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Geriatric assessment is an integral part of geriatrics and leads to various improvements in the treatment of geriatric patients.Analysis of assessment data and patient characteristics in a large inpatient geriatric patient population. Evaluation of data from the Geriatrics in Bavaria Database (GiB-DAT) over 20 years as well as a cross-sectional study from 2020. Presentation of data for patients in inpatient acute geriatrics as well as continuing geriatric rehabilitation.The number of patient records and participating hospitals has steadily increased for both inpatient care types to 821,913 (status 31 March 2021). The Barthel index and other assessment results show differentiated values between acute geriatrics and continuing geriatric rehabilitation.The results demonstrate the differences in patient outcomes between the two types of care as well as changes in the setting over time. The constancy of the applied assessment instruments contributes to the comparability of the different hospitals; however, it is necessary to introduce new and alternative assessment instruments and to further develop inpatient geriatrics.HINTERGRUND: Geriatrisches Assessment ist integraler Bestandteil der Geriatrie und führt zu diversen Verbesserungen in der Behandlung geriatrischer Patienten.Analyse von Assessmentdaten und Patientenmerkmalen in einer großen stationären geriatrischen Patientenpopulation. Auswertung der Daten der Geriatrie in Bayern-Datenbank (GiB-DAT) über einen Zeitraum von 20 Jahren sowie einer Querschnittsuntersuchung aus dem Jahr 2020. Darstellung von Daten für Patienten der stationären Akutgeriatrie sowie der weiterführenden geriatrischen Rehabilitation.Die Zahl der Patientendatensätze und teilnehmende Kliniken ist für beide stationäre Versorgungsformen kontinuierlich angestiegen auf 821.913 (Stand 31. März 2021). Der Barthel-Index und andere Assessmentergebnisse zeigen differenzierte Werte zwischen der Akutgeriatrie und der weiterführenden geriatrischen Rehabilitation.Die Ergebnisse belegen die Unterschiede des Patientengutes beider Versorgungsformen sowie die Änderungen der Rahmenbedingungen im Verlauf. Die Konstanz der angewandten Assessmentinstrumente trägt zur Vergleichbarkeit der verschiedenen Kliniken bei. Andererseits ist es erforderlich, neue und alternative Assessmentinstrumente einzuführen und die stationäre Geriatrie weiterzuentwickeln.

BACKGROUND: In clinical research as well as good clinical practice increasing importance is placed on standardized and evaluated procedures. They provide information which is important for the prognosis, determination of the need for interventions, determination of treatment goals and evaluation of treatment approaches and outcomes. Furthermore, they serve as justification of the reimbursement for presentation to official bodies. Until now no officially authorized German version of the performance-oriented mobility assessment (POMA) according to Tinetti was available. OBJECTIVES: This article presents a methodically translated German version of the POMA that also includes so far partially unpublished instructions for the examiner and the examined person. MATERIAL AND METHODS: The internationally recognized recommendations for the cross-cultural adaptation of health status measures served as the foundation of the translation process. By means of three translations from the original language into the target language a preliminary consensus version was developed, which was then translated back into the original language by two native speakers. RESULTS AND CONCLUSION: With this new and for the first time authorized German translation of the POMA a version of this assessment is available that achieves unification and standardization in German speaking countries and guarantees an improved comparability with international studies. Language: de

The design of medical devices could be applied and developed for new microscopic surgical procedures instead of the traditional surgical procedures.

High salt concentrations in soil water impose osmotic and /or ionic stress and result in changed morphological and development patterns and modified physiological and biochemical processes in plants.

Triple-negative breast cancer (TNBC) represents a diverse group of breast cancers that are characterized by lack of expression of the estrogen receptor (ER), progesterone receptor (PR) and lack of amplification of the human epidermal growth factor (HER2) [1- 2].

The incidence of pituitary adenomas in the population is approximately 1: 1000 [1], which is 15% of all intracranial neoplasms [2].

It is necessary to detect diseases at an early stage since this may minimize harmful effects on the human body.

When looking at since-2016 articles published in the BJSTR, there seem relatively few studies from Western Europe, North America and Australia

Livestock performance and welfare may be adversely affected by weather conditions, heat stress being a sign of deterioration of animal welfare...

Vulvovaginal candidiasis is estimated to be the second most common cause of vaginitis after bacterial vaginosis [1].

Although pain management as core of healing (“Sedare dolorum divinum est”) has been declared by Hippocrates in old ages, the Pain medicine as a field of contemporary medicine exists slightly more than half century.

In the last decade, the rise of nanoparticles (NPs) in commercial products and in biomedical applications has urged the understanding of potential risks and harmful effects induced by their exposure at cellular level due to their biological interactions [1,2].

Frailty is an excess vulnerability to stressors, with a reduced ability to maintain or regain homeostasis after a destabilizing event, leading to poor outcomes: early death, disability, unplanned hospitalization and falls [1,2].

Malignant Glioma (MGs) variants, Glioblastoma (GBM) is the most common malignant tumor in the central nervous system.

Candidiasis is prevalent when the host defense is compromised. For example, individuals with diabetes mellitus, HIV infection, chronic systemic immune-suppressor drugs usage, or patients in intensive care units or having cancer are at high risk to develop persistent candida infection or recurrent episodes [1,2].

The casual association between abnormalities in the fetal development (eg., intrauterine growth restriction (IUGR) or prematurity) and the incidence of chronic conditions (eg., hypertension, coronary artery disease and stroke) in long-term was first proposed by Professor Barker [1,2].

Case reports describing disseminated Herpes simplex virus type 2 (HSV-2) disease are limited.

In Europe, musculoskeletal disorders (MSDs) are the most common occupation-related diseases, and in the United States, MSDs occupy 5th place in causes of visits to medical facilities.

Osteoporosis is a bone disease characterized by low Bone Mineral Density (BMD) leading to a reduction in bone quality.

The lung tumor is a leading cause of death worldwide. This type of disease in which there is uncontrolled progression of abnormal cells in the lung, when untreated, can extend through the process of metastasis in nearby tissues and in different parts of the body [1].

Modern evidence-based cardiology still utilizes historical gem drugs in routine everyday practice. The analgesic and antiinflammatory attributes of the salicylate-rich willow bark extracts are mentioned in the 16th century Ebers papyrus [1].

The heart rhythms accompanied by systole and diastole can change the blood volume in the vessels under the skin surface, and further alter the light absorption/reflection of vessels.

T1D consists of selective autoimmune killing of pancreatic islet β-cells that physiologically accomplish the task of secreting insulin on a regulated manner, in order to maintain blood glucose levels within normal range (70-140 mg/dl), under any circumstances.

To compare the ability of different frailty indexes based on a standardized comprehensive geriatric assessment (FI-CGAs) for predicting adverse outcomes.Prospective cohort study. Geriatric wards of a general hospital.307 hospitalized patients ≥ 65 years.The FI-CGA-10D (potential health deficits in ten functional domains), the FI-CGA-10D+CM (aforementioned potential health deficits and co-morbidity burden) and the FI-CGA-MIHD (multiple, individual potential health deficits, including functional deficits, co-morbid diseases, amongst others) were assessed at baseline during the patients` hospital stay. The FI-CGAs were analyzed as categorical (according to a FI-CGA scoreand ≥ 0.25) and continuous variables. Patients were followed up over 6 months.The FI-CGA-10D, FI-CGA-10+CM and the FI-CGA-MIHD predicted 6-month mortality when expressed as categorical (area under the receiver operating characteristic curve (AUC): AUC = 0.611, AUC = 0.637, AUC = 0.616, all p0.050, respectively) or continuous variables (AUC = 0.769, AUC = 0.837, AUC = 0.834, all p0.001, respectively). AUC comparisons showed that all three FI-CGAs exhibited a comparable ability to predict 6-month mortality when the FI-CGAs were expressed as categorical variables (all p0.200) and the FI-CGA-10D+CM and the FI-CGA-MIHD showed a better ability to predict 6-month mortality than the FI-CGA-10D, when the FI-CGAs were expressed as continuous variables (p0.001 and p = 0.007, respectively). None of the FI-CGAs predicted any of the other outcomes, i.e., unplanned re-admission to hospital and a fall during follow-up, irrespective of whether the FI-CGAs were expressed as categorical or continuous variables (all p ≥ 0.050).The more complex FI-CGAs, i.e., the FI-CGA-10D+CM and the FI-CGA-MIHD, revealed better ability to predict 6 month mortality than the more simple FI-CGA, i.e., the FI-CGA-10D.

In clinical research as well as good clinical practice increasing importance is placed on standardized and evaluated procedures. They provide information which is important for the prognosis, determination of the need for interventions, determination of treatment goals and evaluation of treatment approaches and outcomes. Furthermore, they serve as justification of the reimbursement for presentation to official bodies. Until now no officially authorized German version of the performance-oriented mobility assessment (POMA) according to Tinetti was available.This article presents a methodically translated German version of the POMA that also includes so far partially unpublished instructions for the examiner and the examined person.The internationally recognized recommendations for the cross-cultural adaptation of health status measures served as the foundation of the translation process. By means of three translations from the original language into the target language a preliminary consensus version was developed, which was then translated back into the original language by two native speakers.With this new and for the first time authorized German translation of the POMA a version of this assessment is available that achieves unification and standardization in German speaking countries and guarantees an improved comparability with international studies.

There are few data regarding the accuracy of short frailty tools as predictors of mortality and other clinical outcomes of older patients admitted to a geriatric ward. We therefore analyzed the accuracy of Rockwood et al's Clinical Frailty Scale and an easy and quick to perform operationalization of Fried et al's frailty phenotype, as predictors of mortality and other clinical outcomes in our cohort of patients.Prospective analysis with a follow-up period of 6 months.307 patients who were 65 years of age or older were included in the study. The patients were assessed in terms of the two frailty measures during their stay in a geriatric ward.The Clinical Frailty Scale and the frailty phenotype were both suitable for differentiating between patients who died due to any cause from those who survived during follow-up (primary outcome) (area under the ROC curves (AUC) values 0.867 (95% CI 0.807-0.926), p0.001 and 0.754 (95% CI 0.688-0.821), p0.001, respectively). Regarding the secondary outcomes: 1. unplanned admission to hospital and 2. a fall during follow-up, the Clinical Frailty Scale discriminated or tended to discriminate between patients to whom these criteria applied and those to whom they did not (AUC=0.569 (95% CI 0.502-0.636), p=0.046 and AUC=0.574 (95% CI 0.501-0.647), p=0.071, respectively). The frailty phenotype did not show such a differentiation when applied to secondary outcomes (AUC=0.500 (95% CI 0.432-0.568), p=0.994 and AUC=0.518 (95% CI 0.439-0.598), p=0.658, respectively).Both short frailty instruments are suitable predictors of mortality in older patients who were admitted to a geriatric ward. The Clinical Frailty Scale, but not the frailty phenotype, predicted at least some of the secondary outcomes, i.e., the outcome unplanned admission to hospital during follow-up.