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1. Fertility Preservation

Author

Patrizio, Pasquale, Molinari, Emanuela, Falcone, Tommaso, Westphal, Lynn M., Falcone, Tommaso, editor, and Hurd, William W., editor

Published
2022
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2. The National Physicians Cooperative: transforming fertility management in the cancer setting and beyond

Author

Smith, Brigid M, Duncan, Francesca E, Ataman, Lauren, Smith, Kristin, Quinn, Gwendolyn P, Chang, R Jeffrey, Finlayson, Courtney, Orwig, Kyle, Valli-Pulaski, Hanna, Moravek, Molly B, Zelinski, Mary B, Su, H Irene, Vitek, Wendy, Smith, James F, Jeruss, Jacqueline S, Gracia, Clarisa, Coutifaris, Christos, Shah, Divya, Nahata, Leena, Gomez-Lobo, Veronica, Appiah, Leslie Coker, Brannigan, Robert E, Gillis, Valerie, Gradishar, William, Javed, Asma, Rhoton-Vlasak, Alice S, Kondapalli, Laxmi A, Neuber, Evelyn, Ginsberg, Jill P, Muller, Charles H, Hirshfeld-Cytron, Jennifer, Kutteh, William H, Lindheim, Steven R, Cherven, Brooke, Meacham, Lillian R, Rao, Pooja, Torno, Lilibeth, Sender, Leonard S, Vadaparampil, Susan T, Skiles, Jodi L, Schafer-Kalkhoff, Tara, Frias, Oliva J, Byrne, Julia, Westphal, Lynn M, Schust, Danny J, Klosky, James L, McCracken, Kate A, Ting, Alison, Khan, Zaraq, Granberg, Candace, Lockart, Barbara, Scoccia, Bert, Laronda, Monica M, Mersereau, Jennifer E, Marsh, Courtney, Pavone, Mary Ellen, and Woodruff, Teresa K

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Contraception/Reproduction, Cancer, Prevention, Reproductive health and childbirth, Good Health and Well Being, Adult, Antineoplastic Agents, Behavioral Medicine, Child, Disease Progression, Endocrinology, Female, Fertility, Fertility Preservation, Gynecology, Humans, Intersectoral Collaboration, Medical Oncology, Neoplasms, Obstetrics, Physicians, Practice Guidelines as Topic, Pregnancy, Quality of Life, United States, Urology, fertility preservation, oncofertility, reproductive health, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Once unimaginable, fertility management is now a nationally established part of cancer care in institutions, from academic centers to community hospitals to private practices. Over the last two decades, advances in medicine and reproductive science have made it possible for men, women and children to be connected with an oncofertility specialist or offered fertility preservation soon after a cancer diagnosis. The Oncofertility Consortium's National Physicians Cooperative is a large-scale effort to engage physicians across disciplines - oncology, urology, obstetrics and gynecology, reproductive endocrinology, and behavioral health - in clinical and research activities to enable significant progress in providing fertility preservation options to children and adults. Here, we review the structure and function of the National Physicians Cooperative and identify next steps.

Published
2018

3. A View from the past into our collective future: the oncofertility consortium vision statement

Author

Woodruff, Teresa K., Ataman-Millhouse, Lauren, Acharya, Kelly S., Almeida-Santos, Teresa, Anazodo, Antoinette, Anderson, Richard A., Appiah, Leslie, Bader, Joy, Becktell, Kerri, Brannigan, Robert E., Breech, Lesley, Bourlon, Maria T., Bumbuliene, Žana, Burns, Karen, Campo-Engelstein, Lisa, Campos, Jacira R., Centola, Grace M., Chehin, Mauricio Barbour, Chen, Diane, De Vos, Michel, Duncan, Francesca E., El-Damen, Ahmed, Fair, Douglas, Famuyiwa, Yemi, Fechner, Patricia Y., Fontoura, Paula, Frias, Olivia, Gerkowicz, Sabrina A., Ginsberg, Jill, Gracia, Clarisa R., Goldman, Kara, Gomez-Lobo, Veronica, Hazelrigg, Brent, Hsieh, Michael H., Hoyos, Luis R., Hoyos-Martinez, Alfonso, Jach, Robert, Jassem, Jacek, Javed, Murid, Jayasinghe, Yasmin, Jeelani, Roohi, Jeruss, Jacqueline S., Kaul-Mahajan, Nalini, Keim-Malpass, Jessica, Ketterl, Tyler G., Khrouf, Mohamed, Kimelman, Dana, Kusuhara, Atsuko, Kutteh, William H., Laronda, Monica M., Lee, Jung Ryeol, Lehmann, Vicky, Letourneau, Joseph M., McGinnis, Lynda K, McMahon, Eileen, Meacham, Lillian R., Mijangos, Monserrat Fabiola Velez, Moravek, Molly, Nahata, Leena, Ogweno, George Moses, Orwig, Kyle E., Pavone, Mary Ellen, Peccatori, Fedro Alessandro, Pesce, Romina Ileana, Pulaski, Hanna, Quinn, Gwendolyn, Quintana, Ramiro, Quintana, Tomas, de Carvalho, Bruno Ramalho, Ramsey-Goldman, Rosalind, Reinecke, Joyce, Reis, Fernando M., Rios, Julie, Rhoton-Vlasak, Alice S., Rodriguez-Wallberg, Kenny A., Roeca, Cassandra, Rotz, Seth J., Rowell, Erin, Salama, Mahmoud, Saraf, Amanda J., Scarella, Anibal, Schafer-Kalkhoff, Tara, Schmidt, Deb, Senapati, Suneeta, Shah, Divya, Shikanov, Ariella, Shnorhavorian, Margarett, Skiles, Jodi L., Smith, James F., Smith, Kristin, Sobral, Fabio, Stimpert, Kyle, Su, H. Irene, Sugimoto, Kouhei, Suzuki, Nao, Thakur, Mili, Victorson, David, Viale, Luz, Vitek, Wendy, Wallace, W. Hamish, Wartella, Ellen A., Westphal, Lynn M., Whiteside, Stacy, Wilcox, Lea H., Wyns, Christine, Xiao, Shuo, Xu, Jing, and Zelinski, Mary

Published
2021
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4. Embryo and Oocyte Banking

Author

Westphal, Lynn M., Massie, Jamie A. M., Lentscher, Jessica A., Woodruff, Teresa K., editor, Shah, Divya K., editor, and Vitek, Wendy S., editor

Published
2019
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7. Fertility Preservation

Author

Patrizio, Pasquale, Molinari, Emanuela, Falcone, Tommaso, Westphal, Lynn M., Falcone, Tommaso, editor, and Hurd, William W., editor

Published
2017
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12. Installing oncofertility programs for common cancers in optimum resource settings (Repro-Can-OPEN Study Part II): a committee opinion

Author

Mahmoud, Salama, Mitchell, Rod T, Laronda, Monica M., Goldman, Kara, Smith, Kristen, Pavone, Mary Ellen, Brannigan, Robert E., Ataman-Millhouse, Laura, Patrizio, Pasquale, Rodriguez-Wallberg, Kenny A., Okutsu-Horage, Yuki, Susuki, Nao, Lambertini, Matteo, Stern, Catharyn, Gomez-Lobo, Veronica, Maher, Jacqueline Y, Hsieh, M., Moravek, Molly, Anazodo, Antoinette, Westphal, Lynn M., Anderson, Richard A, Wallace, W Hamish B, Nahata, Leena, Whiteside, Stacy, Senapati, Suneeta, Shah, Divya K, Gracia, Clarisa R., Fino, Elizabeth M, Blakemore, Jennifer K, Quinn, Gwendolyn P, Krüssel, Jan-Steffen, Baston-Büst, Dunja-Maria, Liebenthron, Jana, Andersen, Claus Y, Kristensen, Stine Gry, Mamsen, Linn S, Jayasinghe, Yasmin, Su, Irene H, Dolmans, M. M., Dolmans, christiani A, Demeestere, Isabelle, De Vos, Isabelle, Van Moer, E., Isachenko, Vladimir, Isachenko, Evgenia, Mallmann, Peter, Rahimi, Gohar, Valli-pulaski, H, Steimer, S, McMahon, Katherine V., Orwig, Kyle E, Sroga, Julie, Smith, James F., Mok-Lin, Evelyn, Woodruff, Teresa K, UCL - SSS/IREC/GYNE - Pôle de Gynécologie, UCL - (SLuc) Service de gynécologie et d'andrologie, Surgical clinical sciences, Follicle Biology, and Centre for Reproductive Medicine - Gynaecology

Subjects
Male, Lymphoma, Best practice, Optimum resource settings, oncofertility, Oncofertility, breast cancer, Breast cancer, Japan, Neoplasms, Genetics, LYMPHOMA, Humans, Genetics (clinical), Cancer, Leukemia, leukemia, Obstetrics and Gynecology, Fertility Preservation, General Medicine, In Vitro Oocyte Maturation Techniques, Europe, oncology, Oocytes, Female, Childhood cancer, Developmental Biology, reproductive medicine
Abstract

PURPOSE: The main objective of Repro-Can-OPEN Study Part 2 is to learn more about oncofertility practices in optimum resource settings to provide a roadmap to establish oncofertility best practice models. METHODS: As an extrapolation for oncofertility best practice models in optimum resource settings, we surveyed 25 leading and well-resourced oncofertility centers and institutions from the USA, Europe, Australia, and Japan. The survey included questions on the availability and degree of utilization of fertility preservation options in case of childhood cancer, breast cancer, and blood cancer. RESULTS: All surveyed centers responded to all questions. Responses and their calculated oncofertility scores showed three major characteristics of oncofertility practice in optimum resource settings: (1) strong utilization of sperm freezing, egg freezing, embryo freezing, ovarian tissue freezing, gonadal shielding, and fractionation of chemo- and radiotherapy; (2) promising utilization of GnRH analogs, oophoropexy, testicular tissue freezing, and oocyte in vitro maturation (IVM); and (3) rare utilization of neoadjuvant cytoprotective pharmacotherapy, artificial ovary, in vitro spermatogenesis, and stem cell reproductive technology as they are still in preclinical or early clinical research settings. Proper technical and ethical concerns should be considered when offering advanced and experimental oncofertility options to patients. CONCLUSIONS: Our Repro-Can-OPEN Study Part 2 proposed installing specific oncofertility programs for common cancers in optimum resource settings as an extrapolation for best practice models. This will provide efficient oncofertility edification and modeling to oncofertility teams and related healthcare providers around the globe and help them offer the best care possible to their patients.

Published
2021
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14. A View from the past into our collective future: the oncofertility consortium vision statement.

Author

UCL - SSS/IREC/GYNE - Pôle de Gynécologie, UCL - (SLuc) Service de gynécologie et d'andrologie, Woodruff, Teresa K, Ataman-Millhouse, Lauren, Acharya, Kelly S, Almeida-Santos, Teresa, Anazodo, Antoinette, Anderson, Richard A, Appiah, Leslie, Bader, Joy, Becktell, Kerri, Brannigan, Robert E, Breech, Lesley, Bourlon, Maria T, Bumbuliene, Žana, Burns, Karen, Campo-Engelstein, Lisa, Campos, Jacira R, Centola, Grace M, Chehin, Mauricio Barbour, Chen, Diane, De Vos, Michel, Duncan, Francesca E, El-Damen, Ahmed, Fair, Douglas, Famuyiwa, Yemi, Fechner, Patricia Y, Fontoura, Paula, Frias, Olivia, Gerkowicz, Sabrina A, Ginsberg, Jill, Gracia, Clarisa R, Goldman, Kara, Gomez-Lobo, Veronica, Hazelrigg, Brent, Hsieh, Michael H, Hoyos, Luis R, Hoyos-Martinez, Alfonso, Jach, Robert, Jassem, Jacek, Javed, Murid, Jayasinghe, Yasmin, Jeelani, Roohi, Jeruss, Jacqueline S, Kaul-Mahajan, Nalini, Keim-Malpass, Jessica, Ketterl, Tyler G, Khrouf, Mohamed, Kimelman, Dana, Kusuhara, Atsuko, Kutteh, William H, Laronda, Monica M, Lee, Jung Ryeol, Lehmann, Vicky, Letourneau, Joseph M, McGinnis, Lynda K, McMahon, Eileen, Meacham, Lillian R, Mijangos, Monserrat Fabiola Velez, Moravek, Molly, Nahata, Leena, Ogweno, George Moses, Orwig, Kyle E, Pavone, Mary Ellen, Peccatori, Fedro Alessandro, Pesce, Romina Ileana, Pulaski, Hanna, Quinn, Gwendolyn, Quintana, Ramiro, Quintana, Tomas, de Carvalho, Bruno Ramalho, Ramsey-Goldman, Rosalind, Reinecke, Joyce, Reis, Fernando M, Rios, Julie, Rhoton-Vlasak, Alice S, Rodriguez-Wallberg, Kenny A, Roeca, Cassandra, Rotz, Seth J, Rowell, Erin, Salama, Mahmoud, Saraf, Amanda J, Scarella, Anibal, Schafer-Kalkhoff, Tara, Schmidt, Deb, Senapati, Suneeta, Shah, Divya, Shikanov, Ariella, Shnorhavorian, Margarett, Skiles, Jodi L, Smith, James F, Smith, Kristin, Sobral, Fabio, Stimpert, Kyle, Su, H Irene, Sugimoto, Kouhei, Suzuki, Nao, Thakur, Mili, Victorson, David, Viale, Luz, Vitek, Wendy, Wallace, W Hamish, Wartella, Ellen A, Westphal, Lynn M, Whiteside, Stacy, Wilcox, Lea H, Wyns, Christine, Xiao, Shuo, Xu, Jing, Zelinski, Mary, UCL - SSS/IREC/GYNE - Pôle de Gynécologie, UCL - (SLuc) Service de gynécologie et d'andrologie, Woodruff, Teresa K, Ataman-Millhouse, Lauren, Acharya, Kelly S, Almeida-Santos, Teresa, Anazodo, Antoinette, Anderson, Richard A, Appiah, Leslie, Bader, Joy, Becktell, Kerri, Brannigan, Robert E, Breech, Lesley, Bourlon, Maria T, Bumbuliene, Žana, Burns, Karen, Campo-Engelstein, Lisa, Campos, Jacira R, Centola, Grace M, Chehin, Mauricio Barbour, Chen, Diane, De Vos, Michel, Duncan, Francesca E, El-Damen, Ahmed, Fair, Douglas, Famuyiwa, Yemi, Fechner, Patricia Y, Fontoura, Paula, Frias, Olivia, Gerkowicz, Sabrina A, Ginsberg, Jill, Gracia, Clarisa R, Goldman, Kara, Gomez-Lobo, Veronica, Hazelrigg, Brent, Hsieh, Michael H, Hoyos, Luis R, Hoyos-Martinez, Alfonso, Jach, Robert, Jassem, Jacek, Javed, Murid, Jayasinghe, Yasmin, Jeelani, Roohi, Jeruss, Jacqueline S, Kaul-Mahajan, Nalini, Keim-Malpass, Jessica, Ketterl, Tyler G, Khrouf, Mohamed, Kimelman, Dana, Kusuhara, Atsuko, Kutteh, William H, Laronda, Monica M, Lee, Jung Ryeol, Lehmann, Vicky, Letourneau, Joseph M, McGinnis, Lynda K, McMahon, Eileen, Meacham, Lillian R, Mijangos, Monserrat Fabiola Velez, Moravek, Molly, Nahata, Leena, Ogweno, George Moses, Orwig, Kyle E, Pavone, Mary Ellen, Peccatori, Fedro Alessandro, Pesce, Romina Ileana, Pulaski, Hanna, Quinn, Gwendolyn, Quintana, Ramiro, Quintana, Tomas, de Carvalho, Bruno Ramalho, Ramsey-Goldman, Rosalind, Reinecke, Joyce, Reis, Fernando M, Rios, Julie, Rhoton-Vlasak, Alice S, Rodriguez-Wallberg, Kenny A, Roeca, Cassandra, Rotz, Seth J, Rowell, Erin, Salama, Mahmoud, Saraf, Amanda J, Scarella, Anibal, Schafer-Kalkhoff, Tara, Schmidt, Deb, Senapati, Suneeta, Shah, Divya, Shikanov, Ariella, Shnorhavorian, Margarett, Skiles, Jodi L, Smith, James F, Smith, Kristin, Sobral, Fabio, Stimpert, Kyle, Su, H Irene, Sugimoto, Kouhei, Suzuki, Nao, Thakur, Mili, Victorson, David, Viale, Luz, Vitek, Wendy, Wallace, W Hamish, Wartella, Ellen A, Westphal, Lynn M, Whiteside, Stacy, Wilcox, Lea H, Wyns, Christine, Xiao, Shuo, Xu, Jing, and Zelinski, Mary

Abstract

Today, male and female adult and pediatric cancer patients, individuals transitioning between gender identities, and other individuals facing health extending but fertility limiting treatments can look forward to a fertile future. This is, in part, due to the work of members associated with the Oncofertility Consortium. The Oncofertility Consortium is an international, interdisciplinary initiative originally designed to explore the urgent unmet need associated with the reproductive future of cancer survivors. As the strategies for fertility management were invented, developed or applied, the individuals for who the program offered hope, similarly expanded. As a community of practice, Consortium participants share information in an open and rapid manner to addresses the complex health care and quality-of-life issues of cancer, transgender and other patients. To ensure that the organization remains contemporary to the needs of the community, the field designed a fully inclusive mechanism for strategic planning and here present the findings of this process. This interprofessional network of medical specialists, scientists, and scholars in the law, medical ethics, religious studies and other disciplines associated with human interventions, explore the relationships between health, disease, survivorship, treatment, gender and reproductive longevity. The goals are to continually integrate the best science in the service of the needs of patients and build a community of care that is ready for the challenges of the field in the future.

Published
2021

19. Results of a pilot study in the U.S. and Vietnam to assess the utility and acceptability of a multi-level pregnancy test (MLPT) for home monitoring of hCG trends after assisted reproduction

Author

Shochet, Tara, primary, Comstock, Ioanna A., additional, Ngoc, Nguyen Thi Nhu, additional, Westphal, Lynn M., additional, Sheldon, Wendy R., additional, Loc, Ly Thai, additional, Blum, Jennifer, additional, Winikoff, Beverly, additional, and Blumenthal, Paul D., additional

Published
2017
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20. Medical egg freezing: the importance of a patient-centered approach to fertility preservation.

Author

Inhorn, Marcia C., Birenbaum-Carmeli, Daphna, Westphal, Lynn M., Doyle, Joseph, Gleicher, Norbert, Meirow, Dror, Raanani, Hila, Dirnfeld, Martha, and Patrizio, Pasquale

Subjects
FERTILITY preservation, OVUM cryopreservation, PATIENT-centered care, ANTHROPOLOGISTS in medicine, MOTIVATION (Psychology)
Abstract

Purpose: This binational qualitative study of medical egg freezing (MEF) examined women's motivations and experiences, including their perceived needs for patient-centered care in the midst of fertility- and life-threatening diagnoses. Methods: Forty-five women who had undertaken MEF were interviewed in the USA (33 women) and in Israel (12 women) between June 2014 and August 2016. Interviews lasted approximately 1 h and were conducted by two senior medical anthropologists, one in each country. Women were recruited from four American IVF clinics (two academic, two private) and two Israeli clinics (both academic) where MEF is being offered to cancer patients and women with other fertility-threatening medical conditions. Results: Women who undertake MEF view their fertility and future motherhood as important components of their identities and recovery and, thus, are grateful for the opportunity to pursue fertility preservation. However, women who undergo MEF have special needs, given that they tend to be a 'vulnerable' population of young (age < 30), unmarried, resource-constrained women, who are facing not only fertility loss but also the 'double jeopardy' of cancer. Through in-depth, qualitative interviews, these women's MEF stories reveal 10 dimensions of care important to fertility preservation, including five 'system factors' (information, coordination and integration, accessibility, physical comfort, cost) and five 'human factors' (adolescent issues, male partner involvement, family involvement, egg disposition decisions, emotional support). Together, these dimensions of care constitute an important framework that can be best described as 'patient-centered MEF.' Conclusions: Women pursuing MEF have special medical needs and concerns, which require particular forms of patient-centered care. This study outlines 10 dimensions of patient-centered fertility preservation that are appropriate for MEF patients. This approach may help IVF clinics to be better prepared for delivering top-quality care to mostly young, single women facing the daunting prospect of fertility loss and life-threatening medical diagnoses. [ABSTRACT FROM AUTHOR]

Published
2018
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