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Your search keyword '"Lorenzo Bandini"' showing total 3 results
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3 results on '"Lorenzo Bandini"'

1. The Impact of Rotavirus Vaccination on Discharges for Pediatric Gastroenteritis in Italy: An Eleven Year (2009–2019) Nationwide Analysis

Author

Claudia Isonne, Daniele Petrone, Martina Del Manso, Jessica Iera, Alessandra Caramia, Lorenzo Bandini, Giulia Fadda, Adriano Grossi, Valentina Baccolini, Claudio Costantino, Patrizio Pezzotti, Andrea Siddu, and Fortunato D’Ancona

Subjects
vaccination, rotavirus, rotavirus vaccine, pediatric gastroenteritis, discharges, Medicine
Abstract

In Italy, despite the documented positive effects of rotavirus (RV) vaccination on reducing the burden of RV disease, an updated national assessment of its impact on clinical outcomes is still lacking. This study aims to analyze the implementation of RV vaccination in Italy, evaluating its impact on discharges for acute pediatric gastroenteritis (AGE). A retrospective analysis, including hospital discharge records and data on vaccination coverage for children aged 0–71 months from 2009 to 2019, was conducted. We examined trends in hospital discharge standardized incidence before and after vaccine introduction using a negative binomial mixture model with fixed effects to evaluate the impact of universal vaccination. The percentage of vaccination coverage increased over the years, from

Published
2023
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3. Early Warning Systems for Emerging Profiles of Antimicrobial Resistance in Italy: A National Survey

Author

Jessica Iera, Chiara Seghieri, Lara Tavoschi, Claudia Isonne, Valentina Baccolini, Daniele Petrone, Antonella Agodi, Martina Barchitta, Luca Arnoldo, Roberta Creti, Silvia Forni, Annibale Raglio, Enrico Ricchizzi, Lorenzo Bandini, Adriano Grossi, and Fortunato D’Ancona

Subjects
antimicrobial resistance, early warning system, emerging antimicrobial resistance, surveillance, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health
Abstract

Antimicrobial resistance (AMR) national surveillance systems in Italy lack alert systems for timely detection of emerging profiles of AMR with potential relevance to public health. Furthermore, the existence of early warning systems (EWS) at subnational level is unclear. This study aims at mapping and characterizing EWS for microbiological threats available at regional level in Italy, focusing on emerging AMR, and at outlining potential barriers and facilitators to their development/implementation. To this end, a three-section, web-based survey was developed and administered to all Italian regional AMR representatives from June to August 2022. Twenty out of twenty-one regions and autonomous provinces (95.2%) responded to the survey. Among these, nine (45%) reported the implementation of EWS for microbiological threats at regional level, three (15%) reported that EWS are in the process of being developed, and eight (40%) reported that EWS are not currently available. EWS characteristics varied widely among the identified systems concerning both AMR profiles reported and data flow: the microorganisms most frequently included were extensively drug-resistant (XDR) Enterobacterales, with the lack of a dedicated regional IT platform reported in most cases. The results of this study depict a highly heterogeneous scenario and suggest that more efforts aimed at strengthening national AMR surveillance systems are needed.

Published
2023

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