Search

Your search keyword '"Melis, René"' showing total 468 results
Start Over Author "Melis, René" Publication Year Range Last 10 years
468 results on '"Melis, René"'

4. Availability of Cognitive Resources in Early Life Predicts Transitions Between Cognitive States in Middle and Older Adults From Europe

Author

Lewis, Nathan A, Yoneda, Tomiko, Melis, René JF, Mroczek, Daniel K, Hofer, Scott M, and Muniz-Terrera, Graciela

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Aging, Behavioral and Social Science, Basic Behavioral and Social Science, Quality Education, Cognitive reserve, Cognitive resilience, Cognitive resources, Clinical sciences
Abstract

Background and objectivesThe existing literature highlights the importance of reading books in middle-to-older adulthood for cognitive functioning; very few studies, however, have examined the importance of childhood cognitive resources for cognitive outcomes later in life.Research design and methodsUsing data from 11 countries included in the Survey of Health, Ageing, and Retirement in Europe (SHARE) data set (N = 32,783), multistate survival models (MSMs) were fit to examine the importance of access to reading material in childhood on transitions through cognitive status categories (no cognitive impairment and impaired cognitive functioning) and death. Additionally, using the transition probabilities estimated by the MSMs, we estimated the remaining years of life without cognitive impairment and total longevity. All models were fit individually in each country, as well as within the pooled SHARE sample.ResultsAdjusting for age, sex, education, and childhood socioeconomic status, the overall pooled estimate indicated that access to more books at age 10 was associated with a decreased risk of developing cognitive impairment (adjusted hazard ratio = 0.79, confidence interval: 0.76-0.82). Access to childhood books was not associated with risk of transitioning from normal cognitive functioning to death, or from cognitive impairment to death. Total longevity was similar between participants reporting high (+1 standard deviation [SD]) and low (-1 SD) number of books in the childhood home; however, individuals with more access to childhood books lived a greater proportion of this time without cognitive impairment.Discussion and implicationsFindings suggest that access to cognitive resources in childhood is protective for cognitive aging processes in older adulthood.

Published
2023

5. Which Frail Older Patients Use Online Health Communities and Why? A Mixed Methods Process Evaluation of Use of the Health and Welfare Portal

Author

Makai, Peter, Perry, Marieke, Robben, Sarah HM, Schers, Henk, Heinen, Maud, Olde Rikkert, Marcel GM, and Melis, René JF

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundFrail older people often receive fragmented care from multiple providers. According to the literature, there is an urgent need for coordination of care. Online and eHealth tools are increasingly used to improve coordination. However, there are significant barriers to their implementation in frail older people. ObjectiveOur aim was to (1) evaluate differences in use of a personal online health community (POHC) for frail older people in relation to personal characteristics, and (2) explore barriers and facilitators for use as experienced by older people and their informal caregivers, using the case of the Health and Welfare Information Portal (ZWIP). MethodsThis is a mixed methods study. For the quantitative analysis, we used POHC usage information (2 years follow-up) and baseline characteristics of frail older people. For the qualitative analysis, we used semistructured interviews with older people and their informal caregivers. Participants were recruited from 11 family practices in the east of the Netherlands and frail older people over 70 years. The ZWIP intervention is a personal online health community for frail older people, their informal caregivers, and their providers. ZWIP was developed at the Geriatrics Department of Radboud University Medical Center. We collected data on POHC use for 2 years as well as relevant patient characteristics. Interview topics were description of use, reasons for use and non-use, and user profiles. ResultsOf 622 frail patients in the intervention group, 290 were connected to ZWIP; 79 used ZWIP regularly (at least monthly). Main predictors for use were having an informal caregiver, having problems with activities of daily living, and having a large number of providers. Family practice level predictors were being located in a village, and whether the family practitioners had previously used electronic consultation and cared for a large percentage of frail older people. From 23 interviews, main reasons for use were perceiving ZWIP to be a good, quick, and easy way of communicating with providers and the presence of active health problems. Important reasons for non-use were lack of computer skills and preferring traditional means of consultation. ConclusionsOnly 27.2% (79/290) of frail older enrolled in the POHC intervention used the POHC frequently. For implementation of personal online health communities, older people with active health problems and a sizable number of health care providers should be targeted, and the informal caregiver, if present, should be involved in the implementation process. Trial RegistrationInternational Standard Randomized Controlled Trial Number (ISRCTN): 11165483; http://www.controlled-trials.com/isrctn/pf/11165483 (Archived by WebCite at http://www.webcitation.org/6U3fZovoU).

Published
2014
Full Text
View/download PDF

6. A study protocol of external validation of eight COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting

Author

Zahra, Anum, Luijken, Kim, Abbink, Evertine J., van den Berg, Jesse M., Blom, Marieke T., Elders, Petra, Festen, Jan, Gussekloo, Jacobijn, Joling, Karlijn J., Melis, René, Mooijaart, Simon, Peters, Jeannette B., Polinder-Bos, Harmke A., van Raaij, Bas F. M., Smorenberg, Annemieke, la Roi-Teeuw, Hannah M., Moons, Karel G. M., and van Smeden, Maarten

Published
2023
Full Text
View/download PDF

11. External validation of six COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting

Author

Zahra, Anum, van Smeden, Maarten, Abbink, Evertine J., van den Berg, Jesse M., Blom, Marieke T., van den Dries, Carline J., Gussekloo, Jacobijn, Wouters, Fenne, Joling, Karlijn J., Melis, René, Mooijaart, Simon P., Peters, Jeannette B., Polinder-Bos, Harmke A., van Raaij, Bas F.M., Appelman, Brent, la Roi-Teeuw, Hannah M., Moons, Karel G.M., and Luijken, Kim

Published
2024
Full Text
View/download PDF

20. The Association of Sedentary Behaviour and Cognitive Function in People Without Dementia: A Coordinated Analysis Across Five Cohort Studies from COSMIC

Author

Maasakkers, Carlijn M, Claassen, Jurgen AHR, Gardiner, Paul A, Olde Rikkert, Marcel GM, Lipnicki, Darren M, Scarmeas, Nikolaos, Dardiotis, Efthimios, Yannakoulia, Mary, Anstey, Kaarin J, Cherbuin, Nicolas, Haan, Mary N, Kumagai, Shuzo, Narazaki, Kenji, Chen, Tao, Ng, Tze Pin, Gao, Qi, Nyunt, Ma SZ, Crawford, John D, Kochan, Nicole A, Makkar, Steve R, Sachdev, Perminder S, Thijssen, Dick HJ, and Melis, René JF

Subjects
Alzheimer's Disease, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, Prevention, Neurosciences, Dementia, Aging, Acquired Cognitive Impairment, Neurological, Aged, Cognition, Cognitive Dysfunction, Cohort Studies, Female, Humans, Male, Sedentary Behavior, Surveys and Questionnaires, COSMIC Collaborators, Mechanical Engineering, Human Movement and Sports Sciences, Curriculum and Pedagogy, Sport Sciences
Abstract

BackgroundBesides physical activity as a target for dementia prevention, sedentary behaviour is hypothesized to be a potential target in its own right. The rising number of persons with dementia and lack of any effective treatment highlight the urgency to better understand these modifiable risk factors. Therefore, we aimed to investigate whether higher levels of sedentary behaviour are associated with reduced global cognitive functioning and slower cognitive decline in older persons without dementia.MethodsWe used five population cohorts from Greece, Australia, USA, Japan, and Singapore (HELIAD, PATH, SALSA, SGS, and SLAS2) from the Cohort Studies of Memory in an International Consortium. In a coordinated analysis, we assessed the relationship between sedentary behaviour and global cognitive function with the use of linear mixed growth model analysis (mean follow-up range of 2.0-8.1 years).ResultsBaseline datasets combined 10,450 older adults without dementia with a mean age range between cohorts of 66.7-75.1 years. After adjusting for multiple covariates, no cross-sectional association between sedentary behaviour and cognition was found in four studies. One association was detected where more sedentary behaviour was cross-sectionally linked to higher cognition levels (SLAS2, B = 0.118 (0.075; 0.160), P  0.05).ConclusionsOverall, these results do not suggest an association between total sedentary time and lower global cognition in older persons without dementia at baseline or over time. We hypothesize that specific types of sedentary behaviour may differentially influence cognition which should be investigated further. For now, it is, however, too early to establish undifferentiated sedentary time as a potential effective target for minimizing cognitive decline in older adults without dementia.

Published
2020

28. Quantitative Approaches to Examine Resilience and Aging

Author

Kok, Almar A. L., Huisman, Martijn, Cosco, Theodore D., Melis, René J. F., Linkov, Igor, Series Editor, Keisler, Jeffrey, Series Editor, Lambert, James H., Series Editor, Rui Figueira, Jose, Series Editor, Wister, Andrew V., editor, and Cosco, Theodore D., editor

Published
2020
Full Text
View/download PDF

32. Defeating Alzheimer's disease and other dementias: a priority for European science and society

Author

Winblad, Bengt, Amouyel, Philippe, Andrieu, Sandrine, Ballard, Clive, Brayne, Carol, Brodaty, Henry, Cedazo-Minguez, Angel, Dubois, Bruno, Edvardsson, David, Feldman, Howard, Fratiglioni, Laura, Frisoni, Giovanni B, Gauthier, Serge, Georges, Jean, Graff, Caroline, Iqbal, Khalid, Jessen, Frank, Johansson, Gunilla, Jönsson, Linus, Kivipelto, Miia, Knapp, Martin, Mangialasche, Francesca, Melis, René, Nordberg, Agneta, Rikkert, Marcel Olde, Qiu, Chengxuan, Sakmar, Thomas P, Scheltens, Philip, Schneider, Lon S, Sperling, Reisa, Tjernberg, Lars O, Waldemar, Gunhild, Wimo, Anders, and Zetterberg, Henrik

Subjects
Alzheimer Disease, Biomedical Research, Dementia, Europe, Humans, Clinical Sciences, Neurosciences, Neurology & Neurosurgery
Published
2016

34. Quantifying resilience of humans and other animals

Author

Scheffer, Marten, Bolhuis, J. Elizabeth, Borsboom, Denny, Buchman, Timothy G., Gijzel, Sanne M. W., Goulson, Dave, Kammenga, Jan E., Kemp, Bas, van de Leemput, Ingrid A., Levin, Simon, Martin, Carmel Mary, Melis, René J. F., van Nes, Egbert H., Romero, L. Michael, and Rikkert, Marcel G. M. Olde

Published
2018

40. DementiaNet facilitates a sustainable transition toward integrated primary dementia care: A long‐term evaluation.

Author

Oostra, Dorien L., Nieuwboer, Minke S., Melis, René J. F., Remers, Toine E. P., Olde Rikkert, Marcel G. M., and Perry, Marieke

Abstract

INTRODUCTION: Care integration is a promising strategy to achieve sustainable health‐care systems. With DementiaNet, a 2‐year program, we facilitated collaboration between primary health‐care professionals. We studied changes in primary dementia care integration during and after DementiaNet participation. METHODS: A longitudinal follow‐up study was performed. Networks started between 2015 and 2020; follow‐up ended in 2021. Quantitative and quantitative data were collected annually to assess quality of care, network collaboration, and number of crisis admissions. Growth modeling was used to identify changes over time. RESULTS: Thirty‐five primary care networks participated. Network collaboration and quality of care of newly formed networks increased significantly in the first 2 years (respectively, 0.35/year, P <.001; 0.29/year, P <.001) and thereafter stabilized. CONCLUSION: Primary care networks improved their collaboration and quality of care during DementiaNet participation, which persisted after the program ended. This indicates that DementiaNet facilitated a sustainable transition toward integrated primary dementia care. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

46. Physical Resilience in Daily Functioning Among Acutely Ill Hospitalized Older Adults: The Hospital-ADL Study

Author

Reichardt, Lucienne A., Aarden, Jesse, van Seben, Rosanne, van der Schaaf, Marike, van der Esch, Martin, Engelbert, Raoul H.H., Twisk, Jos W.R., Bosch, Jos A., Kuper, Ingeborg, de Jonghe, Annemarieke, Leguit-Elberse, Maike, Kamper, Ad, Posthuma, Nynke, Brendel, Nienke, Wold, Johan, Kolk, Daisy, Melis, René J.F., MacNeil-Vroomen, Janet L., and Buurman, Bianca M.

Published
2022
Full Text
View/download PDF

47. Unravelling complex primary-care programs to maintain independent living in older people: a systematic overview

Author

Smit, Linda C., Schuurmans, Marieke J., Blom, Jeanet W., Fabbricotti, Isabelle N., Jansen, Aaltje P.D., Kempen, Gertrudis I.J.M., Koopmans, Raymond, Looman, Willemijn M., Melis, Rene J.F., Metzelthin, Silke F., Moll van Charante, Eric P., Muntinga, Maaike E., Ruikes, Franca G.H., Spoorenberg, Sophie L.W., Suijker, Jacqueline J., Wynia, Klaske, Gussekloo, Jacobijn, De Wit, Niek J., and Bleijenberg, Nienke

Published
2018
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results