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44. Shorter Relapse-Free Period after Leukocyte Removal Therapy in Younger than Older Patients with Ulcerative Colitis

Author

Yamasaki, Satoko, primary, Sakata, Yasuhisa, additional, Yoshida, Hisako, additional, Shirai, Sinpei, additional, Tanaka, Yuichiro, additional, Nakano, Ryo, additional, Yukimoto, Takahiro, additional, Tsuruoka, Nanae, additional, Shimoda, Ryo, additional, Fukuda, Makoto, additional, Miyazono, Motoaki, additional, Ikeda, Yuji, additional, Iwakiri, Ryuichi, additional, Anzai, Keizo, additional, and Fujimoto, Kazuma, additional

Published
2018
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45. Current status of esophageal endoscopy including the evaluation of smoking and alcohol consumption in Japan: an analysis based on the Japan endoscopy database

Author

Katada, Chikatoshi, primary, Horimatsu, Takahiro, additional, Muto, Manabu, additional, Tanaka, Kiyohito, additional, Matsuda, Koji, additional, Fujishiro, Mitsuhiro, additional, Saito, Yutaka, additional, Ohtsuka, Kazuo, additional, Oda, Ichiro, additional, Kato, Masayuki, additional, Kida, Mitsuhiro, additional, Kobayashi, Kiyonori, additional, Hoteya, Shu, additional, Kodashima, Shinya, additional, Matsuda, Takahisa, additional, Yamamoto, Hironori, additional, Ryozawa, Shomei, additional, Iwakiri, Ryuichi, additional, Kutsumi, Hiromu, additional, Miyata, Hiroaki, additional, Kato, Mototsugu, additional, Haruma, Ken, additional, Fujimoto, Kazuma, additional, Uemura, Naomi, additional, Kaminishi, Michio, additional, and Tajiri, Hisao, additional

Published
2018
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46. Multicenter database registry for endoscopic retrograde cholangiopancreatography: Japan Endoscopic Database Project.

Author

Kato, Masayuki, Tanaka, Kiyohito, Kida, Mitsuhiro, Ryozawa, Shomei, Matsuda, Koji, Fujishiro, Mitsuhiro, Saito, Yutaka, Ohtsuka, Kazuo, Oda, Ichiro, Katada, Chikatoshi, Kobayashi, Kiyonori, Hoteya, Shu, Horimatsu, Takahiro, Kodashima, Shinya, Matsuda, Takahisa, Muto, Manabu, Yamamoto, Hironori, Iwakiri, Ryuichi, Kutsumi, Hiromu, and Miyata, Hiroaki

Subjects
ENDOSCOPIC retrograde cholangiopancreatography, CLINICAL trial registries, DATABASES, DATA entry, BILE ducts, LEVEL of difficulty
Abstract

Background and Aim: Few studies have reported on a national, population‐based endoscopic retrograde cholangiopancreatography (ERCP) database. Hence, in 2015, we established a multicenter ERCP database registry, the Japan Endoscopic Database (JED) Project in preparation for a nationwide endoscopic database. The objective the present study was to evaluate this registry before the establishment of a nationwide endoscopic database. Methods: From 1 January 2015 to 31 March 2017, we collected and analyzed the ERCP data of all patients who underwent ERCP in four participating centers in the JED Project based on the JED protocol. Results: Four centers carried out 4104 ERCP on 2173 patients. Data entry of ERCP information (age, 100%; gender, 100%; American Society of Anesthesiologists Physical Status Classification System, 74.5%; scope, 92.7%; time to ERCP, 100%; antithrombotic drug information, 55.0%; primary selective common bile duct [CBD] cannulation methods, 73.0%; number of attempts at primary selective CBD cannulation, 67.6%; overall selective CBD cannulation methods, 68.9%; ERCP procedure time, 66.3%; fluoroscopy time, 65.1%; adverse events, 74.9%; serum amylase levels 1 day post‐ERCP, 36.5%) was accurately extracted from the four centers. Success rate of CBD cannulation by level of ERCP difficulty was 98.5%, 99.0%, and 96.4% in grades 1, 2, and 3, respectively. Complication rate by overall selective CBD cannulation method was 5.6%, 7.6%, and 10.5% in the contrast‐assisted technique, guidewire‐assisted technique, and cross‐over method, respectively. Conclusion: Data from this evaluation of the JED Project, a multicenter ERCP database registry, suggest the feasibility of establishing a nationwide ERCP database and its challenges. [ABSTRACT FROM AUTHOR]

Published
2020
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47. Management of Gastroesophageal Reflux Disease in Asian Countries: Results of a Questionnaire Survey.

Author

Hojo, Mariko, Nagahara, Akihito, Hahm, Ki-Baik, Iwakiri, Ryuichi, Watanabe, Toshio, Rani, Abdul Aziz, Zhu, Qi, Chan, Francis K.L., Sollano, Jose D., Kamiya, Takeshi, Yamaguchi, Satoru, Motoya, Satoshi, Fock, Kwong Ming, Fukudo, Shin, Kachintorn, Udom, Suzuki, Hidekazu, and Murakami, Kazunari

Subjects
BARRETT'S esophagus, SURVEYS, PROTON pump inhibitors, HEARTBURN, GASTROESOPHAGEAL reflux
Abstract

Introduction: The Asia-Pacific consensus on the management of gastroesophageal reflux disease (GERD) and the GERD treatment guidelines of 2015 drawn up by the Japanese Society of Gastroenterology were proposed, and GERD management in Asian regions was assumed to be performed based on these consensuses. In this environment, the current status of GERD management in clinical practice among Asian regions is less well-known. Objective: This questionnaire-based consensus survey was performed to clarify the current status of management of GERD in clinical practice in Asian regions. Methods: A questionnaire related to management of GERD was distributed to members of the International Gastroenterology Consensus Symposium Study Group. We analyzed the questionnaire responses and compared the results among groups. Results: The frequencies of erosive GERD (ERD), non-ERD, uninvestigated GERD, and Barrett's esophagus varied significantly among Asian countries. The most important factor in diagnosing GERD was the presence of symptoms in all countries. A proton pump inhibitor was the most commonly prescribed drug to treat GERD in all countries. Endoscopic surveillance for GERD was performed regularly. Conclusion: This questionnaire survey revealed the current status of management of GERD in clinical practice in various Asian countries. [ABSTRACT FROM AUTHOR]

Published
2020
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48. The Effects of Direct Oral Anticoagulants, Warfarin, Aspirin and Thienopyridine on the Performance of Immunochemical, Faecal, Occult Blood Tests

Author

Niikura, Ryota, primary, Yamada, Atsuo, additional, Fujishiro, Mitsuhiro, additional, Tanaka, Kiyohito, additional, Matsuda, Koji, additional, Saito, Yutaka, additional, Ohtsuka, Kazuo, additional, Oda, Ichiro, additional, Katada, Chikatoshi, additional, Kato, Masayuki, additional, Kida, Mitsuhiro, additional, Kobayashi, Kiyonori, additional, Hoteya, Shu, additional, Horimatsu, Takahiro, additional, Kodashima, Shinya, additional, Matsuda, Takahisa, additional, Muto, Manabu, additional, Yamamoto, Hironori, additional, Ryozawa, Shomei, additional, Iwakiri, Ryuichi, additional, Kutsumi, Hiromu, additional, Miyata, Hiroaki, additional, Kato, Mototsugu, additional, Haruma, Ken, additional, Fujimoto, Kazuma, additional, Uemura, Naomi, additional, Kaminishi, Michio, additional, Shinozaki, Tomohiro, additional, Tajiri, Hisao, additional, and Koike, Kazuhiko, additional

Published
2018
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49. Correction to: A case–control study of the risk of upper gastrointestinal mucosal injuries in patients prescribed concurrent NSAIDs and antithrombotic drugs based on data from the Japanese national claims database of 13 million accumulated patients

Author

Sugisaki, Nobuyuki, primary, Iwakiri, Ryuichi, additional, Tsuruoka, Nanae, additional, Sakata, Yasuhisa, additional, Shimoda, Ryo, additional, Fujimoto, Shun, additional, Eguchi, Yuichiro, additional, and Fujimoto, Kazuma, additional

Published
2018
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