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36 results on '"West, Sheila G."'

1. Common Variants in Lipid Metabolism–Related Genes Associate with Fat Mass Changes in Response to Dietary Monounsaturated Fatty Acids in Adults with Abdominal Obesity

Author

Hammad, Shatha S, Eck, Peter, Sihag, Jyoti, Chen, Xiang, Connelly, Philip W, Lamarche, Benoît, Couture, Patrick, Guay, Valérie, Maltais-Giguère, Julie, West, Sheila G, Kris-Etherton, Penny M, Bowen, Kate J, Jenkins, David J A, Taylor, Carla G, Perera, Danielle, Wilson, Angela, Castillo, Sandra, Zahradka, Peter, and Jones, Peter J H

Published
2019
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2. Assessing the impact of the diet on cardiometabolic outcomes: are multiple measurements post-intervention necessary?

Author

Allaire, Janie, Talbot, Denis, Couture, Patrick, Tchernof, André, Jones, Peter J. H., Kris-Etherton, Penny, and West, Sheila G.

Subjects
Unilever Canada Ltd., Bunge Ltd., Medical research -- Measurement, Medicine, Experimental -- Measurement, Agricultural processing industry -- Measurement, C-reactive protein -- Measurement, Diet -- Measurement, Food/cooking/nutrition, Health
Abstract

The purpose of this study was to examine how using the mean of two consecutive measurements vs. one measurement post-treatment influences the sample size required to detect changes in cardiometabolic risk factors in dietary studies. For a given statistical power, using the mean of two measurements taken on consecutive days post-treatment instead of a single measurement significantly reduces the sample size required to observe changes in triglyceride, total apolipoprotein B100, and C-reactive protein concentrations in the context of a supplementation study. In the context of a controlled-feeding study, this gain is seen only in the case of change in triglyceride concentrations., Author(s): Janie Allaire [sup.1], Denis Talbot [sup.2] [sup.3], Patrick Couture [sup.1] [sup.2], André Tchernof [sup.2] [sup.4], Peter J. H. Jones [sup.5], Penny Kris-Etherton [sup.6], Sheila G. West [sup.6], Philip W. [...]

Published
2019
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7. Effects of Diets Enriched with Conventional or High-Oleic Canola Oils on Vascular Endothelial Function: A Sub-Study of the Canola Oil Multi-Centre Intervention Trial 2 (COMIT-2), a Randomized Crossover Controlled Feeding Study

Author

Davis, Kristin M., primary, Petersen, Kristina S., additional, Bowen, Kate J., additional, Jones, Peter J. H., additional, Taylor, Carla G., additional, Zahradka, Peter, additional, Letourneau, Karen, additional, Perera, Danielle, additional, Wilson, Angela, additional, Wagner, Paul R., additional, Kris-Etherton, Penny M., additional, and West, Sheila G., additional

Published
2022
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9. L-arginine supplementation alleviates post-prandial endothelial dysfunction when baseline fasting plasma arginine concentration is low: a randomized controlled trial in healthy subjects with risk factors for metabolic syndrome: PO.048

Author

Deveaux, Ambre, Pham, Isabelle, West, Sheila G, André, Etienne, Lantoine-Adam, Frédérique, Bunouf, Pierre, Sadi, Samira, Hermier, Dominique, Mathé, Véronique, Fouillet, Helene, Huneau, Jean-Francois, Benamouzig, Robert, and Mariotti, François

Published
2016

10. Polymorphisms in the stearoyl-CoA desaturase gene modify blood glucose response to dietary oils varying in MUFA content in adults with obesity

Author

Mutch, David M., primary, Lowry, Dana E., additional, Roth, Michael, additional, Sihag, Jyoti, additional, Hammad, Shatha S., additional, Taylor, Carla G., additional, Zahradka, Peter, additional, Connelly, Philip W., additional, West, Sheila G., additional, Bowen, Kate, additional, Kris-Etherton, Penny M., additional, Lamarche, Benoît, additional, Couture, Patrick, additional, Guay, Valérie, additional, Jenkins, David J. A., additional, Eck, Peter, additional, and Jones, Peter J. H., additional

Published
2021
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11. Polymorphisms in the stearoyl-CoA desaturase gene modify blood glucose response to dietary oils varying in MUFA content in adults with obesity.

Author

Mutch, David M., Lowry, Dana E., Roth, Michael, Sihag, Jyoti, Hammad, Shatha S., Taylor, Carla G., Zahradka, Peter, Connelly, Philip W., West, Sheila G., Bowen, Kate, Kris-Etherton, Penny M., Lamarche, Benoît, Couture, Patrick, Guay, Valérie, Jenkins, David J. A., Eck, Peter, and Jones, Peter J. H.

Subjects
FATS & oils, UNSATURATED fatty acids, OBESITY, RESEARCH, FASTING, FAT content of food, SATURATED fatty acids, GLYCEMIC control, GENETIC polymorphisms, BLOOD sugar, DIET, MEDICAL cooperation, TREATMENT effectiveness, RANDOMIZED controlled trials, NUTRITIONAL genomics, DESCRIPTIVE statistics, GENOTYPES, OXIDOREDUCTASES, CROSSOVER trials, CANOLA oil
Abstract

The article focuses on polymorphisms in the stearoyl-CoA desaturase gene modify blood glucose response to dietary oils varying in MUFA content in adults with obesity.

Published
2022
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13. Diets Enriched with Conventional or High-Oleic Acid Canola Oils Lower Atherogenic Lipids and Lipoproteins Compared to a Diet with a Western Fatty Acid Profile in Adults with Central Adiposity

Author

Bowen, Kate J, primary, Kris-Etherton, Penny M, additional, West, Sheila G, additional, Fleming, Jennifer A, additional, Connelly, Philip W, additional, Lamarche, Benoît, additional, Couture, Patrick, additional, Jenkins, David JA, additional, Taylor, Carla G, additional, Zahradka, Peter, additional, Hammad, Shatha S, additional, Sihag, Jyoti, additional, Chen, Xiang, additional, Guay, Valérie, additional, Maltais-Giguère, Julie, additional, Perera, Danielle, additional, Wilson, Angela, additional, Juan, Sandra Castillo San, additional, Rempel, Julia, additional, and Jones, Peter JH, additional

Published
2019
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14. Effects of Canola and High-Oleic Acid Canola Oils on Abdominal Fat Mass in Individuals with Central Obesity

Author

Liu, Xiaoran, Kris-Etherton, Penny M., West, Sheila G., Lamarche, Benoît, Jenkins, David J. A., Fleming, Jennifer A., McCrea, Cindy E., Pu, Shuaihua, Couture, Patrick, Connelly, Philip W., and Jones, Peter J. H.

Subjects
Adult, Male, Linseed Oil, Docosahexaenoic Acids, Abdominal Fat, Blood Pressure, Article, Body Mass Index, Young Adult, Absorptiometry, Photon, Risk Factors, Humans, Plant Oils, Safflower Oil, Triglycerides, Aged, Metabolic Syndrome, Cross-Over Studies, Body Weight, Cholesterol, HDL, Cholesterol, LDL, Middle Aged, Diet, Obesity, Abdominal, Body Composition, Female, Rapeseed Oil, Corn Oil, Oleic Acid
Abstract

To determine the effect of diets low in saturated fatty acids and high in monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids on body composition in participants at risk for metabolic syndrome (MetS).This study was a randomized, crossover, controlled feeding study. Participants (n = 101, ages 49.5 ± 1.2, BMI 29.4 ± 0.4 kg/mCanola (3.1 kg, P = 0.026) and CanolaOleic oil diets (3.09 kg, P = 0.03) reduced android fat mass compared with the Flax/Saff oil diet (3.2 kg), particularly in men. The decrease in abdominal fat mass was correlated with the reduction in blood pressure after the Canola (systolic blood pressure: r = 0.26, P = 0.062; diastolic blood pressure: r = 0.38, P = 0.0049) and CanolaOleic oil diets (systolic blood pressure: r = 0.39 P = 0.004; diastolic blood pressure: r = 0.45, P = 0.0006). The decrease in abdominal fat mass also was associated with a reduction in triglyceride levels after the CanolaOleic oil diet (r = 0.42, P = 0.002).Diets high in MUFA (compared with PUFA) reduced central obesity with an accompanying improvement in MetS risk factors. Diets high in MUFA may be beneficial for treating and perhaps preventing MetS.

Published
2016

16. Diets Low in Saturated Fat with Different Unsaturated Fatty Acid Profiles Similarly Increase Serum-Mediated Cholesterol Efflux from THP-1 Macrophages in a Population with or at Risk for Metabolic Syndrome: The Canola Oil Multicenter Intervention Trial

Author

Liu, Xiaoran, primary, Garban, Josephine, additional, Jones, Peter J, additional, Vanden Heuvel, Jack, additional, Lamarche, Benoît, additional, Jenkins, David J, additional, Connelly, Philip W, additional, Couture, Patrick, additional, Pu, Shuaihua, additional, Fleming, Jennifer A, additional, West, Sheila G, additional, and Kris-Etherton, Penny M, additional

Published
2018
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17. Abstract P382: Canola and High-Oleic Acid Canola Oils Improve Lipid/Lipoprotein Parameters Compared to an Oil Blend Characteristic of a Western Dietary Pattern in Individuals at Risk for Metabolic Syndrome: A Randomized Crossover Clinical Trial

Author

Bowen, Kate J, primary, Kris-Etherton, Penny M, additional, West, Sheila G, additional, Fleming, Jennifer A, additional, Connelly, Philip W, additional, Lamarche, Benoît, additional, Couture, Patrick, additional, Jenkins, David J, additional, Taylor, Carla, additional, Zahradka, Peter, additional, Hammad, Shatha S, additional, Sihag, Jyoti, additional, Chen, Xiang, additional, Guay, Valérie, additional, Maltais-Giguère, Julie, additional, Perera, Danielle, additional, Wilson, Angela, additional, Castillo, Sandra, additional, and Jones, Peter J, additional

Published
2018
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22. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity

Author

Liu, Xiaoran, primary, Kris-Etherton, Penny M., additional, West, Sheila G., additional, Lamarche, Benoît, additional, Jenkins, David J.A., additional, Fleming, Jennifer A., additional, McCrea, Cindy E., additional, Pu, Shuaihua, additional, Couture, Patrick, additional, Connelly, Philip W., additional, and Jones, Peter J.H., additional

Published
2016
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23. L-Arginine Supplementation Alleviates Postprandial Endothelial Dysfunction When Baseline Fasting Plasma Arginine Concentration Is Low: A Randomized Controlled Trial in Healthy Overweight Adults with Cardiometabolic Risk Factors

Author

Deveaux, Ambre, primary, Pham, Isabelle, additional, West, Sheila G, additional, André, Etienne, additional, Lantoine-Adam, Frédérique, additional, Bunouf, Pierre, additional, Sadi, Samira, additional, Hermier, Dominique, additional, Mathé, Véronique, additional, Fouillet, Hélène, additional, Huneau, Jean-François, additional, Benamouzig, Robert, additional, and Mariotti, François, additional

Published
2016
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26. Noninvasive assessment of hemodynamics

Author

Sauder, Katherine A., primary, Pokorney, Paige E., additional, McCrea, Cindy E., additional, Ulbrecht, Jan S., additional, Kris-Etherton, Penny M., additional, and West, Sheila G., additional

Published
2015
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27. Endothelial function, arterial stiffness and adherence to the 2010 Dietary Guidelines for Americans: a cross-sectional analysis

Author

Sauder, Katherine A., primary, Proctor, David N., additional, Chow, Mosuk, additional, Troy, Lisa M., additional, Wang, Na, additional, Vita, Joseph A., additional, Vasan, Ramachandran S., additional, Mitchell, Gary F., additional, Jacques, Paul F., additional, Hamburg, Naomi M., additional, and West, Sheila G., additional

Published
2015
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28. High-oleic canola oil consumption enriches LDL particle cholesteryl oleate content and reduces LDL proteoglycan binding in humans

Author

Jones, Peter J.H., primary, MacKay, Dylan S., additional, Senanayake, Vijitha K., additional, Pu, Shuaihua, additional, Jenkins, David J.A., additional, Connelly, Philip W., additional, Lamarche, Benoît, additional, Couture, Patrick, additional, Kris-Etherton, Penny M., additional, West, Sheila G., additional, Liu, Xiaoran, additional, Fleming, Jennifer A., additional, Hantgan, Roy R., additional, and Rudel, Lawrence L., additional

Published
2015
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29. Effects of culinary spices and psychological stress on postprandial lipemia and lipase activity: results of a randomized crossover study and in vitro experiments

Author

McCrea, Cindy E, primary, West, Sheila G, additional, Kris-Etherton, Penny M, additional, Lambert, Joshua D, additional, Gaugler, Trent L, additional, Teeter, Danette L, additional, Sauder, Katherine A, additional, Gu, Yeyi, additional, Glisan, Shannon L, additional, and Skulas-Ray, Ann C, additional

Published
2015
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31. Acute Peanut Consumption Alters Postprandial Lipids and Vascular Responses in Healthy Overweight or Obese Men.

Author

Xiaoran Liu, Hill, Alison M., West, Sheila G., Gabauer, Rachel M., McCrea, Cindy E., Fleming, Jennifer A., Kris-Etherton, Penny M., and Liu, Xiaoran

Subjects
HYPERLIPIDEMIA, HYPERLIPIDEMIA treatment, OBESITY in men, OBESITY treatment, LIPID analysis, PATIENTS, BEVERAGES, BLOOD sugar, COMPARATIVE studies, DIET, ENDOTHELIUM, FAT content of food, HIGH density lipoproteins, INGESTION, INSULIN, LIPIDS, LOW density lipoproteins, RESEARCH methodology, MEDICAL cooperation, NUTS, OBESITY, RESEARCH, RESEARCH funding, SEEDS, TRIGLYCERIDES, EVALUATION research, BRACHIAL artery, RANDOMIZED controlled trials, PREVENTION
Abstract

Background: Postprandial hyperlipidemia is associated with impaired endothelial function. Peanut consumption favorably affects the lipid and lipoprotein profile; however, the effects on endothelial function remain unclear.Objective: The purpose of the study was to evaluate the effects of acute peanut consumption as part of a high-fat meal on postprandial endothelial function.Methods: We conducted a randomized, controlled, crossover postprandial study to evaluate the effect of acute peanut consumption on postprandial lipids and endothelial function as assessed by flow-mediated dilatation (FMD) of the brachial artery in 15 healthy overweight or obese men [mean age: 26.7 y; mean body mass index (in kg/m2): 31.4]. Participants consumed, in a randomized order, a peanut meal containing 3 ounces (85 g) ground peanuts (1198 kcal; 40.0% carbohydrate, 47.7% fat, 19.4% saturated fat, 13.2% protein) and a control meal matched for energy and macronutrient content. Meals were in the form of a shake, scheduled ≥1 wk apart. Lipids, lipoproteins, glucose, and insulin were measured at baseline (0 min) and at 30, 60, 120, and 240 min after shake consumption. FMD was measured at baseline and at 240 min.Results: Acute peanut consumption blunted the serum triglyceride (TG) response 120 and 240 min after consumption compared with the control meal (means ± SEMs-120 min: 188.9 ± 19.4 compared with 197.5 ± 20.7 mg/dL; 240 min: 189.9 ± 24.3 compared with 197.3 ± 18.4 mg/dL; P < 0.05 for both). Total, LDL, and HDL cholesterol and glucose and insulin responses were similar between the test meals. Compared with baseline, only the control meal significantly decreased FMD at 240 min (control: -1.2% ± 0.5%; P = 0.029; peanut: -0.6% ± 0.5%; P = 0.3). Participants with higher baseline total (>150 mg/dL) and LDL (>100 mg/dL)-cholesterol concentrations showed a significant decrease in FMD after the control meal (-1.8%, P = 0.017; -2.0%, P = 0.038), whereas the peanut meal maintained endothelial function in all participants irrespective of total- and LDL-cholesterol concentrations.Conclusion: The inclusion of 85 g peanuts (3 ounces) as part of a high-fat meal improved the postprandial TG response and preserved endothelial function in healthy overweight or obese men. This trial was registered at clinicaltrials.gov as NCT01405300. [ABSTRACT FROM AUTHOR]

Published
2017
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34. A moderate-fat diet containing pistachios improves emerging markers of cardiometabolic syndrome in healthy adults with elevated LDL levels.

Author

Holligan, Simone D., West, Sheila G., Gebauer, Sarah K., Kay, Colin D., and Kris-Etherton, Penny M.

Subjects
NUTS, BLOOD pressure, BLOOD sugar, C-reactive protein, CHOLESTEROL, CROSSOVER trials, HIGH density lipoproteins, INSULIN resistance, LOW density lipoproteins, HEALTH outcome assessment, PROBABILITY theory, RESEARCH funding, STEROLS, TRIGLYCERIDES, RANDOMIZED controlled trials, TREATMENT effectiveness, DATA analysis software, THERAPEUTICS
Abstract

A randomised, cross-over, controlled-feeding study was conducted to evaluate the cholesterol-lowering effects of diets containing pistachios as a strategy for increasing total fat (TF) levels v. a control (step I) lower-fat diet. Ex vivo techniques were used to evaluate the effects of pistachio consumption on lipoprotein subclasses and functionality in individuals (n 28) with elevated LDL levels ( ≥ 2·86 mmol/l). The following test diets (SFA approximately 8 % and cholesterol < 300 mg/d) were used: a control diet (25 % TF); a diet comprising one serving of pistachios per d (1PD; 30 % TF); a diet comprising two servings of pistachios per d (2PD; 34 % TF). A significant decrease in small and dense LDL (sdLDL) levels was observed following the 2PD dietary treatment v. the 1PD dietary treatment (P= 0·03) and following the 2PD dietary treatment v. the control treatment (P= 0·001). Furthermore, reductions in sdLDL levels were correlated with reductions in TAG levels (r 0·424, P= 0·025) following the 2PD dietary treatment v. the control treatment. In addition, inclusion of pistachios increased the levels of functional α-1 (P= 0·073) and α-2 (P= 0·056) HDL particles. However, ATP-binding cassette transporter A1-mediated serum cholesterol efflux capacity (P= 0·016) and global serum cholesterol efflux capacity (P= 0·076) were only improved following the 2PD dietary treatment v. the 1PD dietary treatment when baseline C-reactive protein status was low ( < 103μg/l). Moreover, a significant decrease in the TAG:HDL ratio was observed following the 2PD dietary treatment v. the control treatment (P= 0·036). There was a significant increase in β-sitosterol levels (P< 0·0001) with the inclusion of pistachios, confirming adherence to the study protocol. In conclusion, the inclusion of pistachios in a moderate-fat diet favourably affects the cardiometabolic profile in individuals with an increased risk of CVD. [ABSTRACT FROM PUBLISHER]

Published
2014
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35. Acute Peanut Consumption Alters Postprandial Lipids and Vascular Responses in Healthy Overweight or Obese Men

Author

Penny M. Kris-Etherton, Cindy E McCrea, Rachel M Gabauer, Sheila G. West, Xiaoran Liu, Jennifer A Fleming, Alison M. Hill, Liu, Xiaoran, Hill, Alison M, West, Sheila G, Gabauer, Rachel M, McCrea, Cindy E, Fleming, Jennifer A, and Kris-Etherton, Penny M

Subjects
Blood Glucose, Male, Arachis, Brachial Artery, Nutrition and Disease, Saturated fat, Medicine (miscellaneous), 030204 cardiovascular system & hematology, Overweight, chemistry.chemical_compound, 0302 clinical medicine, Hyperlipidemia, Insulin, peanuts, 10. No inequality, Meals, triglycerides, 2. Zero hunger, postprandial responses, Meal, Nutrition and Dietetics, Postprandial Period, Lipids, Postprandial, Seeds, medicine.symptom, Adult, medicine.medical_specialty, Hyperlipidemias, 030209 endocrinology & metabolism, nuts, vascular function, Beverages, 03 medical and health sciences, Internal medicine, medicine, Humans, overweight, Obesity, Nutrition & Dietetics, Triglyceride, business.industry, Cholesterol, HDL, Cholesterol, LDL, medicine.disease, Dietary Fats, Diet, Endocrinology, chemistry, Endothelium, Vascular, business, Body mass index, Lipoprotein
Abstract

Background: Postprandial hyperlipidemia is associated with impaired endothelial function. Peanut consumption favorably affects the lipid and lipoprotein profile; however, the effects on endothelial function remain unclear. Objective: The purpose of the study was to evaluate the effects of acute peanut consumption as part of a high-fat meal on postprandial endothelial function. Methods: We conducted a randomized, controlled, crossover postprandial study to evaluate the effect of acute peanut consumption on postprandial lipids and endothelial function as assessed by flow-mediated dilatation (FMD) of the brachial artery in 15 healthy overweight or obese men [mean age: 26.7 y; mean body mass index (in kg/m2): 31.4]. Participants consumed, in a randomized order, a peanut meal containing 3 ounces (85 g) ground peanuts (1198 kcal; 40.0% carbohydrate, 47.7% fat, 19.4% saturated fat, 13.2% protein) and a control meal matched for energy and macronutrient content. Meals were in the form of a shake, scheduled ≥1 wk apart. Lipids, lipoproteins, glucose, and insulin were measured at baseline (0 min) and at 30, 60, 120, and 240 min after shake consumption. FMD was measured at baseline and at 240 min. Results: Acute peanut consumption blunted the serum triglyceride (TG) response 120 and 240 min after consumption compared with the control meal (means ± SEMs—120 min: 188.9 ± 19.4 compared with 197.5 ± 20.7 mg/dL; 240 min: 189.9 ± 24.3 compared with 197.3 ± 18.4 mg/dL; P < 0.05 for both). Total, LDL, and HDL cholesterol and glucose and insulin responses were similar between the test meals. Compared with baseline, only the control meal significantly decreased FMD at 240 min (control: −1.2% ± 0.5%; P = 0.029; peanut: −0.6% ± 0.5%; P = 0.3). Participants with higher baseline total (>150 mg/dL) and LDL (>100 mg/dL)-cholesterol concentrations showed a significant decrease in FMD after the control meal (−1.8%, P = 0.017; −2.0%, P = 0.038), whereas the peanut meal maintained endothelial function in all participants irrespective of total- and LDL-cholesterol concentrations. Conclusion: The inclusion of 85 g peanuts (3 ounces) as part of a high-fat meal improved the postprandial TG response and preserved endothelial function in healthy overweight or obese men. This trial was registered at clinicaltrials.gov as NCT01405300.

Published
2017

36. Type and amount of dietary protein in the treatment of metabolic syndrome: A randomized controlled trial

Author

Kristina Harris Jackson, Michael A. Roussell, Alison M. Hill, Sheila G. West, Penny M. Kris-Etherton, Hill, Alison M, Jackson, Kristina A, Roussell, Michael A, West, Sheila G, and Kris-Etherton, Penny M

Subjects
medicine.medical_specialty, Calorie, DASH diet, 030309 nutrition & dietetics, Medicine (miscellaneous), 030204 cardiovascular system & hematology, Overweight, Biology, metabolic syndrome, 03 medical and health sciences, 0302 clinical medicine, dietary protein, Weight loss, Internal medicine, Dash, medicine, 2. Zero hunger, 0303 health sciences, body composition, Nutrition and Dietetics, medicine.disease, Obesity, 3. Good health, Endocrinology, Plant protein, Population study, medicine.symptom, weight loss, lean beef
Abstract

Background: Food-based dietary patterns emphasizing plant protein that were evaluated in the Dietary Approaches to Stop Hypertension (DASH) and OmniHeart trials are recommended for the treatment of metabolic syndrome (MetS). However, the contribution of plant protein to total protein in these diets is proportionally less than that of animal protein. Objective: This study compared 3 diets varying in type (animal compared with plant) and amount of protein on MetS criteria. Design: Sixty-two overweight adults with MetS consumed a healthy American diet for 2 wk before being randomly allocated to either a modified DASH diet rich in plant protein (18% protein, two-thirds plant sources, n = 9 males, 12 females), a modified DASH diet rich in animal protein (Beef in an Optimal Lean Diet: 18.4% protein, two-thirds animal sources, n = 9 males, 11 females), or a moderate-protein diet (Beef in an Optimal Lean Diet Plus Protein: 27% protein, two-thirds animal sources, n = 10 males, 11 females). Diets were compared across 3 phases of energy balance: 5 wk of controlled (all foods provided) weight maintenance (WM), 6 wk of controlled weight loss (minimum 500-kcal/d deficit) including exercise (WL), and 12 wk of prescribed, free-living weight loss (FL). The primary endpoint was change in MetS criteria. Results: All groups achieved ∼5% weight loss at the end of the WL phase and maintained it through FL, with no between-diet differences (WM compared with WL, FL, P < 0.0001; between diets, P = NS). All MetS criteria decreased independent of diet composition (main effect of phase, P < 0.01; between diets, P = NS). After WM, all groups had a MetS prevalence of 80–90% [healthy American diet (HAD) compared with WM, P = NS], which decreased to 50–60% after WL and was maintained through FL (HAD, WM vs WL, FL, P < 0.01). Conclusions: Weight loss was the primary modifier of MetS resolution in our study population regardless of protein source or amount. Our findings demonstrate that heart-healthy weight-loss dietary patterns that emphasize either animal or plant protein improve MetS criteria similarly. This study was registered at clinicaltrials.gov as {"type":"clinical-trial","attrs":{"text":"NCT00937638","term_id":"NCT00937638"}}NCT00937638.

Published
2015

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