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The use of environmental materials such as plant extract for the synthesis of silver nanoparticles (AgNPs) offers numerous benefits of eco-friendliness and compatibility for pharmaceutical and other biomedical Applications. In this study, we used Momordica charantia leaf extract as a reducing agent for the synthesis of AgNPs. Characterization of the AgNPs was done by UV-Visible Spectroscopy, FTIR, SEM, TEM and EDX. Furthermore, we established the in vitro anticancer efficacy of these nanoparticles against the human breast cancer cell line MCF-7 using MTT assay, nuclear morphology testing, and staining. In addition to the above, the anti-bacterial effect was also tested against a range of bacterial isolates using well-diffusion method. These AgNPs also demonstrated impressive results when tested for their free-radical scavenging efficiency on the MCF-7 breast cancer cell line, indicating future potential for their use in medicine. These findings indicated the possible applicability of biosynthesized AgNPs derived from Momordica charantia L. [ABSTRACT FROM AUTHOR]

The usage of copper nanoparticles (CuNPs) is now acknowledged as a promising therapeutic agent in the detection and treatment of cancer. This study aimed to develop a sustainable method for synthesizing CuNPs using Pedalium murex L. and characterization by SEM, FTIR, XRD & UV-Vis methods. The produced CuNPs were primarily spherical and varied in shape, and the average dimension ranged between 20 and 50 nm. The aqueous fruit juice of Pedalium murex L. contained biomolecules that serve as capping and reducing agents for the production of CuNPs, according to the findings of FTIR analysis. Various assays were used to determine the fruit extract's in vitro antioxidant activity. CuNPs exhibited dose-dependent cytotoxicity and apoptosis promotion in A549 cells. The findings demonstrated that biosynthesized CuNPs using Pedalium murex L. fruit juice have anti-cancer properties and can be used in lung cancer treatment, particularly for early-stage intervention. [ABSTRACT FROM AUTHOR]