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Traditional embroidery is an important handicraft in China, which has a cultural background of thousands of years and is also one of the important components of Chinese folk art. Combining traditional embroidery art with modern fashion design can form modern fashion design and provide good materials for the long-term development of fashion design in China. Combining embroidery technology with modern fashion design can strengthen the level of modern fashion design in China and make the development of fashion design in China more national characteristics.

PDT-SPACE is an open-source software tool that automates interstitial photodynamic therapy treatment planning by providing patient-specific placement of light sources to destroy a tumor while minimizing healthy tissue damage. This work extends PDT-SPACE in two ways. The first enhancement allows specification of clinical access constraints on light source insertion to avoid penetrating critical structures and to minimize surgical complexity. Constraining fiber access to a single burr hole of adequate size increases healthy tissue damage by 10%. The second enhancement generates an initial placement of light sources as a starting point for refinement, rather than requiring entry of a starting solution by the clinician. This feature improves productivity and also leads to solutions with 4.5% less healthy tissue damage. The two features are used in concert to perform simulations of various surgery options of virtual glioblastoma multiforme brain tumors.

Objective An epidemic of obesity is prevalent in the world. Recent evidences have linked obesity to male infertility , but the underlying mechanisms remain to be elucidated. Although spermatozoa dysfunction is the most cause of infertility and defective mitochondrial function plays a key role in impairing the sperm quality , there was little study on the role of mitochondria within spermatozoa in obese male infertility. Methods In this study, the semen parameters in Chinese obesity (BMI ≥ 28 kg/m2, n = 51) and normal (BMI of 18.5 to 23.9 kg/m2, n = 42) volunteers were investigated. Moreover, the oxidative stress injury was explored in human spermatozoa by examining the activity of intracellular SOD and MDA in sperm and LDH release from sperm. The activity test of mitochondrial respiratory chain complexes and the mitochondrial membrane potential were also performed. Results We found that obesity had a negative influence on the quality of semen. Furthermore, oxidative stress was detected in sperm from obese males. Oxidative stress-related mitochondrial dysfunction was also observed in the spermatozoa of obese males. Conclusions In total, these results indicated that oxidative stress-related mitochondrial dysfunction might be a reason for obesity-induced infertility, which provided the insights into the pathophysiological mechanism behind obesity-induced infertility in obese human males.

This study aimed to identify predictors of rapid improvement of papilledema after stenting and develop a simple preintervention scale.A prospective cohort of idiopathic intracranial hypertension (IIH) with venous sinus stenosis (VSS) treated with stenting in a tertiary hospital from January 2014 to December 2019 was reviewed. We categorized papilledema improvement into favorable (grades 0-1) and unfavorable (grades 2-5). We employed logistic regression analysis to find the predictive factors and develop the predictive scale. We then estimated the performance of the scale using the ROC curve and Hosmer-Lemeshow test.There were 110 patients who underwent venous sinus stenting, with a mean age of 37.1 years and a predominance of females (77.3%). A total of 85 patients had a favorable outcome following stenting, while 25 patients had an unfavorable outcome. The results of the multivariate analysis indicate that lower preoperative pressure gradients (odds ratio, OR: 4.01; 95% confidence interval, CI: 1.27-12.68), stenosis rates (OR: 4.16; 95% CI: 1.11-15.56), and preoperative papilledema grades (OR: 2.92; 95% CI: 1.44-5.91) were independently associated with rapid improvement of papilledema following stenting treatment. The 3‑item scale exhibited good discrimination with an area under the curve (AOC) of 0.81 (95% CI 0.72-0.89, p 0.001), as well as acceptable calibration determined by the Hosmer-Lemeshow test (P = 0.42). The optimal cut-off value of the scale (range 0-6 points) was ≥ 4 points, with a sensitivity of 72%, specificity of 73%, and accuracy of 78%.The presence of lower preoperative pressure gradients, stenosis severity, and preoperative status of papilledema were identified as positive predictors of rapid improvement of the papilledema following stenting in IIH patients. The 3‑item scale provides a promising preintervention predictive model for predicting rapid response following stenting treatment in IIH patients with VSS.

BackgroundThis prospective cohort study compared the outcomes of stenting and medical treatment for patients with idiopathic intracranial hypertension (IIH) and venous sinus stenosis (VSS).MethodsIn this single-center cohort study, patients with IIH and VSS were evaluated between January 2014 and December 2019 with follow-up periods of 1, 3, and 6 months. The patients received either stenting or medical treatment. The two groups underwent 1:1 matching using propensity score analysis, and the clinical outcomes were compared.ResultsFollowing 1:1 matching, 36 patients who underwent stenting and 36 who underwent medical treatment were matched. The median improvements in the papilledema Frisén grade were greater in the stenting group at 1 month (−2 vs 0), 3 months (−3 vs −1), and 6 months (−3 vs −1) than in the medical treatment group. Patients who received stenting treatment had a significantly higher prevalence of complete resolution of their respective symptoms (headache, tinnitus, or visual disturbances) at 3 months (58.3% vs 13.9%, OR 8.68, 95% CI 2.74 to 27.52) and 6 months (80.6% vs 22.2%, OR 14.50, 95% CI 4.64 to 45.32) than those receiving medical treatment.ConclusionsThis matched-control study shows that stenting has a greater efficacy rate and rapid resolution of papilledema and its respective symptoms compared with medical treatment.

BACKGROUND College students are at-risk populations of the human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) and risky sexual behaviors (RSBs). However, little literature focuses on the comprehensive influence factors of RSB in China. OBJECTIVE This study aims to describe the RSB among college students in Wenzhou and explore potential influencing factors of RSB to provide references for HIV prevention and control. METHODS A cross-sectional survey was conducted from November to December 2020 in Wenzhou university city. Self-administered questionnaires were used to collect data anonymously. Some demographic questions, AIDS-related health education, sexual attitudes, condom use effectiveness, HIV awareness, HIV testing awareness and behavior, HIV self-perceived risk, and sexual behavior were investigated and analyzed. Chi-square test and logistic regression were used to analyze the factors associated with RSB. We also performed some sensitivity analyses, such as subgroup analyses according to gender. P-values RESULTS A total of 5627 college students were included in this survey. Of all participants, 353 (6.3%) had sexual behaviors, of which 79 (22.4%) students were engaged in RSB mainly including same-sex sex, casual sex, and unprotected sex. In the multivariable logistic regression analysis, higher-risk sexual attitudes (P CONCLUSIONS Prevalence of RSB among college students is on the rise. The prevalence of AIDS will increase dramatically if these RSBs persist. More comprehensive and specific education on HIV knowledge and RSB-related knowledge should be designed and offered to college students on campus.

Open-source software packages have been extensively used in the past three decades in medical imaging and diagnostics, aiming to study the feasibility of the application ex vivo. Unfortunately, most of the existing open-source tools require some software engineering background to install the prerequisite libraries, choose a suitable computational platform, and combine several software tools to address different applications.To facilitate the use of open-source software in medical applications, enabling computational studies of treatment outcomes prior to the complex in-vivo setting.FullMonteWeb, an open-source, user-friendly web-based software with a graphical user interface for interstitial photodynamic therapy (iPDT) modeling, visualization, and optimization, is introduced. The software can perform Monte Carlo simulations of light propagation in biological tissues, along with iPDT plan optimization. FullMonteWeb installs and runs the required software and libraries on Amazon Web Services (AWS), allowing scalable computing without complex set up.FullMonteWeb allows simulation of large and small problems on the most appropriate compute hardware, enabling cost improvements of 10 × versus always running on a single platform. Case studies in optical property estimation and diffuser placement optimization highlight FullMonteWeb's versatility.The FullMonte open source suite enables easier and more cost-effective in-silico studies for iPDT.

The effect of calcium supplementation on bone mineral accretion in people under 35 years old is inconclusive. To comprehensively summarize the evidence for the effect of calcium supplementation on bone mineral accretion in young populations (≤35 years).This is a systematic review and meta-analysis. The Pubmed, Embase, ProQuest, CENTRAL, WHO Global Index Medicus, Clinical Trials.gov, WHO ICTRP, China National Knowledge Infrastructure (CNKI), and Wanfang Data databases were systematically searched from database inception to April 25, 2021. Randomized clinical trials assessing the effects of calcium supplementation on bone mineral density (BMD) or bone mineral content (BMC) in people under 35 years old.This systematic review and meta-analysis identified 43 studies involving 7,382 subjects. Moderate certainty of evidence showed that calcium supplementation was associated with the accretion of BMD and BMC, especially on femoral neck (standardized mean difference [SMD] 0.627, 95% confidence interval [CI] 0.338-0.915; SMD 0.364, 95% CI 0.134-0.595; respectively) and total body (SMD 0.330, 95% CI 0.163-0.496; SMD 0.149, 95% CI 0.006-0.291), also with a slight improvement effect on lumbar spine BMC (SMD 0.163, 95% CI 0.008-0.317), no effects on total hip BMD and BMC and lumbar spine BMD were observed. Very interestingly, subgroup analyses suggested that the improvement of bone at femoral neck was more pronounced in the peripeak bone mass (PBM) population (20-35 years) than the pre-PBM population (20 years).Our findings provided novel insights and evidence in calcium supplementation, which showed that calcium supplementation significantly improves bone mass, implying that preventive calcium supplementation before or around achieving PBM may be a shift in the window of intervention for osteoporosis.This work was supported by Wenzhou Medical University grant [89219029].Osteoporosis and bone fractures are common problems among older people, particularly older women. These conditions cause disability and reduce quality of life. Progressive loss of bone mineral density is usually the culprit. So far, strategies to prevent bone weakening with age have produced disappointing results. For example, taking calcium supplements in later life only slightly reduces the risk of osteoporosis or fracture. New approaches are needed. Bone mass increases gradually early in life and peaks and plateaus around 20-35 years of age. After that period, bone mass slowly declines. Some scientists suspect that increasing calcium intake during this period of peak bone mass may reduce osteoporosis or fracture risk later in life. A meta-analysis by Liu, Le et al. shows that boosting calcium intake in young adulthood strengthens bones. The researchers analyzed data from 43 randomized controlled trials that enrolled 7,382 participants. About half the studies looked at the effects of taking calcium supplements and the other half analyzed the effects of a high calcium diet. Boosting calcium intake in people younger than age 35 improved bone mineral density throughout the body. It also increased bone mineral density at the femoral neck, where most hip fractures occur. Calcium supplementation produced larger effects in individuals between the ages of 20 and 35 than in people younger than 20. Both high calcium diets and calcium supplements with doses less than 1000 mg/d boosted bone strength. Higher dose calcium supplements did not provide any extra benefits. The analysis suggests people should pay more attention to bone health during early adulthood. Large randomized clinical trials are needed to confirm the long-term benefits of boosting calcium intake during early adulthood. But if the results are validated, taking calcium supplements, or eating more calcium-rich foods between the ages of 20 and 35 may help individuals build healthier bones and prevent fractures and osteoporosis later in life.

Salsola ferganica is a natural desert herbaceous plant in the arid area of western and northwestern China. Because of its salt tolerance and drought resistance, it is of great significance in desert afforestation and sand-fixing capacity. There has been much research on the genes involved in plants under desert stresses in recent years. The application of the best internal reference genes for standardization was a critical procedure in analyzing the gene expression under different types. Even so, the reference gene has not been reported in the application of gene expression normalization of S. ferganica. In this study, nine reference genes (TUA-1726, TUA-1760, TUB, GAPDH, ACT, 50S, HSC70, APT, and U-box) in S. ferganica were adopted and analyzed under six different treatments (ABA, heat, cold, NaCl, methyl viologen (MV), and PEG). The applicability of candidate genes was evaluated by statistical software, including geNorm, NormFinder, BestKeeper, and RefFinder, based on their stability values in all the treatments. These results indicated that the simultaneous selection of two stable reference genes would fully standardize the optimization of the normalization research. To verify the feasibility of the above internal reference genes, the CT values of AP2/ERF transcription factor family genes were standardized using the most (ACT) and least (GAPDH) stable reference genes in S. ferganica seedlings under six abiotic stresses. The research showed that HSC70 and U-box were the most appropriate reference genes in ABA stressed samples, and ACT and U-box genes were the optimal references for heat-stressed samples. TUA-1726 and U-box showed the smallest value in gene expression levels of cold treatment. The internal reference groups of the best applicability for the other samples were U-box and ACT under NaCl treatment, ACT and TUA-1726 under MV stress, HSC70 and TUB under PEG treatment, and ACT in all samples. ACT and U-box showed higher stability than the other genes based on the comprehensive stability ranking of RefFinder, as determined by the geometric mean in this study. These results will contribute to later gene expression studies in other closely related species and provide an important foundation for gene expression analysis in S. ferganica.

This paper presents a sliding mode dynamic surface control strategy for multi-machine power systems with static var compensator (SVC) to design the controller of the generator excitation system. Fi...

As soon as the play Forging the Truth (Nongzhen chengjia, 1943) written by the Chinese scholar Yang Jiang (1911-2016) premiered during World War II, critics considered the work to be the second milestone of the Chinese comedy of manners. This comment is unsurprising since Yang had a longstanding scholarly interest in the British comedy of manners tradition, especially those by Jane Austen (1775-1817). Also an academic and writer, Yang’s husband, Qian Zhongshu (1910-1998), after watching the play, began writing his only published novel, Fortress Besieged (1947). Given Qian’s inseparable fellowship with Yang Jiang, his irrefutable grounding in Chinese and European arts and letters, and exploration of how marriage impacts the individual in the novel, one wonders why scholars have not recognised even one female author among his source influences. This article establishes a link between Austen and Qian by integrating biographical accounts, a scholarship work Yang had done, and close readings of Jane Austen’s Pride and Prejudice (1813), Yang Jiang’s Nongzhen chengjia, and Qian Zhongshu’s Fortress Besieged. By looking at their adaptations of the comedy of manners genre, this article expands on a common quality the three works all share: the duality of playful irony and intelligent compassion.

Introduction: Kidney cancer is among the 10 most common cancers in both men and women. As we know, obesity and overweight is one of the confirmed risk factors. However, several studies found that overweight or obese patients with kidney cancer had a better prognosis than normal weight patients, as known as the “obesity paradox”. Therefore, in this study, we aimed to conduct a systematic meta- analysis of peer- reviewed literature to investigate the association between obesity or overweight and kidney cancer outcomes.Methods and analysis: Our review will assess case-control or cohort studies on prognosis of kidney cancer patients who are classified as obese, overweight or normal weight before 1 August 2020. Databases to be searched include PubMed/MEDLINE, Scopus, Web of Science and Embase. Two authors will independently conduct eligible studies selection process, perform data extraction and appraise the quality of included studies. Original case-control or cohort studies published in English will be considered for inclusion. The outcomes of interest will be progression-free survival, cancer- specific survival and overall survival. Meta-analyses will be performed to calculate pooled estimates. Ethics and dissemination: Our study will be based on published data, and thus there is no requirement for ethics approval. The results will be shared through publication in a peer- reviewed journal and presentations at academic conferences. PROSPERO registration number: CRD42021223347

Summary Focusing on solving the control problem of the multimachine excitation systems with static var compensator (SVC), this paper proposes a decentralized neural adaptive dynamic surface control...

The public key cryptographic algorithm SM2 is now widely used in electronic authentication systems, key management systems, and e-commercial applications systems. As an asymmetric cryptographic algorithm is based on elliptic curves cryptographic (ECC), the SM2 algorithm involves many complex calculations and is expected to be sufficiently optimized. However, we found existing SM2 implementations are less efficient due to the lack of proper optimization. In this paper, we propose Yog-SM2, an optimized implementation of SM2 digital signature algorithm, that uses features of modern desktop processors such as extended arithmetic instructions and the large cache. Yog-SM2 utilizes new features provided by modern processors to re-implement functions of big number arithmetic, prime field modular, elliptic curve point calculation, and random number generation. The use of these new hardware features significantly improves the performance of both SM2 signing and verifying. Our experiments demonstrated that the execution speed of Yog-SM2 exceeds four mainstream SM2 implementations in state-of-the-art cryptographic libraries such as OpenSSL and Intel ippcp. In addition, Yog-SM2 also achieves a better performance (97,475 sign/s and 18,870 verify/s) against the OpenSSL’s optimized implementation of ECDSA-256 (46,753 sign/s and 16,032 verify/s, OpenSSL-1.1.1b x64) on a mainstream desktop processor (Intel i7 6700, 3.4 GHz). It indicates that SM2 digital signature is promising in a widespread application scenarios.

Plants play an important role as sinks for or indicators of semivolatile organic pollutants, however most studies have focused on terrestrial plants and insufficient information has been obtained on aquatic plants to clarify the accumulation of organic pollutants via air-to-leaf vs. water-to-leaf pathways. The presence of p, pʹ-dichlorodiphenyldichloroethylene (p, pʹ-DDE), hexachlorobenzene (HCB), 15 polycyclic aromatic hydrocarbons (PAHs), and 9 substituted PAHs (s-PAHs), including oxy-PAHs and sulfur-PAHs, in 10 submerged and emergent plants collected from Lake Dianchi was analyzed in this study. Relatively low concentrations of p, pʹ-DDE (ND to 2.22 ng/g wet weight [ww]) and HCB (0.24–0.84 ng/g ww) and high levels of PAHs (46–244 ng/g ww) and s-PAHs (6.0–46.8 ng/g ww) were observed in the aquatic plants. Significantly higher concentrations of most of the compounds were detected in the leaves of the submerged plants than in those of the emergent plants. The percentages of concentration difference relative to the concentrations in the submerged plants were estimated at 55%, 40%, 10%–69% and 0.5%–79% for p, pʹ-DDE, HCB, PAHs, and s-PAHs, respectively. The percentages were found to increase significantly with an increase in log Kow, suggesting that the high level of phytoaccumulation of pollutants in aquatic plants is due to hydrophobicity-dependent diffusion via the water-to-leaf pathway and the mesophyll morphology of submerged plants.

Objective With the discovery of thermogenic adipocytes in humans, it has been hypothesized that enhancing adaptive thermogenesis may improve obesity. Although many studies have found that ginseng can improve obesity, the beneficial effects of ginsenoside Rd on obesity and its mechanisms have not been studied. Methods High-fat diet-induced obese mice were used as the study subjects, with intraperitoneal injection of Rd daily at a dose of 15 mg/kg. Body weight and energy metabolism were observed. The effects of Rd on glucose tolerance, insulin sensitivity, and cold tolerance were tested. The expression of genes associated with thermogenesis was analyzed. Finally, the mechanisms by which Rd regulates adaptive thermogenesis were studied. Results Rd ameliorated obesity and insulin resistance. Rd increased cold tolerance through enhancing thermogenic gene expression in brown adipose tissue and increased the browning of white adipose tissue induced by cold stress. Rd increased intracellular cyclic adenosine monophosphate (cAMP) content. Decreasing intracellular cAMP levels by an inhibitor of adenylyl cyclase SQ22536 abolished the promoting effects of Rd on the expression of thermogenic genes. Conclusions Rd improves obesity and insulin resistance. The upregulation of thermogenesis by Rd is dependent on the cAMP/protein kinase A signaling pathway.

// Ling Qi 1,* , Lijuan Ding 2,* , Shuran Wang 3 , Yue Zhong 3 , Donghai Zhao 3 , Ling Gao 2 , Weiyao Wang 1 , Peng Lv 1 , Ye Xu 1 and Shudong Wang 4 1 Basic Medical College, Jilin Medical University, Jilin, China 2 Department of Radiation Oncology, First Hospital of Jilin University, Changchun, China 3 Department of Science and Technology, Jilin Medical University, Jilin, China 4 Center of Cardiovascular Diseases, First Hospital of Jilin University, Changchun, China * These authors have contributed equally to this work Correspondence to: Ye Xu, email: // Shudong Wang, email: // Keywords : chemotherapy, radiotherapy, glioma, network meta-analysis, temozolomide Received : April 05, 2016 Accepted : July 10, 2016 Published : July 21, 2016 Abstract Different chemotherapy drugs are generally introduced in clinical practices combining with therapy for glioma treatment. However, these chemotherapy drugs have rarely been compared with each other and the optimum drug still remains to be proved. In this research, medical databases were consulted, PubMed, Embase and Cochrane Library included. As primary outcomes, hazard ratio (HR) of overall survival (OS) and progression-free survival (PFS) with their corresponding 95% credential intervals ( CrI ) were reported. A network meta-analysis was conducted; the surface under the cumulative ranking curve (SUCRA) was utilized for treatment rank and a cluster analysis based on SUCRA values was performed. This research includes 14 trials with 3,681 subjects and eight interventions. In terms of network meta-analysis, placebo was proved to be inferior to the combination of temozolomide (TMZ), nimustine (ACNU) and cisplatin (CDDP). Also, bevacizumab (BEV) in conjunction with TMZ were significantly more effective than placebo with an HR of 0.40. The estimated probabilities from SUCRA verified the above outcomes, confirming that the combination of TMZ, ACNU and CDDP exhibited the highest ranking probability of 0.889 with respect to OS, while BEV in combination with TMZ - with a probability of 0.772 - ranked the first place with respect to PFS. According to the results of this network meta-analysis, the combination of (1) TMZ, ACNU and CDDP; (2) BEV in combination with TMZ and (3) cilengitide in combination with TMZ, are considered as the preferable choices of chemotherapy drugs for glioma treatment.

Habitat is of great importance in determining the trophic transfer of pollutants in freshwater ecosystems; however, the major factors influencing chemical trophodynamics in pelagic and benthic food webs remain unclear. This study investigated the levels of p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE), polycyclic aromatic hydrocarbons (PAHs), and substituted PAHs (s-PAHs) in 2 plankton species, 6 invertebrate species, and 10 fish species collected from Lake Dianchi in southern China. Relatively high concentrations of PAHs and s-PAHs were detected with total concentrations of 11.4-1400 ng/g wet weight (ww) and 5.3-115 ng/g ww, respectively. Stable isotope analysis and stomach content analysis were applied to quantitatively determine the trophic level of individual organisms and discriminate between pelagic and benthic pathways, and the trophodynamics of the detected compounds in the two food webs were assessed. P,p'-DDE was found to exhibit relatively higher trophic magnification rate in the pelagic food web than in the benthic food web. In contrast, PAHs and s-PAHs exhibited greater dilution rates along the trophic levels in the pelagic food web. The lower species differences of pollutants accumulated in benthic organisms compared to pelagic organisms is attributable to extra uptake via ingested sediment in benthos. The average uptake proportions of PAHs and s-PAHs via ingested sediment in benthic biotas were estimated to be 31-77%, and that of p,p'-DDE was 46%. The uptake routes are of importance for assessing the trophic magnification potentials of organic pollutants, especially in eutrophic freshwater ecosystems.

To realize the oxidative damage of kidney mitochondrial complex in obese rats induced by high-fat diet and investigate the protective effects of sulforaphane against the damage.Eighty-eight adult male SD rats were used, after 1 week adaptability feeding, 8 rats were selected as control group and given low-fat diet. The other 80 rats were given high-fat diet. After 2 weeks, the 32 diet-induced obesity models were choosen whose weight gain was higher than 40%. The 32 rats were randomly divided into 4 groups, i.e. high fat group, high fat+sulforaphane low dose group, high fat+sulforaphane middle dose group and high fat+sulforaphane high dose group. The rats in the sulforaphane low, middle and high dose groups were orally administered with sulforaphane 5, 10 and 20 mg/kg, all the 4 groups were kept feeding high-fat diet for 5 weeks. All rats were sacrificed and their kidneys were removed to assay the index of oxidative damages.The content of ROS (0.26 ± 0.04) and MDA((0.87 ± 0.05) U/mg) in the hight-fat group were significantly higher than those in the control group((0.20 ± 0.02),(0.57 ± 0.08) U/mg)(t values were -3.02 and -4.72, P0.05). The activity of T-AOC((0.43 ± 0.04) U/mg) and MMP (12.09 ± 1.56) were lower than the control group ((0.48 ± 0.04 U/mg, (16.08 ± 3.12) )(t values were 2.06 and 2.28, P0.05). Gavage intervention with sulforaphane, the MDA amount ((0.67 ± 0.05), (0.55 ± 0.05), (0.56 ± 0.07) U/mg) in the sulforaphane low, middle and high dose groups were lower than the hight-fat group ((0.87 ± 0.05) U/mg (t values were 3.65, 5.71 and 5.60. P0.05). The activity of T-AOC ((0.49 ± 0.05), (0.55 ± 0.05), (0.54 ± 0.04) U/mg), T-SOD ((61.07 ± 2.79), (55.95 ± 2.39), (60.26 ± 6.02) U/mg) and the level of MMP ((17.17 ± 2.52), (18.24 ± 2.54), (18.21 ± 3.65)) were higher than in the high-fat group ((0.43 ± 0.04) U/mg,(47.22 ± 2.43) U/mg,(12.09 ± 1.56)) (tT-AOC values were -2.36, -4.83 and -4.30; tT-SOD values were -6.37, -4.71 and -5.99; tMMP values were -2.90, -3.52 and -3.50, P0.05). The activity of GSH-Px in the sulforaphane low and middle dose groups ((69.12 ± 8.63), (64.43 ± 6.58) U/mg) were higher than those in the high-fat group((53.03 ± 5.70) U/mg)(t values were -3.82 and -2.71, P0.05). But there were no significant difference between the high dose group ((60.02 ± 7.05) U/mg) and the high-fat group (t = -1.66, P0.05).High-fat diet can induce the mitochondrial oxidative dysfunction in kidney, and sulforaphane shows protective effect on the kidney mitochondrial complex from oxidative damage in obese rats induced by high-fat diet.