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For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips. - Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource. - Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis. - Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases. - Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases. - Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci. - PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America. - Includes regular updates online for the life of the edition. - Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

The consummate guide to cardiac pacing and defibrillator therapy in a clinical setting Designed to provide clinicians and fellows with a complete, up-to-date breakdown of current device therapies for pacing and defibrillation, Cardiac Pacing and ICDs reflects the latest developments in the device treatment of heart rhythm abnormalities. Topics ranging from essential principals to new and innovative techniques are explored in focused chapters, illustrated with full-color images, charts, and diagrams. Addressing every aspect of permanent and temporary pacing and defibrillation therapy, this invaluable resource covers patient indications, pacing mode selection, implantation and removal techniques, troubleshooting, and much more. The seventh edition has been expanded and revised to enable clear and practical understanding of the field as it exists today. Drawing upon real-world experience and cutting-edge research, it offers accessible, systematic guidance with a clinical focus, as well as a wealth of bitesize tips and tricks. Access to a new companion website provides insightful supplementary material, complete with downloadable images and video clips of key techniques. This essential book: Provides an intuitive, easy-to-navigate guide to cardiac pacing techniques and devices Explains pacing hemodynamics in practical, clinically relevant terms Features simple algorithms for mode selection and device programming Offers details of novel pacing systems and techniques, such as leadless pacemaker and His bundle pacing. Covers pacemaker timing cycles, special features, and evaluation and management of pacing system malfunctions Summarizes indications and details implantation techniques of ICDs, including transvenous and subcutaneous systems Includes best practices in MRI safety, patient consultation, and remote patient follow-up Cardiac Pacing and ICDs is an ideal resource for clinicians and fellows in cardiology and electrophysiology, those preparing for the IHRBE Examination in Devices, and any nurses, technicians, and other professionals caring for patients with implantable cardiac devices.

This book describes and assesses some of the more important difficulties and defects in the current utilization of organ substitution technology, dealing with the major ethical, legal, and public policy issues of organ substitution.

With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe's Intensive Care Medicine offers authoritative guidance to the wide variety of specialty physicians and non-physicians practicing in the adult intensive care environment. This comprehensive textbook covers both the theoretical and practical aspects of the field, and has been completely updated to provide encyclopedic, interprofessional coverage to support practitioners in every area of this complex field.

Kucers'The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference.Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.

This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.​

Heart failure is epidemic throughout the world. A growing incidence and prevalence has resulted in a large population of individuals transitioning to advanced stages of the syndrome and requiring uniquely specialised therapies and cardiac transplantation. ^i The Oxford Textbook of Advanced Heart Failure and Cardiac Transplantation^r is a focused and comprehensive work covering this new and rapidly growing cardiovascular subspecialty. Authored by eminent international experts, it is the authoritative text on advanced heart failure and a central resource for clinicians caring for patients with this condition. By covering a range of characteristics, therapeutic challenges and practical aspects of managing patients, this book provides an in-depth source for cardiologists and other related clinicians. A strong focus on the difficult decision making needed to handle advanced heart failure cases, along with specific knowledge of epidemiology, biology and pathophysiology, creates a key tool for optimally managing these complex patients.

Your must-have bench reference for cardiac electrophysiology is now better than ever! This globally recognized gold standard text provides a complete overview of clinical EP, with in-depth, expert information that helps you deliver superior clinical outcomes. In this updated 5th Edition, you'll find all-new material on devices, techniques, trials, and much more – all designed to help you strengthen your skills in this fast-changing area and stay on the cutting edge of today's most successful cardiac EP techniques. - Expert guidance from world authorities who contribute fresh perspectives on the challenging clinical area of cardiac electrophysiology. - New focus on clinical relevance throughout, with reorganized content and 15 new chapters. - New coverage of balloons, snares, venoplasty, spinal and neural stimulation, subcutaneous ICDs and leadless pacing, non-CS lead implantation, His-bundle pacing, and much more. - New sections on cardiac anatomy and physiology and imaging of the heart, a new online chapter covering radiography of devices, and thought-provoking new information on the basic science of device implantation. - State-of-the-art guidance on pacing for spinal and neural stimulation, computer simulation and modeling, biological pacemakers, perioperative and pre-procedural management of device patients, and much more. - Greatly expanded online video library demonstrating key procedures and new technologies such as sub Q ICDs, implantation of non-coronary sinus left ventricular leads, the use of snares, and venoplasty of the subclavian and coronary sinus. - More than 60 multimedia case presentations online covering a broad range of heart rhythm scenarios. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.

For complete, authoritative coverage of every aspect of thoracic and cardiac surgery, turn to the unparalleled guidance found in Sabiston and Spencer Surgery of the Chest, 9th Edition. Now in full-color for the first time, Drs. Frank W. Sellke, Pedro J. del Nido, and Scott J. Swanson's standard-setting set is meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques performed in the operating room. With its comprehensive coverage of thoracic as well as adult and pediatric cardiac surgery, this 9th Edition is an essential resource not only for all thoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest. - Find what you need quickly with short, focused chapters divided into three major sections: Adult Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. - Benefit from the knowledge and expertise of global experts who provide a comprehensive view of the entire specialty. - Master all of the most important current knowledge and techniques in cardiac and thoracic surgery—whether for specialty board review or day-to-day surgical practice. - Visualize challenging surgical techniques and procedures and navigate the text more efficiently thanks to an all-new, full-color design. - Stay up to date with revised or all-new chapters including Critical Care for War-related Thoracic Surgery; Neuromonitoring and Neurodevelopment Outcomes in Congenital Heart Surgery; and Quality Improvement: Surgical Performance. - Keep abreast of cutting-edge topics such as endovascular stenting and cell-based therapies, as well as the latest innovations in imaging and diagnosis, minimally invasive cardiothoracic surgery, and percutaneous devices. - Sharpen your surgical skills with access to 21 procedural videos online, including 3 new videos covering Surgical Technique-VATS Sympathetic Block; Open pneumothorax; and Extent II repair of thoracoabdominal aortic aneurysm.