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Your search keyword '"Wang, Bai-Yan"' showing total 18 results
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18 results on '"Wang, Bai-Yan"'

2. Four-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2)

Author

Zhao, Wan-Hong, Wang, Bai-Yan, Chen, Li-Juan, Fu, Wei-Jun, Xu, Jie, Liu, Jie, Jin, Shi-Wei, Chen, Yin-Xia, Cao, Xing-Mei, Yang, Yun, Zhang, Yi-Lin, Wang, Fang-Xia, Zhang, Peng-Yu, Lei, Bo, Gu, Liu-Fang, Wang, Jian-Li, Zhang, Hui, Bai, Ju, Xu, Yan, Zhu, Han, Du, Juan, Jiang, Hua, Fan, Xiao-Hu, Li, Jian-Yong, Hou, Jian, Chen, Zhu, Zhang, Wang-Gang, Mi, Jian-Qing, Chen, Sai-Juan, and He, Ai-Li

Published
2022
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3. Five-year remission without disease progression in a patient with relapsed/refractory multiple myeloma with extramedullary disease treated with LCAR-B38M chimeric antigen receptor T cells in the LEGEND-2 study: a case report

Author

Wang, Bai-Yan, Zhao, Wan-Hong, Chen, Yin-Xia, Cao, Xing-Mei, Yang, Yun, Zhang, Yi-Lin, Wang, Fang-Xia, Zhang, Peng-Yu, Lei, Bo, Gu, Liu-Fang, Wang, Jian-Li, Bai, Ju, Xu, Yan, Wang, Xu-Geng, Zhang, Rui-Li, Wei, Li-Li, Zhuang, Qiu-Chuan, Fan, Frank, Zhang, Wang-Gang, He, Ai-Li, and Liu, Jie

Published
2022
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4. Long-term remission and survival in patients with relapsed or refractory multiple myeloma after treatment with LCAR-B38M CAR T cells: 5-year follow-up of the LEGEND-2 trial

Author

Xu, Jie, primary, Wang, Bai-Yan, additional, Yu, Shan-He, additional, Chen, Shi-Jun, additional, Yang, Shuang-Shuang, additional, Liu, Rui, additional, Chen, Li-Juan, additional, Hou, Jian, additional, Chen, Zhu, additional, Zhao, Wan-Hong, additional, He, Ai-Li, additional, Mi, Jian-Qing, additional, and Chen, Sai-Juan, additional

Published
2024
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5. P874: LONG-TERM REMISSION AND SURVIVAL IN PATIENTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA AFTER TREATMENT OF LCAR-B38M CAR-T – AT LEAST 5-YEAR FOLLOW-UP IN LEGEND-2

Author

MI, Jian‑qing, primary, Zhao, Wan‑hong, additional, Chen, Li‑juan, additional, Fu, Weijun, additional, Wang, Bai‑yan, additional, Xu, Jie, additional, Liu, Jie, additional, Jin, Shi‑wei, additional, Zhu, Han, additional, Du, Juan, additional, Jiang, Hua, additional, Sun, Huabin, additional, Jia, Yehui, additional, Fan, Xiao‑hu, additional, LI, Jian‑yong, additional, Hou, Jian, additional, Chen, Zhu, additional, Zhang, Wang‑gang, additional, He, Ai‑li, additional, and Chen, Sai‑juan, additional

Published
2023
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6. Serum containing drugs of Gua Lou Xie Bai decoction (GLXB-D) can inhibit TGF-β1-Induced Epithelial to Mesenchymal Transition (EMT) in A549 Cells

Author

Li Rui-qin, Wang Bai-yan, Ding Yu-wen, Zhang Rui, Zhang Jun-xia, and Lu Xiao-kang

Subjects
pulmonary fibrosis, tgf-β1, emt, glxb-d, Chemistry, QD1-999
Abstract

The present study explores the mechanism of resistance to pulmonary fibrosis by observing the possible effects of serum containing drugs prepared from Gua Lou Xie Bai decoction (GLXB-D) on transforming growth factor beta 1 (TGF-β1) induced Epithelial-mesenchymal transition (EMT) of A549 human alveolar epithelial cells. The inhibition rate was observed with the help of thiazolyl blue tetrazolium bromide (MTT) in 24 h and 48 h treated cells. Inverted microscope and transmission electron microscope (TEM) were used to study the changes in the morphology and ultrastructure of the cells. The expressions of E-cadherin and Vimentin were comparatively analyzed by Western blotting, while the expressions of Collagen I and III were analyzed by ELISA. The data obtained indicated that the expression of epithelial marker E-cadherin was decreased, while the expressions of EMT markers such as Vimentin and Collagen I and III were increased in 24 h after TGF-β1 induction. However, the serum containing drugs of GLXB-D were found to inhibit the TGF-β1 induced proliferation of cells, increase the expression of E-cadherin and decrease the expression of Vimentin, collagen I and III. In conclusion, the serum containing drugs of GLXB-D effectively reduced pulmonary fibrosis, mainly via the reversal of EMT induction by TGF-β1. Thus, it can be considered as a potential candidate for the development of better treatment methods for pulmonary fibrosis.

Published
2018
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7. A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma

Author

Zhao, Wan-Hong, Liu, Jie, Wang, Bai-Yan, Chen, Yin-Xia, Cao, Xing-Mei, Yang, Yun, Zhang, Yi-Lin, Wang, Fang-Xia, Zhang, Peng-Yu, Lei, Bo, Gu, Liu-Fang, Wang, Jian-Li, Yang, Nan, Zhang, Ru, Zhang, Hui, Shen, Ying, Bai, Ju, Xu, Yan, Wang, Xu-Geng, Zhang, Rui-Li, Wei, Li-Li, Li, Zong-Fang, Li, Zhen-Zhen, Geng, Yan, He, Qian, Zhuang, Qiu-Chuan, Fan, Xiao-Hu, He, Ai-Li, and Zhang, Wang-Gang

Published
2018
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8. Additional file 1 of Four-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2)

Author

Zhao, Wan-Hong, Wang, Bai-Yan, Chen, Li-Juan, Fu, Wei-Jun, Xu, Jie, Liu, Jie, Jin, Shi-Wei, Chen, Yin-Xia, Cao, Xing-Mei, Yang, Yun, Zhang, Yi-Lin, Wang, Fang-Xia, Zhang, Peng-Yu, Lei, Bo, Gu, Liu-Fang, Wang, Jian-Li, Zhang, Hui, Bai, Ju, Xu, Yan, Zhu, Han, Du, Juan, Jiang, Hua, Fan, Xiao-Hu, Li, Jian-Yong, Hou, Jian, Chen, Zhu, Zhang, Wang-Gang, Mi, Jian-Qing, Chen, Sai-Juan, and He, Ai-Li

Abstract

Additional file1: Fig. S1. Study Design. Fig. S2. A Duration of response, B overall survival, and C progression-free survival by cytogenetic risk. Fig. S3. Relationship of duration of response with A sBCMA, B transgene persistence, and C antidrug antibodies. Table S1. Best response by subgroup. Table S2. Best response by prior therapy. Table S3. sBCMA levels. Table S4. sBCMA levels by response. Table S5. Transgene persistence by lymphodepletion regimen, PD, and ADA. Table S6. Immunoglobulin recovery over time.

Published
2022
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9. Design and implementation of remote image processing system for space launch site

Author

Wang Bai Yan, WangYu Chao, Ma Li, Li Peng, Liu Tao, and Xiang Yu

Subjects
lcsh:GE1-350, Data processing, business.product_category, Computer science, Real-time computing, 0211 other engineering and technologies, Process (computing), ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Image processing, ComputerApplications_COMPUTERSINOTHERSYSTEMS, 02 engineering and technology, 010501 environmental sciences, 01 natural sciences, Space launch, Transmission (telecommunications), Rocket, 021108 energy, Information flow (information theory), business, Decoding methods, lcsh:Environmental sciences, 0105 earth and related environmental sciences
Abstract

Telemetry image has the characteristics of intuitive image in the process of rocket flight. Through real-time acquisition of rocket flight video image, it can provide the working status of key nodes in the process of rocket flight, and provide intuitive decision-marking auxiliary information for commanders. This paper analyzes the design content of the image processing system of the space launch site from the aspects of image transmission mechanism, information flow, image data processing and image decoding, so as to provide technical basis for the image receiving, transmission and decoding process in the engineering practice of the image processing system.

Published
2021

10. Can we enhance osteoporotic metaphyseal fracture healing through enhancing ultrastructural and functional changes of osteocytes in cortical bone with low‐magnitude high‐frequency vibration?

Author

Choy, Man‐Huen Victoria, primary, Wong, Ronald Man‐Yeung, additional, Li, Meng‐Chen, additional, Wang, Bai Yan, additional, Liu, Xiao Dong, additional, Lee, Wayne, additional, Cheng, Jack Chun‐Yiu, additional, Chow, Simon Kwoon‐Ho, additional, and Cheung, Wing‐Hoi, additional

Published
2020
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12. Long-Term Follow-up of a Phase 1, First-in-Human Open-Label Study of LCAR-B38M, a Structurally Differentiated Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting B-Cell Maturation Antigen (BCMA), in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM)

Author

Wang, Bai-Yan, primary, Zhao, Wan-Hong, primary, Liu, Jie, primary, Chen, Yin-Xia, primary, Cao, Xing-Mei, primary, Yang, Yun, primary, Zhang, Yi-Lin, primary, Wang, Fang-Xia, primary, Zhang, Peng-Yu, primary, Lei, Bo, primary, Gu, Liu-Fang, primary, Wang, Jian-Li, primary, Zhang, Jia-Jia, primary, Zhang, Ru, primary, Zhang, Hui, primary, Shen, Ying, primary, Bai, Ju, primary, Xu, Yan, primary, Wang, Xu-Geng, primary, Zhang, Rui-Li, primary, Wei, Li-Li, primary, Li, Zong-Fang, primary, He, Gai-Xia, primary, Geng, Yan, primary, He, Qian, primary, Zhuang, Qiu-Chuan, primary, Fan, Frank Xiao-Hu, primary, Zhang, Wang-Gang, primary, and He, Ai-Li, primary

Published
2019
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13. Updated Analysis of a Phase 1, Open-Label Study of LCAR-B38M, a Chimeric Antigen Receptor T Cell Therapy Directed Against B-Cell Maturation Antigen, in Patients with Relapsed/Refractory Multiple Myeloma

Author

Zhao, Wan-Hong, primary, Liu, Jie, additional, Wang, Bai-Yan, additional, Chen, Yin-Xia, additional, Cao, Xing-Mei, additional, Yang, Yun, additional, Zhang, Yi-Lin, additional, Wang, Fang-Xia, additional, Zhang, Peng-Yu, additional, Lei, Bo, additional, Gu, Liu-Fang, additional, Wang, Jian-Li, additional, Yang, Nan, additional, Zhang, Ru, additional, Zhang, Hui, additional, Shen, Ying, additional, Bai, Ju, additional, Xu, Yan, additional, Wang, Xu-Geng, additional, Zhang, Rui-Li, additional, Wei, Li-Li, additional, Li, Zong-Fang, additional, Li, Zhen-Zhen, additional, Geng, Yan, additional, He, Qian, additional, Zhuang, Qiu-Chuan, additional, Fan, Frank Xiao-Hu, additional, He, Ai-Li, additional, and Zhang, Wang-Gang, additional

Published
2018
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15. Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia

Author

Liu, Yuan-Fang, primary, Wang, Bai-Yan, additional, Zhang, Wei-Na, additional, Huang, Jin-Yan, additional, Li, Ben-Shang, additional, Zhang, Ming, additional, Jiang, Lu, additional, Li, Jian-Feng, additional, Wang, Ming-Jie, additional, Dai, Yu-Jun, additional, Zhang, Zi-Guan, additional, Wang, Qiang, additional, Kong, Jie, additional, Chen, Bing, additional, Zhu, Yong-Mei, additional, Weng, Xiang-Qin, additional, Shen, Zhi-Xiang, additional, Li, Jun-Min, additional, Wang, Jin, additional, Yan, Xiao-Jing, additional, Li, Yan, additional, Liang, Ying-Min, additional, Liu, Li, additional, Chen, Xie-Qun, additional, Zhang, Wang-Gang, additional, Yan, Jin-Song, additional, Hu, Jian-Da, additional, Shen, Shu-Hong, additional, Chen, Jing, additional, Gu, Long-Jun, additional, Pei, Deqing, additional, Li, Yongjin, additional, Wu, Gang, additional, Zhou, Xin, additional, Ren, Rui-Bao, additional, Cheng, Cheng, additional, Yang, Jun J., additional, Wang, Kan-Kan, additional, Wang, Sheng-Yue, additional, Zhang, Jinghui, additional, Mi, Jian-Qing, additional, Pui, Ching-Hon, additional, Tang, Jing-Yan, additional, Chen, Zhu, additional, and Chen, Sai-Juan, additional

Published
2016
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18. Genome-Wide Abnormality Patterns of B-Lineage Acute Lymphoblastic Leukemia in Adults in Comparison with Pediatric Cases

Author

Wang, Bai-Yan, primary, Liu, Yuan-Fang, additional, Tang, Jing-Yan, additional, Gu, Zhao-Hui, additional, Zhang, Wei-Na, additional, Zhang, Zi-Guan, additional, Wang, Qiang, additional, Chen, Bing, additional, Wang, Sheng-Yue, additional, Zhu, Yong-Mei, additional, Li, Jun-Min, additional, Wang, Jin, additional, Bai, Yun, additional, Lu, Gang, additional, Yang, Min-Jun, additional, Zhang, Jin-Li, additional, Shi, Jing-Yi, additional, Wang, Kan-Kan, additional, Pan, Chun-Ming, additional, Lu, Jing, additional, Jiang, Lu, additional, Li, Yang, additional, Zhao, Chun-Jun, additional, Chen, Jing, additional, Gu, Long-Jun, additional, Mi, Jian-Qing, additional, Li, Ben-Shang, additional, Chen, Zhu, additional, and Chen, Sai-Juan, additional

Published
2014
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