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Your search keyword '"Nuño,L"' showing total 194 results
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194 results on '"Nuño,L"'

1. Identification of human circulating factors following remote ischemic conditioning (RIC): Potential impact on stroke

Author

Mollet, Inês G., Viana-Soares, Ricardo, Cardoso-Pires, Catarina, Soares, Nuno L., Marto, João Pedro, Mendonça, Marcelo, Queiroga, Cláudia S.F., Carvalho, Ana S., Sequeira, Catarina O., Teixeira-Santos, Luísa, Fernandes, Tatiana P., Aloria, Kerman, Pereira, Sofia A., Matthiesen, Rune, Viana-Baptista, Miguel, and Vieira, Helena L.A.

Published
2024
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3. POS0478 SURVIVALTO b/tsDMARDs IN PATIENTS AFTER FULFILLING DIFFICULT-TO-TREAT RHEUMATOID ARTHRITIS CLASSIFICATION

Author

Novella-Navarro, M., primary, Ruiz, V., additional, López-Juanes, N., additional, Chacur, C. A., additional, Monjo-Henry, I., additional, Nuño, L., additional, Kafati Sarmiento, M. G., additional, Peiteado, D., additional, Villalba, A., additional, Fernández-Fernández, E., additional, Sanz-Jardón, M., additional, Sanmarti, R., additional, Plasencia-Rodríguez, C., additional, and Balsa, A., additional

Published
2024
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18. OP0204 CIRCULATING CD4+CXCR5+PD-1HI FOLLICULAR HELPER T CELLS ARE ELEVATED IN PATIENTS WITH RHEUMATOID ARTHRITIS AND PREDICT TREATMENT RESPONSE TO ABATACEPT OR TNF BLOCKERS

Author

Monjo, I., primary, Nieto-Carvalhal, B., additional, Uyaguari, M. D. C., additional, Villalba, A., additional, Nuño, L., additional, Peiteado, D., additional, Fernandez, E., additional, Garcia-Carazo, S., additional, Balsa, A., additional, and Miranda-Carus, M. E., additional

Published
2023
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21. Phase I/II Clinical Trials of Donor-Derived Purified Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft Versus Host Disease

Author

Soares, Maria VD, Escamilla Gomez, Virginia, Azevedo, Rita I, Pereira, Paulo N.G., Velázquez, Teresa Caballero, Garcia-Calderón, Clara B., Tharmaratnam, Kukatharmini, Cabral, Inês A, Ribeiro, Ana C, Mendes, Laura, Juncal, Clara, Roncon, Susana, Pais, Ana Teresa, Alho, Ana C, Rodriguez Gil, Alfonso, Espada, Eduardo L, Rodrigues, Anabela, Garção, Ana, Yaspo, Marie-Laure, Warnatz, Hans-Jörg, Lehrach, Hans, Barbosa-Morais, Nuno L., Quintas, Ana Miguel, Palmela, Paulo, Caldas, Cecilia, Ferreira, Rosa, Leite, Luis, Martins, Carlos, Lourenço, Fernanda, Moreno, Raúl, Raposo, João, Campilho, Fernando, Cheyne, Christopher Paul, Garcia-Fiñana, Marta, Campos, António, Baron, Frédéric, Arpinati, Mario, Edinger, Matthias, Ritz, Jerome, Vaz, Carlos Pinho, Perez-Simon, Jose A., and Lacerda, Joao F

Published
2022
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22. POS0907 ASSOCIATION BETWEEN DISEASE ACTIVITY AND DAMAGE IN IDIOPATHIC INFLAMMATORY MYOPATHIES. DIFFERENCES BETWEEN INCIDENT AND PREVALENT CASES

Author

Cobo-Ibáñez, T., primary, Seoane-Mato, D., additional, Carrión Barberà, I., additional, Castellví, I., additional, Nuño, L., additional, Martínez-Barrio, J., additional, Jovani, V., additional, Romero Bueno, F., additional, Ruiz Lucea, E., additional, Tomero Muriel, E., additional, Trallero-Araguás, E., additional, Narváez, J., additional, Camins Fabregas, J., additional, Ruiz Román, A., additional, Loarce-Martos, J., additional, Holgado, S., additional, Esmeralda, D. F., additional, Sivera, F., additional, Merino Argumánez, C., additional, Mas, A. J., additional, Tandaipan, J. L., additional, Plasencia, C., additional, Gomez-Gomez, A., additional, Sanchez Pernaute, O., additional, Pego-Reigosa, J. M., additional, Joven-Ibáñez, B., additional, Belzunegui, J., additional, Carrasco-Cubero, C., additional, Freire González, M., additional, Naveda, E., additional, Lozano Rivas, N., additional, Suarez Cuba, J. D., additional, Martínez González, O., additional, Ortega Castro, R., additional, and Alcocer-Amores, P., additional

Published
2022
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23. AB0376 DIFFERENCES IN IMMUNOGLOBULIN LEVELS IN PATIENTS WITH ANCA-ASSOCIATED VASCULITIS AND RHEUMATOID ARTHRITIS TREATED WITH RITUXIMAB

Author

Sanz, M., primary, Oñoro López, C. M., additional, Bonilla, G., additional, Peiteado, D., additional, Noblejas Mozo, A., additional, Robles Marhuenda, Á., additional, Rios, J. J., additional, Benavent, D., additional, Plasencia, C., additional, Nuño, L., additional, Monjo, I., additional, Villalba, A., additional, and Balsa, A., additional

Published
2022
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25. Early monitoring of infliximab serum trough levels predicts long-term therapy failure in patients with axial spondyloarthritis

Author

Martínez-Feito, A, primary, Navarro-Compán, V, additional, Hernández-Breijo, B, additional, Olariaga-Mérida, E, additional, Peiteado, D, additional, Villalba, A, additional, Nuño, L, additional, Monjo, I, additional, Diego, C, additional, Pascual-Salcedo, D, additional, Nozal, P, additional, Balsa, A, additional, and Plasencia-Rodríguez, C, additional

Published
2021
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28. POS0617 ANTI INFLIXIMAB ANTIBODIES DETECTED BY A DRUG TOLERANT ASSAY ARE FREQUENT BUT, IN MANY CASES, WITHOUT RELEVANT CLINICAL SIGNIFICANCE

Author

Martínez-Feito, A., primary, Hernández-Breijo, B., additional, Novella-Navarro, M., additional, Navarro-Compán, V., additional, Diego, C., additional, Monjo, I., additional, Nuño, L., additional, Villalva, A., additional, Peiteado, D., additional, Pascual-Salcedo, D., additional, Nozal, P., additional, Balsa, A., additional, and Plasencia, C., additional

Published
2021
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29. POS1260 FACTORS ASSOCIATED WITH SEVERE SARS-COV-2 INFECTION IN PATIENTS WITH INFLAMMATORY RHEUMATIC DISEASES IN MADRID: RESULTS FROM REUMA-COVID SORCOM REGISTRY

Author

Boteanu, A., primary, García Fernández, A., additional, De la Torre, N., additional, Pavia Pascual, M., additional, Sanchez Pernaute, O., additional, Recuero Diaz, S., additional, Perez Esteban, S., additional, Bonilla, G., additional, Nuño, L., additional, Sanmartin Martinez, J. J., additional, Bonilla Gonzalez-Leganá, C., additional, Clemente Garulo, D., additional, Lojo Oliveira, L., additional, Rodríguez Herredia, J. M., additional, and Bachiller-Corral, J., additional

Published
2021
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30. Early monitoring of infliximab serum trough levels predicts long-term therapy failure in patients with axial spondyloarthritis.

Author

Martínez-Feito, A, Navarro-Compán, V, Hernández-Breijo, B, Olariaga-Mérida, E, Peiteado, D, Villalba, A, Nuño, L, Monjo, I, Diego, C, Pascual-Salcedo, D, Nozal, P, Balsa, A, and Plasencia-Rodríguez, C

Subjects
SPONDYLOARTHROPATHIES, INFLIXIMAB, RECEIVER operating characteristic curves, TERMINATION of treatment, ANKYLOSING spondylitis
Abstract

To evaluate whether serum infliximab trough levels (ITL) during the early stages of treatment are predictive of long-term clinical failure in patients with axial spondyloarthritis (axSpA). Longitudinal observational study involving 81 patients with axSpA monitored during infliximab therapy. Serum ITL were measured before starting infliximab treatment and at weeks 2 (W2), W6 and W12 of treatment. Disease activity was assessed by Ankylosing Spondylitis Disease Activity Score (ASDAS) at baseline, W24 and W52, and every 6 months thereafter until treatment discontinuation, regardless of the reason. Non-clinically important improvement was defined by ΔASDAS<1.1. The association between serum levels during the early stages and clinical outcomes (non-clinically important improvement at W52, drug survival and drop-out due to secondary inefficacy) was investigated through logistic regression models and Kaplan Meier curves. Receiver operating characteristic (ROC) curves were employed to determine the best cut-off for serum ITL. Out of the 81 patients, 45 (56%) did not achieve clinical improvement at W52. These patients had lower serum ITL at W12 compared to those who improved: ITL [median (IQR)]: 4.1(0.9-8.3) µg/mL vs 7.1 (4.3–11.3) µg/mL, respectively;p = 0.007). ITL<6.7 µg/mL at W12 was significantly associated with: i) not achieving clinical improvement at W52 (OR: 2.3; 95%CI: 1.3–3.9); ii) shorter drug survival (5.0 years (95% CI 3.8–6.2) vs 7.0 years (95% CI 4.8–6.9; p = 0.04), and iii) higher drop-out rates due to secondary inefficacy (OR: 3.5; 95% CI: 1.2–10.2). Low serum ITL at W12 were associated with long-term clinical failure in patients with axSpA, due to secondary inefficacy. [ABSTRACT FROM AUTHOR]

Published
2022
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35. AB0646 IS IT FEASIBLE TO ACHIEVE RECOMMENDED THERAPEUTICAL TARGET IN PATIENTS WITH AXIAL SPONDYLARTHRITIS IN CLINICAL PRACTICE? DATA FROM THE SpA-Paz COHORT

Author

Franco Gomez, K. N., primary, Plasencia, C., additional, Novella-Navarro, M., additional, Benavent, D., additional, Bogas, P., additional, Nieto, R., additional, Monjo, I., additional, Nuño, L., additional, Villalva, A., additional, Peiteado, D., additional, Balsa, A., additional, and Navarro-Compán, V., additional

Published
2020
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37. AB0030 INCREASED CIRCULATING CD19+CD24HICD38HI REGULATORY B CELLS ARE BIOMARKERS OF RESPONSE TO METHOTREXATE IN EARLY RHEUMATOID ARTHRITIS

Author

Fortea-Gordo, P., primary, Villalba, A., additional, Nuño, L., additional, Santos-Bornez, M. J., additional, Peiteado, D., additional, Monjo, I., additional, Puig-Kröger, A., additional, Sanchez-Mateos, P., additional, Martín-Mola, E., additional, Balsa, A., additional, and Miranda-Carus, M. E., additional

Published
2020
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41. Procedure to obtain activated carbons from Pecán nutshell

Author

Uribe, K., Cortés, A. L., Contreras, J. L., Nuño, L., Quintana, Berenice, López M., Ricardo, Vázquez R., Tamara, Uribe, K., Cortés, A. L., Contreras, J. L., Nuño, L., Quintana, Berenice, López M., Ricardo, and Vázquez R., Tamara

Abstract

In the present study, activated carbons were obtained from vegetable Pecán nutshell by physical activation with water vapor, for which an electric furnace and a steam generator were adapted to a tubular rotary pyrolysis reactor where the carbonization of the particles was carried out to proceed immediately to activation. The activation temperature was from 600 to 800 °C and the activation time was from 0.5 to 2.0 h. The activated carbons obtained were characterized by: specific surface area, pore size distribution, pH and moisture content. The obtained N2 isotherms were adjusted to the Langmuir equation. The minimum specific surface area reached was 246 m2/g and the maximum value was 542 m2/g. The BJH model was used to analyze the results of pore distribution, observing a bimodal behavior where mesoporosity prevails and microporosity remains in second place. The pH varied from 6 to 13 and the moisture content was determined from 1.01 to 6.45%. The temperature and activation time for the largest specific area of 542 m2 / g were 800 ° C and 2 h, with a pH of 13, En el presente trabajo se obtuvieron carbones activados a partir de desechos vegetales mediante activación física con vapor de agua, para lo cual fueron adaptados un horno eléctrico y un generador de vapor a un reactor tubular rotatorio de pirolisis donde se llevó a cabo la carbonización de las muestras para en seguida proceder a la activación. El desecho vegetal utilizado fue cáscara de nuez de Pecán de México. La temperatura de activación fue de 600 a 800 °C y el tiempo de activación fue de 0.5 a 2.0 horas. Se caracterizaron los carbones activados obtenidos mediante pruebas de: área específica, distribución de tamaño de poros, pH y contenido de humedad. Las isotermas obtenidas se ajustaron a la ecuación de Langmuir. El área específica mínima alcanzada fue de 246 m2/g y el valor máximo fue de 542 m2/g. Se empleó el modelo BJH para el análisis de los resultados de distribución de poros observando un comportamiento bimodal donde prevalece la mesoporosidad y quedando en segundo término la microporosidad. El pH varió de 6 a 13 y el contenido de humedad se determinó desde 1.01 a 6.45 %. La temperatura y tiempo de activación para la mayor área específica de 542 m2/g fueron 800°C y 2 h y con un pH de 13

Published
2019

42. Introducing the construct of risky cannabis use: designing and piloting a co-created educational intervention on cannabis health literacy among adolescents and young adults. The CAHLY (CAnabis Health LiteracY) study.

Author

Caballeria, E., Oliveras, C., Guzmán, P., Ballbé, M., Fleur, B., Pol, B., Ilzarbe, D., López-Pelayo, H., Matrai, S., Artigas, M., Pons-Cabrera, M. T., Folch, D., Nuño, L., and Balcells-Oliveró, M.

Subjects
YOUNG adults, HEALTH literacy, PARTICIPATORY design, MEDICAL personnel, COLLEGE students
Abstract

Introduction: Cannabis use poses a significant risk to the psychological wellbeing of youth, affecting academic performance and potentially triggering the onset of mental health issues. Providing young people with comprehensive information about patterns of cannabis use and specific factors that increase an individual's health risks is crucial. The ability to critically assimilate this information is known as health literacy (HL). Objectives: To design a psychoeducational intervention to increase HL on risky cannabis use among students aged 16-25, and to assess its usability and feasibility. Methods: We designed a psychoeducational intervention based on the outcomes of a 3-hour co-creation session involving healthcare professionals and students. 29 university students and 25 high-school students completed this intervention and assessed its usability and feasibility with the SUS (System Usability Scale), PSSUQ (Post-Study System Usability Questionnaire) and additional open questions regarding the most and less-liked aspects of the intervention. Results: The design phase resulted in an informative website (http://www.cahlyclinic.cat/) and a 1-hour structured onsite educator-facilitated session, comprising 3 group activities (completed on paper or online) addressing three dimensions of cannabis HL: searching for, interpreting and applying reliable information. Usability of the intervention was rated as excellent (SUS mean score>80). PSSUQ results indicate that students were satisfied with the intervention; found the HL information clear, relevant, and adequate for their needs; found the interface of the digital version pleasant and usable without support; and would recommend it to other students. Conclusions: We propose an innovative structured and usable intervention, designed using a participatory approach, which aims to disseminate information on risky cannabis use to a key target population, namely young people. Disclosure of Interest: None Declared [ABSTRACT FROM AUTHOR]

Published
2024
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