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Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose: To investigate whether MMP-13 g.-77 A > G (rs2252070) gene polymorphism is associated with early implant loss. Materials and Methods: Two hundred nonsmoking volunteers in good oral health, > 18 years of age, and found to be periodontally healthy by clinical examination were matched by age, sex, and implant position and separated into two groups: control group (100 patients with one or more healthy implants for a minimum of 1 year) and test group (100 patients who had suffered early implant loss, considered when implants presented mobility and/or pain before or during abutment connection, requiring their removal). Genomic DNA from saliva was genotyped by PCR-RFLP. Statistical analysis of the results was done using Mann-Whitney U and chi-square tests, with a significance level of 5%. Results: A significant difference in the presence of the different alleles and genotype was found between groups for the MMP-13 g.-77 A > G (rs2252070) gene polymorphism (P = .0161, OR 95% = 0.57 [0.37 to 0.89]; P = .007, OR 95% = 0.44 [0.25 to 0.78]). The A allele increased susceptibility to early implant loss and appeared to be a genetic risk factor. Conclusion: The findings suggest that MMP-13 g.-77 A > G (rs2252070) polymorphism may contribute to early implant loss. [ABSTRACT FROM AUTHOR]

The purpose of this study was to evaluate the effect of 12 wks of high-intensity interval training (HIIT) on butyrylcholinesterase (BChE) and cardiovascular risk factors in obese adolescents. The subjects were 54 obese adolescents, divided into two groups: the high-intensity interval training group (HIITG, n = 20) and the control group (CG, n = 34). The HIIT resulted in a significant decrease in BMI z-score, WC, TC, LDL-C and BChE activity (P<0.05). The CG showed a significant increase in BChE (P = 0.05) with no change in BMI, BMI z-score, CC, TC, LDL-C, HDL-C and TG. The decrease in BChE activity with HIIT training was accompanied by the decrease in biochemical markers, thus indicating that the BChE activity can be used as a secondary marker for cardiovascular risk factors that are associated with child and adolescent obesity. [ABSTRACT FROM AUTHOR]