146 results on '"Korkmaz, Brice"'
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2. Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial
3. Cathepsin C role in inflammatory gastroenterological, renal, rheumatic, and pulmonary disorders
4. Activation of neutrophil elastase-related serine proteases in myelomonocytic cells
5. Neutrophils play a major role in the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters
6. Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease
7. Differences in Staining for Neutrophil Elastase and its Controlling Inhibitor SLPI Reveal Heterogeneity among Neutrophils in Psoriasis
8. Cathepsin C role in inflammatory gastroenterological, renal, rheumatic, and pulmonary disorders
9. Preservation with α1-antitrypsin improves primary graft function of murine lung transplants
10. Preservation solution Custodiol containing human alpha-1-antitrypsin improves graft recovery after prolonged cold ischemic storage in a rat model of heart transplantation
11. Consequences of pharmacological inhibition of cathepsin C using IcatCXPZ-01on maturation of granzyme zymogens in cytotoxic lymphocytes
12. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S
13. Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation
14. Additional file 1 of Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial
15. Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation
16. Targeting Cathepsin C in PR3-ANCA Vasculitis
17. Neutrophils initiate the destruction of the olfactory epithelium during SARS-CoV-2 infection in hamsters
18. Bile Acids: Key Players in Inflammatory Bowel Diseases?
19. The discovery of the Papillon-Lefèvre syndrome, a rare cathepsin C related lysosomal disease
20. Cathepsin C inhibition as a potential treatment strategy in cancer
21. Analysis of urinary cathepsin C for diagnosing Papillon–Lefèvre syndrome
22. Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe
23. Gut Serpinome: Emerging Evidence in IBD
24. Pathogenicity of Proteinase 3-Anti-Neutrophil Cytoplasmic Antibody in Granulomatosis With Polyangiitis: Implications as Biomarker and Future Therapies
25. 4C3 Human Monoclonal Antibody: A Proof of Concept for Non-pathogenic Proteinase 3 Anti-neutrophil Cytoplasmic Antibodies in Granulomatosis With Polyangiitis
26. Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia
27. Lung Protection by Cathepsin C Inhibition: A New Hope for COVID-19 and ARDS?
28. Human proteinase 3 resistance to inhibition extends to alpha‐2 macroglobulin
29. Proteinase 3 phosphonic inhibitors
30. Processing and Maturation of Cathepsin C Zymogen: A Biochemical and Molecular Modeling Analysis
31. Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis
32. Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C
33. Structure‐based design and in vivo anti‐arthritic activity evaluation of a potent cyclopropyl peptidyl nitrile inhibitor of cathepsin C
34. 196. CHARACTERIZATION OF CATHEPSIN C AS A TREATMENT TARGET IN ANCA-ASSOCIATED VASCULITIS
35. Therapeutic targeting of cathepsin C: from pathophysiology to treatment
36. Human proteinase 3 resistance to inhibition extends to alpha‐2 macroglobulin.
37. Exploiting the S4–S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis
38. Pharmacological Cathepsin C Inactivation Eliminates Proteinase 3, the Antigen in Autoimmune Vasculitis
39. Exploiting the S4–S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis
40. Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases
41. Inhibition of soluble and membrane‐bound neutrophil elastase by inhibitor POL6014
42. Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples
43. Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense
44. Neutrophils can disarm NK cell response through cleavage of NKp46
45. Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
46. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases
47. Neutrophil serine proteases exert proteolytic activity on endothelial cells
48. Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense.
49. NEW SELECTIVE PEPTIDYL DI(CHLOROPHENYL)‐PHOSPHONATE ESTERS TO VISUALIZE AND BLOCK NEUTROPHIL PROTEINASE 3 IN HUMAN DISEASES
50. New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases
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