509 results on '"Silke, John"'
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2. Brief Notices
3. RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation
4. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency
5. Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
6. The Celtic Monk: Rules and Writings of Early Irish Monks by Uinseann Ó Maidín, O.C.R. (review)
7. Priests and Prelates of Armagh in the Age of Reformations, 1518-1558 by Henry A. Jefferies (review)
8. The Cistercian Abbeys of Tipperary by Colmcille Ó Conbhuidhe, OCSO (review)
9. Blocking cell death limits lung damage and inflammation from influenza
10. RIPK1 and necroptosis role in premature ageing
11. A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
12. The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family
13. Apoptotic cell death in disease—Current understanding of the NCCD 2023
14. MLKL deficiency protects against low-grade, sterile inflammation in aged mice
15. High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell death
16. Deletion of Gpatch2 does not alter Tnf expression in mice
17. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
18. OXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling
19. Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
20. Dual roles for LUBAC signaling in thymic epithelial cell development and survival
21. Unleashing TNF cytotoxicity to enhance cancer immunotherapy
22. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL
23. Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models
24. Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1−/− mice
25. Telemedical cardiac risk assessment by implantable cardiac monitors in patients after myocardial infarction with autonomic dysfunction (SMART-MI-DZHK9): a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial
26. Single-cell spatial proteomics identifies the JAK/STAT pathway as an actionable therapeutic target in lethal cutaneous drug reactions
27. cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation
28. OR05-06 Histone Deacetylase Inhibitor, Panobinostat, In Combination With A Smac-mimetic For The Treatment Of Ovarian Granulosa Cell Tumours
29. Targeting triple-negative breast cancers with the Smac-mimetic birinapant
30. Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease
31. Biallelic human SHARPINloss of function induces autoinflammation and immunodeficiency
32. IAPs and Cell Death
33. The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis
34. The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
35. Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation
36. Figure S2 from Combined PPARγ Activation and XIAP Inhibition as a Potential Therapeutic Strategy for Ovarian Granulosa Cell Tumors
37. Movie 1 from Antagonism of IAPs Enhances CAR T-cell Efficacy
38. Data from Antagonism of IAPs Enhances CAR T-cell Efficacy
39. Supplementary Figures 1 and 2 from Antagonism of IAPs Enhances CAR T-cell Efficacy
40. Supplementary Data Legends from Antagonism of IAPs Enhances CAR T-cell Efficacy
41. Table S1 from Combined PPARγ Activation and XIAP Inhibition as a Potential Therapeutic Strategy for Ovarian Granulosa Cell Tumors
42. Movie 2 from Antagonism of IAPs Enhances CAR T-cell Efficacy
43. Data from Combined PPARγ Activation and XIAP Inhibition as a Potential Therapeutic Strategy for Ovarian Granulosa Cell Tumors
44. Engineered Exosomes as Vehicles for Biologically Active Proteins
45. ‘Did He Who Made the Lamb Make Thee?’ New Developments in Treating the ‘Fearful Symmetry’ of Acute Myeloid Leukemia
46. MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
47. A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
48. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
49. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
50. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
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