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Your search keyword '"Thiruneelakandan, G."' showing total 4 results
Start Over Author "Thiruneelakandan, G." Publication Year Range Last 10 years
4 results on '"Thiruneelakandan, G."'

2. EXPERIMENTAL ANALYSIS AND THERMAL COMFORT INDEX OF AIR CONDITIONED MEETING HALL

Author

Jayabal S, Thiruneelakandan G, and Daniel Lawrence I

Subjects
Engineering, Index (economics), Indoor air quality, Meteorology, business.industry, Living environment, Direct reading, Airflow, Building energy, Thermal comfort, Relative humidity, business
Abstract

India’s building energy consumption is increasing continuously. The subcontinent does not have custom made thermal comfort standards. We conducted thermal comfort field study in meeting hall, Madurai, tamilnadu, india. Experimental study of thermal comfort was conducted in three levels of load conditions and three levels of air flow in meeting hall during summer 2014. The above three level of load condition and air flow measurements values observed by using direct reading instruments. Thermal comfort indices were also calculated and compare to the natural ventilated meeting hall and outdoor environment. This study aims to evaluate the indoor comfort quality of the meeting hall. This paper is focused on improving the indoor air quality by controlling the vital parameters like carbon dioxide, carbon monoxide, oxygen, room temperature, relative velocity and relative humidity which were used as indicators for indoor air quality and comfort levels. The investigated meeting hall building is located in India, tamilnadu, Madurai and the volume of the building is about 10.60m (length) × 9.14m (width) × 3m (height). This paper provides the detailed specifications to improve the thermal comfort in the air conditioned living atmosphere and ensure safety and healthy living environment. This paper contained Experimental analysis and Calculation of thermal comfort index.

Published
2014

4. Exploring marine Lactobacillus and its protein for probiotic-based oral cancer therapy.

Author

Vidya S, Thiruneelakandan G, Krishnamoorthy R, Subbarayan S, Maran BAV, Alshuniaber MA, Gatasheh MK, Sunday BY, and Ahmad A

Subjects
Male, Humans, Lactobacillus metabolism, India, Molecular Docking Simulation, Cyclic AMP-Dependent Protein Kinases metabolism, Mouth Neoplasms, Probiotics therapeutic use, Probiotics pharmacology
Abstract

Cancer is a life-threatening malignancy and one of the leading global causes of human mortality. New approaches are required for cancer therapy due to the unique properties of cancer cells and the side effects of chemotherapy. Probiotics have gained significant attention in the prevention and treatment of various diseases, including cancer. Therefore, the current study aimed to investigate the anti-cancer effects of probiotics, such as marine Lactobacillus species and their proteins. Five marine Lactobacillus species were isolated and identified from the Tamil Nadu Mangrove Pichavaram (TLMP) forest and named TLMP1, TLMP2, TLMP3, TLMP4, and TLMP5. The Lactobacillus isolates, and their proteins were administered to male golden Syrian hamsters. Tumor formation was effectively controlled in hamsters treated with crude Lactobacillus, extending their lifespan. Additionally, Lactobacillus proteins demonstrated an inhibitory effect on tumor formation in the treated group compared to the control. Molecular docking analysis revealed that Lactobacillus proteins interacted significantly with the cAMP-dependent protein kinase catalytic subunit alpha. Amino acid residues LYS791, MET793, ARG841, ARG842, and LEU844 were involved in active site binding and played a crucial role in inhibiting cAMP-dependent protein kinase., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023. Published by Elsevier B.V.)

Published
2024
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