Search

Your search keyword '"Lengfelder, Eva"' showing total 119 results
Start Over Author "Lengfelder, Eva" Publication Year Range Last 10 years
119 results on '"Lengfelder, Eva"'

1. Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study

Author

Niederwieser, Dietger, Lang, Thomas, Krahl, Rainer, Heinicke, Thomas, Maschmeyer, Georg, Al-Ali, Haifa Kathrin, Schwind, Sebastian, Jentzsch, Madlen, Cross, Michael, Kahl, Christoph, Wolf, Hans-Heinrich, Sayer, Herbert, Schulze, Antje, Dreger, Peter, Hegenbart, Ute, Krämer, Alwin, Junghanss, Christian, Mügge, Lars-Olof, Hähling, Detlev, Hirt, Carsten, Späth, Christian, Peter, Norma, Opitz, Bernhard, Florschütz, Axel, Reifenrath, Kolja, Zojer, Niklas, Scholl, Sebastian, Pönisch, Wolfram, Heyn, Simone, Vucinic, Vladan, Hochhaus, Andreas, Aul, Carlo, Giagounidis, Aristoteles, Balleisen, Leopold, Oldenkott, Bernd, Staib, Peter, Kiehl, Michael, Schütte, Wolfgang, Naumann, Ralph, Eimermacher, Hartmut, Dörken, Bernd, Sauerland, Cristina, Lengfelder, Eva, Hiddemann, Wolfgang, Wörmann, Bernhard, Müller-Tidow, Carsten, Serve, Hubert, Schliemann, Christoph, Hehlmann, Rüdiger, Berdel, Wolfgang E., Pfirrmann, Markus, Krug, Utz, and Hoffmann, Verena S.

Published
2023
Full Text
View/download PDF

5. Publisher Correction: Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide—an International Collaborative Study

Author

Kayser, Sabine, Rahmé, Ramy, Martínez-Cuadrón, David, Ghiaur, Gabriel, Thomas, Xavier, Sobas, Marta, Guerci-Bresler, Agnes, Garrido, Ana, Pigneux, Arnaud, Gil, Cristina, Raffoux, Emmanuel, Tormo, Mar, Vey, Norbert, de la Serna, Javier, Salamero, Olga, Lengfelder, Eva, Levis, Mark J., Fenaux, Pierre, Sanz, Miguel A., Platzbecker, Uwe, Schlenk, Richard F., Adès, Lionel, and Montesinos, Pau

Published
2021
Full Text
View/download PDF

7. Frontline therapy of acute promyelocytic leukemia: Randomized comparison of ATRA and intensified chemotherapy versus ATRA and anthracyclines

Author

Lengfelder, Eva, Görlich, Dennis, Nowak, Daniel, Spiekermann, Karsten, Haferlach, Claudia, Krug, Utz, Kreuzer, Karl‐Anton, Braess, Jan, Schliemann, Christoph, Lindemann, Hans‐Walter, Horst, Heinz A., Schiel, Xaver, Flasshove, Michael, Hecht, Anna, Schnittger, Susanne, Schneider, Stephanie, Wörmann, Bernhard, Hofmann, Wolf‐Karsten, Berdel, Wolfgang E., Bormann, Eike, Sauerland, Cristina, Büchner, Thomas, and Hiddemann, Wolfgang

Published
2018
Full Text
View/download PDF

12. Rituximab Maintenance Versus Observation After Immunochemotherapy (R-CHOP, R-MCP, and R-FCM) in Untreated Follicular Lymphoma Patients: A Randomized Trial of the Ostdeutsche Studiengruppe Hämatologie und Onkologie and the German Low-Grade Lymphoma Study Group

Author

Hirt, Carsten, primary, Hoster, Eva, additional, Unterhalt, Michael, additional, Hänel, Mathias, additional, Prange-Krex, Gabriele, additional, Forstpointner, Roswitha, additional, Florschütz, Axel, additional, Graeven, Ullrich, additional, Frickhofen, Norbert, additional, Wulf, Gerald, additional, Lengfelder, Eva, additional, Lerchenmüller, Christian, additional, Schlag, Rudolf, additional, Dierlamm, Judith, additional, Fischer von Weikersthal, Ludwig, additional, Ahmed, Asima, additional, Harich, Hanns-Detlev, additional, Rosenwald, Andreas, additional, Klapper, Wolfram, additional, Dreyling, Martin, additional, Hiddemann, Wolfgang, additional, and Herold, Michael, additional

Published
2021
Full Text
View/download PDF

13. Leitlinie - Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie h��matologischer und onkologischer Erkrankungen

Author

Koschmieder, Steffen, ��sterreichische Gesellschaft F��r H��matologie & Medizinische Onkologie, Schweizerische Gesellschaft F��r H��matologie, Baerlocher, Gabriela M., Petrides, Petro E., D��hner, Konstanze, Schweizerische Gesellschaft F��r Medizinische Onkologie, Lengfelder, Eva, Griesshammer, Martin, Ernst, Thomas, Deutsche Gesellschaft F��r H��matologie Und Medizinische Onkologie, and Gisslinger, Heinz

Subjects
Medizin und Gesundheit
Published
2021
Full Text
View/download PDF

14. Leitlinie : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen : ICD-10 D47.1

Author

Koschmieder, Steffen, Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Schweizerische Gesellschaft Für Hämatologie, Baerlocher, Gabriela M., Petrides, Petro E., Döhner, Konstanze, Schweizerische Gesellschaft Für Medizinische Onkologie, Lengfelder, Eva, Griesshammer, Martin, Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie, Gisslinger, Heinz, and Kröger, Nicolaus

Subjects
Medizin und Gesundheit
Published
2021
Full Text
View/download PDF

15. Leitlinie : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie h��matologischer und onkologischer Erkrankungen

Author

��sterreichische Gesellschaft F��r H��matologie & Medizinische Onkologie, Schweizerische Gesellschaft F��r H��matologie, Petrides, Petro E., Schweizerische Gesellschaft F��r Medizinische Onkologie, Lengfelder, Eva, Griesshammer, Martin, and Deutsche Gesellschaft F��r H��matologie Und Medizinische Onkologie

Subjects
Medizin und Gesundheit
Published
2021
Full Text
View/download PDF

16. Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide: an international collaborative study

Author

Kayser, Sabine, primary, Schlenk, Richard F., additional, Lebon, Delphine, additional, Carre, Martin, additional, Götze, Katharina S., additional, Stölzel, Friedrich, additional, Berceanu, Ana, additional, Schäfer-Eckart, Kerstin, additional, Peterlin, Pierre, additional, Hicheri, Yosr, additional, Rahme, Ramy, additional, Raffoux, Emmanuel, additional, Chermat, Fatiha, additional, Krause, Stefan W., additional, Aulitzky, Walter E., additional, Rigaudeau, Sophie, additional, Noppeney, Richard, additional, Berthon, Celine, additional, Görner, Martin, additional, Jost, Edgar, additional, Carassou, Philippe, additional, Keller, Ulrich, additional, Orvain, Corentin, additional, Braun, Thorsten, additional, Saillard, Colombe, additional, Arar, Ali, additional, Kunzmann, Volker, additional, Wemeau, Mathieu, additional, De Wit, Maike, additional, Niemann, Dirk, additional, Bonmati, Caroline, additional, Schwänen, Carsten, additional, Abraham, Julie, additional, Aljijakli, Ahmad, additional, Haiat, Stephanie, additional, Krämer, Alwin, additional, Reichle, Albrecht, additional, Gnadler, Martina, additional, Willekens, Christophe, additional, Spiekermann, Karsten, additional, Hiddemann, Wolfgang, additional, Müller-Tidow, Carsten, additional, Thiede, Christian, additional, Röllig, Christoph, additional, Serve, Hubert, additional, Bornhäuser, Martin, additional, Baldus, Claudia D., additional, Lengfelder, Eva, additional, Fenaux, Pierre, additional, Platzbecker, Uwe, additional, and Adès, Lionel, additional

Published
2021
Full Text
View/download PDF

17. Characteristics and outcome of patients with low-/intermediate-risk acute promyelocytic leukemia treated with arsenic trioxide - an international collaborative study

Author

Kayser, Sabine, Schlenk, Richard F., Lebon, Delphine, Carre, Martin, Götze, Katharina S., Stölzel, Friedrich, Berceanu, Ana, Schäfer-Eckart, Kerstin, Peterlin, Pierre, Hicheri, Yosr, Rahme, Ramy, Raffoux, Emmanuel, Chermat, Fatiha, Krause, Stefan W., Aulitzky, Walter E., Rigaudeau, Sophie, Noppeney, Richard, Berthon, Celine, Görner, Martin, Jost, Edgar, Carassou, Philippe, Keller, Ulrich, Orvain, Corentin, Braun, Thorsten, Saillard, Colombe, Arar, Ali, Kunzmann, Volker, Wemeau, Mathieu, De Wit, Maike, Niemann, Dirk, Bonmati, Caroline, Schwänen, Carsten, Abraham, Julie, Aljijakli, Ahmad, Haiat, Stephanie, Krämer, Alwin, Reichle, Albrecht, Gnadler, Martina, Willekens, Christophe, Spiekermann, Karsten, Hiddemann, Wolfgang, Müller-Tidow, Carsten, Thiede, Christian, Röllig, Christoph, Serve, Hubert, Bornhäuser, Martin, Baldus, Claudia D., Lengfelder, Eva, Fenaux, Pierre, Platzbecker, Uwe, and Adès, Lionel

Subjects
ddc
Published
2020

18. Leitlinie : ICD10: C92.4 : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen

Author

Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Schweizerische Gesellschaft Für Hämatologie, Döhner, Konstanze, Schlenk, Richard Friedrich, Schweizerische Gesellschaft Für Medizinische Onkologie, Lengfelder, Eva, Lambert, Jean-Francois, Platzbecker, Uwe, Niederwieser, Dietger, Thol, Felicitas, Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie, and Nachbaur, David

Subjects
Medizin und Gesundheit
Published
2020
Full Text
View/download PDF

19. RNA-sequencing of acute promyelocytic leukemia primary blasts reveals novel molecular biomarkers of early death events

Author

Jann, Johann-Christoph, primary, Streuer, Alexander, additional, Hecht, Anna, additional, Nolte, Florian, additional, Nowak, Verena, additional, Danner, Justine, additional, Obländer, Julia, additional, Palme, Iris, additional, Lengfelder, Eva, additional, Platzbecker, Uwe, additional, Hofmann, Wolf-Karsten, additional, Flach, Johanna, additional, and Nowak, Daniel, additional

Published
2020
Full Text
View/download PDF

20. Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide—an International Collaborative Study

Author

Kayser, Sabine, primary, Rahmé, Ramy, additional, Martínez-Cuadrón, David, additional, Ghiaur, Gabriel, additional, Thomas, Xavier, additional, Sobas, Marta, additional, Guerci-Bresler, Agnes, additional, Garrido, Ana, additional, Pigneux, Arnaud, additional, Gil, Cristina, additional, Raffoux, Emmanuel, additional, Tormo, Mar, additional, Vey, Norbert, additional, de la Serna, Javier, additional, Salamero, Olga, additional, Lengfelder, Eva, additional, Levis, Mark J., additional, Fenaux, Pierre, additional, Sanz, Miguel A., additional, Platzbecker, Uwe, additional, Schlenk, Richard F., additional, Adès, Lionel, additional, and Montesinos, Pau, additional

Published
2020
Full Text
View/download PDF

21. Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial

Author

Poeschel, Viola, primary, Held, Gerhard, additional, Ziepert, Marita, additional, Witzens-Harig, Mathias, additional, Holte, Harald, additional, Thurner, Lorenz, additional, Borchmann, Peter, additional, Viardot, Andreas, additional, Soekler, Martin, additional, Keller, Ulrich, additional, Schmidt, Christian, additional, Truemper, Lorenz, additional, Mahlberg, Rolf, additional, Marks, Reinhard, additional, Hoeffkes, Heinz-Gert, additional, Metzner, Bernd, additional, Dierlamm, Judith, additional, Frickhofen, Norbert, additional, Haenel, Mathias, additional, Neubauer, Andreas, additional, Kneba, Michael, additional, Merli, Francesco, additional, Tucci, Alessandra, additional, de Nully Brown, Peter, additional, Federico, Massimo, additional, Lengfelder, Eva, additional, di Rocco, Alice, additional, Trappe, Ralf, additional, Rosenwald, Andreas, additional, Berdel, Christian, additional, Maisenhoelder, Martin, additional, Shpilberg, Ofer, additional, Amam, Josif, additional, Christofyllakis, Konstantinos, additional, Hartmann, Frank, additional, Murawski, Niels, additional, Stilgenbauer, Stephan, additional, Nickelsen, Maike, additional, Wulf, Gerald, additional, Glass, Bertram, additional, Schmitz, Norbert, additional, Altmann, Bettina, additional, Loeffler, Markus, additional, and Pfreundschuh, Michael, additional

Published
2019
Full Text
View/download PDF

22. Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial

Author

Poeschel, Viola, Held, Gerhard, Ziepert, Marita, Witzens-Harig, Mathias, Holte, Harald, Thurner, Lorenz, Borchmann, Peter, Viardot, Andreas, Soekler, Martin, Keller, Ulrich, Schmidt, Christian, Truemper, Lorenz, Mahlberg, Rolf, Marks, Reinhard, Hoeffkes, Heinz-Gert, Metzner, Bernd, Dierlamm, Judith, Frickhofen, Norbert, Haenel, Mathias, Neubauer, Andreas, Kneba, Michael, Merli, Francesco, Tucci, Alessandra, Brown, Peter de Nully, Federico, Massimo, Lengfelder, Eva, di Rocco, Alice, Trappe, Ralf, Rosenwald, Andreas, Berdel, Christian, Maisenhoelder, Martin, Shpilberg, Ofer, Amam, Josif, Christofyllakis, Konstantinos, Hartmann, Frank, Murawski, Niels, Stilgenbauer, Stephan, Nickelsen, Maike, Wulf, Gerald, Glass, Bertram, Schmitz, Norbert, Altmann, Bettina, Loeffler, Markus, Pfreundschuh, Michael, Poeschel, Viola, Held, Gerhard, Ziepert, Marita, Witzens-Harig, Mathias, Holte, Harald, Thurner, Lorenz, Borchmann, Peter, Viardot, Andreas, Soekler, Martin, Keller, Ulrich, Schmidt, Christian, Truemper, Lorenz, Mahlberg, Rolf, Marks, Reinhard, Hoeffkes, Heinz-Gert, Metzner, Bernd, Dierlamm, Judith, Frickhofen, Norbert, Haenel, Mathias, Neubauer, Andreas, Kneba, Michael, Merli, Francesco, Tucci, Alessandra, Brown, Peter de Nully, Federico, Massimo, Lengfelder, Eva, di Rocco, Alice, Trappe, Ralf, Rosenwald, Andreas, Berdel, Christian, Maisenhoelder, Martin, Shpilberg, Ofer, Amam, Josif, Christofyllakis, Konstantinos, Hartmann, Frank, Murawski, Niels, Stilgenbauer, Stephan, Nickelsen, Maike, Wulf, Gerald, Glass, Bertram, Schmitz, Norbert, Altmann, Bettina, Loeffler, Markus, and Pfreundschuh, Michael

Abstract

Background Six cycles of R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) are the standard treatment for aggressive B-cell non-Hodgkin lymphoma. In the FLYER trial, we assessed whether four cycles of CHOP plus six applications of rituximab are non-inferior to six cycles of R-CHOP in a population of patients with B-cell non-Hodgkin lymphoma with favourable prognosis. Methods This two-arm, open-label, international, multicentre, prospective, randomised phase 3 non-inferiority trial was done at 138 clinical sites in Denmark, Israel, Italy, Norway, and Germany. We enrolled patients aged 18-60 years, with stage I-II disease, normal serum lactate dehydrogenase concentration, ECOG performance status 0-1, and without bulky disease (maximal tumour diameter <7.5 cm). Randomisation was computer-based and done centrally in a 1:1 ratio using the Pocock minimisation algorithm after stratification for centres, stage (I vs II), and extralymphatic sites (no vs yes). Patients were assigned to receive either six cycles of R-CHOP or four cycles of R-CHOP plus two doses of rituximab. CHOP comprised cyclophosphamide (750 mg/m(2)), doxorubicin (50 mg/m(2)), and vincristine (1.4 mg/m(2), with a maximum total dose of 2 mg), all administered intravenously on day 1, plus oral prednisone or prednisolone at the discretion of the investigator (100 mg) administered on days 1-5. Rituximab was given at a dose of 375 mg/m(2) of body surface area. Cycles were repeated every 21 days. No radiotherapy was planned except for testicular lymphoma treatment. The primary endpoint was progression-free survival after 3 years. The primary analysis was done in the intention-to-treat population. Safety was assessed in all patients who received at least one dose of assigned treatment. A non-inferiority margin of -5.5% was chosen. The trial, which is completed, was prospectively registered at ClinicalTrials.gov, NCT00278421. Findings Between Dec 2, 2005, and Oct 7, 2016, 592 patien

Published
2019

23. Leitlinie - ICD10: D45 : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen

Author

Koschmieder, Steffen, Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Schweizerische Gesellschaft Für Hämatologie, Baerlocher, Gabriela M., Petrides, Petro E., Döhner, Konstanze, Schweizerische Gesellschaft Für Medizinische Onkologie, Lengfelder, Eva, Griesshammer, Martin, Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie, and Gisslinger, Heinz

Subjects
Medizin und Gesundheit
Published
2018
Full Text
View/download PDF

24. Leitlinie - ICD-10 D47.1 : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen

Author

Koschmieder, Steffen, Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Schweizerische Gesellschaft Für Hämatologie, Baerlocher, Gabriela M., Petrides, Petro E., Döhner, Konstanze, Schweizerische Gesellschaft Für Medizinische Onkologie, Lengfelder, Eva, Griesshammer, Martin, Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie, and Gisslinger, Heinz

Subjects
Medizin und Gesundheit
Published
2018
Full Text
View/download PDF

25. Primäre Myelofibrose (PFM)

Author

Griesshammer, Martin, Baerlocher, Gabriela M., Döhner, Konstanze, Gisslinger, Heinz, Koschmieder, Steffen, Petrides, Petro E., and Lengfelder, Eva

Subjects
610 Medicine & health
Published
2018
Full Text
View/download PDF

28. Leitlinie : Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen

Author

Österreichische Gesellschaft Für Hämatologie & Medizinische Onkologie, Schweizerische Gesellschaft Für Hämatologie, Petrides, Petro E., Schweizerische Gesellschaft Für Medizinische Onkologie, Lengfelder, Eva, Griesshammer, Martin, and Deutsche Gesellschaft Für Hämatologie Und Medizinische Onkologie

Subjects
Medizin und Gesundheit
Published
2018
Full Text
View/download PDF

29. Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet

Author

Sanz, Miguel A., primary, Fenaux, Pierre, additional, Tallman, Martin S., additional, Estey, Elihu H., additional, Löwenberg, Bob, additional, Naoe, Tomoki, additional, Lengfelder, Eva, additional, Döhner, Hartmut, additional, Burnett, Alan K., additional, Chen, Sai-Juan, additional, Mathews, Vikram, additional, Iland, Harry, additional, Rego, Eduardo, additional, Kantarjian, Hagop, additional, Adès, Lionel, additional, Avvisati, Giuseppe, additional, Montesinos, Pau, additional, Platzbecker, Uwe, additional, Ravandi, Farhad, additional, Russell, Nigel H., additional, and Lo-Coco, Francesco, additional

Published
2019
Full Text
View/download PDF

30. Reduction of Chemotherapy in Aggressive Non-Hodgkin's Lymphoma with Favorable Prognosis

Author

Poeschel, Viola, primary, Held, Gerhard, additional, Ziepert, Marita, additional, Witzens-Harig, Mathias, additional, Holte, Harald, additional, Thurner, Lorenz, additional, Borchmann, Peter, additional, Viardot, Andreas, additional, Soekler, Martin, additional, Keller, Ulrich, additional, Schmidt, Christian, additional, Trümper, Lorenz, additional, Mahlberg, Rolf, additional, Marks, Reinhard, additional, Hoeffkes, Heinz-Gert, additional, Metzner, Bernd, additional, Dierlamm, Judith, additional, Frickhofen, Norbert, additional, Hänel, Mathias, additional, Neubauer, Andreas, additional, Kneba, Michael, additional, Merli, Francesco, additional, Tucci, Alessandra, additional, Brown, Peter de Nully, additional, Federico, Massimo, additional, Lengfelder, Eva, additional, Rocco, Alice di, additional, Trappe, Ralf, additional, Rosenwald, Andreas, additional, Berdel, Christian, additional, Maisenhölder, Martin, additional, Shpilberg, Ofer, additional, Amam, Josif, additional, Christofyllakis, Konstantinos, additional, Hartmann, Frank, additional, Murawski, Niels, additional, Stilgenbauer, Stephan, additional, Schmitz, Norbert, additional, Altmann, Bettina, additional, Loeffler, Markus, additional, Pfreundschuh, Michael, additional, and Investigators, FLYER Trial, additional

Published
2019
Full Text
View/download PDF

31. Radiotherapy (RT) to bulky (B) and extralymphatic (E) disease in combination with 6xR-CHOP-14 or R-CHOP-21 in young good-prognosis DLBCL patients: Results of the 2x2 randomized UNFOLDER trial of the DSHNHL/GLA.

Author

Pfreundschuh, Michael, Murawski, Niels, Ziepert, Marita, Altmann, Bettina, Dreyling, Martin H., Borchmann, Peter, Luminari, Stefano, Witzens-Harig, Mathias, Dierlamm, Judith, Haenel, Mathias, Truemper, Lorenz, Metzner, Bernd, Lengfelder, Eva, Keller, Ulrich B., Ruebe, Christian, Berdel, Christian, Schmitz, Norbert, Held, Gerhard, Poeschel, Viola, Pfreundschuh, Michael, Murawski, Niels, Ziepert, Marita, Altmann, Bettina, Dreyling, Martin H., Borchmann, Peter, Luminari, Stefano, Witzens-Harig, Mathias, Dierlamm, Judith, Haenel, Mathias, Truemper, Lorenz, Metzner, Bernd, Lengfelder, Eva, Keller, Ulrich B., Ruebe, Christian, Berdel, Christian, Schmitz, Norbert, Held, Gerhard, and Poeschel, Viola

Published
2018

32. Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus standard double induction in acute myeloid leukemia-a phase 3 study

Author

Braess, Jan, Amler, Susanne, Kreuzer, Karl-Anton, Spiekermann, Karsten, Lindemann, Hans Walter, Lengfelder, Eva, Graeven, Ullrich, Staib, Peter, Ludwig, Wolf-Dieter, Biersack, Harald, Ko, Yon-Dschun, Uppenkamp, Michael J., De Wit, Maike, Korsten, Stefan, Peceny, Rudolf, Gaska, Tobias, Schiel, Xaver, Behringer, Dirk M., Kiehl, Michael G., Zinngrebe, Bettina, Meckenstock, Gerald, Roemer, Eva, Medgenberg, Dirk, Spaeth-Schwalbe, Ernst, Massenkeil, Gero, Hindahl, Heidrun, Schwerdtfeger, Rainer, Trenn, Guido, Sauerland, Cristina, Koch, Raphael, Lablans, Martin, Faldum, Andreas, Goerlich, Dennis, Bohlander, Stefan K., Schneider, Stephanie, Dufour, Annika, Buske, Christian, Fiegl, Michael, Subklewe, Marion, Braess, Birgit, Unterhalt, Michael, Baumgartner, Anja, Woermann, Bernhard, Beelen, Dietrich, Hiddemann, Wolfgang, Braess, Jan, Amler, Susanne, Kreuzer, Karl-Anton, Spiekermann, Karsten, Lindemann, Hans Walter, Lengfelder, Eva, Graeven, Ullrich, Staib, Peter, Ludwig, Wolf-Dieter, Biersack, Harald, Ko, Yon-Dschun, Uppenkamp, Michael J., De Wit, Maike, Korsten, Stefan, Peceny, Rudolf, Gaska, Tobias, Schiel, Xaver, Behringer, Dirk M., Kiehl, Michael G., Zinngrebe, Bettina, Meckenstock, Gerald, Roemer, Eva, Medgenberg, Dirk, Spaeth-Schwalbe, Ernst, Massenkeil, Gero, Hindahl, Heidrun, Schwerdtfeger, Rainer, Trenn, Guido, Sauerland, Cristina, Koch, Raphael, Lablans, Martin, Faldum, Andreas, Goerlich, Dennis, Bohlander, Stefan K., Schneider, Stephanie, Dufour, Annika, Buske, Christian, Fiegl, Michael, Subklewe, Marion, Braess, Birgit, Unterhalt, Michael, Baumgartner, Anja, Woermann, Bernhard, Beelen, Dietrich, and Hiddemann, Wolfgang

Abstract

Dose-dense induction with the S-HAM regimen was compared to standard double induction therapy in adult patients with newly diagnosed acute myeloid leukemia. Patients were centrally randomized (1:1) between S-HAM (2nd chemotherapy cycle starting on day 8 - dose-dense) and double induction with TAD-HAM or HAM(-HAM) (2nd cycle starting on day 21 - standard). 387 evaluable patients were randomly assigned to S-HAM (N - 203) and to standard double induction (N - 184). The primary endpoint overall response rate (ORR) consisting of complete remission (CR) and incomplete remission (CRi) was not significantly different (P = 0.202) between S-HAM (77%) and double induction (72%). The median overall survival was 35 months after S-HAM and 25 months after double induction (P = 0.323). Duration of critical leukopenia was significantly reduced after S-HAM (median 29 days) versus double induction (median 44 days)-P < 0.001. This translated into a significantly shortened duration of hospitalization after S-HAM (median 37 days) as compared to standard induction (median 49 days)-P < 0.001. In conclusion, dose-dense induction therapy with the S-HAM regimen shows favorable trends but no significant differences in ORR and OS compared to standard double induction. S-HAM significantly shortens critical leukopenia and the duration of hospitalization by 2 weeks.

Published
2018

33. Characteristics and Outcome of Older Patients with Acute Promyelocytic Leukemia Front-Line Treated with or without Arsenic Trioxide — an International Collaborative Study

Author

Kayser, Sabine, primary, Rahmé, Ramy, additional, Martínez-Cuadron, David, additional, Ghiaur, Gabriel, additional, Thomas, Xavier, additional, Sobas, Marta, additional, Guerci Bresler, Agnes, additional, Brunet, Salut, additional, Pigneux, Arnaud, additional, Gil, Cristina, additional, Raffoux, Emmanuel, additional, Tormo, Mar, additional, Vey, Norbert, additional, de la Serna, Javier, additional, Salamero, Olga, additional, Lengfelder, Eva, additional, Levis, Mark J., additional, Fenaux, Pierre, additional, Sanz, Miguel A., additional, Schlenk, Richard F., additional, Platzbecker, Uwe, additional, Ades, Lionel, additional, and Montesinos, Pau, additional

Published
2018
Full Text
View/download PDF

34. Prognostic value of end-of-induction PET response after first-line immunochemotherapy for follicular lymphoma (GALLIUM): secondary analysis of a randomised, phase 3 trial

Author

Trotman, Judith, primary, Barrington, Sally F, additional, Belada, David, additional, Meignan, Michel, additional, MacEwan, Robert, additional, Owen, Carolyn, additional, Ptáčník, Václav, additional, Rosta, András, additional, Fingerle-Rowson, Günter R, additional, Zhu, Jiawen, additional, Nielsen, Tina, additional, Sahin, Deniz, additional, Hiddemann, Wolfgang, additional, Marcus, Robert E, additional, Davies, Andrew, additional, Hertzberg, Mark, additional, Grigg, Andrew, additional, Cannell, Paul, additional, Quach, Hang, additional, Opat, Stephen, additional, Tam, Constantine, additional, Marlton, Paula, additional, Janssens, Ann, additional, Offner, Fritz, additional, Van eygen, Koen, additional, Sangha, Randeep, additional, Mckay, Pam, additional, Wilson, Jonathan, additional, Van Der Jagt, Richard, additional, Roitman, Daryl, additional, Trneny, Marek, additional, Mayer, Jiri, additional, Le Du, Katell, additional, Solal-Celigny, Philippe, additional, Cartron, Guillaume, additional, Foussard, Charles, additional, Frickhofen, Norbert, additional, Schmidt, Peter, additional, Graeven, Ullrich, additional, Gaska, Tobias, additional, Schlag, Rudolf, additional, Sökler, Martin, additional, Prange-Krex, Gabriele, additional, Florschütz, Axel, additional, Lindemann, Hans-Walter, additional, Schimmelpfennig, Christoph, additional, Tonndorf, Solveig, additional, Hänel, Mathias, additional, Hess, Georg, additional, Schalk, Enrico, additional, Hütten, Heiko, additional, Doelken, Gottfried, additional, Pfreundschuh, Michael, additional, Keller, Ulrich, additional, Herold, Michael, additional, Forstpointner, Roswitha, additional, Vehling-Kaiser, Ursula, additional, Hoffmann, Martin, additional, Borbenyi, Zita, additional, Udvardy, Miklos, additional, Demeter, Judit, additional, Rambaldi, Alessandro, additional, Morra, Enrica, additional, Massimo, Federico, additional, Majolino, Ignazio, additional, Balzarotti, Monica, additional, Semenzato, Gianpietro, additional, Canales Albendea, Miguel Angel, additional, Peñalver Parraga, Francisco Javier, additional, Soler Campos, Alfonso, additional, Sancho Cia, Juan Manuel, additional, Marquez Navarro, Jose Antonio, additional, Grande Garcia, Carlos, additional, Nilsson-Ehle, Herman, additional, Mccarthy, Helen, additional, Pocock, Chris, additional, Sadullah, Shalal, additional, Malladi, Ram, additional, Radford, John, additional, Kanfer, Ed, additional, Kruger, Anton, additional, Culligan, Dominic, additional, Dyer, Martin, additional, Pettengell, Ruth, additional, Seymour, John, additional, Gribben, John, additional, Al-Ismail, Saad, additional, Al-Refaie, Faris, additional, Blesing, Norbert, additional, Macnamara, Christopher, additional, O'callaghan, Ann, additional, Haynes, Andrew, additional, Follows, George, additional, Johnson, Roderick, additional, Cunningham, David, additional, Bowles, Kristian, additional, Collins, Graham, additional, Gallop-Evans, Eve, additional, Robinson, Stephen, additional, Subash, Chezhian, additional, Bailey, James, additional, Holden, Viran, additional, Neidhart, Jeffrey, additional, De Oliveira, Moacyr, additional, Tezcan, Haluk, additional, Kim, Kevin, additional, Kambhampati, Suman, additional, Lanier, Keith, additional, Mcclean, John, additional, Tobinai, Kensei, additional, Hatake, Kiyohiko, additional, Ogura, Michinori, additional, Uchida, Toshiki, additional, Ando, Kiyoshi, additional, Kinoshita, Tomohiro, additional, Höhler, Thomas, additional, Stauder, Heribert, additional, Kirsch, Andreas, additional, Koenigsmann, Michael, additional, Kremers, Stephan, additional, Illmer, Thomas, additional, Witzens-Harig, Mathias, additional, La Roseé, Paul, additional, Dürig, Jan, additional, Kneba, Michael, additional, Hensel, Manfred, additional, Fuxius, Stefan, additional, Bergmann, Lothar, additional, Hübel, Kai, additional, Buske, Christian, additional, Marks, Reinhard, additional, Wulf, Gerald, additional, Lerchenmueller, Christian, additional, Schmits, Rudolf, additional, Reinwald, Mark, additional, Lengfelder, Eva, additional, Scott, Fiona, additional, Chou, Takaaki, additional, Taniwaki, Masafumi, additional, Yoshida, Isao, additional, Ishizawa, Kenichi, additional, Uike, Naokuni, additional, Uoshima, Nobuhiko, additional, Kamitsuji, Yuri, additional, Iida, Shinsuke, additional, Ohmine, Ken, additional, Nosaka, Kisato, additional, Ide, Kazuhiko, additional, Ishikawa, Takayuki, additional, Desjardins, Pierre, additional, Finn, Nicholas, additional, Zhu, Jun, additional, Li, Wei, additional, Yu, Li, additional, Ren, Hanyun, additional, Shi, Yuan Kai, additional, Wu, Gang, additional, Hong, Xiaonan, additional, Zhang, Qingyuan, additional, Feng, Jifeng, additional, Zhan, Rong, additional, Lin, Tongyu, additional, Leppa, Sirpa, additional, Costello, Regis, additional, Tempescul, Adrian, additional, Sanhes, Laurence, additional, Tournilhac, Olivier, additional, Kirchen, Heinz, additional, Hebart, Holger, additional, Weide, Rudolf, additional, Jentsch-Ullrich, Kathleen, additional, Avivi, Irit, additional, Nagler, Arnon, additional, Gurion, Ronit, additional, Shpilberg, Ofer, additional, Leoni, Pietro, additional, Baldini, Luca, additional, Samoylova, Olga, additional, Myasnikov, Alexandr, additional, Tan, Tran-Der, additional, Chang, Hung, additional, Kumagai, Kyoya, additional, Tsukamoto, Norifumi, additional, Tsukasaki, Kunihiro, additional, Beatty, Patrick, additional, Usui, Noriko, additional, Izutsu, Koji, additional, Murayama, Tohru, additional, Ichinohe, Tatsuo, additional, Kubo, Kohmei, additional, Ishida, Fumihiro, additional, Beck, J. Thaddeus, additional, Griesinger, Frank, additional, Osmanov, Dzhelil, additional, Dakhil, Shaker, additional, Clavert, Aline, additional, Maruyama, Dai, additional, Terui, Yasuhito, additional, Yamamoto, Kazuhito, additional, Eigendorff, Ekkehard, additional, Kobayashi, Tsutomu, additional, Ichikawa, Satoshi, additional, Choi, Ilseung, additional, Wada, Katsuya, additional, Kikukawa, Yoshitaka, additional, Matsuoka, Masao, additional, Yoshino, Takayuki, additional, and Minami, Yosuke, additional

Published
2018
Full Text
View/download PDF

35. Radiotherapy (RT) to bulky (B) and extralymphatic (E) disease in combination with 6xR-CHOP-14 or R-CHOP-21 in young good-prognosis DLBCL patients: Results of the 2x2 randomized UNFOLDER trial of the DSHNHL/GLA.

Author

Pfreundschuh, Michael, primary, Murawski, Niels, additional, Ziepert, Marita, additional, Altmann, Bettina, additional, Dreyling, Martin H., additional, Borchmann, Peter, additional, Luminari, Stefano, additional, Witzens-Harig, Mathias, additional, Dierlamm, Judith, additional, Haenel, Mathias, additional, Truemper, Lorenz, additional, Metzner, Bernd, additional, Lengfelder, Eva, additional, Keller, Ulrich B., additional, Ruebe, Christian, additional, Berdel, Christian, additional, Schmitz, Norbert, additional, Held, Gerhard, additional, and Poeschel, Viola, additional

Published
2018
Full Text
View/download PDF

38. Validation of a Molecular Risk Score for Prognosis of Patients with Acute Promyelocytic Leukemia

Author

Hecht, Anna, primary, Doll, Seraphina, additional, Schaarschmidt, Heidi, additional, Nowak, Daniel, additional, Nowak, Verena, additional, Obländer, Julia, additional, Xanthopoulos, Christina, additional, Lengfelder, Eva, additional, Röllig, Christoph, additional, Ehninger, Gerhard, additional, Hofmann, Wolf-Karsten, additional, and Platzbecker, Uwe, additional

Published
2016
Full Text
View/download PDF

39. Real Life Experience with ATRA-Arsenic Trioxide Based Regimen in Acute Promyelocytic Leukemia - Updated Results of the Prospective German Intergroup Napoleon Registry

Author

Platzbecker, Uwe, primary, Lengfelder, Eva, additional, Goetze, Katharina S, additional, Röllig, Christoph, additional, Kramer, Michael, additional, Sauer, Michaela, additional, Albers, Nadine, additional, Heuser, Michael, additional, Link, Hartmut, additional, Schäfer-Eckart, Kerstin, additional, Martin, Sonja, additional, Krause, Stefan W., additional, Hänel, Mathias, additional, Bochtler, Tilmann, additional, Jakob, Andreas, additional, Reichle, Albrecht, additional, Biersack, Harald, additional, Baldus, Claudia D., additional, Goerner, Martin, additional, Basara, Nadezda, additional, Mezger, Joerg, additional, Naumann, Ralph, additional, Kuerschner, Dorit, additional, de Wit, Maike, additional, Nolte, Florian, additional, Ringhoffer, Mark, additional, Tischler, Hans-Joachim, additional, Greiner, Jochen, additional, Kremers, Stephan, additional, Machherndl-Spandl, Sigrid, additional, Koller, Elisabeth, additional, Wattad, Mohammad Amen, additional, Aschauer, Gregor, additional, Radsak, Markus, additional, Kubin, Thomas, additional, Salih, Helmut, additional, Heits, Frank, additional, Wolf, Dominik, additional, Thiede, Christian, additional, Serve, Hubert, additional, Duehrsen, Ulrich, additional, Hochhaus, Andreas, additional, Brümmendorf, Tim H., additional, Bornhäuser, Martin, additional, Döhner, Hartmut, additional, Ehninger, Gerhard, additional, and Schlenk, Richard F., additional

Published
2016
Full Text
View/download PDF

40. Comparison of Treatment Strategies in Patients over 60 Years with AML: Final Analysis of a Prospective Randomized German AML Intergroup Study

Author

Niederwieser, Dietger, primary, Hoffmann, Verena Sophia, additional, Pfirrmann, Markus, additional, Al-Ali, Haifa Kathrin, additional, Schwind, Sebastian, additional, Vucinic, Vladan, additional, Krahl, Rainer, additional, Kahl, Christoph, additional, Wolf, Hans-Heinrich, additional, Kreibich, Ute, additional, Hähling, Detlef, additional, Hegenbart, Ute, additional, Hirt, Carsten, additional, Peter, Norma, additional, Florschuetz, Axel, additional, Reifenrath, Kolja, additional, Schulze, Antje, additional, Zojer, Niklas, additional, Scholl, Sebastian, additional, Junghanss, Christian, additional, Pönisch, Wolfram, additional, Heyn, Simone, additional, Sayer, Herbert G., additional, Hochhaus, Andreas, additional, Heinicke, Thomas, additional, Fischer, Thomas, additional, Krämer, Alwin, additional, Dreger, Peter, additional, Maschmeyer, Georg, additional, Krug, Utz, additional, Sauerland, Maria Christina, additional, Heinecke, Achim, additional, Hehlmann, Rüdiger, additional, Lengfelder, Eva, additional, Hiddemann, Wolfgang, additional, Serve, Hubert, additional, Müller-Tidow, Carsten, additional, Berdel, Wolfgang E, additional, and Büchner, Thomas, additional

Published
2016
Full Text
View/download PDF

41. Publisher Correction: Outcome of older (≥70 years) APL patients frontline treated with or without arsenic trioxide—an International Collaborative Study

Author

Kayser, Sabine, Rahmé, Ramy, Martínez-Cuadrón, David, Ghiaur, Gabriel, Thomas, Xavier, Sobas, Marta, Guerci-Bresler, Agnes, Garrido, Ana, Pigneux, Arnaud, Gil, Cristina, Raffoux, Emmanuel, Tormo, Mar, Vey, Norbert, de la Serna, Javier, Salamero, Olga, Lengfelder, Eva, Levis, Mark J., Fenaux, Pierre, Sanz, Miguel A., Platzbecker, Uwe, Schlenk, Richard F., Adès, Lionel, and Montesinos, Pau

Published
2024
Full Text
View/download PDF

44. Frontline therapy of acute promyelocytic leukemia: Randomized comparison of ATRA and intensified chemotherapy versus ATRA and anthracyclines.

Author

for the German Acute Myeloid Leukemia Cooperative Group (AMLCG), Lengfelder, Eva, Nowak, Daniel, Hecht, Anna, Hofmann, Wolf‐Karsten, Schiel, Xaver, Flasshove, Michael, Wörmann, Bernhard, Görlich, Dennis, Bormann, Eike, Sauerland, Cristina, Spiekermann, Karsten, Schneider, Stephanie, Hiddemann, Wolfgang, Haferlach, Claudia, Schnittger, Susanne, Krug, Utz, Schliemann, Christoph, Berdel, Wolfgang E., and Büchner, Thomas

Subjects
*ACUTE promyelocytic leukemia, *TREATMENT of acute promyelocytic leukemia, *CYTARABINE, *TRETINOIN, *ANTHRACYCLINES, *PATIENTS, *THERAPEUTICS
Abstract

Abstract: Objectives: Randomized comparison of two treatment strategies in frontline therapy of acute promyelocytic leukemia (APL): all‐trans retinoic acid (ATRA) and double induction intensified by high‐dose cytosine arabinoside (HD ara‐C) (German AMLCG) and therapy with ATRA and anthracyclines (Spanish PETHEMA, LPA99). Patients and results: Eighty of 87 adult patients with genetically confirmed APL of all risk groups were eligible. The outcome of both arms was similar: AMLCG vs PETHEMA: hematological complete remission 87% vs 83%, early death 13% vs 17% (P = .76), overall survival, event‐free survival, leukemia‐free survival, cumulative incidence of relapse at 6 years 75% vs 78% (P = .92); 75% vs 68% (P = .29); 86% vs 81% (P = .28); and 0% vs 12% (P = .04, no relapse vs four relapses), respectively. The median time to achieve molecular remission (RT‐PCR negativity of PML‐RARA) was 60 days in both arms (P = .12). The AMLCG regimen was associated with a longer duration of neutropenia (P = .02) and a higher rate of WHO grade ≥3 infections. Conclusions: The small number of patients limits the reliability of conclusions. With these restrictions, the outcomes of both approaches were similar and show the limitations of ATRA and chemotherapy. The HD ara‐C–containing regimen was associated with a lower relapse rate in high‐risk APL. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

45. Radiation and Dose‐densification of R‐CHOP in Aggressive B‐cell Lymphoma With Intermediate Prognosis: The UNFOLDER Study.

Author

Thurner, Lorenz, Ziepert, Marita, Berdel, Christian, Schmidt, Christian, Borchmann, Peter, Kaddu‐Mulindwa, Dominic, Viardot, Andreas, Witzens‐Harig, Mathias, Dierlamm, Judith, Haenel, Mathias, Metzner, Bernd, Wulf, Gerald, Lengfelder, Eva, Keller, Ulrich B., Frickhofen, Norbert, Nickelsen, Maike, Gaska, Tobias, Griesinger, Frank, Mahlberg, Rolf, and Marks, Reinhard

Published
2023
Full Text
View/download PDF

46. Real Life Experience with ATRA-Arsenic Trioxide Based Regimen in Acute Promyelocytic Leukemia - Updated Results of the Prospective German Intergroup Napoleon Registry

Author

Platzbecker, Uwe, Lengfelder, Eva, Schäfer-Eckart, Kerstin, Götze, Katharina S, Heuser, Michael, Thol, Felicitas, Salih, Helmut R., Hänel, Mathias, Spiekermann, Karsten, Martin, Sonja, Machherndl-Spandl, Sigrid, Kunzmann, Volker, Jakob, Andreas, Tischler, Hans-Joachim, Niemann, Dirk, Mezger, Joerg, Bochtler, Tilmann, Krause, Stefan, Wit, Maike de, Baldus, Claudia D., Greil, Richard, Greiner, Jochen, Ringhoffer, Mark, Radsak, Markus, Wattad, Mohammed Amen, Schmiegel, Wolff, Koller, Elisabeth, Heits, Frank, Reichle, Albrecht, Kremers, Stephan, Hochhaus, Andreas, Basara, Nadezda, Wolf, Dominik, Goerner, Martin, Schaich, Markus, Biersack, Harald, Kirchen, Heinz, Kubin, Thomas, Aschauer, Gregor, Hesse, Tanja, Link, Hartmut, Duerk, Heinz, Kuerschner, Dorit, Fiedler, Walter, Hertenstein, Bernd, Puttrich, Martin, Kramer, Michael, Sauer, Michaela, Hiddemann, Wolfgang, Duehrsen, Ulrich, Serve, Hubert, Thiede, Christian, Ganser, Arnold, Brummendorf, Tim H., Dohner, Konstanze, Bornhäuser, Martin, Schlenk, Richard F., Rollig, Christoph, Döhner, Hartmut, Ehninger, Gerhard, and Paschka, Peter

Published
2017
Full Text
View/download PDF

47. Prognostic importance of expression of the Wilms’ tumor 1 gene in newly diagnosed acute promyelocytic leukemia

Author

Hecht, Anna, primary, Nolte, Florian, additional, Nowak, Daniel, additional, Nowak, Verena, additional, Reinwald, Mark, additional, Hanfstein, Benjamin, additional, Faldum, Andreas, additional, Büchner, Thomas, additional, Spiekermann, Karsten, additional, Sauerland, Cristina, additional, Weiss, Christel, additional, Hofmann, Wolf-Karsten, additional, and Lengfelder, Eva, additional

Published
2015
Full Text
View/download PDF

48. An Optimized Risk Stratification Model in Acute Promyelocytic Leukemia Identifies Patients with an Exceptionally Good Prognosis Regarding the Incidence of Relapse

Author

Hecht, Anna, primary, Nowak, Daniel, additional, Nowak, Verena, additional, Hanfstein, Benjamin, additional, Büchner, Thomas, additional, Spiekermann, Karsten, additional, Weiss, Christel, additional, Hofmann, Wolf-Karsten, additional, Lengfelder, Eva, additional, and Nolte, Florian, additional

Published
2014
Full Text
View/download PDF

49. Next Generation RNA Sequencing of Acute Promyelocytic Leukemia (APL) Identifies Novel Long Non Coding RNAs Including New Variants of MIR181A1HG That Are Differentially Expressed during Myeloid Differentiation

Author

Lammer, Frederic, primary, Klaumuenzer, Marion, additional, Mossner, Maximilian, additional, Jann, Johann Christoph, additional, Hecht, Anna, additional, Nowak, Verena, additional, Fey, Stephanie, additional, Oblaender, Julia, additional, Pressler, Jovita, additional, Lengfelder, Eva, additional, Hofmann, Wolf-Karsten, additional, and Nowak, Daniel, additional

Published
2014
Full Text
View/download PDF

50. Different Impact of Expression Levels of IGFBP2and IGFBP7on Survival and Relapse Rate in Acute Promyelocytic Leukemia

Author

Hecht, Anna, Nowak, Daniel, Nolte, Florian, Nowak, Verena, Oblaender, Julia, Buechner, Thomas, Spiekermann, Karsten, Hofmann, Wolf-Karsten, and Lengfelder, Eva

Abstract

Introduction: Insulin-like growth factor binding proteins (IGFBP) are carriers of insulin-like growth factors (IGFs). They prolong their half-life and modulate their availability and activity. The IGF-signaling system has been shown to have an important role in various solid cancers and hematologic malignancies. High levels of IGFBP2and IGFBP7have been associated with chemoresistance, relapse and inferior survival in different leukemias. Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML), which has been reported to have increased expression of IGFBP2. However, there is no data on its impact on prognosis. In addition, no data exist on IGFBP7in APL. The aim of this study was to elucidate the influence on prognosis of both candidate genes in APL patients.

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results