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The citrus cultivar 'Local Juhong', which has historically been used as a traditional Chinese medicinal material, originated in Yuanjiang County, Hunan Province.Its parental type and genetic background are indistinct as of yet. Morphological observation shows that 'Local Juhong' has a slight oblateness in fruit shape, a relatively smooth pericarp, a fine and slightly raised oil vacuole, and an inward concave at the blossom end. The tree form and fruit and leaf morphology of 'Local Juhong' are similar to those of 'Huangpi' sour orange. To reveal the genetic background of 'Local Juhong', 21 citrus accessions were evaluated using nuclear and chloroplast SSR markers and whole-genome SNP information. 'Local Juhong' was grouped with mandarins and sub-grouped with 'Miyagawa Wase' and 'Yanxi Wanlu' in a nuclear SSR analysis, which indicated that its pollen parent might be mandarins. It was closely clustered with orange and pummelo in the chloroplast SSR analysis. The genomic sequence similarity rate of 'Local Juhong' with mandarin and pummelo heterozygosity was 70.88%; the main part was the heterozygosity, except for the unknown (19.66%), mandarin (8.73%), and pummelo (3.9%) parts. Thus, 'Local Juhong' may be an F1 hybrid with pummelo as the female parent and mandarin as the male parent, sharing sisterhood with 'Huangpi' sour orange. [ABSTRACT FROM AUTHOR]

A compact all-fiber pulsed coherent Doppler lidar (PCDL) for boundary layer wind measurement was developed by the Institute of Oceanographic Instrumentation, Qilu University of Technology (Shandong Academy of Sciences). It has been deployed at Zhongshan Station (69.4° S, 76.4° E) during the 2020 austral summer season by the 36th Chinese National Antarctic Research Expedition (CHINARE) and started routine observation in January 2020. This system, based on the 1550 nm all-fiber components, employs a 100 mm telescope with a long focal length of 632.6 mm to emit and collect laser pulses. It provides the ability to measure vertically resolved wind fields with a spatial resolution of 30 m and a temporal resolution of 1 min; the maximum detection range is up to 1.5 km in Antarctica. Wind speed and direction inversion methods were introduced subsequently. Preliminary measurement results of wind profiles indicate that this Doppler lidar can be operated successfully in Antarctica. The synchronous observations between the lidar, anemometer, and radiosondes at Zhongshan station are presented and have good consistency with each other. The comparison results between the lidar and anemometer indicate a root mean square deviation (RMSD) of 0.98 m s−1 and 10.55° for wind speed and direction, respectively. The lidar continuous observations of wind profiles provide an opportunity to study the spatiotemporal variation of Antarctic wind with high resolutions, which is useful for further understanding of the atmosphere in Antarctic regions. [ABSTRACT FROM AUTHOR]

The continued increase in greenhouse gas emissions as a result of unprecedented eutrophication has resulted in a rising trend of red tides in the sea, which may be responsible for ecological degradation in the surrounding environment. Studies rarely investigate the accurate concentration of seawater eutrophication substances in offshore aquaculture areas, which may lead to the exacerbated pollution of inshore aquaculture. We examined whether offshore seawater quality monitoring can be effectively performed through unmanned aerial vehicles' (UAVs) airborne hyperspectral remote sensing technique at Jiaozhou Bay, a water body associated with eutrophication. We used the UAV airborne hyperspectral imager to detect and measure typical marine aquaculture areas in Jiaozhou Bay and selected the key parameters of seawater quality, chlorophyll-a (Chl-a) concentrations, and total suspended matter (TSM) concentrations as indicators of seawater eutrophication. The hyperspectral inversion model of the Jiaozhou Bay seawater (JZBZ) was established with the optimal sensitive band of parameters. Results showed that in comparison with the traditional inversion model, the inversion R2 of the Chl-a was 0.712, the RPD was 3.72, and the inversion R2 of the TSM concentration was 0.756 while the RPD was 5.83. We found that this model is more suitable for the retrieval of water color parameters in Jiaozhou Bay. Additionally, by actual measurement, it can be seen that the concentration ranges of Chl-a in the observation area are 0.380–1.74 mg/m3, and the concentration range of TSM is 12.6–131 mg/L. The results of this study indicate that the Jiaozhou Bay Water Quality Translation Model (JZBM), based on the UAV airborne hyperspectral imager, performs well in the inversion of the concentration of chlorophyll and suspended particulate matter in offshore water, which advances our understanding with a new method to assess the degree of eutrophication in coastal waters. [ABSTRACT FROM AUTHOR]

• An underwater coaxial scanning photon counting Lidar system based on two-dimensional turntable is developed. • A spatiotemporal correlation method based on instrument response function matched filtering preprocessing is proposed. • The ranging accuracy and resolution of the system are better than 1.0 cm. • An effective method are provided for high precision and high resolution 3D imaging of underwater targets. A coaxial scanning photon counting Lidar is developed to achieve three-dimensional (3D) imaging of underwater targets. A spatiotemporal correlation-based method is proposed to achieve high-precision detection, which involves preprocessing using matched filtering with the instrument response function. A single-point repeatability measurement of a planar target and a 3D image of a resolution plate are performed using the Lidar system and the signal reconstruction algorithm. The experimental results demonstrate that the ranging accuracy is better than 1.0 cm. Compared with the maximum likelihood estimation method, the proposed method exhibits higher ranging accuracy when the target distance does not change steeply. Additionally, the 3D imaging results of the target model consisting of a car and a suitcase can clearly distinguish features such as the rearview mirror, headlight, handle, and lock. The system has potential applications in underwater target identification, ocean engineering construction, underwater archaeology, and other fields requiring high-precision 3D imaging. [ABSTRACT FROM AUTHOR]

• The RUL prognosis framework combines the wavelet transform and the ConvLSTM. • Channel self-attention highlights weak but crucial features in wavelet coefficients. • Global attention improves the representation of the learned features in multiple wavelet coefficients of different channels. • Hybrid attention-based method boosts convlstm's performance in RUL prognosis. Wavelet transform, a time-frequency analysis method for evaluating non-stationary signals, can assist in representing equipment degradation over prolonged usage. However, a single wavelet basis function is challenging to apply to all periodic transient waveforms. As a result, this research suggests a hybrid attention-based multi-wavelet coefficient fusion method for evaluating the remaining useful life (RUL) of bearings. Firstly, a two-dimensional map is created by organizing the decomposed individual frequency bands after the approach employs several wavelets to get the original signal properties. Secondly, a hybrid attention-based ConvLSTM (HA-ConvLSTM) network is designed to weight wavelet coefficient channels adaptively. The learned features are used to evaluate RULs by a multi-layer perceptron. Finally, tests were run on the PHM2012 rolling bearing dataset to validate the proposed method. Overall, the suggested scheme outperforms previous comparable methods in the performance index. This approach optionally resolves the wavelet basis function matching issue for periodic transient waveforms. [ABSTRACT FROM AUTHOR]

Neuron-derived neurotrophic factor (NDNF) is a glycosylated, disulfide-bonded secretory protein that contains a fibronectin type III domain. NDNF has been identified as a neurotrophic factor; however, its role in carcinogenesis has not yet been identified. To investigate the expression and role of NDNF in carcinogenesis, the expression of NDNF in human Renal cell carcinoma (RCC) cell lines and tissues was detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blot analysis. Cell proliferation was investigated using CCK-8 and colony formation assays, and the cell invasion and immigration capacity was evaluated using the transwell assay. The results demonstrated that NDNF expression was downregulated in RCC cell lines and RCC tissues. Restoring NDNF expression significantly inhibited the proliferation, migration and invasion of RCC cells. The study also demonstrated that the inhibitory effect of NDNF on invasive ability was mediated by suppressing the epithelial-mesenchymal transition (EMT) in RCC cells. NDNF may therefore be considered an important regulator of EMT in RCC progression and may represent a novel promising target for antimetastatic therapy. [ABSTRACT FROM AUTHOR]

Objectives To evaluate the efficacy of resiniferatoxin in the treatment of patients with lifelong premature ejaculation. Methods A total of 41 outpatients (mean age 26.14 ± 4 years) with premature ejaculation completed the present study. They were randomly separated into the resiniferatoxin group and the placebo group. The resiniferatoxin group included 11 patients with redundant prepuce and 10 patients without redundant prepuce, whereas the placebo group contained 10 patients with redundant prepuce and 10 patients without. For the treatment, the glans were respectively soaked in 30 mL of resiniferatoxin with a concentration of 100 nmol/L or 10% alcohol solution for 30 min before sexual intercourse. Clinical efficacy was assessed by using the Chinese Index of Sexual Function for Premature Ejaculation-5 and the intravaginal ejaculation latency time before or 4 weeks after the treatment. The side-effects were also evaluated. Results In the resiniferatoxin group, the effective rate of patients with redundant prepuce was 63.6%, and both the intravaginal ejaculation latency time and Chinese Index of Sexual Function for Premature Ejaculation-5 significantly increased ( P < 0.05). However, the effective rate of patients without redundant prepuce was 20%, and there were no significant changes of their intravaginal ejaculation latency time and Chinese Index of Sexual Function for Premature Ejaculation-5 before and after the resiniferatoxin treatment ( P > 0.05). The total effective rate of patients treated with resiniferatoxin was 42.9%. In the placebo group, the effective rate of patients with or without redundant prepuce was 20% and 10%, respectively. The total effective rate of patients treated with placebo was 15%, and there were no significant changes of their intravaginal ejaculation latency time and Chinese Index of Sexual Function for Premature Ejaculation-5 before and after the placebo treatment ( P > 0.05). The side-effects included a slight burning sensation for the glans penis and dysuria. Conclusions These preliminary results show that resiniferatoxin might be suitable for treating patients with lifelong premature ejaculation and particularly those with redundant prepuce. [ABSTRACT FROM AUTHOR]

• 'Huarongdao Zhoupigan' is a cultivated landrace with a history of more than a hundred years. • Parentage and origination was predicted by morphological, SSR marker and genomic analyses. • 'Huarongdao Zhoupigan' may be a natural hybrid with sour orange (a sexual hybrid of pummelo and mandarin) as the seed parent and mandarin as the pollen parent. The cultivated landrace 'Huarongdao Zhoupigan' originated in China, and it has a history of more than a hundred years. It is widely cultivated for its distinctive pericarp, soft juicy pulp, slight bitter taste, and rich flavonoids and vitamin C (17.2 ± 0.08 mg•mL−1). Morphological observation shows that 'Huarongdao Zhoupigan' is mandarin-like in leaf shape, fruit flesh, easy peeling and crumpled pericarp, implying this variety may be a hybrid of orange and mandarin. To reveal the genetic background of 'Huarongdao Zhoupigan', 21 citrus accessions were evaluated using nuclear and chloroplast SSR markers and whole-genome SNP information. 'Huarongdao Zhoupigan' was grouped with mandarins and closely clustered with 'Yuanjiang Nanju' in the nuclear SSR analysis and sub-grouped with 'Goutou' sour orange, 'Dahong' sweet orange and 'Newhall' navel orange in the chloroplast SSR analysis. The genomic sequence similarity rate of 'Huarongdao Zhoupigan' with mandarin was 36.09%, with mandarin heterozygosity of 46.50%; the rough ratio of the two main parts was nearly 1:1, except for the unknown (19.11%) and pummelo (1.46%) parts. Thus, 'Huarongdao Zhoupigan' may be a natural hybrid with sour orange (a sexual hybrid of pummelo and mandarin) as the seed parent and mandarin as the pollen parent. [ABSTRACT FROM AUTHOR]

A polarized micropulse lidar (P-MPL) employing a pulsed laser at 532 nm was developed by the Institute of Oceanographic Instrumentation, Qilu University of Technology (Shandong Academy of Sciences). The optomechanical structure, technical parameters, detection principle, overlap factor calculation method, and inversion methods of the atmospheric boundary layer (ABL) depth and depolarization ratio (DR) were introduced. Continuous observations using the P-MPL were carried out at Xi'an Meteorological Bureau, and the observation data were analyzed. In this study, we gleaned much information on aerosols and clouds, including the temporal and spatial variation of aerosols and clouds, aerosol extinction coefficient, DR, and the structure of ABL were obtained by the P-MPL. The variation of aerosols and clouds before and after a short rainfall was analyzed by combining time-height-indication (THI) of range corrected signal (RCS) and DR was obtained by the P-MPL with profiles of potential temperature (PT) and relative humidity (RH) detected by GTS1 Digital Radiosonde. Then, the characteristics of tropopause cirrus cloud were discussed using the data of DR, PT, and RH. Finally, a haze process from January 1st to January 5th was studied by using aerosol extinction coefficients obtained by the P-MPL, PT, and RH profiles measured by GTS1 Digital Radiosonde and the time-varying of PM2.5 and PM10 observed by ambient air quality monitor. The source of the haze was simulated by using the NOAA HYSPLIT Trajectory Model. [ABSTRACT FROM AUTHOR]