406 results on '"Sesaki, Hiromi"'
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2. Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard
3. mCAUSE: Prioritizing mitochondrial targets that alleviate pancreatic cancer cell phenotypes
4. Mechanistic insights into metabolic function of dynamin-related protein 1
5. Systemic phospho-defective and phospho-mimetic Drp1 mice exhibit normal growth and development with altered anxiety-like behavior
6. The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury
7. Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation
8. Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
9. Partial skeletal muscle-specific Drp1 knockout enhances insulin sensitivity in diet-induced obese mice, but not in lean mice
10. Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation
11. Novel role of dynamin‐related‐protein 1 in dynamics of ER‐lipid droplets in adipose tissue
12. Endoplasmic reticulum–associated degradation regulates mitochondrial dynamics in brown adipocytes
13. An LKB1–mitochondria axis controls TH17 effector function
14. Role of human HSPE1 for OPA1 processing independent of HSPD1
15. Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis
16. Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
17. C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly
18. The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma
19. Loss of dynamin-related protein 1 (Drp1) does not affect epidermal development or UVB-induced apoptosis but does accelerate UVB-induced carcinogenesis
20. Protocol for measuring mitochondrial size in mouse and human liver tissues
21. The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged mice
22. OPA1 protects intervertebral disc and knee joint health in aged mice by maintaining the structure and metabolic functions of mitochondria
23. Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease.
24. Dynamin-1–Like Protein Inhibition Drives Megamitochondria Formation as an Adaptive Response in Alcohol-Induced Hepatotoxicity
25. Inhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer
26. Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
27. Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation
28. Mitochondrial Fission Mediates Endothelial Inflammation
29. Phosphorylated Rho–GDP directly activates mTORC2 kinase towards AKT through dimerization with Ras–GTP to regulate cell migration
30. A nucleotide diphosphate kinase mediates tethering between mitochondria prior to fusion
31. DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons
32. Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation
33. Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation
34. Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method
35. A Heterozygous Mutation in MFF Associated with a Mild Mitochondrial Phenotype
36. Abstract 1888: The protein optic atrophy 1 (OPA1) functions as a novel assembly factor for the respiratory complex V, and its deletion is tolerated in the liver
37. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance
38. An AAA-ATPase links mitochondrial division with DNA nucleoids
39. Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis
40. DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders
41. CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis
42. Role of human HSPE1 for OPA1 processing independent of HSPD1
43. Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effectson mitochondrial fusion and fission
44. Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development
45. Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
46. 148-OR: Partial Knockout of Skeletal Muscle Dynamin-Related Protein 1 Improves Insulin Sensitivity in Diet-Induced Insulin Resistant Mice, but Not in Normal Control Mice
47. DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
48. The Role of the Optic Atrophy 1 (OPA1) Protein in Drug‐Induced Liver Injury
49. Loss of hepatic Drp1 contributes to alcohol‐induced megamitochondria and exacerbates alcoholic hepatitis via impaired mitophagy and mitochondrial lipid oxidation
50. Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver
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