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Cavitation in tubes is a common occurrence in nature and engineering applications. Previous studies of cavitation bubble dynamics mainly consider bubbles in stagnant-water tubes, but the dynamics of cavitation bubbles in tubes with flow is not clear. This study investigates the dynamics of cavitation bubbles in tubes with flow by numerical simulations. The results show that, unlike bubbles in stagnant-water tubes, bubbles under the combined effects of water inflow and tube wall confinement exhibit asymmetric behavior along the axis of the tube. The inflow suppresses the development of the bubble interface near the tube inlet, causing that side of the interface to move with the inflow. In contrast, the expansion and contraction of the bubble and the generation of liquid jets occur on the side near the outlet. This feature results in significant asymmetry in the bubble interface, therefore we introduce a skewness parameter to characterize the difference in length between the left and right parts of the bubble during the bubble evolution. The evolution of the bubble significantly affects the mass flow rate at the outlet of the tube, and even leads to backflow during the bubble contraction process., Comment: 18 pages, 15 figures

Recommender Systems (RSs) provide personalized recommendation service based on user interest, which are widely used in various platforms. However, there are lots of users with sparse interest due to lacking consumption behaviors, which leads to poor recommendation results for them. This problem is widespread in large-scale RSs and is particularly difficult to address. To solve this problem, we propose a novel solution named User Interest Enhancement (UIE) which enhances user interest including user profile and user history behavior sequences using the enhancement vectors and personalized enhancement vector generated based on stream clustering and memory networks from different perspectives. UIE not only remarkably improves model performance on the users with sparse interest but also significantly enhance model performance on other users. UIE is an end-to-end solution which is easy to be implemented based on ranking model. Moreover, we expand our solution and apply similar methods to long-tail items, which also achieves excellent improvement. Furthermore, we conduct extensive offline and online experiments in a large-scale industrial RS. The results demonstrate that our model outperforms other models remarkably, especially for the users with sparse interest. Until now, UIE has been fully deployed in multiple large-scale RSs and achieved remarkable improvements.

Cavitation is a common phenomenon in nature and has numerous applications. In contrast to a cavitation bubble in a free domain, a cavitation bubble in a thin tube is restricted by the tube wall, which is expected to significantly affect bubble evolution but its mechanism is still unclear. In this study, the dynamics of a cavitation bubble in a thin circular tube is studied by numerical simulation, focusing on the confinement effects of the tube. The results show that besides affecting the size and lifetime of the bubble, the confinement effects of the tube lead to the generation of counter jets and a ring jet during the contraction process of the bubble, and the curvature of the two counter jets determines the ring jet's peak velocity. When the bubble deviates from the midpoint of the tube in the axial direction, the two sides of the bubble along the axial direction show asymmetric behaviors, which results in the bubble migrating toward the midpoint. The tube diameter, tube length, liquid viscosity, and initial bubble position, can significantly influence the degree of confinement effects, which can be characterized by the variations of several key indicators, such as bubble size, lifetime, degree of deformation, counter jet velocity, ring jet velocity, and axial migration of the bubble., Comment: 15 pages, 13 figures

This study introduces the 3D Residual-in-Residual Dense Block GAN (3D RRDB-GAN) for 3D super-resolution for radiology imagery. A key aspect of 3D RRDB-GAN is the integration of a 2.5D perceptual loss function, which contributes to improved volumetric image quality and realism. The effectiveness of our model was evaluated through 4x super-resolution experiments across diverse datasets, including Mice Brain MRH, OASIS, HCP1200, and MSD-Task-6. These evaluations, encompassing both quantitative metrics like LPIPS and FID and qualitative assessments through sample visualizations, demonstrate the models effectiveness in detailed image analysis. The 3D RRDB-GAN offers a significant contribution to medical imaging, particularly by enriching the depth, clarity, and volumetric detail of medical images. Its application shows promise in enhancing the interpretation and analysis of complex medical imagery from a comprehensive 3D perspective.

The value of preclinical diffusion MRI (dMRI) is substantial. While dMRI enables in vivo non-invasive characterization of tissue, ex vivo dMRI is increasingly being used to probe tissue microstructure and brain connectivity. Ex vivo dMRI has several experimental advantages including higher signal-to-noise ratio and spatial resolution compared to in vivo studies, and more advanced diffusion contrasts for improved microstructure and connectivity characterization. Another major advantage is direct comparison with histological data as a crucial methodological validation. However, there are a number of considerations that must be made when performing ex vivo experiments. The steps from tissue preparation, image acquisition and processing, and interpretation of results are complex, with many decisions that not only differ dramatically from in vivo imaging, but ultimately affect what questions can be answered using the data. This work represents 'Part 2' of a series of recommendations and considerations for preclinical dMRI, where we focus on best practices for dMRI of ex vivo tissue. We first describe the value that ex vivo imaging adds to the field of dMRI, followed by general considerations and foundational knowledge that must be considered when designing experiments. We then give guidelines for ex vivo protocols, including tissue preparation, imaging sequences and data processing including pre-processing, model-fitting, and tractography. Finally, we provide an online resource which lists publicly available ex vivo dMRI datasets and dedicated software packages. In each section, we attempt to provide guidelines and recommendations, but also highlight areas for which no guidelines exist, and where future work should lie. An overarching goal herein is to enhance the rigor and reproducibility of ex vivo dMRI acquisitions and analyses, and thereby advance biomedical knowledge., Comment: 59 pages, 12 figures, part of ongoing efforts on ISMRM Diffusion Study Group initiative 'Best Practices (Consensus) for diffusion MRI'. arXiv admin note: text overlap with arXiv:2209.12994

The value of in vivo preclinical diffusion MRI (dMRI) is substantial. Small-animal dMRI has been used for methodological development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. Many of the influential works in this field were first performed in small animals or ex vivo samples. The steps from animal setup and monitoring, to acquisition, analysis, and interpretation are complex, with many decisions that may ultimately affect what questions can be answered using the resultant data. This work aims to present selected recommendations and guidelines from the diffusion community, on best practices for preclinical dMRI of in vivo animals. We describe the general considerations and foundational knowledge that must be considered when designing experiments. We briefly describe differences in animal species and disease models and discuss why some may be more or less appropriate for different studies. We then give guidelines for in vivo acquisition protocols, including decisions on hardware, animal preparation, and imaging sequences, followed by advice for data processing including pre-processing, model-fitting, and tractography. Finally, we provide an online resource which lists publicly available preclinical dMRI datasets and software packages, to promote responsible and reproducible research. In each section, we attempt to provide guides and recommendations, but also highlight areas for which no guidelines exist (and why), and where future work should focus. An overarching goal herein is to enhance the rigor and reproducibility of small animal dMRI acquisitions and analyses, and thereby advance biomedical knowledge., Comment: 45 pages, 5 figures, 1 table

Embedding & MLP has become a paradigm for modern large-scale recommendation system. However, this paradigm suffers from the cold-start problem which will seriously compromise the ecological health of recommendation systems. This paper attempts to tackle the item cold-start problem by generating enhanced warmed-up ID embeddings for cold items with historical data and limited interaction records. From the aspect of industrial practice, we mainly focus on the following three points of item cold-start: 1) How to conduct cold-start without additional data requirements and make strategy easy to be deployed in online recommendation scenarios. 2) How to leverage both historical records and constantly emerging interaction data of new items. 3) How to model the relationship between item ID and side information stably from interaction data. To address these problems, we propose a model-agnostic Conditional Variational Autoencoder based Recommendation(CVAR) framework with some advantages including compatibility on various backbones, no extra requirements for data, utilization of both historical data and recent emerging interactions. CVAR uses latent variables to learn a distribution over item side information and generates desirable item ID embeddings using a conditional decoder. The proposed method is evaluated by extensive offline experiments on public datasets and online A/B tests on Tencent News recommendation platform, which further illustrate the advantages and robustness of CVAR., Comment: 6 pages, 2 figures, accepted as SIGIR 2022 short paper

Diffusion Magnetic Resonance Imaging (dMRI) is a promising method to analyze the subtle changes in the tissue structure. However, the lengthy acquisition time is a major limitation in the clinical application of dMRI. Different image acquisition techniques such as parallel imaging, compressed sensing, has shortened the prolonged acquisition time but creating high-resolution 3D dMRI slices still requires a significant amount of time. In this study, we have shown that high-resolution 3D dMRI can be reconstructed from the highly undersampled k-space and q-space data using a Kernel LowRank method. Our proposed method has outperformed the conventional CS methods in terms of both image quality and diffusion maps constructed from the diffusion-weighted images, Comment: This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible

A connectome is a map of the structural and/or functional connections in the brain. This information-rich representation has the potential to transform our understanding of the relationship between patterns in brain connectivity and neurological processes, disorders, and diseases. However, existing computational techniques used to analyze connectomes are oftentimes insufficient for interrogating multi-subject connectomics datasets: most current methods are either solely designed to analyze single connectomes, or leverage heuristic graph statistics that are unable to capture the complete topology of connections between brain regions. To enable more rigorous connectomics analysis, we introduce a set of robust and interpretable statistical hypothesis tests motivated by recent theoretical advances in random graph models. These tests facilitate simultaneous analysis of multiple connectomes across different levels of network topology, enabling the robust and reproducible discovery of hierarchical brain structures that vary in relation with phenotypic profiles. In addition to explaining the theoretical foundations and guarantees of our hypothesis tests, we demonstrate their superiority over current state-of-the-art connectomics methods through extensive simulation studies, as well as synthetic and real-data experiments. Using a set of high-resolution connectomes obtained from genetically distinct mouse strains (including the BTBR mouse -- a standard model of autism -- and three behavioral wild-types), we illustrate how our methods can be used to successfully uncover latent information in multi-subject connectomics data and yield valuable insights into the connective correlates of neurological phenotypes. The code necessary to reproduce the analyses, simulations, and figures presented in this work are available in a series of Jupyter Notebooks (https://github.com/neurodata/MCC)., Comment: 29 pages, 12 figures