337 results on '"Levings, Megan K."'
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2. Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice
3. SARS-CoV-2 Variants Omicron BA.4/5 and XBB.1.5 Significantly Escape T Cell Recognition in Solid-organ Transplant Recipients Vaccinated Against the Ancestral Strain
4. Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation
5. Human A2-CAR T Cells Reject HLA-A2+ Human Islets Transplanted Into Mice Without Inducing Graft-Versus-Host Disease
6. PHLPP Signaling in Immune Cells
7. Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation
8. CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation
9. Interactions between islets and regulatory immune cells in health and type 1 diabetes
10. Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers
11. Recurrent Clostridioides difficile Infection Is Associated With Impaired T Helper Type 17 Immunity to C difficile Toxin B
12. 216.6: Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation
13. 213.2: Preliminary Results of the First Clinical Trial to Prevent Graft Rejection in Heart Transplant Children Employing a Cellular Therapy With Autologous Treg Obtained From Thymic Tissue (thyTreg)
14. Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection.
15. Adaptive immune responses to two-dose COVID-19 vaccine series in healthy Canadian adults ≥ 50 years: a prospective, observational cohort study.
16. Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients
17. Analysis of Flagellin-Specific Adaptive Immunity Reveals Links to Dysbiosis in Patients With Inflammatory Bowel Disease
18. 1165. Longitudinal Evaluation of SARS-CoV-2 Antibody Response Using Dried Blood Spot Samples Following Vaccination with Three and Four Doses of mRNA-1273, BNT162b2 and/or ChAdOx1-S in Adults Aged 50 and Above: Interim Analysis from the PREVENT-COVID Study
19. First-in-human therapy with Treg produced from thymic tissue (thyTreg) in a heart transplant infant
20. Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection
21. Tregs integrate native and CAR-mediated costimulatory signals for control of allograft rejection
22. mRNA vaccines take on immune tolerance
23. Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol
24. Transduction of Human T Cell Subsets with Lentivirus
25. A germline heterozygous dominant negativeIKZF2variant causing syndromic primary immune regulatory disorder and ICHAD
26. 3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
27. Adaptive immune responses to two-dose COVID-19 vaccine series in healthy Canadian adults > 50 years: a prospective, observational cohort study
28. Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes in mice
29. Alleviating graft-versus-host disease by directing regulatory T cells to the gut … It is all about location, location, location
30. Eras of designer Tregs: Harnessing synthetic biology for immune suppression
31. CD4+ T Regulatory Cells and Modulation of Undesired Immune Responses
32. Engineering therapeutic T cells to suppress alloimmune responses using TCRs, CARs, or BARs
33. Cancer immunotherapies repurposed for use in autoimmunity
34. CAR Tregs protect alloimmune islets against autoimmune destruction
35. Sex biased human thymic architecture guides T cell development through spatially defined niches
36. Ustekinumab for type 1 diabetes in adolescents: a multicenter, double-blind, randomized phase 2 trial
37. Antigen-specific regulatory T cells: are police CARs the answer?
38. “FIRST-IN-HUMAN” CLINICAL TRIAL EMPLOYING ADOPTIVE TRANSFER OF AUTOLOGOUS THYMUS-DERIVED TREG CELLS (THYTREG) TO PREVENT GRAFT REJECTION IN HEART-TRANSPLANTED CHILDREN
39. Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion
40. Targeting regulatory T cell metabolism in disease: novel therapeutic opportunities
41. Strategies for optimizing CITE-seq for human islets and other tissues
42. T cell activation induced marker assays in health and disease
43. Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes
44. Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease
45. Flagellin-specific human CAR Tregs for immune regulation in IBD
46. Fecal microbiota transplant treatment for recurrent Clostridioides difficile infection enhances adaptive immunity to TcdB
47. Taking regulatory T-cell therapy one step further
48. Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis
49. Manufacturing next-generation regulatory T-cell therapies
50. Integration of exogenous and endogenous co-stimulatory signals by CAR-Tregs
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