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Your search keyword '"José Maldonado-Lozano"' showing total 4 results
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4 results on '"José Maldonado-Lozano"'

1. Moderating Effect of Changes in Perceived Social Support during Pregnancy on the Emotional Health of Mothers and Fathers and on Baby’s Anthropometric Parameters at Birth

Author

María José Castelar-Ríos, Macarena De los Santos-Roig, Humbelina Robles-Ortega, Miguel Ángel Díaz-López, José Maldonado-Lozano, and Mercedes Bellido-González

Subjects
depression, stress, perceived social support, protective factors, birth weight, cephalisation index, Pediatrics, RJ1-570
Abstract

(1) Background: this study is based on a model of how changes in protective factors may affect the emotional health of mothers and fathers and thus influence the development of the baby. Our research goal is to determine whether variations in perceived social support moderate levels of stress and depression during pregnancy and/or the effect of parents’ emotional health on the baby’s anthropometric parameters. (2) Methods: to achieve these aims, a longitudinal study was made of 132 couples and babies, who were evaluated at weeks 12 and 32 of gestation and at birth. Separate analyses were performed for the mothers and fathers, focused on the role of social support in moderating their levels of depression and stress during pregnancy, and the consequent impact on the baby. (3) Results: the results obtained show the moderating effects of changes in social support on maternal and paternal stress and depression. Reduced social support during pregnancy is associated with higher levels of stress and depression in both parents and with a high cephalisation index in their babies. (4) Conclusions: special attention should be paid to social support, which can have a strong impact on the evolution of emotional health during pregnancy and concomitantly on the development of the baby.

Published
2022
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2. Oropharyngeal Colostrum Positively Modulates the Inflammatory Response in Preterm Neonates

Author

Francisca Martín-Peregrina, Estefania Martin-Alvarez, José Maldonado-Lozano, Jose A. Hurtado‐Suazo, Julio J. Ochoa, Laura Serrano-López, Manuela Peña-Caballero, Jorge Moreno-Fernandez, Belen Sánchez-Martínez, Mercedes Alonso-Moya, and Javier Díaz-Castro

Subjects
Breastfeeding, Physiology, lcsh:TX341-641, Infant, Premature, Diseases, premature neonates, Enteral administration, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Enteral Nutrition, Swallowing, Pregnancy, 030225 pediatrics, Medicine, Humans, 030212 general & internal medicine, Inflammation, Nutrition and Dietetics, Milk, Human, business.industry, Colostrum, Infant, Newborn, Interleukin, clinical outcomes, Parenteral nutrition, Treatment Outcome, colostrum administration, inflammation, Infant, Extremely Premature, Gestation, Cytokines, Female, business, lcsh:Nutrition. Foods and food supply, Biomarkers, Food Science
Abstract

During the first days of life, premature infants have physiological difficulties swallowing, thereby missing out on the benefits of breastfeeding. The aim of this study is to assess the effects of oropharyngeal mother&rsquo, s milk administration in the inflammatory signaling of extremely premature infants. Neonates (n = 100) (&lt, 32 week&rsquo, s gestation and/or &lt, 1500 g) were divided into two groups: mother&rsquo, s milk group (n = 48), receiving 0.2 mL of oropharyngeal mother&rsquo, s milk every 4 h for the first 15 days of life, and a control group (n = 52), not receiving oropharyngeal mother&rsquo, s milk. Serum concentrations of interleukin (IL) IL-6, IL-8, IL-10, IL-1ra, tumor necrosis factor alpha (TNF-&alpha, ), and interfer&oacute, n gamma (IFN-&gamma, ) were assessed at 1, 3, 15, and 30 days of postnatal life. Maternal and neonatal outcomes were collected. The rate of common neonatal morbidities in both groups was similar. The mother&rsquo, s milk group achieved full enteral feeding earlier, and showed a decrease in Il-6 on days 15 and 30, in IL-8 on day 30, and in TNF-&alpha, and INF-&gamma, on day 15, as well as an increase in IL-1ra on days 3 and 15 and in IL-10 on day 30. Oropharyngeal mother&rsquo, s milk administration for 15 days decreases the pro-inflammatory state of preterm neonates and provides full enteral nutrition earlier, which could have a positive influence on the development of the immune system and inflammatory response, thereby positively influencing other developmental outcomes.

Published
2020

3. [In Process Citation]

Author

Estefanía, Martín Álvarez, María Victoria, Jiménez Cabanillas, Manuela, Peña Caballero, Laura, Serrano López, Naroa, Kajarabille, Javier, Díaz Castro, Julio José, Ochoa Herrera, and José, Maldonado Lozano

Subjects
Male, Milk, Human, Colostrum, Infant, Newborn, Humans, Infant, Infant, Very Low Birth Weight, Oropharynx, Female, Infant, Premature, Immunoglobulin A
Abstract

Introducción: el recién nacido prematuro de muy bajo peso (RNMBP) es inmunológicamente inmaduro y además presenta una alteración de las barreras naturales de defensa. Objetivo: evaluar los efectos que pueda tener la administración de calostro orofaríngeo, administrado durante los primeros 15 días posnatales, sobre los niveles de inmunoglobulina A (IgA) sérica en recién nacidos prematuros de muy bajo peso durante el primer mes de vida. Material y métodos: se desarrolló un estudio de intervención no aleatorizado con grupo control, en el que se incluyeron 38 recién nacidos con ≤ 32 + 6 semanas de gestación y/o menores de 1.500 g de peso. Los sujetos recibieron 0,2 ml de calostro de su madre cada 4 h, iniciándose el procedimiento en las primeras 24 h de vida hasta el 15.o día postnatal. Se midieron los niveles de IgA en la sangre al nacimiento, 3. er , 15.o y 30.o días de vida. Se registraron datos perinatales al nacimiento y durante el periodo de seguimiento. Resultados: IgA sérica aumentó de forma estadísticamente significativa en el grupo de intervención (M1 15,84 μg/ml, M2 20,07 μg/ml, M3 23,65 μg/ml, M4 30,34 μg/ml, p 0,001) y en el grupo control (M1 12,48 μg/ml, M2 16,48 μg/ml, p 0,018; M3 19,41 μg/ml, M4 22,48 μg/ml, p 0,001). Al mes de vida, los niveles de IgA sérica fueron significativamente mayores en el grupo de intervención que en el grupo control (p 0,026). Conclusiones: este estudio sugiere que la administración de calostro orofarínge.

Published
2016

4. Cognitive Functioning and Academic Achievement in Children Aged 6-8 Years, Born at Term After Intrauterine Growth Restriction and Fetal Cerebral Redistribution

Author

José Maldonado-Lozano, Setefilla López-Criado, Miguel Ángel Díaz-López, and Mercedes Bellido-González

Subjects
Male, congenital, hereditary, and neonatal diseases and abnormalities, Pediatrics, medicine.medical_specialty, Multivariate analysis, Intrauterine growth restriction, Academic achievement, Logistic regression, Umbilical Arteries, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, 030225 pediatrics, Developmental and Educational Psychology, medicine, Humans, Risk factor, Child, reproductive and urinary physiology, Retrospective Studies, 030219 obstetrics & reproductive medicine, Fetal Growth Retardation, Infant, Newborn, Cognition, Odds ratio, Cerebral Arteries, medicine.disease, Achievement, female genital diseases and pregnancy complications, embryonic structures, Pediatrics, Perinatology and Child Health, Cohort, Educational Status, Female, Psychology, Cognition Disorders
Abstract

Objective To determine whether cerebroplacental ratio, an indicator of fetal cerebral redistribution (FCR), predicts adverse results for neurodevelopment in intrauterine growth restriction (IUGR) infants. Methods In a cohort of 5,702 infants, 64 were IUGR born at term with FCR. Five were excluded. Of the remainder, 32 presented an abnormal cerebroplacental ratio (IUGR-A) and 27 a normal one (IUGR-B). The controls were 61 appropriate-for-gestational-age children. Cognitive and academic outcomes and the odds ratio of lower academic scores were assessed by multivariate analysis of covariance and logistic regression. Results IUGR-A children presented deficits in cognitive functioning and academic achievement in all domains. IUGR-B children presented slight deficits. Suboptimal cognitive functioning in IUGR-A was more marked in working memory. Abnormal cerebroplacental ratio predicted low academic scores in IUGR-A. Conclusions FCR is a risk factor for IUGR infants, and cerebroplacental ratio identifies those most severely affected. Intervention programs may produce benefits in early-middle childhood.

Published
2016

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