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Your search keyword '"Su, Ruijing"' showing total 31 results
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31 results on '"Su, Ruijing"'

8. UiO-66 nanoparticles combat influenza A virus in mice by activating the RIG-I-like receptor signaling pathway.

Author

Su, Ruijing, Li, Xinsen, Xiao, Jin, Xu, Jiawei, Tian, Jijing, Liu, Tianlong, and Hu, Yanxin

Subjects
*INFLUENZA A virus, *CELLULAR signal transduction, *INFLUENZA viruses, *NANOMEDICINE, *CYTOKINE release syndrome, *AMP-activated protein kinases, *TYPE I interferons
Abstract

The Influenza A virus (IAV) is a zoonotic pathogen that infects humans and various animal species. Infection with IAV can cause fever, anorexia, and dyspnea and is often accompanied by pneumonia characterized by an excessive release of cytokines (i.e., cytokine storm). Nanodrug delivery systems and nanoparticles are a novel approach to address IAV infections. Herein, UiO-66 nanoparticles (NPs) are synthesized using a high-temperature melting reaction. The in vitro and in vivo optimal concentrations of UiO-66 NPs for antiviral activity are 200 μg mL−1 and 60 mg kg−1, respectively. Transcriptome analysis revealed that UiO-66 NPs can activate the RIG-I-like receptor signaling pathway, thereby enhancing the downstream type I interferon antiviral effect. These NPs suppress inflammation-related pathways, including the FOXO, HIF, and AMPK signaling pathways. The inhibitory effect of UiO-66 NPs on the adsorption and entry of IAV into A549 cells is significant. This study presents novel findings that demonstrate the effective inhibition of IAV adsorption and entry into cells via UiO-66 NPs and highlights their ability to activate the cellular RIG-I-like receptor signaling pathway, thereby exerting an anti-IAV effect in vitro or in mice. These results provide valuable insights into the mechanism of action of UiO-66 NPs against IAV and substantial data for advancing innovative antiviral nanomedicine. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Microwave-assisted chlorination extraction of valuable metals from spent power ternary lithium-ion batteries

Author

Guan, Jie, Luo, Leilei, Su, Ruijing, Guo, Yaoguang, Zhang, Chenglong, Wang, Ruixue, Song, Xiaolong, Zhuang, Xuning, Zhang, Xihua, Zhang, Xiaojiao, Wu, Hongcheng, and Gu, Weixing

Subjects
Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, Soil Science, Environmental Chemistry, Pollution, Waste Management and Disposal, Water Science and Technology, Analytical Chemistry
Abstract

In the present study, a combined process of microwave-assisted chlorination roasting-water leaching was developed to efficiently extract metal ions from spent ternary lithium-ion batteries. Polyvinyl chloride (PVC) was used as chlorine source to generate HCl for chlorination reaction. Activated carbon was first selected as the optimal absorbing medium material. Subsequently, spent anode graphite was used to induce carbonisation reduction reaction with spent LiNixCoyMnzO2 (NCM) to promote recovery of valuable metals. The characterisations of X-Ray Diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscope (SEM) and thermodynamic analysis indicated that HCl derived from PVC pyrolysis could spontaneously react with carbonisation reduction products from spent NCM to form the corresponding water-soluble metal chloride for the effective recovery of valuable metals. Under the optimal conditions with reaction temperature at 450°C, material mass ratio PVC:NCM of 4:1, reaction time at 60 min and microwave power at 500 W, 96.43% of Li, 95.51% of Ni, 95.27% of Co and 95.43% of Mn can be recovered, respectively. The leaching kinetics can be described by the Avrami equation with surface chemical reaction controlled, and the leaching activation energies of Li, Ni, Co and Mn were 36.32, 42.31, 38.84 and 41.96 kJ∙mol−1, respectively. This microwave-assisted method might provide a new route for the effective recycling of spent lithium-ion batteries by chlorinated metallurgical processes.

Published
2022
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13. Behaviour and mechanism of indium extraction from waste liquid-crystal display panels by microwave-assisted chlorination metallurgy

Author

Chen Shuai, Dai Jue, Gao Guilan, Gu Weixing, Guan Jie, Guo Yaoguang, Su Ruijing., Wu Hongchen, Yuan Hao, Chen Shuai, Dai Jue, Gao Guilan, Gu Weixing, Guan Jie, Guo Yaoguang, Su Ruijing., Wu Hongchen, and Yuan Hao

Abstract

Using ammonium chloride as a chlorination agent, indium in waste liquid-crystal display panels was successfully extracted by microwave-assisted chloride metallurgy under vacuum pressure. The optimal conditions for indium extraction from pure indium oxide were explored through single-factor and orthogonal experiments, achieving an indium extraction ratio of 98.91% when the temperature was 500 degrees C, the Cl/In molar ratio was 8, and the heating duration was 3 min for pure In2O3. The Cl/In molar ratio exhibited the most important effect on the indium extraction ratio, followed by the heating temperature and duration. When extracting indium from waste liquid-crystal display panel powder (–13 micron) after ball milling, the indium extraction ratio was nearly 79.46% when using an ammonium chloride mass ratio of 0.6 wt.%, temperature of 500 degrees C, and heating duration of 3 min. Excess gaseous hydrogen chloride reacts with ammonia to form ammonium chloride during the condensation, thereby avoiding emission of hydrogen chloride into the environment. The results of this work indicate that this technology represents a promising option for the extraction of indium from waste liquid-crystal display panels with a very short heating duration and relatively low chlorination agent loss, as well as no harmful gas emissions. (Authors.), Using ammonium chloride as a chlorination agent, indium in waste liquid-crystal display panels was successfully extracted by microwave-assisted chloride metallurgy under vacuum pressure. The optimal conditions for indium extraction from pure indium oxide were explored through single-factor and orthogonal experiments, achieving an indium extraction ratio of 98.91% when the temperature was 500 degrees C, the Cl/In molar ratio was 8, and the heating duration was 3 min for pure In2O3. The Cl/In molar ratio exhibited the most important effect on the indium extraction ratio, followed by the heating temperature and duration. When extracting indium from waste liquid-crystal display panel powder (–13 micron) after ball milling, the indium extraction ratio was nearly 79.46% when using an ammonium chloride mass ratio of 0.6 wt.%, temperature of 500 degrees C, and heating duration of 3 min. Excess gaseous hydrogen chloride reacts with ammonia to form ammonium chloride during the condensation, thereby avoiding emission of hydrogen chloride into the environment. The results of this work indicate that this technology represents a promising option for the extraction of indium from waste liquid-crystal display panels with a very short heating duration and relatively low chlorination agent loss, as well as no harmful gas emissions. (Authors.)

Published
2021

30. Indium recovery from waste liquid crystal displays by polyvinyl chloride waste

Author

Guan, Jie, primary, Wang, Shuai, additional, Ren, Haohua, additional, Guo, Yaoguang, additional, Yuan, Hao, additional, Yan, Xingru, additional, Guo, Jiang, additional, Gu, Weixing, additional, Su, Ruijing, additional, Liang, Bo, additional, Gao, Guilan, additional, Zhou, Yuan, additional, Xu, Jinqiu, additional, and Guo, Zhanhu, additional

Published
2015
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