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Your search keyword '"Lozano, Evelyn"' showing total 11 results
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11 results on '"Lozano, Evelyn"'

1. Erdafitinib in the Treatment of Metastatic Urothelial Carcinoma

Author

Castro-Alonso, Francisco, Beas-Lozano, Evelyn, Remolina-Bonilla, Yuly A., Flaig, Thomas W., and Bourlon, Maria T.

Subjects
Metastasis -- Drug therapy, Medical colleges, Chemotherapy, Cancer -- Drug therapy -- Chemotherapy, Health
Abstract

Platinum-based chemotherapy is the standard first-line treatment for patients with MUBC, with either cisplatin or carboplatin combinations. (1-4) In patients whose disease does not progress on chemotherapy, maintenance with avelumab [...]

Published
2023

5. Sa1632 A GROWING THREAT OF HEPATITIS A AND ASSOCIATED MORTALITY IN MEXICO - A MULTICENTER COHORT

Author

Aguirre-Villarreal, David, Beas-Lozano, Evelyn Lilian, Montes, Mario S., Jasso-Baltazar, Erick A., Fernandez-Ramirez, Alfonso J., Fierro-Angulo, Oscar Manuel, Barradas, Mauricio Castillo, Rizo-Robles, María Teresa Guadalupe, Garcia-Campos, Karenn, Prieto-Nava, José-David, Renteria, Luis Alejandro Rosales, Gonzalez-Huezo, Maria Sarai, Rivera-Chavez, José Guadalupe, Piña, Luis O., Aguirre-Valadez, Jonathan, Gonzalez-Chagolla, Alex, Ramírez-Zamudio, Lizeth Carolina, Sanchez-Avila, Juan F., and García-Juárez, Ignacio

Published
2024
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6. A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning

Author

Hafez, Alexander K., primary, Zimmerman, Amber J., additional, Papageorgiou, Grigorios, additional, Chandrasekaran, Jayapriya, additional, Amoah, Stephen K., additional, Lin, Rixing, additional, Lozano, Evelyn, additional, Pierotti, Caroline, additional, Dell’Orco, Michela, additional, Hartley, Brigham J., additional, Alural, Begüm, additional, Lalonde, Jasmin, additional, Esposito, John Matthew, additional, Berretta, Sabina, additional, Squassina, Alessio, additional, Chillotti, Caterina, additional, Voloudakis, Georgios, additional, Shao, Zhiping, additional, Fullard, John F., additional, Brennand, Kristen J., additional, Turecki, Gustavo, additional, Roussos, Panos, additional, Perlis, Roy H., additional, Haggarty, Stephen J., additional, Perrone-Bizzozero, Nora, additional, Brigman, Jonathan L., additional, and Mellios, Nikolaos, additional

Published
2022
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8. A Bi-Directional Competitive Interaction between CircHomer1 and Homer1b within the Orbitofrontal Cortex Regulates Reversal Learning

Author

Hafez, Alexander K., primary, Zimmerman, Amber J., additional, Papageorgiou, Grigorios, additional, Chandrasekaran, Jayapriya, additional, Amoah, Stephen K., additional, Lin, Rixing, additional, Lozano, Evelyn, additional, Pierotti, Caroline, additional, Dell’Orco, Michela, additional, Hartley, Brigham J., additional, Alural, Begüm, additional, Lalonde, Jasmin, additional, Esposito, John Matthew, additional, Berretta, Sabina, additional, Squassina, Alessio, additional, Chillotti, Caterina, additional, Brennand, Kristen J., additional, Turecki, Gustavo, additional, Perlis, Roy H., additional, Haggarty, Stephen J., additional, Perrone-Bizzozero, Nora, additional, Brigman, Jonathan L., additional, and Mellios, Nikolaos, additional

Published
2020
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10. A bidirectional competitive interaction between circHomer1and Homer1bwithin the orbitofrontal cortex regulates reversal learning

Author

Hafez, Alexander K., Zimmerman, Amber J., Papageorgiou, Grigorios, Chandrasekaran, Jayapriya, Amoah, Stephen K., Lin, Rixing, Lozano, Evelyn, Pierotti, Caroline, Dell’Orco, Michela, Hartley, Brigham J., Alural, Begüm, Lalonde, Jasmin, Esposito, John Matthew, Berretta, Sabina, Squassina, Alessio, Chillotti, Caterina, Voloudakis, Georgios, Shao, Zhiping, Fullard, John F., Brennand, Kristen J., Turecki, Gustavo, Roussos, Panos, Perlis, Roy H., Haggarty, Stephen J., Perrone-Bizzozero, Nora, Brigman, Jonathan L., and Mellios, Nikolaos

Abstract

Although circular RNAs (circRNAs) are enriched in the brain, their relevance for brain function and psychiatric disorders is poorly understood. Here, we show that circHomer1is inversely associated with relative HOMER1BmRNA isoform levels in both the orbitofrontal cortex (OFC) and stem-cell-derived neuronal cultures of subjects with psychiatric disorders. We further demonstrate that in vivo circHomer1knockdown (KD) within the OFC can inhibit the synaptic expression of Homer1bmRNA. Furthermore, we show that circHomer1directly binds to Homer1bmRNA and that Homer1b-specific KD increases synaptic circHomer1levels and improves OFC-mediated behavioral flexibility. Importantly, double circHomer1and Homer1b in vivoco-KD results in a complete rescue in circHomer1-associated alterations in both chance reversal learning and synaptic gene expression. Lastly, we uncover an RNA-binding protein that can directly bind to circHomer1and promote its biogenesis. Taken together, our data provide mechanistic insights into the importance of circRNAs in brain function and disease.

Published
2022
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11. Current management of cervical cancer in women living with HIV.

Author

Beas-Lozano EL, Contreras S, Donald-Jaramillo MAM, Frayde-Aguilar C, Carrillo-Vidales J, Jaime-Casas S, and Martinez-Cannon BA

Abstract

Cervical cancer is a significant global health issue, particularly in low- and middle-income countries. Women living with HIV (WLWH) are not only at higher risk of cervical cancer due to their increased susceptibility to high-risk human papillomavirus (HPV) infection and compromised immune status, but also higher mortality rates have been reported. Therefore, prevention, optimal screening, use of highly active antiretroviral therapy (HAART), and early access to treatment are of utmost importance in this population. While international guidelines for cervical cancer state no treatment differences should be made for WLWH, there is evidence that this population of patients represents a challenge in decision-making for medical oncologists, radiation oncologists, and surgical oncologists. This review summarizes the available evidence on the different treatment strategies for WLWH and invasive cervical cancer and highlights the need for special considerations in screening andprevention of cervical cancer in WLWH., Competing Interests: Declaration of Competing Interest No conflict, (Copyright © 2024 Elsevier B.V. All rights reserved.)

Published
2024
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