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Your search keyword '"REZNIK, Vitaly"' showing total 18 results
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18 results on '"REZNIK, Vitaly"'

2. New coronavirus infection in a child at the age of 2 years 4 months with acute lymphoblastic leukemia (fatal case)

Author

Ivanov, Dmitry O., primary, Petrenko, Yury V., additional, Reznik, Vitaly A., additional, Nasyrov, Ruslan A., additional, Timchenko, Vladimir N., additional, Pavlova, Elena B., additional, Pavlova, Natalia V., additional, Bannova, Svetlana L., additional, Krasnogorskaya, Olga L., additional, Kondratyev, Gleb V., additional, Chernova, Tatyana M., additional, Shakmaeva, Maria A., additional, Chepelev, Alexander S., additional, and Galichina, Veronika A., additional

Published
2022
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13. RELATION BETWEEN THE SEVERITY OF THE COURSE OF THE DISEASE AND DOSES AND RADIATION RISK OF THE CHEST X-RAY AND CT EXAMINATION OF CHILDREN WITH COVID-19.

Author

SHATSKIY, Ilia, IVANOV, Dmitry, REZNIK, Vitaly, POZDNYAKOV, Aleksandr, PUZYREV, Viktor, KAPYRINA, Yuliya, NABIEVA, Anna, PANUNTSEVA, Karine, BANNOVA, Svetlana, and PETRENKO, Yury

Subjects
DISABILITIES, RADIATION doses, RISK perception, RADIATION protection, COVID-19
Abstract

The effective doses and radiation risks of X-ray and CT examinations for children during the diagnosis and treatment of COVID-19 were assessed and the dependence of the number of examinations and the total radiation risk for one patient on the severity of the disease was analyzed. Sufficient grounds to assert if the severity of the course of the disease is associated with radiation risks from the performed CT examinations have not been received. [ABSTRACT FROM AUTHOR]

Published
2021

16. Antibody against Na/K-ATPase Inhibitor Lowers Blood Pressure and Increases Vascular Fli1 in Experimental Preeclampsia.

Author

Agalakova, Natalia I, Reznik, Vitaly A, Nadei, Olga V, Ershov, Ivan A, Rassokha, Olga S, Vasyutina, Marina L, Ivanov, Dmitry O, Adair, C David, Galagudza, Michael M, and Bagrov, Alexei Y

Subjects
BLOOD pressure, CARDIAC glycosides, PREECLAMPSIA, UMBILICAL arteries, HYPOTENSION
Abstract

BACKGROUND Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). We demonstrated that MBG induces fibrosis via mechanism involving inhibition of Fli1, a nuclear transcription factor and a negative regulator of collagen-1 synthesis. We hypothesized that PE blockade of increased MBG with antibody would lessen the fibrosis of umbilical arteries and lower the blood pressure in rats with PE. METHODS We tested 36 pregnant Sprague-Dawley rats in which 12 were made hypertensive by 1.8% Na supplementation (days 6–19 of gestation), 12 pregnant rats served controls. At day 19, PE rats received one intraperitoneal injection of polyclonal anti-MBG-4 antibody (0.5 ug/ml) for 4 hours. RESULTS PE was associated with higher blood pressure (117 ± 2 vs. 107 ± 2 mm Hg; P < 0.01), plasma MBG levels (1.54 ± 0.34 vs. 0.49 ± 0.11 nmol/L; P < 0.01), protein excretion (26 vs. 12 mg/24 hours), sFlt-1 (3-fold), decrease in Fli1 (7-fold) and increase in collagen-1 in aorta (4-fold) vs. control rats (all P < 0.01). In 12 rats treated with polyclonal anti-MBG-4 antibody blood pressure dropped (93 ± 3 mm Hg) and Fli1 was decreased much less (2-fold; P < 0.01 vs. nontreated rats). CONCLUSIONS These results demonstrate that in experimental PE elevated MBG level is implicated in umbilical fibrosis via suppression of Fli1. [ABSTRACT FROM AUTHOR]

Published
2020
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17. Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia

Author

Fedorova, Olga, primary, Ishkaraeva, Valentina, additional, Grigorova, Yulia, additional, Reznik, Vitaly, additional, Kolodkin, Nikolai, additional, Zazerskaya, Irina, additional, Zernetkina, Valentina, additional, Agalakova, Natalia, additional, Tapilskaya, Natalia, additional, Adair, C., additional, Lakatta, Edward, additional, and Bagrov, Alexei, additional

Published
2018
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