35 results on '"Kadayifcilar, Sibel"'
Search Results
2. Short-term effect of macular edema on the peripapillary retinal nerve fiber layer in patients with wet age-related macular degeneration and diabetic macular edema: A comparative study
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Dikmetas, Ozlem, Gungor, Gulce, Kapucu, Yasemin, Kocabeyoglu, Sibel, Kadayıfcılar, Sibel, Eldem, Bora, Karahan, Sevilay, and Cankaya, Ali Bülent
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- 2023
- Full Text
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3. Safety and efficacy of risdiplam in patients with type 1 spinal muscular atrophy (FIREFISH part 2): secondary analyses from an open-label trial
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Volpe, Joseph J, Posner, John, Kellner, Ulrich, Quinlivan, Rosaline, Gerber, Marianne, Khwaja, Omar, Scalco, Renata S, Seabrook, Timothy, Koch, Armin, Balikova, Irina, Joniau, Inge, Accou, Geraldine, Tahon, Valentine, Wittevrongel, Sylvia, De Vos, Elke, de Holanda Mendonça, Rodrigo, Matsui Jr, Ciro, Fornazieri Darcie, Ana Letícia, Machado, Cleide, Kiyoko Oyamada, Maria, Martini, Joyce, Polido, Graziela, Rodrigues Iannicelli, Juliana, Caires de Oliveira Achili Ferreira, Juliana, Hu, Chaoping, Zhu, Xiaomei, Qian, Chen, Shen, Li, Li, Hui, Shi, Yiyun, Zhou, Shuizhen, Xiao, Ying, Zhou, Zhenxuan, Wang, Sujuan, Sang, Tian, Wei, Cuijie, Dong, Hui, Cao, Yiwen, Wen, Jing, Li, Wenzhu, Qin, Lun, Barisic, Nina, Celovec, Ivan, Galiot Delic, Martina, Ivkic, Petra Kristina, Vukojevic, Nenad, Kern, Ivana, Najdanovic, Boris, Skugor, Marin, Tomas, Josipa, Boespflug-Tanguy, Odile, De Lucia, Silvana, Seferian, Andrea, Barreau, Emmanuel, Mnafek, Nabila, Peche, Helene, Grange, Allison, Trang Nguyen, Diem, Milascevic, Darko, Tachibana, Shotaro, Pagliano, Emanuela, Bianchi Marzoli, Stefania, Santarsiero, Diletta, Garcia Sierra, Myriam, Tremolada, Gemma, Arnoldi, Maria Teresa, Vigano, Marta, Dosi, Claudia, Zanin, Riccardo, Schembri, Veronica, Brolatti, Noemi, Rao, Giuseppe, Tassara, Elisa, Morando, Simone, Tacchetti, Paola, Pedemonte, Marina, Priolo, Enrico, Sposetti, Lorenza, Comi, Giacomo Pietro, Govoni, Alessandra, Osnaghi, Silvia Gabriella, Minorini, Valeria, Abbati, Francesca, Fassini, Federica, Foa, Michaela, Lopopolo, Amalia, Pane, Marika, Palermo, Concetta, Pera, Maria Carmela, Amorelli, Giulia Maria, Barresi, Costanza, D'Amico, Guglielmo, Orazi, Lorenzo, Coratti, Giorgia, Leone, Daniela, Laura, Antonaci, De Sanctis, Roberto, Berti, Beatrice, Kimura, Naoki, Takeshima, Yasuhiro, Shimomura, Hideki, Lee, Tomoko, Gomi, Fumi, Morimatsu, Takanobu, Furukawa, Toru, Stodolska-Koberda, Urszula, Waskowska, Agnieszka, Kolendo, Jagoda, Sobierajska-Rek, Agnieszka, Modrzejewska, Sandra, Lemska, Anna, Melnik, Evgenia, Artemyeva, Svetlana, Leppenen, Natalya, Yupatova, Nataliya, Monakhova, Anastasya, Papina, Yulia, Shidlovsckaia, Olga, Litvinova, Elena, Enzmann, Cornelia, Galiart, Elea, Gugleta, Konstantin, Wondrusch Haschke, Christine, Topaloglu, Haluk, Oncel, Ibrahim, Ertugrul, Nesibe Eroglu, Konuskan, Bahadir, Eldem, Bora, Kadayifçilar, Sibel, Alemdaroglu, Ipek, Sari, Seher, Bilgin, Neslihan, Karaduman, Aynur Ayse, Sarikaya, Fatma Gokcem Yildiz, Graham, Robert J, Ghosh, Partha, Casavant, David, Levine, Alexis, Titus, Rachael, Engelbrekt, Amanda, Ambrosio, Lucia, Fulton, Anne, Baglieri, Anna Maria, Dias, Courtney, Maczek, Elizabeth, Pasternak, Amy, Beres, Shannon, Duong, Tina, Gee, Richard, Young, Sally, Masson, Riccardo, Mazurkiewicz-Bełdzińska, Maria, Rose, Kristy, Servais, Laurent, Xiong, Hui, Zanoteli, Edmar, Baranello, Giovanni, Bruno, Claudio, Day, John W, Deconinck, Nicolas, Klein, Andrea, Mercuri, Eugenio, Vlodavets, Dmitry, Wang, Yi, Dodman, Angela, El-Khairi, Muna, Gorni, Ksenija, Jaber, Birgit, Kletzl, Heidemarie, Gaki, Eleni, Fontoura, Paulo, and Darras, Basil T
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- 2022
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4. Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo-controlled trial
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Volpe, Joseph J., Posner, John, Kellner, Ulrich, Quinlivan, Rosaline, Daron, Aurore, Delstanche, Stéphanie, Bruninx, Romain, Dal Farra, Fabian, Schneider, Olivier, Deconinck, Nicolas, Balikova, Irina, Delbeke, Patricia, Joniau, Inge, Tahon, Valentine, Wittevrongel, Sylvia, De Vos, Elke, Goemans, Nathalie, Casteels, Ingele, De Waele, Liesbeth, Cassiman, Catherine, Prové, Lies, Kinoo, David, Vancampenhout, Lisa, Van Den Hauwe, Marleen, Van Impe, Annelies, Prufer de Queiroz Campos Araujo, Alexandra, Chacon Pereira, Aline, Nardes, Flávia, Haefeli, Lorena, Rossetto, Julia, Ferreira Rebel, Marcos, Almeida Pereira, Jaqueline, Campbell, Craig, Sharan, Sapna, McDonald, Wendy, Scholtes, Cheryl, Mah, Jean, Sframeli, Maria, Chiu, Angela, Hagel, Jane, Oskoui, Maryam, Beneish, Raquel, Cariou-Palmer, Gaela, Pham, Connie, Toffoli, Daniela, Arpin, Stephanie, Turgeon Desilets, Sarah, Wang, Yi, Hu, Chaoping, Huan, Jianfeng, Qian, Chen, Shen, Li, Xiao, Ying, Zhou, Zhenxuan, Li, Hui, Wang, Sujuan, Xiong, Hui, Chang, Xingzhi, Dong, Hui, Liu, Ying, Sang, Tian, Wei, Cuijie, Wen, Jing, Cao, Yiwen, Ly, Xingyao, Zhao, Jingjing, Li, Wenzhu, Qin, Lun, Barisic, Nina, Galiot Delic, Martina, Ivkic, Petra Kristina, Vukojevic, Nenad, Kern, Ivana, Najdanovic, Boris, Skugor, Marin, Servais, Laurent, Boespflug-Tanguy, Odile, Gidaro, Teresa, Seferian, Andreea, De Lucia, Silvana, Barreau, Emmanuel, Mnafek, Nabila, Momtchilova, Marta Milkova, Peche, Helene, Valherie, Carole, Grange, Allison, Lilien, Charlotte, Milascevic, Darko, Tachibana, Shotaro, Ravelli, Claudia, Cardas, Ruxandra, Taytard, Jessica, Aubertin, Guillaume, Vanden Brande, Laure, Davion, Jean-Baptiste, Coopman, Stephanie, Bouacha, Ikram, Debruyne, Philippe, Defoort, Sabine, Derlyn, Gilles, Leroy, Florian, Danjoux, Loïc, Guilbaud, Julie, Desguerre, Isabelle, Barnérias, Christine, Semeraro, Michaela, Bremond-Gignac, Dominique, Bruere, Lenaic, Rateaux, Maxence, Deladrière, Élodie, Germa, Virginie, Pereon, Yann, Mercie, Sandra, Billaud, Fanny, Le Goff, Lucie, Letellier, Guy, Vuillerot, Carole, Portefaix, Aurélie, De-Montferrand, Camille, Le-Goff, Laure, Fontaine, Stephanie, Saidi, Manel, Bouzid, Nabil, Barriere, Aurélie, Tinat, Marie, Kirschner, Janbernd, Dreesbach, Michelle, Lagréze, Wolf, Michaelis, Bettina, Molnar, Fanni, Seger, Dorina, Vogt, Sibylle, Bertini, Enrico, D'Amico, Adele, Petroni, Sergio, Bonetti, Anna Maria, Carlesi, Adelina, Mizzoni, Irene, Bruno, Claudio, Priolo, Enrico, Rao, Giuseppe, Morando, Simone, Tacchetti, Paola, Zuffi, Ambra, Comi, Giacomo Pietro, Brusa, Roberta, Corti, Stefania, Daniele, Velardo, Govoni, Alessandra, Magri, Francesca, Minorini, Valeria, Osnaghi, Silvia Gabriella, Abbati, Francesca, Fassini, Federica, Foa, Michaela, Lopopolo, Amaqlia, Meneri, Megi, Zoppas, Francesca, Parente, Valeria, Baranello, Giovanni, Masson, Riccardo, Bianchi Marzoli, Stefania, Santarsiero, Diletta, Garcia Sierra, Myriam, Tremolada, Gemma, Arnoldi, Maria Teresa, Vigano, Marta, Zanin, Riccardo, Mercuri, Eugenio, Antonaci, Laura, de Sanctis, Roberto, Pane, Marika, Pera, Maria Carmela, Amorelli, Giulia Maria, Barresi, Costanza, D'Amico, Gugliemo, Orazi, Lorenzo, Coratti, Giorgia, Haginoya, Kazuhiro, Kato, Atsuko, Morishita, Yuko, Kira, Ryutaro, Akiyama, Kiyomu, Goto, Miwako, Mori, Yujiro, Okamoto, Misato, Tsutsui, Saki, Takatsuji, Yuta, Tanaka, Aya, Komaki, Hirofumi, Omori, Miina, Suzuki, Ippei, Takeuchi, Mizuki, Todoroki, Daisuke, Watanabe, Seji, Matsubayashi, Tomoko, Inakazu, Emi, Nagura, Hiroe, Suzuki, Akira, Usui, Manami, Ishikawa, Nobutsune, Harada, Yousuke, Fudeyasu, Kenishi, Hirata, Kazuhiko, Michiue, Kana, Ueda, Kazuyuki, Saito, Kayoko, Fujitani, Junko, Arakawa, Reiko, Takano, Kozue, Yashiro, Shigeko, Seki, Maiko, Sano, Nozomi, Fukuyama, Koji, Matsumoto, Yuki, Miyazaki, Hirofumi, Shibata, Minoru, Kobayashi, Kyoko, Nakamura, Yukie, Takeshima, Yasuhiro, Kuma, Moe, Kostera-Pruszczyk, Anna, Fraczek, Anna, Jedrzejowska, Maria, Lusakowska, Anna, Czeszyk-Piotrowicz, Agnieszka, Hautz, Wojciech, Rakusiewicz, Klaudia, Burlewicz, Malgorzata, Gierlak-Wojcicka, Zuzanna, Kepa, Malwina, Sikorski, Adam, Sobieraj, Marcin, Mazurkiewicz-Beldzinska, Maria, Lemska, Anna, Modrzejewska, Sandra, Koberda, Mateusz, Stodolska-Koberda, Urszula, Waskowska, Agnieszka, Kolendo, Jagoda, Sobierajska-Rek, Agnieszka, Steinborn, Barbara, Dalz, Magdalena, Grabowska, Julia, Hajduk, Wojciech, Janasiewicz-Karachitos, Justyna, Klimas, Monika, Stopa, Marcin, Gajewska, Ewa, Pusz, Beata, Vlodavets, Dmitry, Melnik, Evgenia, Leppenen, Natalya, Yupatova, Nataliya, Monakhova, Anastasya, Papina, Yulia, Shidlovsckaia, Olga, Milic Rasic, Vedrana, Brankovic, Vesna, Kosac, Ana, Djokic, Olivera, Jakšic, Vesna, Pepic, Ana, Martinovic, Jelena, Munell Casadesus, Francina, Tizzano, Eduardo, Martín Begué, Nieves, Wolley Dod, Charlotte, Subira, Olaia, Planas Pascual, Bernat, Toro Tamargo, Esther, Madruga Garrido, Marcos, Medina Romero, José David, Salinas, Marta Peña, Nascimento Osorio, Andrés, Díaz Cortés, Ana, Jiménez Gañan, Enrique, Suh, Simone Dowon, Medina Cantillo, Julita, Moya, Obdulia, Padros, Nuria, Urraca, Sandra Roca, Valdivia, Hugo Gonzalez, Pascual Pascual, Samuel, de Manuel, Sofía, Martin, Susana Noval, Burnham, Paul, Espinosa, Sandra, Moreno, Mercedes Martinez, Topaloglu, Haluk, Oncel, Ibrahim, Eroglu Ertugru, Nesibe, Konuskan, Bahadir, Eldem, Bora, Kadayifçilar, Sibel, Alemdaroglu, Ipek, Karaduman, Aynur Ayse, Yilmaz, Oznur Tunca, Bilgin, Neslihan, Sari, Seher, Chiriboga, Claudia, Lee, John J., Rome-Martin, Donnielle, Day, John W., Beres, Shannon, Duong, Tina, Gee, Richard, Dunaway Young, Sally, Fuerst-Recktenwald, Sabine, Marquet, Anne, Muelhardt, Nicoletta, Trundell, Dylan, Mazzone, Elena S, Nascimento, Andres, Gerber, Marianne, Gorni, Ksenija, Khwaja, Omar, Kletzl, Heidemarie, Scalco, Renata S, Staunton, Hannah, Yeung, Wai Yin, Martin, Carmen, Fontoura, Paulo, and Day, John W
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- 2022
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5. Prepapillary vascular loop-a new classification
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Mansour, Ahmad M., Kozak, Igor, Saatci, Ali Osman, Ascaso, Francisco J., Broc, Laura, Battaglia, Maurizio, Olivier, Nuria, Gili, Pablo, Chhablani, Jay, Hedges, Thomas R., Honrubia, Ana, Gutierrez, Laura, Panozzo, Giacomo, Català, Jaume, Díaz, Jesús, Carreras, Elisa, Kadayifcilar, Sibel, Al Kahtani, Eman S., Uwaydat, Sami H., Lima, Luiz H., Mansour, Hana A., Khan, Hashim Ali, Aaberg, Jr, Thomas M., Bovino, Jerald A., and Hunyor, Alex P.
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- 2021
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6. Anatomic Reattachment Surgery, for Retinal Detachment
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Kadayıfçılar, Sibel, Eldem, Bora, Schmidt-Erfurth, Ursula, editor, and Kohnen, Thomas, editor
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- 2018
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7. Successful management of rhabdomyolysis with triheptanoin in a child with severe long-chain 3-hydroxyacyl-coenzyme A dehydrogenase (LCHAD) deficiency
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Kahraman, Ayca Burcu, primary, Yildiz, Yılmaz, additional, Gokmen-Ozel, Hulya, additional, Kadayifcilar, Sibel, additional, and Sivri, Serap, additional
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- 2023
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8. Prevalence of cerebrotendinous xanthomatosis in cases with idiopathic bilateral juvenile cataract in ophthalmology clinics in Turkey
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Atilla, Huban, Coskun, Turgay, Elibol, Bulent, Kadayifcilar, Sibel, and Altinel, Serdar
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- 2021
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9. INTRAVITREAL DEXAMETHASONE (OZURDEX) IMPLANT FOR RADIATION MACULOPATHY SECONDARY TO STEREOTACTIC RADIOTHERAPY FOR POSTERIOR UVEAL MELANOMA
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Koc, Irem, Kadayifcilar, Sibel, Kiratli, Hayyam, and Eldem, Bora
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- 2019
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10. Report of 2 pediatric cases with atypical Cogan's syndrome and a systematic review
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Kasap Cuceoglu, Muserref, primary, Basaran, Ozge, additional, Batu, Ezgi Deniz, additional, Kaya Akca, Ummusen, additional, Atalay, Erdal, additional, Sener, Seher, additional, Balik, Zeynep, additional, Bayindir, Yagmur, additional, Aliyev, Emil, additional, Gocmen, Rahsan, additional, Kadayifcilar, Sibel, additional, Akyol, Umut, additional, Bilginer, Yelda, additional, and Ozen, Seza, additional
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- 2022
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11. Multimodal Imaging of Severe Oxalate Retinopathy in a 20-Month-Old Boy
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Aygün, Figen Bezci, primary, Kadayifcilar, Sibel, additional, Lotfi Sadigh, Sepide, additional, Ozaltin, Fatih, additional, and Eldem, Bora, additional
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- 2022
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12. Report of 2 pediatric cases with atypical Cogan's syndrome and a systematic review.
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Kasap Cuceoglu, Muserref, Basaran, Ozge, Batu, Ezgi Deniz, Kaya Akca, Ummusen, Atalay, Erdal, Sener, Seher, Balik, Zeynep, Bayindir, Yagmur, Aliyev, Emil, Gocmen, Rahsan, Kadayifcilar, Sibel, Akyol, Umut, Bilginer, Yelda, and Ozen, Seza
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SENSORINEURAL hearing loss ,CHILD patients ,HEARING disorders ,COCHLEAR implants ,SYNDROMES ,IRIDOCYCLITIS - Abstract
Cogan's syndrome (CS) is a rare inflammatory disease characterized by interstitial keratitis or uveitis, vestibular impairment, and progressive hearing loss, commonly bilateral. Although glucocorticoids are fundamental treatment options, in most cases, hearing loss gradually worsens. Herein we report 2 pediatric cases of CS who were treated with corticosteroids and methotrexate. One patient had a cochlear implant, and the hearing of the other patient improved with treatment. Also, a systematic literature review was conducted for articles including pediatric CS patients. In the literature, 34 articles describing 44 pediatric patients with CS were identified. Sudden hearing loss (95.3%) and ocular symptoms (92.5%) were the most common manifestations in these patients. Also, aortic involvement was present in 19.5% of patients in the literature. Otorhinolaryngologists, ophthalmologists, and pediatricians should collaborate to diagnose and manage CS to prevent progressive hearing loss and eye involvement. [ABSTRACT FROM AUTHOR]
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- 2023
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13. Familial Mediterranean fever associated frosted branch angiitis, retinal vasculitis and vascular occlusion
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Mansour, Hana A., primary, Ozdal, Pinar Ç, additional, Kadayifcilar, Sibel, additional, Tugal-Tutkun, Ilknur, additional, Eser-Ozturk, Hilal, additional, Yalçındağ, F. Nilüfer, additional, Petrushkin, Harry, additional, Chan, Errol W., additional, Belfaiza, Soukaina, additional, Karadag, Remzi, additional, Güngör, Sirel Gür, additional, Parodi, Maurizio Battaglia, additional, and Mansour, Ahmad M., additional
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- 2021
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14. Clinical characteristics of full thickness macular holes that closed without surgery.
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Uwaydat, Sami H., Mansour, Ahmad, Ascaso, Francisco J., Battaglia Parodi, Maurizio, Foster, Robert, Smiddy, William E., Schwartz, Stephen G., Charbaji, Abdulrazzak, Belotto, Silvana, Jürgens, Ignasi, Mateo, Javier, Ellabban, Abdallah A., Lihteh Wu, Figueroa, Marta, Olivier Pascual, Nuria, Lima, Luiz H., Alsakran, Wael A., Kadayifcilar, Sibel Caliskan, Sinawat, Suthasinee, and Assi, Alexandre
- Abstract
Purpose To ascertain the anatomic factors that help achieve non-surgical sealing in full thickness macular hole (FTMH). Methods Retrospective collaborative study of FTMH that closed without surgical intervention. Results A total of 78 patients (mean age 57.9 years) included 18 patients with blunt ocular trauma, 18 patients that received topical or intravitreal therapies and 42 patients with idiopathic FTMH. Mean±SD of the initial corrected visual acuity (VA) in logMAR improved from 0.65±0.54 to 0.34±0.45 (p<0.001) at a mean follow-up of 33.8±37.1 months. FTMH reopened in seven eyes (9.0%) after a mean of 8.6 months. Vitreomacular traction was noted in 12 eyes (15.8%), perifoveal posterior vitreous detachment in 42 (53.8%), foveal epiretinal membrane in 10 (12.8%), cystoid macular oedema (CME) in 49 (62.8%) and subretinal fluid (SRF) in 20 (25.6%). By multivariate analysis, initial VA correlated to the height (p<0.001) and narrowest diameter of the hole (p<0.001) while final VA correlated to the basal diameter (p<0.001). Time for closure of FTMH (median 2.8 months) correlated to the narrowest diameter (p<0.001) and the presence of SRF (p=0.001). Mean time for closure (in months) was 1.6 for eyes with trauma, 4.3 for eyes without trauma but with therapy for CME, 4.4 for eyes without trauma and without therapy in less than 200 µm in size and 24.7 for more than 200 µm. Conclusion Our data suggest an observation period in new onset FTMH for non-surgical closure, in the setting of trauma, treatment of CME and size <200 µm. [ABSTRACT FROM AUTHOR]
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- 2022
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15. A randomized trial to compare the safety and efficacy of two ranibizumab dosing regimens in a Turkish cohort of patients with choroidal neovascularization secondary to AMD
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Eldem, Bora M., Muftuoglu, Gulipek, Topbaş, Seyhan, Çakir, Mehmet, Kadayifcilar, Sibel, Özmert, Emin, Bahçecioğlu, Halil, Sahin, Feride, and Sevgi, Serhan
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- 2015
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16. Ranibizumab therapy for predominantly hemorrhagic neovascular age-related macular degeneration.
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Dikmetas, Ozlem, Kadayifcilar, Sibel, Eldem, Bora, and Feyzullayeva, Ulkar
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RANIBIZUMAB ,MACULAR degeneration ,OPTICAL coherence tomography ,FLUORESCENCE angiography ,AGE factors in disease - Abstract
OBJECTIVE: Predominantly hemorrhage represents one of the possible manifestations of choroidal neovascularisation (CNV) in eyes with age-related macular degeneration (AMD). The purpose of this study is to evaluate the effecte of ranibizumab treatment in patients with predominantly hemorrhagic CNV secondary to AMD. METHODS: Twenty-five patients with predominantly hemorrhagic choroidal neovascularization due to AMD with at least three ranibizumab injections and followed up for at least 12 months were included in the study. The months of follow-up were recorded (baseline, 3rd, 6th, and 12th months). The change in central macular thickness (CMT) on optical coherence tomography, visual acuity (VA) in ETDRS letters, and lesion size on fundus fluorescein angiography were evaluated. RESULTS: The mean age of the patients was 68.1±5.7 (range: 63-82) years, the mean follow-up was 19.9±14.5 (range: 12-67) months, and the mean number of injections was 4.0±1.4 (range: 3-15). The initial VA was 39.3±17.9 (range: 1-65) letters, CMT was 272.7±104 (range: 164-587) µm, and the initial lesion width was 11.4±10.5 (range: 1.3-45.7) mm2. The VA was 41.4±20.1 (range: 5-75) and 36.9±21.8 (range: 4-80) letters (p=0.150), CMT was 270.7±110 (range: 159-570) and 230.4±108 (range: 109-667) µm (p=0.009) and the lesion width was 10.9±11.5 (range: 1.1-39.7) and 10.4±11.6 (range: 1.2-44.3) mm2 at 6th and 12th month, respectively. No factor was found to be associated with final CMT. CONCLUSION: Although the final visual outcome is limited by the progression of the disease, hemorrhagic lesions treated with ranibizumab have stable anatomical outcome. [ABSTRACT FROM AUTHOR]
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- 2022
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17. An Algorithm for the Diagnosis of Behçet Disease Uveitis in Adults.
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Tugal-Tutkun, Ilknur, Onal, Sumru, Stanford, Miles, Akman, Mehmet, Twisk, Jos W.R., Boers, Maarten, Oray, Merih, Özdal, P., Kadayifcilar, Sibel, Amer, Radgonde, Rathinam, Sivakumar R., Vedhanayaki, Rajesh, Khairallah, Moncef, Akova, Yonca, Yalcindag, F., Kardes, Esra, Basarir, Berna, Altan, Çigdem, Özyazgan, Yilmaz, and Gül, Ahmet
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IRIDOCYCLITIS ,BEHCET'S disease ,CART algorithms ,UVEITIS ,DIAGNOSIS ,ADULTS - Abstract
Purpose: To develop an algorithm for the diagnosis of Behçet's disease (BD) uveitis based on ocular findings. Methods: Following an initial survey among uveitis experts, we collected multi-center retrospective data on 211 patients with BD uveitis and 207 patients with other uveitides, and identified ocular findings with a high diagnostic odds ratio (DOR). Subsequently, we collected multi-center prospective data on 127 patients with BD uveitis and 322 controls and developed a diagnostic algorithm using Classification and Regression Tree (CART) analysis and expert opinion. Results: We identified 10 items with DOR >5. The items that provided the highest accuracy in CART analysis included superficial retinal infiltrate, signs of occlusive retinal vasculitis, and diffuse retinal capillary leakage as well as the absence of granulomatous anterior uveitis or choroiditis in patients with vitritis. Conclusion: This study provides a diagnostic tree for BD uveitis that needs to be validated in future studies. [ABSTRACT FROM AUTHOR]
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- 2021
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18. An Algorithm for the Diagnosis of Behçet Disease Uveitis in Adults
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Tugal-Tutkun, Ilknur, primary, Onal, Sumru, additional, Stanford, Miles, additional, Akman, Mehmet, additional, Twisk, Jos W.R., additional, Boers, Maarten, additional, Oray, Merih, additional, Özdal, P., additional, Kadayifcilar, Sibel, additional, Amer, Radgonde, additional, Rathinam, Sivakumar R., additional, Vedhanayaki, Rajesh, additional, Khairallah, Moncef, additional, Akova, Yonca, additional, Yalcindag, F., additional, Kardes, Esra, additional, Basarir, Berna, additional, Altan, Çigdem, additional, Özyazgan, Yilmaz, additional, and Gül, Ahmet, additional
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- 2020
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19. Prepapillary vascular loop-a new classification
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Mansour, Ahmad M., primary, Kozak, Igor, additional, Saatci, Ali Osman, additional, Ascaso, Francisco J., additional, Broc, Laura, additional, Battaglia, Maurizio, additional, Olivier, Nuria, additional, Gili, Pablo, additional, Chhablani, Jay, additional, Hedges, Thomas R., additional, Honrubia, Ana, additional, Gutierrez, Laura, additional, Panozzo, Giacomo, additional, Català, Jaume, additional, Díaz, Jesús, additional, Carreras, Elisa, additional, Kadayifcilar, Sibel, additional, Al Kahtani, Eman S., additional, Uwaydat, Sami H., additional, Lima, Luiz H., additional, Mansour, Hana A., additional, Khan, Hashim Ali, additional, Aaberg, Thomas M., additional, Bovino, Jerald A., additional, and Hunyor, Alex P., additional
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- 2020
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20. Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units
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Bas, Ahmet Yagmur, Demirel, Nihal, Koc, Esin, Isik, Dilek Ulubas, Hirfanoglu, Ibrahim Murat, Tunc, Turan, Sari, Fatma Nur, Karatekin, Guner, Koklu, Esad, Altunhan, Huseyin, Turgut, Hatice, Narter, Fatma, Tarakci, Nuriye, Tekgunduz, Kadir Serafettin, Ozkiraz, Servet, Aydemir, Cumhur, Ozdemir, Ahmet, Cetinkaya, Bilin, Kazanci, Ebru, Tastekin, Ayhan, Calkavur, Sebnem, Ozyurt, Banu Mutlu, Demirelli, Yasar, Asker, Huseyin Selim, Mutlu, Birgul, Uygur, Ozgun, Ozkan, Hilal, Armangil, Didem, Ozlu, Ferda, Mert, Mustafa Kurthan, Ergin, Hacer, Ozcan, Beyza, Bas, Evrim Kiray, Okulu, Emel, Acunas, Betul, Celik, Ulker, Uslu, Sait Ilker, Mutlu, Mehmet, Demir, Nihat, Eroglu, Funda, Gokmen, Zeynel, Beken, Serdar, Bayraktar, Bilge Tanyeri, Hakan, Nilay, Kucuktasci, Kazim, Orman, Aysen, Comert, Serdar, Ertugrul, Sabahattin, Ustun, Nuran, Sahin, Ozlem, Terek, Demet, Kale, Yusuf, Konak, Murat, Yurttutan, Sadik, Aydemir, Ozge, Zenciroglu, Aysegul, Sarici, Dilek, Guzoglu, Nilufer, Hamilcikan, Sahin, Gursoy, Tugba, Tuzun, Funda, Ors, Rahmi, Arslan, Selda, Akdag, Arzu, Memisoglu, Asli, Yasa, Beril, Hekimoglu, Berna, Turan, Ozden, Aylanc, Hakan, Takci, Sahin, Celik, Tolga, Sahin, Suzan, Kilic, Ilknur, Kara, Caner, Tunay, Zuhal Ozen, Celik, Gokhan, Gozen, Ibrahim, Satirtav, Gunhal, Polat, Nihat, Oral, Ayse Yesim, Tokgoz, Mine, Keles, Sadullah, Bilgin, Burak, Ugurbas, Silay Canturk, Karaca, Cagatay, Keskek, Nedime Sahinoglu, Ekinci, Dilbade Yildiz, Balci, Ozlem, Altan, Emir Volkan, Bakbak, Sevda, Ceylan, Nihan Aksu, Kimyon, Sabit, Alyamac, Gunay, Ture, Gamze, Yildiz, Meral, Calis, Feyza, Sizmaz, Selcuk, Sukgen, Emine, Cetin, Ebru Nevin, Ozcimen, Muammer, Demir, Semra Tiryaki, Atila, Huban, Ozal, Altan, Tufaner, Gokhan, Yucel, Ozlem Eski, Kola, Mehmet, Seven, Erbil, Ozdek, Sengul, Durukan, Ali Hakan, Kal, Ali, Celebi, Ali Riza Cenk, Koytak, Ibrahim Arif, Alacamli, Goksu, Esme, Arif, Catak, Onur, Perente, Irfan, Sahin, Alparslan, Akcakaya, Aylin Ardagil, Kiray, Gulunay, Nalcaci, Serhat, Aksoy, Umit, Bakbak, Berker, Comez, Aysegul, Gursoy, Huseyin, Kabatas, Emrah Utku, Petricli, Ikbal Seza, Yumusak, Mehmet Erhan, Kirgiz, Ahmet, Uludag, Gunay, Yaman, Aylin, Dadaci, Zeynep, Karatas, Ali, Celiker, Hande, Cebeci, Zafer, Esenulku, Mahmut Cenap, Akkoyun, Imren, Ersan, Ismail, Demir, Selim, Kadayifcilar, Sibel, Unsal, Ayse Ipek Akyuz, Hocaoglu, Mumin, Grp, T. R.-R.O.P. Study, Ege Üniversitesi, Zonguldak Bülent Ecevit Üniversitesi, Çukurova Üniversitesi, Çocuk Sağlığı ve Hastalıkları, KOYTAK, İBRAHİM ARİF, Uludağ, Günay (ORCID & YÖK ID 175586), Gürsoy, Tuğba (ORCID 0000-0002-6084-4067 & YÖK ID 214691), Baş, Ahmet Yağmur, Demirel, Nihal, Koç, Esin, Işık, Dilek Ulubaş, Hirfanoğlu, İbrahim Murat, Tunç, Turan, Sarı, Fatma Nur, Karatekin, Güner, Köklü, Esad, Altunhan, Hüseyin, Turgut, Hatice, Narter, Fatma, Tarakçı, Nuriye, Tekgündüz, Kadir Şerafettin, Özkiraz, Servet, Aydemir, Cumhur, Özdemir, Ahmet, Çetinkaya, Bilin, Kazancı, Ebru, Taştekin, Ayhan, Calkavur, Şebnem, Özyurt, Banu Mutlu, Demirelli, Yaşar, Asker, Hüseyin Selim, Mutlu, Birgul, Uygur, Özgün, Özkan, Hilal, Armangil, Didem, Özlü, Ferda, Mert, Mustafa Kurthan, Ergin, Hacer, Özcan, Beyza, Baş, Evrim Kıray, Okulu, Emel, Acunas, Betül, Çelik, Ülker, Uslu, Sait İlker, Mutlu, Mehmet, Demir, Nihat, Eroğlu, Funda, Gökmen, Zeynel, Beken, Serdar, Bayraktar, Bilge Tanyeri, Hakan, Nilay, Küçüktaşçı, Kazım, Orman, Ayşen, Cömert, Serdar, Ertuğrul, Sabahattin, Üstün, Nuran, Şahin, Özlem, Terek, Demet, Kale, Yusuf, Konak, Murat, Yurttutan, Sadık, Aydemir, Özge, Zenciroğlu, Aysegül, Sarıcı, Dilek, Güzoğlu, Nilüfer, Hamilçıkan, Şahin, Tüzün, Funda, Örs, Rahmi, Arslan, Selda, Akdağ, Arzu, Memişoğlu, Aslı, Yasa, Beril, Hekimoğlu, Berna, Turan, Özden, Aylanc, Hakan, Takçı, Şahin, Çelik, Tolga, Şahin, Suzan, Kılıç, İlknur, Kara, Caner, Tunay, Zuhal Özen, Çelik, Gökhan, Gözen, İbrahim, Satırtav, Günhal, Polat, Nihat, Oral, Ayşe Yeşim, Tokgöz, Mine, Keleş, Sadullah, Bilgin, Burak, Uğurbaş, Silay Cantürk, Karaca, Çağatay, Keşkek, Nedime Şahinoğlu, Ekinci, Dilbade Yıldız, Balcı, Özlem, Altan, Emir Volkan, Bakbak, Sevda, Ceylan, Nihan Aksu, Kimyon, Sabit, Alyamaç, Günay, Türe, Gamze, Yıldız, Meral, Çalış, Feyza, Sızmaz, Selçuk, Sukgen, Emine, Çetin, Ebru Nevin, Özçimen, Muammer, Demir, Semra Tiryaki, Atila, Huban, Özal, Altan, Tufaner, Gökhan, Yücel, Özlem Eski, Kola, Mehmet, Seven, Erbil, Özdek, Şengül, Durukan, Ali Hakan, Kal, Ali, Çelebi, Ali Riza Cenk, Koytak, İbrahim Arif, Alaçamlı, Göksu, Esme, Arif, Çatak, Onur, Perente, İrfan, Şahin, Alparslan, Akçakaya, Aylin Ardagil, Kıray, Gülünay, Nalçacı, Serhat, Aksoy, Ümit, Bakbak, Berker, Çömez, Ayşegül, Gürsoy, Hüseyin, Kabataş, Emrah Utku, Petricli, İkbal Seza, Yumuşak, Mehmet Erhan, Kırgız, Ahmet, Yaman, Aylin, Dadacı, Zeynep, Karataş, Ali, Çeliker, Hande, Cebeci, Zafer, Esenülkü, Mahmut Cenap, Akkoyun, İmren, Ersan, İsmail, Demir, Selim, Kadayıfçılar, Sibel, Ünsal, Ayşe İpek Akyüz, Hocaoğlu, Mümin, School of Medicine, Department of Internal Medicine, MÜ, Kırıkkale Üniversitesi, Selçuk Üniversitesi, Bas, Ahmet Yagmur, Koc, Esin, Isik, Dilek Ulubas, Hirfanoglu, Ibrahim Murat, Tunc, Turan, Sari, Fatma Nur, Karatekin, Guner, Koklu, Esad, Altunhan, Huseyin, Tarakci, Nuriye, Tekgunduz, Kadir Serafettin, Ozkiraz, Servet, Ozdemir, Ahmet, Cetinkaya, Bilin, Kazanci, Ebru, Tastekin, Ayhan, Calkavur, Sebnem, Ozyurt, Banu Mutlu, Demirelli, Yasar, Asker, Huseyin Selim, Uygur, Ozgun, Ozkan, Hilal, Ozlu, Ferda, Ozcan, Beyza, Bas, Evrim Kiray, Acunas, Betul, Celik, Ulker, Uslu, Sait Ilker, Eroglu, Funda, Gokmen, Zeynel, Kucuktasci, Kazim, Orman, Aysen, Comert, Serdar, Ertugrul, Sabahattin, Ustun, Nuran, Sahin, Ozlem, Yurttutan, Sadik, Aydemir, Ozge, Zenciroglu, Aysegul, Sarici, Dilek, Guzoglu, Nilufer, Hamilcikan, Sahin, Gursoy, Tugba, Tuzun, Funda, Ors, Rahmi, Akdag, Arzu, Memisoglu, Asli, Hekimoglu, Berna, Turan, Ozden, Takci, Sahin, Celik, Tolga, Sahin, Suzan, Kilic, Ilknur, Tunay, Zuhal Ozen, Celik, Gokhan, Gozen, Ibrahim, Satirtav, Gunhal, Oral, Ayse Yesim, Tokgoz, Mine, Keles, Sadullah, Ugurbas, Silay Canturk, Karaca, Cagatay, Keskek, Nedime Sahinoglu, Ekinci, Dilbade Yildiz, Balci, Ozlem, Alyamac, Gunay, Ture, Gamze, Yildiz, Meral, Calis, Feyza, Sizmaz, Selcuk, Cetin, Ebru Nevin, Ozcimen, Muammer, Ozal, Altan, Tufaner, Gokhan, Yucel, Ozlem Eski, Ozdek, Sengul, Celebi, Ali Riza Cenk, Koytak, Ibrahim Arif, Alacamli, Goksu, Catak, Onur, Perente, Irfan, Sahin, Alparslan, Akcakaya, Aylin Ardagil, Kiray, Gulunay, Nalcaci, Serhat, Aksoy, Umit, Comez, Aysegul, Gursoy, Huseyin, Kabatas, Emrah Utku, Petricli, Ikbal Seza, Yumusak, Mehmet Erhan, Kirgiz, Ahmet, Uludag, Gunay, Dadaci, Zeynep, Karatas, Ali, Celiker, Hande, Esenulku, Mahmut Cenap, Akkoyun, Imren, Ersan, Ismail, Kadayifcilar, Sibel, Unsal, Ayse Ipek Akyuz, Hocaoglu, Mumin, OMÜ, Tıp Fakültesi, and Acibadem University Dspace
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Male ,BLOOD-TRANSFUSION ,Pediatrics ,Turkey ,INFANTS ,Logistic regression ,0302 clinical medicine ,Risk Factors ,FOR-GESTATIONAL-AGE ,Prevalence ,Birth Weight ,Infant, Very Low Birth Weight ,Prospective Studies ,Prospective cohort study ,[Anahtar Kelime Yok] ,Neovascularisation ,Incidence ,Incidence (epidemiology) ,Gestational age ,Retinopathy of prematurity ,Clinical Science ,Sensory Systems ,Female ,Infant, Premature ,Child health (paediatrics) ,Retina ,Treatment medical ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Birth weight ,Gestational Age ,Sepsis ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,Neonatal Screening ,Intensive Care Units, Neonatal ,030225 pediatrics ,Intensive care ,medicine ,Humans ,Retinopathy of Prematurity ,business.industry ,Child Health (paediatrics) ,Infant, Newborn ,[No Keywords] ,Infant ,medicine.disease ,eye diseases ,Ophthalmology ,For-Gestational-Age ,TR-ROP Study ,030221 ophthalmology & optometry ,Treatment Medical ,Blood-Transfusion ,WEIGHT ,Weight ,Infants ,Severity of Retinopathy ,business ,Medicine - Abstract
Background To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition., Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)=1500 g or gestational age (GA) 1500 g or GA> 32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses., Results The TR-ROP study included 6115 infants: 4964 (81%) with a GA 32 weeks. Overall, 27% had any stage of ROP and 6.7% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW=1500 g. Of all infants, 414 needed treatment and 395 (95.4%) of the treated infants had a BW, Conclusions Screening of infants with a GA
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- 2018
21. Efficacy and Safety of Sarilumab for the Treatment of Posterior Segment Noninfectious Uveitis (SARIL-NIU)
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Heissigerová, Jarmila, primary, Callanan, David, additional, de Smet, Marc D., additional, Srivastava, Sunil K., additional, Karkanová, Michala, additional, Garcia-Garcia, Olga, additional, Kadayifcilar, Sibel, additional, Ozyazgan, Yilmaz, additional, Vitti, Robert, additional, Erickson, Kristine, additional, Athanikar, Aditya, additional, Chu, Karen, additional, Saroj, Namrata, additional, Sundaram, Preethi A., additional, Varona, Rafael, additional, Corp-dit-Genti, Valerie, additional, Buggage, Ronald, additional, Cheng, Yenchieh, additional, Soo, Yuhwen, additional, and Nguyen, Quan Dong, additional
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- 2019
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22. Recovery course of persistent posterior subretinal fluid after successful repair of rhegmatogenous retinal detachment
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Mansour, Ahmad M, López-Guajardo, Lorenzo, Belotto, Silvana, Lima, Luiz H, Charbaji, Abdul Razzak, Schwartz, Stephen G, Wu, Lihteh, Smiddy, William E, Ascaso, Javier, Jürgens, Ignasi, Foster, Robert E, Elnahry, Ayman G, Sinawat, Suthasinee, Pinilla, Isabel, Pérez-Salvador García, Eduardo, Suarez Leoz, Marta, Olivier Pascual, Nuria, Zago Ribeiro, Lucas, Arroyo Castillo, Rosa, Navea, Amparo, Kadayifcilar, Sibel, Ellabban, Abdallah A, Rey, Amanda, Mansour, Hana A, Tripathy, Koushik, Kozak, Igor, Uwaydat, Sami H, Valero, María Sacramento, Cobo-Soriano, Rosario, Díaz-Barreda, María Dolores, Monje Fernández, Laura, González del Valle, Fernando, López Liroz, Irene, Vazquez Cruchaga, Erika, Fonollosa, Alex, Esteban Floria, Olivia, Relimpio Lopez, Maria Isabel, Shah, Gaurav, Wingelaar, Maxwell J, Ravani, Raghav, Donate-López, Juan, Rubio Velázquez, Elena, and Parodi, Maurizio
- Abstract
Purpose To investigate best corrected visual acuity (BCVA), subretinal fluid (SRF) absorption time or ellipsoid zone (EZ) restoration time and various variables in patients with persistent SRF after successful primary repair of rhegmatogenous retinal detachment (RRD).Methods This retrospective multicenter study allowed independent analysis of the healing pattern by two observers based on composite of serial cross-sectional macular optical coherence tomography (OCT) scans. Univariate and multivariate analyses were implemented.Results One hundred and three cases had persistent SRF after pars plana vitrectomy, scleral buckling, or pneumatic retinopexy. By univariate analysis, SRF resolution time correlated positively with the number of retinal breaks (p< 0.001) and with increased myopia (p= 0.011). Using multivariate analysis, final BCVA (log MAR) correlated positively with age, duration of RRD, initial BCVA (OR = 3.28; [95%CI = 1.44–7.47]; p= 0.015), and SRF resolution time (OR = 0.46 [95%CI 0.21–1.05]; p= 0.049). EZ restoration time was longer with increasing number of retinal tears (OR = 0.67; [95%CI 0.29–1.52]; p= 0.030), worse final BCVA, and presence of macula-off RRD (OR = 0.26; [95%CI 0.08–0.88]; p= 0.056). SRF resolution time correlated marginally with prone position.Conclusions Residual posterior SRF is more common in eyes with multiple breaks or in myopic eyes. Final BCVA is better in younger subjects and in eyes with shorter duration of RRD. Persistent SRF is a self-limited disorder with a mean resolution of 11.2 months with good visual prognosis improving from a mean baseline logMAR of 1.08 to 0.25 at one year.
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- 2024
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23. Rhegmatogenous retinal detachments in pediatric population.
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Karslioglu, Melisa Zisan, Tas, Ayse Yildiz, Kesim, Cem, Sevgi, Duriye Damla, Sahin, Afsun, Kadayifcilar, Sibel, and Eldem, Bora
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RETINAL detachment ,CHILD patients ,TREATMENT effectiveness ,PROLIFERATIVE vitreoretinopathy ,ETIOLOGY of diseases ,VISUAL acuity - Abstract
Aim: It is to review the clinical features, and surgical, and visual outcomes of rhegmatogenous retinal detachment in a pediatric population. Material and Methods: Medical records of 31 children aged 16 years old or younger with rhegmatogenous retinal detachment were retrospectively analyzed. Cases of acute retinopathy of prematurity were excluded. The data for etiologies, risk factors, prior intraocular surgery, therapeutic approach options, anatomic and functional results were evaluated. Results: Thirty-three eyes of 31 patients with RRD were evaluated. The mean patient age was 11.42±3.82 years (range 3-16). There were 26 (83.9%) males and 5 (16.1%) females. The most common etiology was trauma. At presentation 57.5% of affected eyes (19/33) had a visual acuity worse than 20/400. Preoperative retinal tear was found in 60.6% (20/33) of patients. At initial examination, proliferative vitreoretinopathy was detected in 36.3% (12/33) of patients. The most common primary operation was scleral buckle with subretinal fluid drainage (69.6%, 23/33). Anatomical reattachment was accomplished in 84.8% of cases (28/33). At the final visit, 78.78% of affected eyes (26/33) had a better visual acuity when compared to preoperative examination. In nine of affected eyes (27.27%), visual acuity was 20/200 or better. Mean follow-up time was 37.5 months (range 3-72). Conclusion: In our series, pediatric RRD occurred most commonly in association with trauma. Most eyes were anatomically reattached, and most eyes retained vision of 20/800 or better. Preserving vision in children with RRD is of great importance because of high risk of vision threatening events to the fellow eye. [ABSTRACT FROM AUTHOR]
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- 2020
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24. Visual and Anatomic Outcomes of Cases That Have Received Dexamethasone Implant Treatment for Venous Occlusion.
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VURAL, Esra, KADAYIFCILAR, Sibel, and ELDEM, Bora
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RETINAL vein occlusion , *OPTICAL coherence tomography , *DEXAMETHASONE , *VISUAL acuity , *THERAPEUTICS , *INTRAOCULAR pressure , *RETINAL surgery , *LASER photocoagulation - Abstract
Purpose: To investigate the anatomical and visual results of intravitreal dexamethasone implant treatment for macular edema secondary to retinal vein occlusion. Materials and Methods: The study included a total of 25 patients undergoing dexamethasone implant for macular edema secondary to retinal vein occlusion. Retrospective evaluation included best corrected visual acuity (BCVA) measured with ETDRS charts and macular thickness using optical coherence tomography (OCT) at each visit. The contrast sensitivity levels of patients were evaluated with Pelli-Robson chart. Results: The mean age of the patients was 59.5±13.3 years (range, 34-84years). The mean follow-up time was14.6 ± 5.5 months (range, 6-27 months) and the mean number of implants was 2.6±1.5 (range,1-6). The increase in the visual acuity according to time was statistically significant (p<0.005). The decrease in macular edema was statistically significant (p<0.005). The initial mean contrast sensitivity before implant was 0.72±0.50 log, and the final mean contrast sensitivity was 1.08±0.46 log (p<0.005). No systemic adverse events were observed in any of the cases. When the ocular adverse effects were assessed, cataract progression was seen in 54.5% and cataract operations were performed on 4 patients (18.1%). The increase in intraocular pressure was statistically significant (p<0.005) and only one patient needed medical treatment. Conclusion: Dexamethasone implant had a positive effect on anatomic and visual results in retinal vein occlusion-associated macular edema but the ideal repeat interval for intravitreal dexamethasone treatment should be shorter than 6 months. [ABSTRACT FROM AUTHOR]
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- 2019
25. Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis
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Dick, Andrew D., primary, Rosenbaum, James T., additional, Al-Dhibi, Hassan A., additional, Belfort, Rubens, additional, Brézin, Antoine P., additional, Chee, Soon Phaik, additional, Davis, Janet L., additional, Ramanan, Athimalaipet V., additional, Sonoda, Koh-Hei, additional, Carreño, Ester, additional, Nascimento, Heloisa, additional, Salah, Sawsen, additional, Salek, Sherveen, additional, Siak, Jay, additional, Steeples, Laura, additional, Accorinti, Massimo, additional, Acharya, Nisha, additional, Adan, Alfredo, additional, Agrawal, Rupesh, additional, Akkoc, Nurullah, additional, Al Ghamdi, Saed, additional, Al Ghamdi, Turki, additional, Al Saati, Anood, additional, Alsabaani, Nasser, additional, Al-Shamarani, Mohamed, additional, Bachta, Artur, additional, Barisani-Asenbauer, Talin, additional, Beare, Nicholas, additional, Porto, Fernanda Belga Ottoni, additional, Blanco, Ricardo, additional, Yee, Anita Chan Sook, additional, Chandran, Vinod, additional, Chiquet, Christophe, additional, Chng, Hiok Hee, additional, Cimbalas, Andrius, additional, Cimino, Luca, additional, Cordero-Coma, Miguel, additional, Cristobal, Couto, additional, Cuevas, Miguel, additional, Eurico da Fonseca, João, additional, de Boer, Joke, additional, de la Torre, Alejandra, additional, De Schryver, Ilse, additional, Derzko-Dzulynsky, Larissa, additional, Diaz-Valle, David, additional, Merino, Claudia Eugenia Duran, additional, Facsko, Andrea, additional, Figueira, Luis, additional, Fonollosa, Alejandro, additional, Fortin, Eric, additional, Gale, Richard, additional, Galeazzi, Mauro, additional, Garcia, Sandra, additional, Garcia Ruiz de Morales, Jose Maria, additional, Gašperšič, Nataša, additional, Goldstein, Debra, additional, Guedes, Marta, additional, Guex-Crosier, Yan, additional, Gul, Ahmet, additional, Hamam, Rola, additional, Haroon, Muhammad, additional, Hasegawa, Kenichi, additional, Heiligenhaus, Arnd, additional, Hooper, Claire, additional, Hwang, Yih-Shiou, additional, Hwang, De-Kuang, additional, Juanola, Xavier, additional, Kaburaki, Toshikatsu, additional, Kadayifcilar, Sibel, additional, Kempen, John, additional, Kezuka, Takeshi, additional, Kherani, Amin, additional, Kirsimäe, Maarja, additional, Kotaniemi, Kaisu, additional, Kraut, Aleksandra, additional, Kubicka-Trząska, Agnieszka, additional, Kuffova, Lucia, additional, Lightman, Susan, additional, Lim, Lyndell, additional, Lim, Wee Kiak, additional, McCluskey, Peter, additional, McGuire, Mairide, additional, Mirabelli, Pierfrancesco, additional, Miserocchi, Elisabetta, additional, Misiuk-Hojło, Marta, additional, Muccioli, Cristina, additional, Muñoz, Santiago, additional, Murphy, Conor, additional, Murray, Philip I., additional, Nagy, Zoltan, additional, Namba, Kenichi, additional, Neri, Piergiorgio, additional, Nguyen, Quan, additional, O'Gradaigh, Donncha, additional, Omair, Mohammed, additional, Otsa, Kati, additional, Ozyazgan, Yilmaz, additional, Pablo, Franco, additional, Paroli, Maria Pia, additional, Pleyer, Uwe, additional, Poór, Gyula, additional, Proença, Rui, additional, Rabinovitch, Theodore, additional, Read, Russell, additional, Rebrov, Margarita, additional, Recillas-Gispert, Claudia, additional, Rothova, Aniki, additional, Schwartzman, Sergio, additional, Seve, Pascal, additional, Sharma, Srilakshmi, additional, Sims, Joanne, additional, Sohár, Nicolette, additional, Suhler, Eric, additional, Szántó, Sándor, additional, Szepessy, Zsuzsanna, additional, Tappeiner, Christoph, additional, Thorne, Jennifer, additional, Tugal Tutkun, Ilknur, additional, Turno-Kręcicka, Anna, additional, Van Calster, Joachim, additional, van der Horst-Bruinsma, Irene, additional, Vidovič Valentinčič, Nataša, additional, Vitale, Albert, additional, Voorduin Ramos, Stephanie, additional, Vukojevic, Nenad, additional, Wakefield, Denis, additional, Willermain, François, additional, Yalcindag, Nilufer, additional, Yamamoto, Joyce Hisae, additional, Yeh, Stephen, additional, Zemaitiene, Reda, additional, and Ziouzina, Olga, additional
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- 2018
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26. Fundus autofluorescence and optical coherence tomography findings in glutathione synthetase deficiency
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Şekeroğlu, Hande Taylan, Hismi, Burcu, Kadayifcilar, Sibel, and Coskun, Turgay
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- 2015
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27. INTRAVITREAL DEXAMETHASONE (OZURDEX) IMPLANT FOR RADIATION MACULOPATHY SECONDARY TO STEREOTACTIC RADIOTHERAPY FOR POSTERIOR UVEAL MELANOMA
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Koc, Irem, primary, Kadayifcilar, Sibel, additional, Kiratli, Hayyam, additional, and Eldem, Bora, additional
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- 2017
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28. The Relationship Between Choroidal Expansion and Intraocular Pressure Rise During the Water Drinking Test in Healthy Subjects and Patients With Exfoliation Syndrome
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Kocabeyoglu, Sibel, primary, Uzun, Salih, additional, Kadayifcilar, Sibel, additional, Mocan, Mehmet C., additional, and Irkec, Murat, additional
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- 2016
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29. Safety and Efficacy of Gevokizumab in Patients with Behçet’s Disease Uveitis: Results of an Exploratory Phase 2 Study
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Tugal-Tutkun, Ilknur, primary, Kadayifcilar, Sibel, additional, Khairallah, Moncef, additional, Lee, Sung Chul, additional, Ozdal, Pinar, additional, Özyazgan, Yilmaz, additional, Song, Ji Hun, additional, Yu, Hyeong Gon, additional, Lehner, Valerie, additional, de Cordoue, Agnès, additional, Bernard, Oana, additional, and Gül, Ahmet, additional
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- 2016
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30. Hyperbaric Oxygen Therapy in Branch Retinal Artery Occlusion in a 15-Year-Old Boy with Methylenetetrahydrofolate Reductase Mutation
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Celebi, Ali Riza Cenk, primary, Kadayifcilar, Sibel, additional, and Eldem, Bora, additional
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- 2015
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31. Safety and Efficacy of Gevokizumab in Patients with Behçet's Disease Uveitis: Results of an Exploratory Phase 2 Study.
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Tugal-Tutkun MD, Ilknur, Kadayifcilar MD, Sibel, Khairallah MD, Moncef, Lee, Sung Chul, Ozdal, Pinar, Özyazgan, Yilmaz, Song MD, Ji Hun, Yu, Hyeong Gon, Lehner, Valerie, de Cordoue MD, Agnès, Bernard MD, Oana, Gül MD, Ahmet, Tugal-Tutkun, Ilknur Md, Kadayifcilar, Sibel Md, Khairallah, Moncef Md, Lee, Sung Chul Md PhD, Song, Ji Hun Md, Yu, Hyeong Gon Md PhD, Lehner, Valerie PhD, and de Cordoue, Agnès Md
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DISEASE exacerbation ,UVEITIS ,EYE inflammation ,UVEAL diseases ,ADRENOCORTICAL hormones ,THERAPEUTIC use of monoclonal antibodies ,SUBCUTANEOUS injections ,BEHCET'S disease ,CLINICAL trials ,COMPARATIVE studies ,GLUCOCORTICOIDS ,IMMUNOSUPPRESSIVE agents ,INTRAVENOUS injections ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,MONOCLONAL antibodies ,RESEARCH ,VISUAL acuity ,EVALUATION research ,RANDOMIZED controlled trials ,TREATMENT effectiveness - Abstract
Purpose: To evaluate the safety and efficacy of gevokizumab for the treatment of Behçet's disease uveitis in a prospective, open-label, randomized phase 2 trial.Methods: Behçet's disease patients with new acute ocular exacerbation or at risk of exacerbation received 30 or 60 mg gevokizumab every 4 weeks intravenously or subcutaneously, on top of a stable regimen of immunosuppressives and corticosteroids (≤20 mg/day equivalent prednisolone). Patients withdrew in cases of ocular exacerbation.Results: A total of 21 patients were included (17 acute and 4 at-risk; mean duration of uveitis 45.6 ± 37.4 months). There were no serious adverse events related to gevokizumab. Recorded adverse events were mostly associated with exacerbation of uveitis or its complications. Response was evaluated for 14 acute patients and all showed rapid control of acute ocular exacerbation, mostly within 1 week, without any increase in corticosteroid dosage.Conclusions: Gevokizumab was well tolerated and rapidly controlled acute ocular exacerbations of Behçet's disease uveitis without the need for high-dose corticosteroid. [ABSTRACT FROM AUTHOR]- Published
- 2017
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32. Prepapillary vascular loop-a new classification
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Hana A Mansour, Jerald A. Bovino, Ali Osman Saatci, Thomas R. Hedges, Sami H. Uwaydat, Igor Kozak, Ana Honrubia, Elisa Carreras, Thomas M. Aaberg, Alex P. Hunyor, Jay Chhablani, Giacomo Panozzo, Francisco J. Ascaso, Laura Broc, Jesús Díaz, Jaume Català, Ahmad M. Mansour, Sibel Kadayifcilar, Eman Al Kahtani, Maurizio Battaglia, Nuria Olivier, Laura Gutierrez, Pablo Gili, Hashim Ali Khan, Luiz H. Lima, Mansour, Ahmad M, Kozak, Igor, Saatci, Ali Osman, Ascaso, Francisco J, Broc, Laura, Battaglia Parodi, Maurizio, Olivier, Nuria, Gili, Pablo, Chhablani, Jay, Hedges, Thomas R, Honrubia, Ana, Gutierrez, Laura, Panozzo, Giacomo, Català, Jaume, Díaz, Jesú, Carreras, Elisa, Kadayifcilar, Sibel, Al Kahtani, Eman S, Uwaydat, Sami H, Lima, Luiz H, Mansour, Hana A, Khan, Hashim Ali, Aaberg, Thomas M, Bovino, Jerald A, and Hunyor, Alex P
- Subjects
medicine.medical_specialty ,Vascular Malformations ,Lumen (anatomy) ,Asymptomatic ,Article ,Pathogenesis ,03 medical and health sciences ,0302 clinical medicine ,Branch retinal artery occlusion ,Ophthalmology ,medicine ,Humans ,Eye Abnormalities ,Hyaline ,Retrospective Studies ,business.industry ,Retinal Vessels ,Amaurosis fugax ,Retinal vascular tortuosity ,medicine.disease ,Peripheral ,030221 ophthalmology & optometry ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
BACKGROUND/OBJECTIVES: To analyze the ophthalmic characteristics of congenital prepapillary vascular loop (PVL) and to propose a new morphologic classification dividing the loops into six types. SUBJECTS/METHODS: Collaborative multinational multicentre retrospective study of PVL cases. RESULTS: There was a total of 49 cases (61 eyes), 37 unilateral (75.5%) and 12 bilateral (24.5%), 32 arterial type (65.3%) and 18 venous type (36.7%) (one patient had either kind in each eye). The mean number of loops per eye was 2.7 (range, 1-7). The loops were asymptomatic in 42 cases (85.7%). Other findings included: the presence of cilioretinal artery (14 cases), retinal vascular tortuosity (26 cases), amaurosis fugax (1 case), branch retinal artery occlusion (1 case) and vitreous haemorrhage (3 cases). Six morphologic loop types could be discerned based on elevation (flat vs. elevated), shape (figure of 8 or corkscrew with hyaline sheath), number (multiple or single), location (central or peripheral), lumen size (arterial vs. arteriolar) and presence of vascular tortuosity or vitreous traction. CONCLUSIONS: PVL are usually asymptomatic and can be divided into six morphologic types with different pathogenesis during early embryogenesis.
- Published
- 2020
33. Genotypic-phenotypic features and enzyme replacement therapy outcome in patients with mucopolysaccharidosis VI from Turkey
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Handan Turan-Dizdar, Umut Arslan, Ayşegül Tokatlı, Deniz Dogru, Burhanettin Gönüldaş, Mustafa Kılıç, Sibel Kadayifcilar, Hatice-Serap Sivri, Aydan Genç, Cemalettin Aksoy, Sema Savci, Turgay Coşkun, Didem Yücel-Yılmaz, Ali Dursun, Dursun Alehan, Rıza Köksal Özgül, Mehmet Karaca, Melda Saglam, [Kilic, Mustafa] Sami Ulus Children Hosp, Div Metab, Babur Cad 44, TR-06080 Ankara, Turkey -- [Dursun, Ali -- Coskun, Turgay -- Tokatli, Aysegul -- Ozgul, Riza K. -- Yucel-Yilmaz, Didem -- Sivri, Hatice-Serap] Hacettepe Univ, Children Hosp, Div Metab, Ankara, Turkey -- [Karaca, Mehmet] Aksaray Univ, Fac Sci & Arts, Dept Biol, Aksaray, Turkey -- [Dogru, Deniz] Hacettepe Univ, Div Pediat Pulmonol, Children Hosp, Ankara, Turkey -- [Alehan, Dursun] Hacettepe Univ, Div Pediat Cardiol, Children Hosp, Ankara, Turkey -- [Kadayifcilar, Sibel] Hacettepe Univ, Dept Ophthalmol, Fac Med, Ankara, Turkey -- [Genc, Aydan -- Turan-Dizdar, Handan] Hacettepe Univ, Div Audiol, Dept Ear Nose Throat, Fac Med, Ankara, Turkey -- [Gonuldas, Burhanettin] Hacettepe Univ, Dept Ear Nose Throat, Fac Med, Ankara, Turkey -- [Savci, Sema -- Saglam, Melda] Hacettepe Univ, Dept Physiotheraphy & Rehabil, Fac Hlth Sci, Ankara, Turkey -- [Aksoy, Cemalettin] Hacettepe Univ, Dept Orthopaed & Traumatol, Fac Med, Ankara, Turkey -- [Arslan, Umut] Hacettepe Univ, Dept Biostat, Fac Med, Ankara, Turkey, Ozgul, Riza Koksal -- 0000-0002-0283-635X, Mustafa -- 0000-0002-1401-5233, and Sabire Yazıcı Fen Edebiyat Fakültesi
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0301 basic medicine ,Adult ,Male ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Adolescent ,Turkey ,N-Acetylgalactosamine-4-Sulfatase ,Urinary system ,genotype ,Mucopolysaccharidosis type VI ,Gastroenterology ,Dermatan sulfate ,03 medical and health sciences ,chemistry.chemical_compound ,Young Adult ,Gene Frequency ,Internal medicine ,Genotype ,Genetics ,medicine ,Humans ,Enzyme Replacement Therapy ,Chondroitin sulfate ,Respiratory system ,Child ,Genetics (clinical) ,Genetic Association Studies ,mucopolysaccharidosis type VI ,Mucopolysaccharidosis VI ,business.industry ,Infant, Newborn ,nutritional and metabolic diseases ,Infant ,Enzyme replacement therapy ,Lysosomal Storage Diseases ,030104 developmental biology ,chemistry ,Child, Preschool ,outcome ,Quality of Life ,Female ,business - Abstract
WOS: 000413425400010, PubMed: 28884960, Mucopolysaccharidosis type VI (MPS VI) is a lysosomal storage disorder (LSD) characterized by a chronic, progressive course with multiorgan involvement. In our study, clinical, biochemical, molecular findings, and response to enzyme replacement therapy (ERT) for at least 6 months were evaluated in 20 patients with MPS VI. Treatment effects on clinical findings such as liver and spleen sizes, cardiac and respiratory parameters, visual and auditory changes, joints' range of motions, endurance tests and changes in urinary glycosaminoglycan excretions, before and after ERT were analyzed. ERT caused increased physical endurance and decreased urinary dermatan sulfate/chondroitin sulfate ratios. Changes in growth parameters, cardiac, respiratory, visual, auditory findings, and joint mobility were not significant. All patients and parents reported out an increased quality of life, which were not correlated with clinical results. The most prevalent mutation was p.L321P, accounting for 58.8% of the mutant alleles and two novel mutations (p.G79E and p.E390K) were found. ERT was a safe but expensive treatment for MPS VI, with mild benefits in severely affected patients. Early treatment with ERT is mandatory before many organs and systems are involved.
- Published
- 2017
34. Recovery course of persistent posterior subretinal fluid after successful repair of rhegmatogenous retinal detachment.
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Mansour AM, López-Guajardo L, Belotto S, Lima LH, Charbaji AR, Schwartz SG, Wu L, Smiddy WE, Ascaso J, Jürgens I, Foster RE, Elnahry AG, Sinawat S, Pinilla I, Pérez-Salvador García E, Suarez Leoz M, Olivier Pascual N, Zago Ribeiro L, Arroyo Castillo R, Navea A, Kadayifcilar S, Ellabban AA, Rey A, Mansour HA, Tripathy K, Kozak I, Uwaydat SH, Valero MS, Cobo-Soriano R, Díaz-Barreda MD, Monje Fernández L, González Del Valle F, López Liroz I, Vazquez Cruchaga E, Fonollosa A, Esteban Floria O, Relimpio Lopez MI, Shah G, Wingelaar MJ, Ravani R, Donate-López J, Rubio Velázquez E, and Parodi M
- Abstract
Purpose: To investigate best corrected visual acuity (BCVA), subretinal fluid (SRF) absorption time or ellipsoid zone (EZ) restoration time and various variables in patients with persistent SRF after successful primary repair of rhegmatogenous retinal detachment (RRD)., Methods: This retrospective multicenter study allowed independent analysis of the healing pattern by two observers based on composite of serial cross-sectional macular optical coherence tomography (OCT) scans. Univariate and multivariate analyses were implemented., Results: One hundred and three cases had persistent SRF after pars plana vitrectomy, scleral buckling, or pneumatic retinopexy. By univariate analysis, SRF resolution time correlated positively with the number of retinal breaks ( p < 0.001) and with increased myopia ( p = 0.011). Using multivariate analysis, final BCVA (log MAR) correlated positively with age, duration of RRD, initial BCVA (OR = 3.28; [95%CI = 1.44-7.47]; p = 0.015), and SRF resolution time (OR = 0.46 [95%CI 0.21-1.05]; p = 0.049). EZ restoration time was longer with increasing number of retinal tears (OR = 0.67; [95%CI 0.29-1.52]; p = 0.030), worse final BCVA, and presence of macula-off RRD (OR = 0.26; [95%CI 0.08-0.88]; p = 0.056). SRF resolution time correlated marginally with prone position., Conclusions: Residual posterior SRF is more common in eyes with multiple breaks or in myopic eyes. Final BCVA is better in younger subjects and in eyes with shorter duration of RRD. Persistent SRF is a self-limited disorder with a mean resolution of 11.2 months with good visual prognosis improving from a mean baseline logMAR of 1.08 to 0.25 at one year., Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2023
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35. [Pediatric-onset adult type sarcoidosis: A case report].
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Ozsurekci Y, Cengiz AB, Duzova A, Sag E, Kadayifcilar S, Dogru Ersoz D, Akcoren Z, Yuce A, Tavil B, Ayvaz D, Akyuz C, and Kara Eroglu F
- Subjects
- Age of Onset, Child, Female, Humans, Sarcoidosis diagnosis
- Abstract
Sarcoidosis, a multisystem disorder of unknown etiology that involves multiple organs, is rare in children. The true incidence and prevalence of childhood sarcoidosis is unknown. As in adults, many children with sarcoidosis may be asymptomatic; the disease may remain undiagnosed. A complete and systematic evaluation of the patient is essential for the sarcoidosis diagnosis in children. Here, we describe a case of 12-year-old female who presented with 2 years history of uveitis and hepatosplenomegaly. A chest computerized tomography revealed scattered peripheral pulmonary nodules and bilateral hiliar lymphadenopathy. Bone marrow aspiration and liver biopsy were not diagnostic. A lung biopsy showed non-necrotizing epithelioid cell granulomas. She was diagnosed with sarcoidosis according to demonstration of granulomatous inflammation and the exclusion of confusable entities
- Published
- 2015
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