Semmler, Georg, Traugott, Marianna Theresia, Graninger, Marianne, Hoepler, Wolfgang, Seitz, Tamara, Kelani, Hasan, Karolyi, Mario, Pawelka, Erich, Aragón de La Cruz, Sara, Puchhammer-Sto¨ckl, Elisabeth, Aberle, Stephan Walter, Stiasny, Karin, Zoufaly, Alexander, Aberle, Judith Helene, and Weseslindtner, Lukas
In this study, we comprehensively analyzed multispecific antibody kinetics of different immunoglobulins in hospitalized patients with acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Three hundred fifty-four blood samples longitudinally obtained from 81 IgG-seroconverting progressed coronavirus disease 2019 (CoVID-19) patients were quantified for spike 1 (S1), S2, and nucleocapsid protein (NCP)-specific IgM, IgA, IgG, and total Ig antibodies using a microarray, 11 different enzyme-linked immunosorbent assays (ELISAs)/chemiluminescence immunoassays (CLIAs), and 1 rapid test by seven manufacturers.