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Background and Aims: Cardiovascular diseases are the leading causes of morbidity and mortality in chronic kidney disease (CKD) patients. Our aim was to derive predictors of cardiac morbidity, mortality, cardiac complications and to develop/validate a scoring tool in patients with CKD undergoing non-cardiac surgery. Methods: A prospective observational multicentre study was done on 770 patients with CKD. The primary outcome ('Event') was one or more than one of sudden cardiac death, pulmonary oedema, acute coronary syndrome, arrhythmia and 30-day mortality. Secondary outcome was hypertension and hypotension. Predictors of cardiac risk were identified. A scoring tool was developed on the 2018 dataset and was validated on the 2019 dataset. Results: The overall incidence of cardiac events was 290 (37.66) whereas the incidence of major adverse cardiac and cerebrovascular events was 15.04. Mortality due to cardiac cause was 13 (1.68). On multivariate regression analysis, seven perioperative variables had significant association with increased risk of events: age > 65 years (P = 0.004), metabolic equivalents (METS) ≤4 (P≤0.032), emergency surgery (P =0.032), mean arterial pressure >119 (P = 0.001), echocardiographic scoring (P = 0.054), type of anaesthesia (P ≤ 0.0001) and type of surgery (P = 0.056). Using these variables, a risk stratification tool was developed. C statistics showed favourable predictive accuracy (0.714) and the model showed good calibration. Conclusion: This risk scoring tool based on preoperative variables will help to predict the risk of events in high-risk CKD patients undergoing non-cardiac surgery. This will help in better counselling and optimisation. Keywords: Cardiovascular diseases, death,sudden cardiac, perioperative care, renal insufficiency chronic, risk assessment, Author(s): Alka Sachin Deo (corresponding author) [1]; Rijuta Kashyapi [2]; Veena Joshi [3]; Parimala Balakundi [1]; Padmalatha Raman [1] INTRODUCTION Cardiovascular complications after non-cardiac surgeries are major contributors to postoperative [...]

The article presents a study on the effect of different surface sterilization methods and different plant growth regulators on culture establishment from Pomegranate nodal explants of cv. Bhagwa. Topics discussed include selection of planting material, collection of explants and sterilization, and effect of different sterilizing agents and media with growth regulators on nature of microbial contamination.

The article presents a study on the effect of bio stimulants on growth and yield of green chilli (Capsicum annuum L.) with nine treatments replicated thrice in a Randomized Block Design. Topics discussed include effect of biostimulants on plant height of green chilli at different intervals, effect of biostimulants on leaf width of green chilli at different intervals, and effect of biostimulants on yield of green chilli.

The noble radioactive gas radon and its isotope thoron dominate terrestrial radiation in the indoor environment. These gases eventually disintegrate generating radioactive ions that readily adhere to aerosol particles. This study was conducted in a tectonically active location with significant radon concentrations. The obtained average values of radon mass exhalation and thoron surface exhalation rate from this study are higher than the global average values of 56 mBq kg−1 h−1 and 1000 mBq m−2 s−1, respectively. As the exhalation rates are higher, naturally the average radon and thoron concentrations are also greater than the worldwide average values of 40 and 10 Bq m−3, respectively. No significant correlation was observed between 222Rn and 220Rn exhalation rate and indoor 222Rn/220Rn concentration. The exposure dose due to 222Rn, 220Rn and their progenies shows no significant health risk. [ABSTRACT FROM AUTHOR]