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Your search keyword '"Lei, Zhihui"' showing total 22 results
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22 results on '"Lei, Zhihui"'

3. Magnetic Induction Heating in a Conducting Polymer for Biomedical Applications

Author

Lei, Zhihui, Chen, Shun, Liao, Yu, Liu, Wendong, Zhou, Lian, Fu, Benwei, Tao, Peng, Shang, Wen, Liu, Jie, Hou, Cuilan, Song, Chengyi, and Deng, Tao

Abstract

In this study, we investigate the magnetic induction heating induced in a conducting polymer (CP) under alternative magnetic fields (AMFs). Experimental results and numerical simulations have proved that the magneto-thermal conversion of the CP is caused by the induced eddy current, which is related to the shape and intensity of the applied external AMF, and the intrinsic electrical conductivity, macrostructure and microstructure of the CP. By employing various fabrication methods, specific temperature distribution and control of thermal field within conducting polymer films and aerogels could be achieved. To exploit the potential of magnetic induction heating in CP for biomedical applications, we designed a conducting polymer aerogel-based self-adaptive heat patch and demonstrated its AMF-enabled localized heating of skin. In addition to the thermal ablation of tumor cells via magneto-thermal conversion of the CP, the promotion of neuronal differentiation at mild temperature by noninvasive magneto-electrical stimulation has also been demonstrated to be an effective strategy for tissue engineering.

Published
2024
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15. Genome-Wide Selective Signatures Reveal Candidate Genes Associated with Hair Follicle Development and Wool Shedding in Sheep

Author

Lei, Zhihui, primary, Sun, Weibo, additional, Guo, Tingting, additional, Li, Jianye, additional, Zhu, Shaohua, additional, Lu, Zengkui, additional, Qiao, Guoyan, additional, Han, Mei, additional, Zhao, Hongchang, additional, Yang, Bohui, additional, Zhang, Liping, additional, Liu, Jianbin, additional, Yuan, Chao, additional, and Yue, Yaojing, additional

Published
2021
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17. The mechanism of Cu (II) adsorption onto 2,3-dialdehyde nano-fibrillated celluloses

Author

Wenhua Gao, Jinsong Zeng, Jun Xu, Lei Zhihui, and Bin Wang

Subjects
Aqueous solution, Polymers and Plastics, Metal ions in aqueous solution, Organic Chemistry, Inorganic chemistry, Enthalpy, Periodate, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Gibbs free energy, symbols.namesake, chemistry.chemical_compound, Adsorption, chemistry, Chemisorption, Specific surface area, Materials Chemistry, symbols, 0210 nano-technology
Abstract

Nano-fibrillated celluloses (NFCs) were separated from bleached softwood kraft pulp. Through the periodate oxidation method, 2,3-dialdehyde nano-fibrillated celluloses (DNFCs) with varied aldehyde content were prepared. The high aldehyde content, large specific surface area and high surface charge density of DNFCs benefited the adsorbing of Cu (II). The adsorption kinetics and isotherms presented good correlations with the Pseudo-second-order model and Freundlich model, respectively. Both physical and chemical adsorptions existed in the Cu (II) adsorption by DNFCs, while chemisorption was the rate-limiting step. The adsorption thermodynamic parameters Gibbs free energy change (ΔG), enthalpy change (ΔH) and entropy change (ΔS) were also investigated. This study provides theoretical support for applying DNFCs to remove metal ions from aqueous solutions.

Published
2020

22. Combined Intracoronary Prourokinase Thrombolysis on Myocardial Perfusion and Vascular Endothelial Function in STEMI.

Author

Che S, Guo X, Lei Z, and Lin S

Subjects
Humans, Male, Middle Aged, Female, Aged, Endothelium, Vascular physiopathology, Endothelium, Vascular drug effects, Treatment Outcome, Urokinase-Type Plasminogen Activator administration & dosage, Fibrinolytic Agents administration & dosage, Fibrinolytic Agents therapeutic use, Fibrinolytic Agents adverse effects, Recombinant Proteins, ST Elevation Myocardial Infarction physiopathology, ST Elevation Myocardial Infarction therapy, ST Elevation Myocardial Infarction surgery, Percutaneous Coronary Intervention, Thrombolytic Therapy methods, Thrombolytic Therapy adverse effects
Abstract

Background: This study aimed to investigate the effects of intracoronary prourokinase thrombolysis combined with emergency percutaneous coronary intervention (PCI) on myocardial perfusion and vascular endothelial function in patients with acute ST-segment elevation myocardial infarction (STEMI)., Methods: A total of 104 patients with STEMI were collected from August 2020 to August 2022, and were divided into control group and observation group in a random manner. The control group received PCI directly, and the observation group received intracoronary prourokinase thrombolytic therapy before PCI. The treatment effects were evaluated by measuring the cardiac function indexes, including left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), and left ventricular ejection fraction (LVEF), the TIMI myocardial perfusion grade, the vascular endothelial indexes, including soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1), the von Willebrand factor (vWF), the myocardial injury indexes, including cardiac troponin I (cTnI), creatine kinase isoenzyme MB (CK-MB), and lactate dehydrogenase (LDH), and the inflammatory factors, including myeloperoxidase (MPO), C-reactive protein (CRP), and interleukin-6 (IL-6). Furthermore, the treatment safety was assessed by recording the incidence of major MACE events, 6 months after the operation., Results: After treatment, LVEDD and LVESD were lower in the observation group than in the control group, and LVEF was higher (p < 0.05). The TIMI myocardial perfusion grade in the observation group was higher than in the control group, after treatment (p < 0.05). The levels of sICAM-1, sVCAM-1, and vWF were higher in the observation group than in the control group (p < 0.05). The levels of cTnI, CK-MB, and LDH in the observation group were lower than those in the control group, 24 hours after surgery. At 3 days after surgery, MPO was lower in the observation group than in the control group, and CRP and IL-6 were higher (p < 0.05). The incidence of major MACE events in the observation group was lower than that in the control group, 6 months after surgery (p < 0.05). There was 1 case of puncture site bleeding in the observation group, 1 case of puncture site bleeding and 1 case of subcutaneous ecchymosis in the control group, but no serious bleeding events, such as internal bleeding or cerebral hemorrhage, in the two groups., Conclusions: Intracoronary prourokinase thrombolytic therapy combined with emergency PCI can promote the recovery of cardiac function, improve myocardial perfusion and vascular endothelial function, and reduce inflammation and the incidence of major postoperative MACE events in acute STEMI patients.

Published
2024
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