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Objective: to find an association between the serum CA-125 level and the histopathological type of ovarian tumor. Study Design: Cross-sectional study. Place and Duration of Study: Medical Oncology, Jinnah postgraduate Medical Center, Karachi Pakistan from Jan 2018 to Dec 2019. Methodology: This study included 107 patients presenting with epithelial ovarian cancer. In each case, histological type, pathological stage, degree of differentiation and serum CA-125 was evaluated. The association between preoperative CA-125 and histopathological type of tumor were evaluated. Result: About 107 ovarian cancer patients were included. The mean age in our study was 50.80±10.16 years. Raised CA-125 level was found in most of the patients with serous histology 46(56.1%). Conclusion: Serum level CA-125 elevated in most patients with serous histology. A statistically non-significant association was found between raise CA-125 levels and histological types of ovarian cancer. [ABSTRACT FROM AUTHOR]

Introduction- One of the most significant therapeutic herbs in the Symplocaceae family is Lodhra (Symplocos racemosa roxb). It possesses several anti-inflammatory, anti-acne, anti-ulcer, antioxidant, and anti-diabetic qualities. It is widely used to treat a wide range of illnesses, including Alzheimer's, PCOS, leprosy, and many more. Objective- The purpose of this study was to develop nutraceutical products incorporating dehydrated Lodhra bark powder, such as Lodhra Powder Chyawanprash and Lodhra Orange Squash, and then assess their sensory and nutritional properties. Method- Along with control (T0), three variations (treatments) of the lodhra powder Chyawanprash T1, T2, and T3, were prepared, which contain 1g, 3 g, and 5g of lodhra powder, respectively. Along with control (T0), five variations (treatments) of the lodhra orange squash (T1, T2, T3 T4 and T5) were prepared, which contain 1g, 2g, 3g, 4 g, and 5g of lodhra powder respectively. The sensory attributes of products were analysed organoleptically by the panel of judges using a 9-point hedonic scale score card. The nutritional composition of value-added products was calculated using AOAC 2020 standard procedure.Result- The lodhra powder product was more nutritious as the addition of lodhra powder increased the fiber content of the product. It can be concluded that the addition of lodhra powder adds a fragrance and taste, and it also enhances the quality of lodhra powder chyawanprash and lodhra orange squash. Conclusion- It was concluded that the addition of lodhra powder added therapeutic value for reducing leucorrhea and improving reproductive health in the female population. It also enhanced the quality of the prepared nutraceuticals. [ABSTRACT FROM AUTHOR]