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1. Heterogeneous melting near the Thwaites Glacier grounding line

Author

Schmidt, BE, Washam, P, Davis, PED, Nicholls, KW, Holland, DM, Lawrence, JD, Riverman, KL, Smith, JA, Spears, A, Dichek, DJG, Mullen, AD, Clyne, E, Yeager, B, Anker, P, Meister, MR, Hurwitz, BC, Quartini, ES, Bryson, FE, Basinski-Ferris, A, Thomas, C, Wake, J, Vaughan, DG, Anandakrishnan, S, Rignot, E, Paden, J, and Makinson, K

Subjects
Earth Sciences, Oceanography, Physical Geography and Environmental Geoscience, Geology, Climate Action, General Science & Technology
Abstract

Thwaites Glacier represents 15% of the ice discharge from the West Antarctic Ice Sheet and influences a wider catchment1-3. Because it is grounded below sea level4,5, Thwaites Glacier is thought to be susceptible to runaway retreat triggered at the grounding line (GL) at which the glacier reaches the ocean6,7. Recent ice-flow acceleration2,8 and retreat of the ice front8-10 and GL11,12 indicate that ice loss will continue. The relative impacts of mechanisms underlying recent retreat are however uncertain. Here we show sustained GL retreat from at least 2011 to 2020 and resolve mechanisms of ice-shelf melt at the submetre scale. Our conclusions are based on observations of the Thwaites Eastern Ice Shelf (TEIS) from an underwater vehicle, extending from the GL to 3 km oceanward and from the ice-ocean interface to the sea floor. These observations show a rough ice base above a sea floor sloping upward towards the GL and an ocean cavity in which the warmest water exceeds 2 °C above freezing. Data closest to the ice base show that enhanced melting occurs along sloped surfaces that initiate near the GL and evolve into steep-sided terraces. This pronounced melting along steep ice faces, including in crevasses, produces stratification that suppresses melt along flat interfaces. These data imply that slope-dependent melting sculpts the ice base and acts as an important response to ocean warming.

Published
2023

2. Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

Author

Liang, J, Le, TH, Velez Edwards, DR, Tayo, BO, Gaulton, KJ, Smith, JA, Lu, Y, Jensen, RA, Chen, G, Yanek, LR, Schwander, K, Tajuddin, SM, Sofer, T, Kim, W, Kayima, J, McKenzie, CA, Fox, E, Nalls, MA, Young, JH, Sun, YV, Lane, JM, Cechova, S, Zhou, J, Tang, H, Fornage, M, Musani, SK, Wang, H, Lee, J, Adeyemo, A, Dreisbach, AW, Forrester, T, Chu, P-L, Cappola, A, Evans, MK, Morrison, AC, Martin, LW, Wiggins, KL, Hui, Q, Zhao, W, Jackson, RD, Ware, EB, Faul, JD, Reiner, AP, Bray, M, Denny, JC, Mosley, TH, Palmas, W, Guo, X, Papanicolaou, GJ, Penman, AD, Polak, JF, Rice, K, Taylor, KD, Boerwinkle, E, Bottinger, EP, Liu, K, Risch, N, Hunt, SC, Kooperberg, C, Zonderman, AB, Laurie, CC, Becker, DM, Cai, J, Loos, RJF, Psaty, BM, Weir, DR, Kardia, SLR, Arnett, DK, Won, S, Edwards, TL, Redline, S, Cooper, RS, Rao, DC, Rotter, JI, Rotimi, C, Levy, D, Chakravarti, A, Zhu, X, and Franceschini, N

Abstract

[This corrects the article DOI: 10.1371/journal.pgen.1006728.].

Published
2018

3. GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Author

Ibrahim-Verbaas, CA, Bressler, J, Debette, S, Schuur, M, Smith, AV, Bis, JC, Davies, G, Trompet, S, Smith, JA, Wolf, C, Chibnik, LB, Liu, Y, Vitart, V, Kirin, M, Petrovic, K, Polasek, O, Zgaga, L, Fawns-Ritchie, C, Hoffmann, P, Karjalainen, J, Lahti, J, Llewellyn, DJ, Schmidt, CO, Mather, KA, Chouraki, V, Sun, Q, Resnick, SM, Rose, LM, Oldmeadow, C, Stewart, M, Smith, BH, Gudnason, V, Yang, Q, Mirza, SS, Jukema, JW, deJager, PL, Harris, TB, Liewald, DC, Amin, N, Coker, LH, Stegle, O, Lopez, OL, Schmidt, R, Teumer, A, Ford, I, Karbalai, N, Becker, JT, Jonsdottir, MK, Au, R, Fehrmann, RSN, Herms, S, Nalls, M, Zhao, W, Turner, ST, Yaffe, K, Lohman, K, van Swieten, JC, Kardia, SLR, Knopman, DS, Meeks, WM, Heiss, G, Holliday, EG, Schofield, PW, Tanaka, T, Stott, DJ, Wang, J, Ridker, P, Gow, AJ, Pattie, A, Starr, JM, Hocking, LJ, Armstrong, NJ, McLachlan, S, Shulman, JM, Pilling, LC, Eiriksdottir, G, Scott, RJ, Kochan, NA, Palotie, A, Hsieh, Y-C, Eriksson, JG, Penman, A, Gottesman, RF, Oostra, BA, Yu, L, DeStefano, AL, Beiser, A, Garcia, M, Rotter, JI, Nöthen, MM, Hofman, A, Slagboom, PE, Westendorp, RGJ, Buckley, BM, Wolf, PA, Uitterlinden, AG, Psaty, BM, Grabe, HJ, Bandinelli, S, and Chasman, DI

Subjects
Biological Psychology, Clinical and Health Psychology, Psychology, Human Genome, Neurosciences, Genetics, Clinical Research, Aging, Aetiology, 2.1 Biological and endogenous factors, Aged, Aged, 80 and over, Cell Adhesion Molecules, Cognition, Cohort Studies, Executive Function, Female, Genetic Association Studies, Genetic Variation, Genome-Wide Association Study, Genomics, Humans, Introns, Male, Middle Aged, Neuropsychological Tests, Polymorphism, Single Nucleotide, White People, gamma-Aminobutyric Acid, Generation Scotland, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Clinical sciences, Biological psychology, Clinical and health psychology
Abstract

To identify common variants contributing to normal variation in two specific domains of cognitive functioning, we conducted a genome-wide association study (GWAS) of executive functioning and information processing speed in non-demented older adults from the CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) consortium. Neuropsychological testing was available for 5429-32,070 subjects of European ancestry aged 45 years or older, free of dementia and clinical stroke at the time of cognitive testing from 20 cohorts in the discovery phase. We analyzed performance on the Trail Making Test parts A and B, the Letter Digit Substitution Test (LDST), the Digit Symbol Substitution Task (DSST), semantic and phonemic fluency tests, and the Stroop Color and Word Test. Replication was sought in 1311-21860 subjects from 20 independent cohorts. A significant association was observed in the discovery cohorts for the single-nucleotide polymorphism (SNP) rs17518584 (discovery P-value=3.12 × 10(-8)) and in the joint discovery and replication meta-analysis (P-value=3.28 × 10(-9) after adjustment for age, gender and education) in an intron of the gene cell adhesion molecule 2 (CADM2) for performance on the LDST/DSST. Rs17518584 is located about 170 kb upstream of the transcription start site of the major transcript for the CADM2 gene, but is within an intron of a variant transcript that includes an alternative first exon. The variant is associated with expression of CADM2 in the cingulate cortex (P-value=4 × 10(-4)). The protein encoded by CADM2 is involved in glutamate signaling (P-value=7.22 × 10(-15)), gamma-aminobutyric acid (GABA) transport (P-value=1.36 × 10(-11)) and neuron cell-cell adhesion (P-value=1.48 × 10(-13)). Our findings suggest that genetic variation in the CADM2 gene is associated with individual differences in information processing speed.

Published
2016

5. Diet, Diabetes Status, and Personal Experiences of Individuals with Type 2 diabetes Who Self-Selected and Followed a Low Carbohydrate High Fat diet

Author

Webster CC, Murphy TE, Larmuth KM, Noakes TD, and Smith JA

Subjects
carbohydrate restriction, diabetes remission, ketogenic diet, lchf, nutritional therapy, food addiction, Specialties of internal medicine, RC581-951
Abstract

Christopher C Webster, Tamzyn E Murphy, Kate M Larmuth, Timothy D Noakes, James A Smith Division of Exercise Science and Sports Medicine, University of Cape Town, Cape Town, South AfricaCorrespondence: Christopher C WebsterDivision of Exercise Science and Sports Medicine, University of Cape Town, Sports Science Institute of South Africa, Newlands, Cape Town 7700, South AfricaEmail wbschr002@myuct.ac.zaBackground: Low carbohydrate high fat (LCHF) diets are increasing in popularity amongst patients with type 2 diabetes (T2D), however it is unclear what constitutes a sustainable LCHF diet in a real-world setting.Methods: This descriptive multi-method study characterized the diets, T2D status, and personal experiences of individuals with T2D who claimed to have followed an LCHF diet for at least 6 months. Participants completed a medications history, mixed-method dietary assessment, provided a blood sample, and were interviewed in-depth about their experiences with the diet (First-Assessment). Past medical records were obtained corresponding to T2D diagnosis and prior to starting their LCHF diets. Additionally, participants were followed up 15 months later to assess T2D remission (Follow-Up).Results: Twenty-eight participants completed First-Assessment and 24 completed Follow-Up. Habitual carbohydrate intake was 20 to 50 g/d for 10 participants and 50 to 115 g/d for 17 participants. Commonly reported foods were full-fat dairy, non-starchy vegetables, coconut oil, eggs, nuts, olives and avocados, olive oil, and red meat and poultry with fat. Median (interquartile range) for HbA1c was 7.5 (6.5–9.5) % prior to starting their diets, 5.8 (5.4–6.2) % at First-Assessment and 5.9 (5.3–6.6) % at Follow-Up. Reported body weight and glucose-lowering medication requirements were considerably lower at both assessments than when starting the diet. At Follow-Up, 24 participants had been following their LCHF diets for 35 (26–53) months, the majority of which were in full or partial T2D remission. Participants perceived reduced hunger and cravings as one of the most important aspects of their diets. Of concern, many participants felt unsupported by their doctors.Conclusion: This study described the foods and characteristics of an LCHF “lifestyle” that was sustainable and effective for certain T2D patients in a real-world setting.Keywords: carbohydrate restriction, diabetes remission, ketogenic diet, LCHF, nutritional therapy, food addiction

Published
2019

6. Prolonged survival in patients >= 60 years with first relapsed/refractory acute myeloid leukemia treated with vosaroxin plus cytarabine vs placebo plus cytarabine: Results from the phase 3 VALOR study

Author

Krug, U, Ravandi, F, Ritchie, EK, Sayar, H, Lancet, JE, Craig, MD, Vey, N, Strickland, SA, Schiller, GJ, Jabbour, E, Erba, HP, Pigneux, A, Horst, H-A, Recher, C, Klimek, VM, Cortes, J, Roboz, GJ, Craig, AR, Fox, JA, Ward, R, Smith, JA, Acton, G, Mehta, C, Kantarjian, HM, and Stuart, RK

Published
2015

7. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

Author

Davies, G, Armstrong, N, Bis, JC, Bressler, J, Chouraki, V, Giddaluru, S, Hofer, E, Ibrahim-Verbaas, CA, Kirin, M, Lahti, J, van der Lee, SJ, Le Hellard, S, Liu, T, Marioni, RE, Oldmeadow, C, Postmus, I, Smith, AV, Smith, JA, Thalamuthu, A, Thomson, R, Vitart, V, Wang, J, Yu, L, Zgaga, L, Zhao, W, Boxall, R, Harris, SE, Hill, WD, Liewald, DC, Luciano, M, Adams, H, Ames, D, Amin, N, Amouyel, P, Assareh, AA, Au, R, Becker, JT, Beiser, A, Berr, C, Bertram, L, Boerwinkle, E, Buckley, BM, Campbell, H, Corley, J, De Jager, PL, Dufouil, C, Eriksson, JG, Espeseth, T, Faul, JD, Ford, I, Generation Scotland, Gottesman, RF, Griswold, ME, Gudnason, V, Harris, TB, Heiss, G, Hofman, A, Holliday, EG, Huffman, J, Kardia, SLR, Kochan, N, Knopman, DS, Kwok, JB, Lambert, J-C, Lee, T, Li, G, Li, S-C, Loitfelder, M, Lopez, OL, Lundervold, AJ, Lundqvist, A, Mather, KA, Mirza, SS, Nyberg, L, Oostra, BA, Palotie, A, Papenberg, G, Pattie, A, Petrovic, K, Polasek, O, Psaty, BM, Redmond, P, Reppermund, S, Rotter, JI, Schmidt, H, Schuur, M, Schofield, PW, Scott, RJ, Steen, VM, Stott, DJ, van Swieten, JC, Taylor, KD, Trollor, J, Trompet, S, Uitterlinden, AG, Weinstein, G, Widen, E, Windham, BG, Jukema, JW, and Wright, AF

Subjects
Generation Scotland, Humans, Genetic Predisposition to Disease, HMGN1 Protein, Cohort Studies, Cognition, Cognition Disorders, Neuropsychological Tests, Phenotype, Polymorphism, Single Nucleotide, Aged, Aged, 80 and over, Middle Aged, Scotland, Female, Male, Atherosclerosis, Genome-Wide Association Study, and over, Polymorphism, Single Nucleotide, Psychiatry, Biological Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences
Abstract

General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait in middle-aged and older adults. We conducted a meta-analysis of genome-wide association studies of 31 cohorts (N=53,949) in which the participants had undertaken multiple, diverse cognitive tests. A general cognitive function phenotype was tested for, and created in each cohort by principal component analysis. We report 13 genome-wide significant single-nucleotide polymorphism (SNP) associations in three genomic regions, 6q16.1, 14q12 and 19q13.32 (best SNP and closest gene, respectively: rs10457441, P=3.93 × 10(-9), MIR2113; rs17522122, P=2.55 × 10(-8), AKAP6; rs10119, P=5.67 × 10(-9), APOE/TOMM40). We report one gene-based significant association with the HMGN1 gene located on chromosome 21 (P=1 × 10(-6)). These genes have previously been associated with neuropsychiatric phenotypes. Meta-analysis results are consistent with a polygenic model of inheritance. To estimate SNP-based heritability, the genome-wide complex trait analysis procedure was applied to two large cohorts, the Atherosclerosis Risk in Communities Study (N=6617) and the Health and Retirement Study (N=5976). The proportion of phenotypic variation accounted for by all genotyped common SNPs was 29% (s.e.=5%) and 28% (s.e.=7%), respectively. Using polygenic prediction analysis, ~1.2% of the variance in general cognitive function was predicted in the Generation Scotland cohort (N=5487; P=1.5 × 10(-17)). In hypothesis-driven tests, there was significant association between general cognitive function and four genes previously associated with Alzheimer's disease: TOMM40, APOE, ABCG1 and MEF2C.

Published
2015

9. Elevated fractional exhaled nitric oxide and blood eosinophil counts are associated with a 17q21 asthma risk allele in adult subjects

Author

Schwantes EA, Evans MD, Cuskey A, Burford A, Smith JA, Lemanske RF Jr, Jarjour NN, and Mathur SK

Subjects
asthma, eosinophils, exhaled nitric oxide (FeNO), 17q21, Immunologic diseases. Allergy, RC581-607
Abstract

Elizabeth A Schwantes,1 Michael D Evans,2 Alex Cuskey,1 Alex Burford,1 Judith A Smith,3 Robert F Lemanske Jr,3 Nizar N Jarjour,1 Sameer K Mathur1 1Division of Allergy, Pulmonary and Critical Care, Department of Medicine, 2Department of Biostatistics and Medical Informatics, 3Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA Background and objectives: Genome-wide association studies identified single-nucleotide polymorphisms (SNPs) at the 17q21 locus conferring increased risk for childhood-onset asthma. Little is known about how these SNPs impact adult asthma patients. We sought to examine an adult population for associations between rs7216389 (17q21-associated SNP) and features of asthma including fractional exhaled nitric oxide (FeNO), eosinophil counts, and age of asthma onset. Methods: Subjects were genotyped at SNP rs7216389. The geometric mean of FeNO measurements and peripheral blood eosinophil counts from 2008 to 2015 were collected. Demographics and medical history were collected including self-reported allergy diagnoses and age of asthma onset. Eosinophils, monocytes, and peripheral blood mononuclear cells (PBMCs) were isolated for the examination of ORMDL3 expression. Results: FeNO levels from 157 genotyped subjects (31CC, 72CT, and 54TT) and peripheral eosinophil counts from 252 genotyped subjects (46CC, 122CT, and 84TT) were analyzed. In a sub-group analysis of asthma subjects, the number of attributable T alleles was associated with significantly lower age of asthma onset (P=0.03) and greater FeNO levels (geometric mean 30.0 ppb TT, 20.0 ppb CT, 20.0 ppb CC, P=0.02). In the total cohort of subjects, the T allele was associated with a higher percentage of individual eosinophil counts >200/mm3 (45% TT, 26% CT, 24% CC, P=0.005). Eosinophils expressed ORMDL3 mRNA and protein. Conclusion: In adult subjects, the number of T alleles at SNP rs7216389 corresponds to significantly greater FeNO levels and peripheral eosinophil counts. The expression of ORMDL3 in eosinophils suggests that they may participate in mediating the asthma risk associated with the 17q21 locus. Keywords: asthma, eosinophils, fractional exhaled nitric oxide, 17q21

Published
2017

10. Controlling anisotropic properties by manipulating the orientation of chiral small molecules

Author

Wade, J, Salerno, F, Kilbride, RC, Kim, DK, Schmidt, JA, Smith, JA, LeBlanc, LM, Wolpert, EH, Adeleke, AA, Johnson, ER, Nelson, J, Mori, T, Jelfs, KE, Heutz, S, and Fuchter, MJ

Subjects
General Chemical Engineering, Anisotropy, Electrons, General Chemistry
Abstract

Chiral π-conjugated molecules bring new functionality to technological applications and represent an exciting, rapidly expanding area of research. Their functional properties, such as the absorption and emission of circularly polarized light or the transport of spin-polarized electrons, are highly anisotropic. As a result, the orientation of chiral molecules critically determines the functionality and efficiency of chiral devices. Here we present a strategy to control the orientation of a small chiral molecule (2,2'-dicyano[6]helicene) by the use of organic and inorganic templating layers. Such templating layers can either force 2,2'-dicyano[6]helicene to adopt a face-on orientation and self-assemble into upright supramolecular columns oriented with their helical axis perpendicular to the substrate, or an edge-on orientation with parallel-lying supramolecular columns. Through such control, we show that low- and high-energy chiroptical responses can be independently 'turned on' or 'turned off'. The templating methodologies described here provide a simple way to engineer orientational control and, by association, anisotropic functional properties of chiral molecular systems for a range of emerging technologies.

Published
2022

11. Open-circuit and short-circuit loss management in wide-gap perovskite p-i-n solar cells

Author

Caprioglio, P, Smith, JA, Oliver, RDJ, Dasgupta, A, Choudhary, S, Farrar, MD, Ramadan, AJ, Lin, Y-H, Christoforo, MG, Ball, JM, Diekmann, J, Thiesbrummel, J, Zaininger, K-A, Shen, X, Johnston, MB, Neher, D, Stolterfoht, M, and Snaith, HJ

Subjects
Multidisciplinary, General Physics and Astronomy, General Chemistry, General Biochemistry, Genetics and Molecular Biology
Abstract

In this work, we couple theoretical and experimental approaches to understand and reduce the losses of wide bandgap Br-rich perovskite pin devices at open-circuit voltage (VOC) and short-circuit current (JSC) conditions. A mismatch between the internal quasi-Fermi level splitting (QFLS) and the external VOC is detrimental for these devices. We demonstrate that modifying the perovskite top-surface with guanidinium-Br and imidazolium-Br forms a low-dimensional perovskite phase at the n-interface, suppressing the QFLS-VOC mismatch, and boosting the VOC. Concurrently, the use of an ionic interlayer or a self-assembled monolayer at the p-interface reduces the inferred field screening induced by mobile ions at JSC, promoting charge extraction and raising the JSC. The combination of the n- and p-type optimizations allows us to approach the thermodynamic potential of the perovskite absorber layer, resulting in 1 cm2 devices with performance parameters of VOCs up to 1.29 V, fill factors above 80% and JSCs up to 17 mA/cm2, in addition to a thermal stability T80 lifetime of more than 3500 h at 85 °C.

Published
2023

12. Enhancing health and independent living for veterans with disabilities by leveraging community-based resources

Author

Hale-Gallardo J, Jia H, Delisle T, Levy CE, Osorio V, Smith JA, and Hannold EM

Subjects
independent living, veterans, disabilities, community, Medicine (General), R5-920
Abstract

Jennifer Hale-Gallardo,1 Huanguang Jia,1 Tony Delisle,2 Charles E Levy,1,3–5 Valentina Osorio,1 Jennifer A Smith,1 Elizabeth M Hannold,1,† 1Center of Innovation on Disability and Rehabilitation Research, North Florida/South Georgia Veterans Health System, 2Center for Independent Living of North Central Florida, 3Physical Medicine and Rehabilitation Service, North Florida/South Georgia Veterans Health Service, 4The Department of Occupational Therapy, College of Public Health and Health Professions, 5The Center for the Arts in Medicine, College of the Arts, University of Florida, Gainesville, FL, USA †Elizabeth M Hannold passed away on September 28, 2015. Abstract: The number of US veterans with disabilities has increased in recent years as service members have returned home with extensive injuries and veterans from previous wars acquire functional limitations as a consequence of aging with chronic diseases. Veterans with severe disabilities need assistance and support to maintain independence at home and to avoid institutionalization. The US Department of Veterans Affairs (VA) strives to network with community organizations to achieve the best possible outcomes for veterans. Key community resources in the US for individuals with disabilities are Centers for Independent Living (CILs) that provide a wide range of services, promoting independent living and well-being for people across disabilities. The widespread availability and services of CILs nationwide suggest their potential as a community-based resource for veterans, particularly for those with limited access to VA care. In this article, we discuss long-term needs of veterans with disabilities, efforts to address veterans’ rehabilitation needs at the VA and opportunities for leveraging the strengths of community-based organizations for veterans. More research is warranted to investigate CIL services and potential for CIL–VA partnerships. Keywords: rehabilitation, community engagement, community reintegration, functional limitations

Published
2017

14. Proactive breast cancer risk assessment in primary care: a review based on the principles of screening.

Author

Usher-Smith, JA, Hindmarch, S, French, DP, Tischkowitz, M, Moorthie, S, Walter, FM, Dennison, RA, Stutzin Donoso, F, Archer, S, Taylor, L, Emery, J, Morris, S, Easton, DF, Antoniou, AC, Usher-Smith, JA, Hindmarch, S, French, DP, Tischkowitz, M, Moorthie, S, Walter, FM, Dennison, RA, Stutzin Donoso, F, Archer, S, Taylor, L, Emery, J, Morris, S, Easton, DF, and Antoniou, AC

Abstract

In the UK, the National Institute for Health and Care Excellence (NICE) recommends that women at moderate or high risk of breast cancer be offered risk-reducing medication and enhanced breast screening/surveillance. In June 2022, NICE withdrew a statement recommending assessment of risk in primary care only when women present with concerns. This shift to the proactive assessment of risk substantially changes the role of primary care, in effect paving the way for a primary care-based screening programme to identify those at moderate or high risk of breast cancer. In this article, we review the literature surrounding proactive breast cancer risk assessment within primary care against the consolidated framework for screening. We find that risk assessment for women under 50 years currently satisfies many of the standard principles for screening. Most notably, there are large numbers of women at moderate or high risk currently unidentified, risk models exist that can identify those women with reasonable accuracy, and management options offer the opportunity to reduce breast cancer incidence and mortality in that group. However, there remain a number of uncertainties and research gaps, particularly around the programme/system requirements, that need to be addressed before these benefits can be realised.

Published
2023

18. Seed banks, community dynamics and species persistence in 5 Tasmanian temporary wetlands

Author

Smith, JA

Subjects
Biogeography and phylogeography
Abstract

Water regime has been found to be the most important factor in determining vegetation patterns in wetlands. The present study investigates the short and long-term persistence of plant communities within 5 temporary Tasmanian lentic wetlands and- resistance and resilience of wetland communities to dry periods. Within each wetland an aquatic herbaceous and sedge-dominated zone were sampled seasonally between February, 1997 and November, 1998, to test difference between and within wetlands, and their relations to water depth. Four glasshouse experiments using sediments taken from 9 permanent quadrats per vegetation type per wetland (zone) were used to determine temporal and spatial differences in seed banks in relation to season, vegetation type, depth, germination treatment and water regime. The relationship between the seed bank and extant vegetation was investigated. A functional group classification generated similar groups to Brock and Casanova (1997). These were: a) submerged; b) amphibious fluctuation responder; c) amphibious fluctuation tolerator-emergent; d) amphibious fluctuation tolerator-saturated/mudflat; and e) terrestrial. The vegetation communities within the 5 temporary wetlands proved not resistant to changes in water level. Large differences in percentage cover were associated with hydrological changes over the 2 year period. However, the communities were able to resurrect relatively quickly after both short and long term dry periods. The seed bank experiments indicated that Tasmanian temporary wetlands have speciesrich persistent seed banks, and, therefore, the potential for future regeneration. In general, species in the seed bank could be related to species found in the extant vegetation. However, at any given time, species can be found in the seed bank and not present in the extant vegetation, or vice versa. Both seed banks and vegetative regeneration were important mechanisms for species persistence in the vegetation communities of the 5 wetlands.

Published
2023
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19. Validation and Meaningful Change Thresholds for an Objective Cough Frequency Measurement in Chronic Cough

Author

Smith, Jaclyn, Schelfhout, J, Nguyen, AM, Birring, SS, Bacci, ED, Vernon, M, Muccino, DR, La, Rosa C, and Smith, JA

Subjects
Pulmonary and Respiratory Medicine, Clinically meaningful change, Patient-reported outcomes, Cough, ROC Curve, Objective cough frequency, Chronic cough, Cough monitoring, Humans, Patient Reported Outcome Measures, Plastic Surgery Procedures, Pain Measurement, Cough severity
Abstract

Purpose Objective cough frequency is used to assess efficacy of chronic cough (CC) treatments. The objective of this study was to explore the relationship between objective cough frequency and cough-specific patient-reported outcomes (PROs) and estimate a clinically meaningful change threshold (MCT) for objective cough frequency. Methods Data collected in a phase 2b study in participants with refractory or unexplained CC were used to investigate the relationship between 24-h cough frequency (measured using an ambulatory cough monitor) and cough-specific PROs (i.e., cough severity visual analog scale, cough severity diary, Leicester Cough Questionnaire). Convergent validity was assessed using Spearman ρ. An MCT for 24-h cough frequency was estimated using the patient global impression of change (PGIC) scale as an anchor. Results Correlations between 24-h cough frequency and cough-specific PROs at baseline, Week 4, and Week 12 were significant (P ρ = 0.30–0.58). Participants categorized as very much improved/much improved (i.e., PGIC of 1 or 2) or minimally improved (i.e., PGIC of 3) had mean 24-h cough frequency reductions of 55% and 30%, respectively. Receiver operating characteristic curve analysis suggested that a 24-h cough frequency reduction of 38% optimizes sensitivity and specificity for predicting a PGIC score of 1–3. Conclusion Objective 24-h cough frequency is significantly associated with cough-specific PROs, but cough frequency and PROs most likely capture distinct aspects of CC. A ≥ 30% reduction in 24-h cough frequency is a reasonable MCT to define treatment response in CC clinical trials.

Published
2022

20. Synergistic Surface Modification of Tin-Lead Perovskite Solar Cells

Author

Hu, S, Zhao, P, Nakano, K, Oliver, RDJ, Pascual, J, Smith, JA, Yamada, T, Truong, MA, Murdey, R, Shioya, N, Hasegawa, T, Ehara, M, Johnston, MB, Tajima, K, Kanemitsu, Y, Snaith, HJ, and Wakamiya, A

Subjects
Mechanics of Materials, Mechanical Engineering, General Materials Science
Abstract

Interfaces in thin-film photovoltaics play a pivotal role in determining device efficiency and longevity. Herein, we study the top surface treatment of mixed tin-lead (∼1.26 eV) halide perovskite films for p-i-n solar cells. We are able to promote charge extraction by treating the perovskite surface with piperazine. This compound reacts with the organic cations at the perovskite surface, modifying the surface structure and tuning the interfacial energy level alignment. In addition, the combined treatment with C60 pyrrolidine tris-acid (CPTA) reduces hysteresis and leads to efficiencies up to 22.7%, with open-circuit voltage values reaching 0.90 V, ∼92% of the radiative limit for the band gap of this material. The modified cells also show superior stability, with unencapsulated cells retaining 96% of their initial efficiency after >2000 hours of storage in N2 and encapsulated cells retaining 90% efficiency after >450 hours of storage in air. Intriguingly, CPTA preferentially binds to Sn2+ sites at film surface over Pb2+ due to the energetically favoured exposure of the former, according to first-principles calculations. This work provides new insights into the surface chemistry of perovskite films in terms of their structural, electronic, and defect characteristics and we use this knowledge to fabricate state-of-the-art solar cells.

Published
2022

21. Validity of a screening tool for detecting subtle cognitive impairment in the middle-aged and elderly

Author

Bruce KM, Robinson SR, Smith JA, Yell, and GW

Subjects
Aging, Mild cognitive impairment, Neuropsychological test, Subtle Cognitive Impairment Test, Validation, Reliability, Geriatrics, RC952-954.6
Abstract

Kathryn M Bruce,1 Stephen R Robinson,2 Julian A Smith,1 Gregory W Yelland2,3 1Department of Surgery (MMC), Monash University, Clayton, 2School of Health Sciences, RMIT University, Bundoora, 3Central Clinical School, Monash University, Alfred Health, Melbourne, VIC, Australia Abstract: The present study tested 121 middle-aged and elderly community-dwelling individuals on the computer-based Subtle Cognitive Impairment Test (SCIT) and compared their performance with that on several neuropsychological tests. The SCIT had excellent internal consistency, as demonstrated by a high split-half reliability measure (0.88–0.93). Performance on the SCIT was unaffected by the confounding factors of sex, education level, and mood state. Many participants demonstrated impaired performance on one or more of the neuropsychological tests (Controlled Oral Word Association Task, Rey Auditory and Verbal Learning Task, Grooved Pegboard [GP], Complex Figures). Performance on SCIT subtests correlated significantly with performance on many of the neuropsychological subtests, and the best and worst performing quartiles on the SCIT subtest discriminated between good and poor performers on other subtests, collectively indicating concurrent validity of the SCIT. Principal components analysis indicated that SCIT performance does not cluster with performance on most of the other cognitive tests, and instead is associated with decision-making efficacy, and processing speed and efficiency. Thus, the SCIT is responsive to the processes that underpin multiple cognitive domains, rather than being specific for a single domain. Since the SCIT is quick and easy to administer, and is well tolerated by the elderly, it may have utility as a screening tool for detecting cognitive impairment in middle-aged and elderly populations. Keywords: aging, mild cognitive impairment, neuropsychological test, Subtle Cognitive Impairment Test, validation, reliability

Published
2014

22. Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke

Author

Jaworek, T, Xu, H, Gaynor, BJ, Cole, JW, Rannikmae, K, Stanne, TM, Tomppo, L, Abedi, V, Amouyel, P, Armstrong, ND, Attia, J, Bell, S, Benavente, OR, Boncoraglio, GB, Butterworth, A, Cervical Artery Dissections and Ischemic Stroke Patients (CADSIP) Consortium, Carcel-Marquez, J, Chen, Z, Chong, M, Cruchaga, C, Cushman, M, Danesh, J, Debette, S, Duggan, DJ, Durda, JP, Engstrom, G, Enzinger, C, Faul, JD, Fecteau, NS, Fernandez-Cadenas, I, Gieger, C, Giese, A-K, Grewal, RP, Grittner, U, Havulinna, AS, Heitsch, L, Hochberg, MC, Holliday, E, Hu, J, Ilinca, A, INVENT Consortium, Irvin, MR, Jackson, RD, Jacob, MA, Janssen, RR, Jimenez-Conde, J, Johnson, JA, Kamatani, Y, Kardia, SL, Koido, M, Kubo, M, Lange, L, Lee, J-M, Lemmens, R, Levi, CR, Li, J, Li, L, Lin, K, Lopez, H, Luke, S, Maguire, J, McArdle, PF, McDonough, CW, Meschia, JF, Metso, T, Muller-Nurasyid, M, O'Connor, TD, O'Donnell, M, Peddareddygari, LR, Pera, J, Perry, JA, Peters, A, Putaala, J, Ray, D, Rexrode, K, Ribases, M, Rosand, J, Rothwell, PM, Rundek, T, Ryan, KA, Sacco, RL, Salomaa, V, Sanchez-Mora, C, Schmidt, R, Sharma, P, Slowik, A, Smith, JA, Smith, NL, Wassertheil-Smoller, S, Soederholm, M, Stine, OC, Strbian, D, Sudlow, CL, Tatlisumak, T, Terao, C, Thijs, V, Torres-Aguila, NP, Tregouet, D-A, Tuladhar, AM, Veldink, JH, Walters, RG, Weir, DR, Woo, D, Worrall, BB, Hong, CC, Ross, O, Zand, R, Leeuw, F-ED, Lindgren, AG, Pare, G, Anderson, CD, Markus, HS, Jern, C, Malik, R, Dichgans, M, Mitchell, BD, Kittner, SJ, and Early Onset Stroke Genetics Consortium of the International Stroke Genetics Consortium (ISGC)

Subjects
Neurology & Neurosurgery, 1103 Clinical Sciences, 1109 Neurosciences, 1702 Cognitive Sciences
Abstract

BACKGROUND AND OBJECTIVES: Current genome-wide association studies of ischemic stroke have focused primarily on late onset disease. As a complement to these studies, we sought to identifythe contribution of common genetic variants to risk of early onset ischemic stroke. METHODS: We performed a meta-analysis of genome-wide association studies of early onset stroke (EOS), ages 18-59, using individual level data or summary statistics in 16,730 cases and 599,237 non-stroke controls obtained across 48 different studies. We further compared effect sizes at associated loci between EOS and late onset stroke (LOS) and compared polygenic risk scores for venous thromboembolism between EOS and LOS. RESULTS: We observed genome-wide significant associations of EOS with two variants in ABO, a known stroke locus. These variants tag blood subgroups O1 and A1, and the effect sizes of both variants were significantly larger in EOS compared to LOS. The odds ratio (OR) for rs529565, tagging O1, 0.88 (95% CI: 0.85-0.91) in EOS vs 0.96 (95% CI: 0.92-1.00) in LOS, and the OR for rs635634, tagging A1, was 1.16 (1.11-1.21) for EOS vs 1.05 (0.99-1.11) in LOS; p-values for interaction = 0.001 and 0.005, respectively. Using polygenic risk scores, we observed that greater genetic risk for venous thromboembolism, another prothrombotic condition, was more strongly associated with EOS compared to LOS (p=0.008). DISCUSSION: The ABO locus, genetically predicted blood group A, and higher genetic propensity for venous thrombosis are more strongly associated with EOS than with LOS, supporting a stronger role of prothrombotic factors in EOS.

Published
2022

23. SIXTEEN Shelter from the storm

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

24. FOURTEEN Centering racial justice in the US emergency response framework

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

25. FIFTEEN Affordable housing in America

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

26. PART V Housing insecurity

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

27. Afterword

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

28. SEVENTEEN Social problems in the age of culture wars

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

29. PART VI Looking forward

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

30. Cover

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

31. Title Page, Copyright

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

32. President's welcome

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

33. Table of Contents

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

34. ONE From blame to criminalization

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

35. PART I Crime, law, and policy

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

36. Editorial introduction

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

37. Notes on contributors

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

38. About the Society for the Study of Social Problems

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

39. SEVEN Inequality in the experiential core

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

40. TWO Curbing pretextual traffic stops to reduce racial profiling

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

41. FIVE News media and the crime coverage problem

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

42. FOUR Immigration enforcement

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

43. SIX Caught in the crossfire

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

44. THREE Pay to talk

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

45. PART II Education

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

46. TEN Reproductive health in crisis

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

47. PART IV Health and healthcare

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

48. PART III Food insecurity

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

49. TWELVE Gender-affirming healthcare for transgender and gender minority youth

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

50. EIGHT Addressing food insecurity through community-informed food retailer implementation

Author

Smith, Jason A., Nair, Manjusha, Muschert, Glenn W., Lane, David C., Dillaway, Heather, Budd, Kristen M., Bernstein, Mary, Johnson, Dana, Samara, Tony, Joseph, Tiffany, Sullivan, Teresa A., Ingel, Sydney, Webb, Sophie, Brubaker, Sarah Jane, Rose, Raquel, Ghandnoosh, Nazgol, Harrison, Monique, Van Natta, Meredith, Berezin, McKenzie, Redditt, Lindsay, Hannon, Lance, Burke, Kristen, Kerstetter, Katie, Kimpel, Jeanne, Carlisle, Hayley, Gonzalez, Gabriela, Windsor, Elroi, Bonner, Drew, Anderson, Charity, Cordes, Brooke, Silver, Blake R., Gwathney, Ashley N., and Rondini, Ashley C.

Published
2024

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