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Your search keyword '"Long, Zhihe"' showing total 145 results
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145 results on '"Long, Zhihe"'

20. A wireless battery-free eye modulation patch for high myopia therapy.

Author

Zhong, Tianyan, Yi, Hangjin, Gou, Jiacheng, Li, Jie, Liu, Miao, Gao, Xing, Chen, Sizhu, Guan, Hongye, Liang, Shan, He, Qianxiong, Lin, Rui, Long, Zhihe, Wang, Yue, Shi, Chuang, Zhan, Yang, Zhang, Yan, Xing, Lili, Zhong, Jie, and Xue, Xinyu

Subjects
SCLERA, MYOPIA, PIEZOELECTRIC transducers, FLEXIBLE printed circuits, BLUE light, VISUAL accommodation, VITAMIN B2
Abstract

The proper axial length of the eye is crucial for achieving emmetropia. In this study, we present a wireless battery-free eye modulation patch designed to correct high myopia and prevent relapse. The patch consists of piezoelectric transducers, an electrochemical micro-actuator, a drug microneedle array, μ-LEDs, a flexible circuit, and biocompatible encapsulation. The system can be wirelessly powered and controlled using external ultrasound. The electrochemical micro-actuator plays a key role in precisely shortening the axial length by driving the posterior sclera inward. This ensures accurate scene imaging on the retina for myopia eye. The drug microneedle array delivers riboflavin to the posterior sclera, and μ-LEDs' blue light induces collagen cross-linking, reinforcing sclera strength. In vivo experiments demonstrate that the patch successfully reduces the rabbit eye's axial length by ~1217 μm and increases sclera strength by 387%. The system operates effectively within the body without the need for batteries. Here, we show that the patch offers a promising avenue for clinically treating high myopia. The proper axial length of the eye is crucial for achieving emmetropia. Here, authors introduce a wireless battery-free eye modulation patch designed to correct high myopia and prevent relapse. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Wireless Battery‐Free Peripheral Nerve Stimulation Conch for Remote Muscle Activation.

Author

Zhang, Mingwang, Yang, Guangyou, Long, Zhihe, Tang, Yong, Li, Dongming, Liang, Shan, Lin, Rui, Yang, Zhixin, Bao, Han, Xing, Lili, Xue, Xinyu, Zhan, Yang, and Xie, Yan

Subjects
NEURAL stimulation, PERIPHERAL nervous system, PIEZOELECTRICITY, SCIATIC nerve, CRYSTAL resonators
Abstract

Peripheral nerve stimulators have emerged as a crucial instrument in the realm of neurological disease, capable of modulating nerve activity through precisely targeted electrical stimulation to specific sites within the nervous system. Herein, a new wireless battery‐free peripheral nerve stimulation device for remote muscle activation is developed. The device with conch‐inspired bionic design can be wirelessly powered and controlled by a mobile phone playing audio via the piezoelectric effect. The device consists of two parts: a conch‐like signal‐intensifying piezoelectric resonator for converting acoustic wave into electrostimulation signal; and a pedestal with stimulation electrodes for transmitting the electrostimulation signal to a peripheral nerve. For remote nerve intervention, a programmed audio tone from one mobile phone can be tele‐transmitted from other phones according to the desired stimulation protocols. In‐vivo experiments in stimulating the sciatic nerve in mice showed that the device can activate muscles (e.g., 1 Hz 920 mV for 26 degree of leg movement), and the neuron‐muscle interaction has been confirmed by electromyogram (EMG). The wireless peripheral nerve stimulation conch achieves feasible remote muscle activation without batteries, and can extend the scope of self‐powered techniques for telemedicine and limb/trunk rehabilitation. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Cellphone Remote Intelligent Neuroregulation with Self-Powered Wireless Brain Probe

Author

Guan, Hongye, primary, Tang, Yong, additional, Long, Zhihe, additional, Lin, Rui, additional, Liang, Shan, additional, Zhu, Fuqiang, additional, Zhong, Tianyan, additional, Zhang, Yaming, additional, Fan, Yaowei, additional, Wang, Zhen, additional, Shi, Chuang, additional, Ma, Wanli, additional, Sun, Sheng, additional, Chen, Meihua, additional, Xing, Lili, additional, Zhang, Yan, additional, Xue, Xinyu, additional, and Zhan, Yang, additional

Published
2022
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