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2. Cutaneous Lymphomas

Author

Junkins-Hopkins, Jacqueline M., Lin, Fan, editor, Prichard, Jeffrey W., editor, Liu, Haiyan, editor, and Wilkerson, Myra L., editor

Published
2022
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5. Hyperkeratotic variant of porokeratosis in a patient with Hepatitis C virus infection and a concomitant immunosuppressed state

Author

Parekh, Vishwas, Kabihting, Filamer D, and Junkins-Hopkins, Jacqueline M

Subjects
porokeratosis, Hepatitis C virus skin, immunosuppression skin
Abstract

Porokeratoses are acquired and hereditary disorders of keratinization that share a distinctive lesion characterized by raised keratotic borders corresponding histologically to an angled column of parakeratotic cells, called a cornoid lamella. Although a precise mechanistic explanation is lacking, ultraviolet radiation and immunosuppressed states are considered causally-associated with most cases of acquired porokeratosis. Hepatitis C virus (HCV) infection has been proposed as a link between the immunosuppressed states and development of acquired porokeratosis. Among the various recognized clinical entities that constitute this group, rare cases of hyperkeratotic variants have been described that may pose a diagnostic challenge. Herein we describe a remarkable case of the hyperkeratotic variant of porokeratosis that occurred in a patient with known HIV and HCV infections and a coexisting therapy-related immunosuppressed state. We also provide a review of the relevant literature.

Published
2015

8. Amicrobial pustulosis of the folds: A case report of a rare variant of neutrophilic dermatosis associated with systemic lupus erythematosus.

Author

Varano, Alison T., McKinley, Timothy D., and Junkins‐Hopkins, Jacqueline M.

Subjects
SYSTEMIC lupus erythematosus, AUTOIMMUNE diseases, MEDICAL screening, YOUNG women
Abstract

Amicrobial pustulosis of the folds (APF) is a rare neutrophilic dermatosis found in association with autoimmune diseases. We present a 49‐year‐old woman with a history of systemic lupus erythematosus and a recurrent pustular eruption in the cutaneous folds. Histologic examination revealed spongiform pustulosis and dermal neutrophilic infiltrate. The Gram and periodic acid–Schiff stains were negative for bacteria and fungi. A diagnosis of amicrobial pustulosis of the folds was given. While there is no standard treatment, our patient's symptoms resolved following an oral prednisone taper and have not recurred since starting colchicine. The presence of pustules and erosive plaques in skin folds in young women with autoimmune conditions should raise suspicion for APF. The combination of localized neutrophilic spongiosis with intraepidermal or subcorneal pustules in conjunction with dermal changes of a neutrophilic dermatosis is a helpful clue to the diagnosis. If the patient does not already have a diagnosis of an underlying autoimmune condition, a presentation of APF should prompt further screening consisting of a relevant review of symptoms and appropriate assessment for autoimmune antibodies, since APF may precede the diagnosis of autoimmune disorders. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Lymphomatoid papulosis

Author

Klein, Rachel S., primary, Singer, Elisha, additional, Junkins-Hopkins, Jacqueline M., additional, Vittorio, Carmela C., additional, Rook, Alain H., additional, and Kim, Ellen J., additional

Published
2018
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11. List of Contributors

Author

Abdullah, Anthony, primary, Abrouk, Michael, additional, Ahad, Tashmeeta, additional, Ahmed, Imtiaz, additional, Al Hammadi, Anwar, additional, Allen, Caroline, additional, Almohssen, Amer Ali, additional, Alwan, Wisam, additional, Ameen, Mahreen, additional, Amini, Sadegh, additional, Anderson, Bryan E., additional, Anhalt, Grant J., additional, Baker, Donald J., additional, Bala, Harini Rajgopal, additional, Baltz, Julia, additional, Banach, David, additional, Banfield, Cedric C., additional, Baran, Robert, additional, Bardhan, Ajoy, additional, Barkham, Melissa C., additional, Bello, Ysabel M., additional, Benton, Emma, additional, Bergfeld, Wilma F., additional, Berkowitz, Eric, additional, Berman, Brian, additional, Bernhard, Jeffrey D., additional, Bernstein, Daniel, additional, Berth-Jones, John, additional, Bhate, Chinmoy, additional, Bhatia, Bhavnit K., additional, Blume, Jonathan E., additional, Bordet, Nevianna, additional, Borysiewicz, Catherine, additional, Brauner, Gary J., additional, Brodell, Robert T., additional, Brown, Marc D., additional, Burd, Robert M., additional, Burdick, Anne E., additional, Butala, Niraj, additional, Callen, Jeffrey P., additional, Camacho, Ivan D., additional, Camasmie, Helena, additional, Caplivski, Daniel, additional, Cappell, Mitchell S., additional, Casey, Genevieve A., additional, Chan, Lawrence S., additional, Chan, Loi-Yuen, additional, Chen, Jennifer K., additional, Chen, Chen “Mary”, additional, Chiang, Nicole Yi Zhen, additional, Chiaravalloti, Anthony J., additional, Child, Fiona J., additional, Chu, Anthony C., additional, Clayton, Timothy H., additional, Cohen, Steven R., additional, Cooper, Elizabeth A., additional, Cooper, Susan M., additional, Collier, Nick, additional, Correnti, Christina M., additional, Coulson, Ian H., additional, Council, M. Laurin, additional, Cowper, Shawn E., additional, Craven, Nicholas M., additional, Creamer, Daniel, additional, Cruz, Ponciano D., additional, Cusack, Carrie Ann R., additional, Daunton, Adam, additional, Davis, Mark D.P., additional, Dawe, Robert S., additional, D’Cruz, David P., additional, de Berker, David, additional, DeHoratius, Danielle M., additional, Deng, Min, additional, Desai, Seemal R., additional, Devlin, Georgina, additional, DiGiovanna, John J., additional, Doctoroff, Alexander, additional, Dodiuk-Gad, Roni P., additional, Eichenfield, Dawn Z., additional, Eichenfield, Lawrence F., additional, Eisen, Drore, additional, Eke, Ure, additional, Elston, Dirk M., additional, Emanuel, Patrick O.M., additional, Enos, Clinton W., additional, Ensanyat, Shaheen H., additional, Falabella, Anna F., additional, Farberg, Aaron S., additional, Feigenbaum, Lawrence S., additional, Fernandez, Kristen Heins, additional, Fett, Nicole, additional, Finlay, Andrew Y., additional, Firoz, Bahar F., additional, Firoz, Elnaz F., additional, Fitzpatrick, James E., additional, Flischel, Amy E., additional, Foley, Kelly A., additional, Freedman, Derek, additional, Fremlin, Georgina A., additional, Fried, Richard, additional, Friedlander, Philip, additional, Friedman, Adam, additional, Forrestel, Amy K., additional, Fuchs, Brian S., additional, Gach, Joanna E., additional, Galan, Anjela, additional, Ganesh, Jaya, additional, Garg, Amit, additional, Geller, Lauren, additional, Gelmetti, Carlo M., additional, Ghazi, Elizabeth, additional, Ghunawat, Sneha, additional, Goldberg, Leonard H., additional, Goodfield, Mark J.D., additional, Gordon, Marsha L., additional, Gowda, Asha, additional, Grabell, Daniel A., additional, Grant, Matthew, additional, Grattan, Clive E.H., additional, Greaves, Malcolm W., additional, Green, Justin J., additional, Griffiths, Christopher E.M., additional, Gropper, Charles A., additional, Grossberg, Anna L., additional, Gupta, Aditya K., additional, Hadi, Ali S., additional, Hadi, Suhail M., additional, Hagans, Iris A., additional, Hairston, Bethany R., additional, Halpern, Analisa Vincent, additional, Halverstam, Caroline, additional, Harper, Natasha, additional, Harries, Matthew J., additional, Harris, John, additional, Harrison, Shannon, additional, Hatch, Michael M., additional, Heagerty, Adrian H.M., additional, Hebert, Adelaide A., additional, Helms, Stephen E., additional, Hexsel, Camile L., additional, Hexsel, Doris M., additional, Heymann, Warren R., additional, Higgins, Elisabeth M., additional, Higgins, Claire L., additional, High, Whitney A., additional, Hönigsmann, Herbert, additional, Horenstein, Marcelo G., additional, Hruza, George J., additional, Hui, Andrea, additional, Huo, Ran, additional, Ibbotson, Sally H., additional, Ibrahim, Sherrif F., additional, Ilchyshyn, Andrew, additional, Ismail, Dina, additional, Jablonska, Stefania, additional, Jacobe, Heidi T., additional, James, William D., additional, Javed, Aysha, additional, Jemec, Gregor B.E., additional, Johnston, Graham A., additional, Jones, Stephen K., additional, Junkins-Hopkins, Jacqueline M., additional, Kaffenberger, Jessica, additional, Kane, Kelly R., additional, Kanelleas, Antonios, additional, Karadağ, Ayşe Serap, additional, Karas, Laura, additional, Katugampola, Ruwani P., additional, Katz, Bruce E., additional, Kellen, Roselyn, additional, Khan, Murtaza, additional, Khorasani, Hooman, additional, Kim, Ellen J., additional, Kim, Hee J., additional, Kirby, Brian, additional, Kirby, Joslyn S., additional, Klein, Rachel S., additional, Kleydman, Kate, additional, Koch, Dimitra, additional, Kohorst, John J., additional, Koo, John Y.M., additional, Kopp, Sandra A., additional, Korman, Neil J., additional, Kovarik, Carrie, additional, Kraemer, Kenneth H., additional, Krafchik, Bernice R., additional, Krishnamurthy, Karthik, additional, Kvernebo, Knut, additional, Lam, Charlene, additional, Lambert, Peter C., additional, Langtry, James A.A., additional, Larian, Amir A., additional, Larocca, Cecilia A., additional, Lawlor, E. Frances, additional, Lawrence, Clifford M., additional, Lebwohl, Mark G., additional, Lebwohl, Oscar, additional, Lehman, Julia S., additional, Leslie, Tabi A., additional, Lessin, Stuart R., additional, Levitt, Jacob O., additional, Lewis, Fiona M., additional, Liaqat, Maryam, additional, Liu, Kristina J., additional, Loosemore, Michael P., additional, Luger, Thomas A., additional, Lupi, Omar, additional, Lushniak, Boris D., additional, Lyon, Calum C., additional, Maderal, Andrea D., additional, Mahmoud, Bassel H., additional, Majewski, Slawomir, additional, Mallett, Richard B., additional, Manders, Steven M., additional, Mann, Ranon, additional, Mansouri, Yasaman, additional, Margolis, David J., additional, Markowitz, Orit, additional, Marsland, Alexander, additional, Martin-Clavijo, Agustin, additional, Martinez, Daniela, additional, Matiz, Catalina, additional, Maurer, Marcus, additional, McKerrow, Kevin, additional, Meah, Nekma, additional, Micali, Giuseppe, additional, Micheletti, Robert G., additional, Millard, Leslie G., additional, Miller, James E., additional, Wong Millsop, Jillian W., additional, Mimouni, Daniel, additional, Mirowski, Ginat W., additional, Mirza, Sultan A., additional, Molin, Sonja, additional, Morales-Burgos, Adisbeth, additional, Morison, Warwick L., additional, Mørk, Cato, additional, Morton, Colin A., additional, Motley, Richard J., additional, Mowbray, Megan, additional, Muldoon, Eavan G., additional, Muncaster, Anna E., additional, Murakawa, George J., additional, Murase, Jenny E., additional, Murdoch, Michele E., additional, Nabatian, Adam S., additional, Nakamura, Mio, additional, Nalluri, Rajani, additional, Nawas, Zeena Y., additional, Needham, Glen R., additional, Newell, Glenn C., additional, Newton-Bishop, Julia, additional, Nguyen, Adam V., additional, Nixon, Rosemary L., additional, O’Brien, Jack C., additional, Ogden, Stephanie, additional, Olbricht, Suzanne M., additional, O’Shea, Sally Jane, additional, Owen, Cindy E., additional, Pan, Michael, additional, Pappas-Taffer, Lisa, additional, Parish, Jennifer L., additional, Parish, Lawrence Charles, additional, Payette, Michael, additional, Peck, Gary L., additional, Pena, Sandra, additional, Peranteau, Jarad, additional, Pereira, Frederick A., additional, Perkins, William, additional, Perlis, Clifford S., additional, Phelps, Robert G., additional, Phillips, Tania J., additional, Poh-Fitzpatrick, Maureen B., additional, Pomeranz, Miriam Keltz, additional, Pop, Samantha R., additional, Porcu, Pierluigi, additional, Powell, James B., additional, Prok, Lori D., additional, Pyle, Tia M., additional, Qazaz, Surod, additional, Rajkomar, Vikram, additional, Rashid, Rabia S., additional, Rashighi, Mehdi, additional, Ratnavel, Ravi, additional, Regula, Christie G., additional, Renzi, Michael, additional, Revuz, Jean, additional, Reynolds, Rachel V., additional, Richard, Elisabeth, additional, Richard, Gabriele, additional, Rigel, Darrell S., additional, Robles, Wanda Sonia, additional, Rogge, Megan, additional, Rook, Alain H., additional, Manning, Jamie R., additional, Rosen, Ted, additional, Rosenbach, Misha, additional, Rosenfeld, David, additional, Rowland Payne, Christopher, additional, Rubin, Adam I., additional, Rubin, Courtney, additional, Rustin, Malcolm H.A., additional, Ruzicka, Thomas, additional, Samimi, Sara, additional, Schachner, Lawrence A., additional, Scheinfeld, Noah, additional, Schlosser, Bethanee J., additional, Schnur, Rhonda E., additional, Schwartz, Robert A., additional, Scorer, Matthew J., additional, Selkin, Bryan A., additional, Seymour, Jamie, additional, Shaver, Christine M., additional, Shea, Christopher R., additional, Shear, Neil H., additional, Shim, Tang Ngee, additional, Shimizu, Hiroshi, additional, Siegel, Julia, additional, Singer, Elisha, additional, Skelsey, Maral Kibarian, additional, Sladden, Chris, additional, Sladden, Michael, additional, Smith, Janellen, additional, Smucker, Joanne E., additional, Somani, Najwa, additional, Sommer, Lacy L., additional, Sommerlad, Mary, additional, Soon, Christine, additional, Sopkovich, Jennifer A., additional, Soter, Nicholas A., additional, Spencer, James M., additional, Staughton, Richard C.D., additional, Sterling, Jane C., additional, Sunderkötter, Cord, additional, Taibjee, Saleem M., additional, Tamura, Deborah, additional, Tan, Eunice, additional, Tang, William Y-M., additional, Taylor, Lynsey, additional, Thiers, Bruce H., additional, Thomas, Lucy J., additional, Thornton, Cody R., additional, Tobin, Anne-Marie, additional, Torgerson, Rochelle R., additional, Tosti, Antonella, additional, Tsatsou, Fragkiski, additional, Tsuji-Abe, Yukiko, additional, Tucker, William F.G., additional, Tyring, Stephen K., additional, Udkoff, Jeremy, additional, Unger, Robin H., additional, Unger, Walter P., additional, Utz, Sarah, additional, Valbuena, Martha C., additional, van de Kerkhof, Peter, additional, Van Voorhees, Abby S., additional, Vangipuram, Ramya, additional, Veitch, David, additional, Venning, Vanessa, additional, Versteeg, Sarah G., additional, Viera, Martha, additional, Vittorio, Carmela C., additional, Vleugels, Ruth Ann, additional, Wali, Gorav N., additional, Wallengren, Joanna, additional, Wan, Joy, additional, Wanat, Karolyn A., additional, Weichert, Gabriele, additional, Weidmann, Anja K., additional, Weinberg, Jeffrey M., additional, Werth, Victoria P., additional, White, Lucile E., additional, Wiener, Adam H., additional, Wilkin, Jonathan K., additional, Wilkin, Nathaniel K., additional, Williams, Jason, additional, Wilson, Niall, additional, Wiss, Karen, additional, Witkowski, Joseph A., additional, Wiznia, Lauren E., additional, Wong, Henry K., additional, Wong, Junie Li Chun, additional, Wright, Andrew L., additional, Wriston, Cooper C., additional, Wu, Benedict C., additional, Wulkan, Adam, additional, Zaenglein, Andrea L., additional, Zaki, Irshad, additional, Zeichner, Joshua A., additional, Zhu, Tian Hao, additional, Zone, John J., additional, Zouboulis, Christos C., additional, and Zuberbeir, Torstein, additional

Published
2018
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12. Localized argyria with pseudo‐ochronosis: A report of two cases highlighting involvement of elastic fibers.

Author

Clark, Abigale, Kosik, Grace, Desrosiers, Andrew, Tjarks, B. Joel, and Junkins‐Hopkins, Jacqueline M.

Subjects
FIBERS, NEVUS, METALWORK, SWEAT glands, TOPICAL drug administration, FIBER orientation
Abstract

Localized argyria with pseudo-ochronosis: A report of two cases highlighting involvement of elastic fibers Pseudo-ochronosis in localized argyria was first reported in 2002,[1] when they described ochre-colored swollen homogenized collagen bundles seen on biopsy of localized argyria in the absence of the typical causes of ochronosis. Keywords: argyria; elastic fibers; localized argyria; pseudo-ochronosis EN argyria elastic fibers localized argyria pseudo-ochronosis 815 818 4 08/16/23 20230901 NES 230901 INTRODUCTION Argyria, either localized or generalized, is a rare dermatologic condition where the deposition of silver within skin or mucous membranes results in grayish-blue pigmentation that can be appreciated clinically. [Extracted from the article]

Published
2023
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19. Reactive infectious mucocutaneous eruption due to COVID‐19 with erythema‐multiforme‐like lesions and myeloid cells.

Author

Ortiz, Eduardo G. and Junkins‐Hopkins, Jacqueline M.

Subjects
*ORAL mucosa, *MYELOID cells, *ERYTHEMA multiforme, *COVID-19, *RHYME, *MYELOPEROXIDASE
Abstract

Reactive infectious mucocutaneous eruption (RIME) is a recently described entity in which there is prominent mucositis, most commonly involving the oral and urogenital mucosa, secondary to a variety of pathogens. There is typically minimal cutaneous involvement in RIME. This contrasts with erythema multiforme (EM) in which characteristic targetoid lesions predominate, usually in isolation (EM minor), but in a subset of cases, with severe mucositis (EM major). While the histopathologic features of RIME have not been as well defined, those of EM are characterized by epidermal apoptosis and interface dermatitis with lymphocytes making up the predominant cell type. We report a unique case of RIME in a 16‐year‐old male with COVID‐19 characterized by significant mucositis involving the oral and genital mucosa, as well as numerous targetoid lesions on the trunk and extremities. Histopathologically, there was an inflammatory infiltrate obscuring and disrupting the epidermal interface, associated with epidermal necrosis, and blister formation. The infiltrate was composed of cells with irregular, non‐segmented and elongate nuclei, with myeloid and histiocytoid cytomorphology. The cells were positive for myeloperoxidase, CD68, and CD163 (subset) suggesting myeloid lineage. RIME is a rarely reported COVID‐19‐related eruption, and targetoid lesions and myeloid interface reactions have not been described with RIME. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Pseudoepitheliomatous Hyperplasia in a Red Pigment Tattoo: A Separate Entity or Hypertrophic Lichen Planus-like Reaction?

Author

Kazlouskaya, Viktoryia and Junkins-Hopkins, Jacqueline M.

Subjects
stomatognathic diseases, stomatognathic system, integumentary system, Brief Report, skin and connective tissue diseases
Abstract

Red pigment tattoos are known to cause pseudoepitheliomatous hyperplasia in the skin, frequently simulating squamous cell carcinoma or keratoacanthoma. Herein, the authors present two additional cases of red pigment tattoo pseudoepitheliomatous hyperplasia in which they noted a lichenoid tissue reaction. They reviewed the previously published cases and observed a lichenoid reaction in the histopathological images similar to hypertrophic lichen planus. The authors suggest that these reactions might best be referred to as "lichenoid reaction with pseudoepitheliomatous hyperplasia" or "hypertrophic lichen planus-like reaction." Accordingly, recognition of an inflammatory component may allow additional treatment options.

Published
2015

34. Treatment of Skin Disease Previous Edition Contributors

Author

Abrouk, Michael, Accordino, Robert E., Admani, Shehla, Adriaans, Beverly, Agarwal, Sanjay, Ahad, Tashmeeta, Ahmed, Imtiaz, Akhavan, Arash, Al Quran, Hanadi Abdallah, Albert, Sandra, Alberta-Wszolek, Lauren, Allen, Caroline, Allen, Robert A., Al-Qari, Haltham, Al-Suwaidan, Sami, Alwan, Wisam, Amini, Sadegh, Angit, Caroline, Anhalt, Grant J., Anyanwu, Cynthia O., Aouthmany, Mouhammad, Asch, Sarah, Ashourian, Neda, Ashton, Richard, Aslam, Arif M., Bader, Eanas, Bain, E. Eugene, III, Bakkour, Waseem, Bala, Harini Rajgopal, Balasubramaniam, Periasamy, Baltz, Julia, Banerjee, Abhijit, Bank, Ali, Bardhan, Ajoy, Bartlett, Brenda L., Bartsch, Megan, Basu, Tanya N., Belazarian, Leah, Bello, Ysabel M., Benton, E. Claire, Berbis, Philippe, Berger, Jeffrey, Berkowitz, Eric, Bernhard, Jeffrey D., Bernstein, Daniel, Bewley, Anthony, Bhushan, Monica, Bialy, Tracy, Bibi, Yuval, Bilsland, David J., Blackwell, Verity, Bornstein, Elana, Borysiewicz, Catherine, Bos, Jan D., Bowman, Paul H., Brauner, Gary J., Brooke, Rebecca C.C., Bruce, Alison J., Buchholz, Robin, Burd, Robert M., Burge, Susan M., Byrd-Miles, Katina, Campbell, Caren, Carruthers, Robert, Carucci, John A., Castelo-Soccio, Leslie, Cave, Bridgette, Centurion, Santiago A., Chachkin, Samuel L., Chadwick, Preston W., Chalmers, Robert J.G., Chang, Yuchl C., Chayavichitsilp, Pamela, Chen, Chen “Mary”, Cheung, Lawrence, Zhen Chiang, Nicole Yi, Chiaravalloti, Anthony J., Chong, Alvin H., Chu, Anthony C., Clark, Sheila M., Clayton, Timothy H., Cliff, Sandeep H., Cockrell, Clay J., Conrad, Nicole, Cooper, Susan M., Correnti, Christina M., Council, M. Laurin, Cowper, Shawn E., Cox, Neil H., Craven, Nicholas M., Creamer, Daniel, Cunliffe, William, Curry, Mary L., Dalton, Jack F., Dasgeb, Bahar, Davis, Rosie, Dawber, Rodney, Deng, Min, Desai, Avani D., Desai, Nisha C., Devlin, Georgina, Diamantis, Stephanie A., Diaz, Camilo, Dick, Sarah E., DiRusso, Lori M., Doctoroff, Alexander, Dortzbach, Kathryn, Dowd, Pauline, Drage, Lisa A., Dyche, Jacqueline A., Eke, Ure, Ellis, Natalie N., Emer, Jason J., Eminger, Lindsay A., Ensanyat, Shaheen H., Faergemann, Jan, Falabella, Anna F., Fanelli, Matthew, Farquharson, Nina R., Farsani, Terry T., Feingold, Anat, Felner, Alyssa M., Ferguson, James, Fernández, Geover, Ferzli, Pascal G., Fiandeiro, Pamela, Firoz, Elnaz F., Fischer, Michael, Fitzpatrick, James E., Fleischmayer, Raul, Frankel, Stacey, Friedlander, Philip, Fuchs, Brian S., Gagna, Claude E., Levine, Erika Gaines, Galan, Anjela, Galaria, Noreen Ahmad, Gamboni, Sarah E., Gardner, Loma S., Garg, Amit, Garza, Reed M., Gelfand, Joel M., Geller, Lauren, Gelmetti, Carlo M., Ghazi, Elizabeth, Ghunawat, Sneha, Ghura, Harvinder, Gibbs, Sam, Gibson, Gillian E., Goldenberg, Gary, Gonzales, Darrell W., Goodfield, Mark J.D., Gordon, Marsha L., Gordon, Patricia Mary, Gordon, Rachel A., Grabell, Daniel A., Graham-Brown, Robin A.C., Greaves, Malcolm W., Green, Justin J., Grelck, Kurt W., Griffiths, Christopher E.M., Gropper, Jaime R., Gruber, Pascale, Guidry, Jacqueline A., Gupta, Arpeta, Gupta, Girish, Gurtman, Alejandra, Hadi, Ahmed S., Hafejee, Abdul, Hague, Joanne, Haimowitz, Julia E., Handfield-Jones, Susan E., Zhu, Tian Hao, Harper, Natasha, Harper, John, Harris, Ronald M., Harrison, Shannon, Hatch, Michael M., Hawk, John L.M., Heagerty, Adrian H.M., Fernandez, Kristen Heins, Helms, Amy E., Henderson, Catriona A., Henry, Patricia A., Higgins, Claire L., Higgins†, Elisabeth M., Hodulik, Sarah, Hönigsmann, Herbert, Houk, Laura, Houpt, Karen R., Hruza, George J., Hui, Andrea, Humphreys, Frances, Huo, Ran, Hwang, Linda Y., Ilchyshyn, Andrew, Ilyas, Erum N., Ismail, Dina, Jablonska, Stefania, Javed, Aysha, Jing, Wei, Jolliffe, Victoria, Jones, Stephen K., Jorizzo, Joseph L., Junkins-Hopkins, Jacqueline M., Kaffenberger, Jessica, Kamenshchikov, Aleksey, Kannee, Carmen E., Kantor, Jonathan, Kasparis, Christos, Kaur, Manjit, Kaye, Keith, Kazlow, Dana, Keefe, Martin, Kellen, Roselyn, Khan, Murtaza, Kia, Kevin F., Skelsey, Maral Kibarian, Kihiczak, George G., Kim, Ho Jin, Kim, Sam, Kirby, Brian, Kirtschig, Gudula, Klein, Rachel S., Kleinerman, Rebecca, Kleydman, Kate, Kluk, Justine, Knopp, Eleanor A., Knowles, Sandra R., Kohorst, John J., Kopf, Alfred W., Korman, Neil J., Krafchik, Bernice R., Krishnan, Anjeli, Krupnick, Amy, Kupetsky, Erine A., Lamba, Sumedha, Lambert, W Clark, Langmuir, Peter, Langtry, James A.A., Larian, Amir A., Larocca, Cecilia A., Lawrence, Clifford M., Layton, Alison, Lee, Andrew D., Lee, Chai Sue, Lee, Robert E., Lessin, Stuart R., Levin, Joshua M., Levin, Robin M., Li, Hong, Liu, Kristina J., Loftus, Frances, Loosemore, Michael P., Lui, Edward, Lushniak, Boris D., Macedo, Chrystalla, Maderal, Andrea D., Mailhot, Jeffrey, Majewski, Slawomir, Majmudar, Vallari, Mann, Ranon, Manning, Jamie R., Mansouri, Yasaman, Margolis, David J., Markoff, Sarah, Marks, Ronald, Marmur, Ellen S., Marraiki, Najat A.Y., Marsden, Jeremy R., Marsland, Alexander, Martin-Clavijo, Agustin, Martinez, Anna, Matiz, Catalina, McAllister, Susan Coutinho, McDonagh, Andrew J.G., McFadden, John, McGinnis, Karen S., McKenna, Dermot B., McKerrow, Kevin, Mehmi, Manjeet, Mendonca, Corinna, Metz, Brandie J., Millard, Leslie G., Miller, James E., Miller, Jason H., Millett, Christian R., Milligan, Alex, Mimouni, Daniel, Minni, John, Mirza, Sultan A., Molin, Sonja, Montie, Dwayne, Morales-Burgos, Adisbeth, Morel, Patrice, Morison, Warwick L., Mortimer, Peter S., Motley, Richard J., Mowad, Christen M., Mowbray, Megan, Muncaster, Anna E., Murakawa, George J., Murray, Stuart C., Nabatian, Adam S., Nalluri, Rajani, Nasca, Maria R., Nawas, Zeena Y., Nayeemuddin, Farzana, Nazarlan, Rachel, Neill, Sallie, Newton-Bishop, Julia, Shim, Tang Ngee, Nguyen, Adam V., Nguyer, Patricia, Nousari, Carlos H., O’Brien, Jack C., O’Donoghue, Nuala, O’Driscoll, John B., O’Shea, Sally Jane, Ogboll, Malobl, Ogden, Stephanie, Owen, Caroline M., Paller, Amy, Palmer, Roy A., Pan, Michael, Panting, Katherine, Pappas-Taffer, Lisa, Patalay, Rakesh, Patel, Gopi, Patel, Nisha C., Paul, Jose, Payette, Michael, Piliang, Melissa Peck, Peck, Gary L., Pena, Sandra, Peranteau, Jarad, Pereira, Frederick A., Perkins, William, Perlis, Clifford S., Piraccini, Bianca Maria, Pittelkow, Mark, Pop, Samantha R., Porcu, Pierluigi, Pote, Amy, Powell, James B., Prok, Lori D., Pyle, Tia M., Qazaz, Surod, Rajkomar, Vikram, Rajpar, Sajjad F., Ramirez, Claudia C., Rapini, Ronald P., Ravitskiy, Larisa, Reddick, Tanya, Regula, Christie G., Reynolds, Rachel V., Richard, Elisabeth, Roberts, Brandie J., Roberts, David T., Rogers, Roy S., III, Rogge, Megan, Roling, Daniel, Rosenfeld, David, Payne, Christopher Rowland, Rubin, Adam I., Rubin, Courtney, Rudikoff, Donald, Ruzicka, Thomas, Sahu, Malini, Salvaggio, Heather L., Samimi, Sara, Sanchez, Miguel R., Sapadin, Allen, Scarff, Cate, Schachner, Lawrence A., Scheinfeld, Noah, Schlosser, Bethanee J., Schofield, Olivia M.V., Kirby, Joslyn Sciacca, Segal, Elana T., Selkin, Bryan A., Sexton, Daniel J., Seymour, Jamie, Shaver, Christine M., Shergil, Bav, Siegel, Julia, Silverman, Robert, Singer, Elisha, Singh, Saurabh, Sladden, Chris, Sladden, Michael, Smith, Andrew G., Smucker, Joanne E., Somani, Najwa, Sommerlad, Mary, Soon, Christine, Sopkovich, Jennifer A., Spencer, James M., Spielvogel, Richard L., Stalkup, Jennifer R., Staughton, Richard C.D., Stege, Helger, Sterling, Jane C., Stibich, Adam S., Suchin, Elliot, Suchin, Karen, Summey, Brett T., Jr, Takwale, Anita, Talhari, Carolina, Tan, Jianyou, Tan, Mei-Hing, Tarlow, Mordechai M., Taylor, Lynsey, Telfer, Nicholas R., Ter Poorten, Maryanna C., Thai, Keng-Ee, Thiers, Bruce H., Thomas, Lucy J., Thomson, Michelle A., Thornton, Cody R., Tobin, Anne-Marie, Tremaine, Anne Marie, Tripp, Jackie M., Tristani-Firouzi, Payam, Tsatsou, Fragkiski, Tucker, William F.G., Udkoff, Jeremy, Unger, Robin H., Unger, Walter P., Utz, Sarah, Valbuena, Martha C., Vangipuram, Ramya, Veitch, David, Venning, Vanessa, Versteeg, Sarah G., Vidal, Claudia Irene, Viera, Martha, Vlachou, Christina, Waldorf, Heidi A., Wali, Gorav N., Wallach, Frances, Wan, Joy, Ward, Jon R., Weidmann, Anja K., Wesley, Carlos K., West, Dennis, Wharton, James R., Whittaker, Sean J., Wiener, Adam H., Wilkin, Nathaniel K., Williams, Jason, Boucher, Kari Williamson, Winhoven, Sandra M., Wiss, Karen, Witkowski†, Joseph A., Wojnarowska, Fenella, Wong Millsop, Jillian W., Wong, Henry K., Woodall, Timothy, Wriston, Cooper C., Wu, Benedict C., Wulkan, Adam, Yates, Victoria M., Lam, Wing Yin, Young, Helen S., Zaghloul, Sameh S., Zeichner, Joshua A., Zell, Deborah, and Zouboulis, Christos C.

Published
2022
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38. Two cases of systemic mantle cell lymphoma involving the skin.

Author

Kazlouskaya, Viktoryia, Spizuoco, Amy, and Junkins-Hopkins, Jacqueline M.

Subjects
MANTLE cell lymphoma
Abstract

Mantle cell lymphoma (MCL) is a form of non-Hodgkin lymphoma that rarely affects skin. Cutaneous involvement is non-specific but usually indicates widespread disease. Herein we present two cases of MCL with secondary skin involvement. One case presented as an acneiform eruption on the face and had aberrant expression of bcl-2 and bcl-6 with weak CD5 expression. The second presented with multiple tumors on the abdomen and thighs. In both cases expression of Cyclin-D1 by the tumor cells was seen. Both patients died shortly after the diagnosis was established. [ABSTRACT FROM AUTHOR]

Published
2016
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39. Pseudoepitheliomatous Hyperplasia in a Red Pigment Tattoo.

Author

KAZLOUSKAYA, VIKTORYIA and JUNKINS-HOPKINS, JACQUELINE M.

Subjects
*CELLULAR pathology, *HYPERPLASIA, *EPHEDRINE, *TATTOO removal, *COSMETIC dermatology
Abstract

Red pigment tattoos are known to cause pseudoepitheliomatous hyperplasia in the skin, frequently simulating squamous cell carcinoma or keratoacanthoma. Herein, the authors present two additional cases of red pigment tattoo pseudoepitheliomatous hyperplasia in which they noted a lichenoid tissue reaction. They reviewed the previously published cases and observed a lichenoid reaction in the histopathological images similar to hypertrophic lichen planus. The authors suggest that these reactions might best be referred to as "lichenoid reaction with pseudoepitheliomatous hyperplasia" or "hypertrophic lichen planus-like reaction." Accordingly, recognition of an inflammatory component may allow additional treatment options. [ABSTRACT FROM AUTHOR]

Published
2015

40. Aggressive cutaneous T-cell lymphomas

Author

Junkins-Hopkins, Jacqueline M.

Abstract

Cutaneous T cell lymphomas (CTCLs) are heterogeneous, with a prognosis determined in large part by combined clinical, histopathologic, and immunophenotypic features. They are classified under the WHO-EORTC classification of primary cutaneous lymphoma. Whether or not a patient diagnosed with CTCL will experience an aggressive course may not be completely predictable; however, certain subtypes have been proven to be associated with a poor response to therapy and/or short survival. These aggressive subtypes may be diagnosed by certain histologic, immunophenotypic, and clinical features; however, there are benign lymphoproliferative disorders (LPD), such as lymphomatoid papulosis (LyP) that present with biopsy findings that simulate an aggressive lymphoma. Moreover, some of the well-recognized aggressive lymphomas may rarely follow an indolent course, while otherwise indolent lymphomas may act aggressively. This review will focus on the non-mycosis fungoides (MF) aggressive subtypes, as well as potentially aggressive presentations of MF.

Published
2017
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42. Colaboradores

Author

Al-Rohil, Rami N., Amin, Bijal, Bergfeld, Wilma F., Billings, Steven D., Buehler, Darya, Busam, Klaus J., Carlson, J. Andrew, Celebi, Julide Tok, Chen, Helen M., Clarke, Loren E., Prundeanu Croitoru, Anca G., Francis, Jasmine H., Fullen, Douglas R., Fung, Maxwell A., Granese, Jacqueline, Haskell, Henry, Hu, Stefanie, Junkins-Hopkins, Jacqueline M., Kamino, Hideko, Mahar, Annabelle, Marr, Brian P., Ming, Michael E., Murali, Rajmohan, Myskowski, Patricia L., Nehal, Kishwer S., Prieto, Victor G., Pulitzer, Melissa P., Ramos-e-Silva, Marcia, Requena, Luis, Rongioletti, Franco, Ruben, Beth S., Scolyer, Richard A., Sellheyer, Klaus, Shea, Christopher R., Thompson, John F., Tudisco, Marie, Ubriani, Ravi R., and Wyatt, Angela J.

Published
2018
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43. Cystic acantholytic dyskeratosis of the vulva: An unusual presentation of a follicular adnexal neoplasm.

Author

Torres, Kara Melissa Tiangco and Junkins-Hopkins, Jacqueline M.

Subjects
*DYSKERATOSIS congenita, *KERATOSIS follicularis
Abstract

Acantholytic dyskeratosis (AD) is a histologic pattern seen in Darier's disease or dyskeratosis follicularis, warty dyskeratoma, and transient AD. This pattern is characterized by suprabasilar clefting, acantholysis, and formation of corps ronds and grains. We present a case of AD that is unique based on its genital location and cystic architecture. A 53-year-old woman presented with an otherwise asymptomatic cyst on her left vulva of uncertain duration. On microscopic examination, there were fragments of cystic epithelium with areas of hypergranulosis, acantholysis, corps ronds, and corps grains formation. These features are felt by the authors to be a unique presentation of a follicular adnexal neoplasm. [ABSTRACT FROM AUTHOR]

Published
2016
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44. Multiple nodules on the sole of the foot.

Author

Miceli, Alyssa J., Junkins-Hopkins, Jacqueline M., Elston, Dirk M., and Polley, Dennis C.

Subjects
*FIBROMAS, *MAGNETIC resonance imaging
Abstract

Ledderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive corkscrew morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations. [ABSTRACT FROM AUTHOR]

Published
2015
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45. Contributors

Author

Al-Rohil, Rami N., Amin, Bijal, Bergfeld, Wilma F., Billings, Steven D., Buehler, Darya, Busam, Klaus J., Carlson, J. Andrew, Celebi, Julide Tok, Chen, Helen M., Clarke, Loren E., Croitoru, Anca G. Prundeanu, Francis, Jasmine H., Fullen, Douglas R., Fung, Maxwell A., Granese, Jacqueline, Haskell, Henry, Hu, Stefanie, Junkins-Hopkins, Jacqueline M., Kamino, Hideko, Mahar, Annabelle, Marr, Brian P., Ming, Michael E., Murali, Rajmohan, Myskowski, Patricia L., Nehal, Kishwer S., Prieto, Victor G., Pulitzer, Melissa P., Ramos-e-Silva, Marcia, Requena, Luis, Rongioletti, Franco, Ruben, Beth S., Scolyer, Richard A., Sellheyer, Klaus, Shea, Christopher R., Thompson, John F., Tudisco, Marie, Ubriani, Ravi R., and Wyatt, Angela J.

Published
2016
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46. Polypoid melanoma: a rare clinical subtype frequently confused with benign entities.

Author

Valdebran, Manuel, Wu, Karen N., Wu, Andrew, and Junkins-Hopkins, Jacqueline M.

Subjects
MELANOMA treatment, DERMATOPATHOLOGY
Abstract

Polypoid melanoma represents a distinct variant of melanoma characterized by an ulcerated exophytic nodule. Although this melanocytic tumor is usually restricted to the papillary dermis, it presents with a thick Breslow level and aggressive course. Its rapidly growing vertical phase and its amelanotic nature frequently simulate benign or non-aggressive entities; leading to a delay in biopsy and resulting in an increased risk of metastasis at the time of the diagnosis. [ABSTRACT FROM AUTHOR]

Published
2016
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47. Reduced Expression of RECK Protein May Help Differentiate Cutaneous Malignant Melanoma from Melanocytic Nevus.

Author

Zhang L, Xie Q, Shan SJ, Tabor MK, and Junkins-Hopkins JM

Subjects
Adult, Female, GPI-Linked Proteins genetics, Gene Expression Regulation, Neoplastic, Humans, Male, Melanoma pathology, Middle Aged, Nevus, Pigmented pathology, RNA, Messenger biosynthesis, GPI-Linked Proteins biosynthesis, Melanoma genetics, Nevus, Pigmented genetics
Abstract

Background: Differentiating between vertical growth cutaneous malignant melanoma (CMM) and predominantly intradermal benign melanocytic nevus (BMN) can be extremely challenging. Reversion-inducing cysteine-rich protein with Kazal motifs (RECK) is an endogenous inhibitor of many proteins that promote tumor invasion and progression. We investigated the difference in expression of RECK between CMM and BMN to determine whether RECK could assist in their differentiation., Materials and Methods: The expression of RECK in skin biopsies of 39 cases, including 20 cases of CMM and 19 cases of BMN, was evaluated by immunohistochemistry., Results: Two out of 20 cases (10%) of CMM were positive for RECK, and all (100%) 19 cases of BMN exhibited positivity at different levels. In 7/8 cases of CMM adjacent to benign nevus cells, malignant melanoma cells did not express RECK, but benign nevus cells stained positively., Conclusion: These findings suggest that immunohistochemical staining for RECK could be useful in the differential diagnosis between CMM and BMN., (Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.)

Published
2015

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