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Your search keyword '"Xiao, Yueyuan"' showing total 15 results
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15 results on '"Xiao, Yueyuan"'

10. Isomeric Oligo(Phenylenevinylene)‐Based Covalent Organic Frameworks with Different Orientation of Imine Bonds and Distinct Photocatalytic Activities.

Author

Dong, Wenbo, Qin, Zhiying, Wang, Kuixing, Xiao, Yueyuan, Liu, Xiangyang, Ren, Shijie, and Li, Longyu

Subjects
PHOTOCATALYSTS, CHARGE exchange, VITAMIN C, TRIAZINES, PROTON transfer reactions, PHOTOELECTRIC effect, PHOTOCATALYSIS
Abstract

Imine‐linked covalent organic frameworks (COFs) have been extensively studied in photocatalysis because of their easy synthesis and excellent crystallinity. The effect of imine‐bond orientation on the photocatalytic properties of COFs, however, is still rarely studied. Herein, we report two novel COFs with different orientations of imine bonds using oligo(phenylenevinylene) moieties. The COFs showed similar structures but great differences in their photoelectric properties. COF‐932 demonstrated a superior hydrogen evolution performance compared to COF‐923 when triethanolamine was used as the sacrificial agent. Interestingly, the use of ascorbic acid led to the protonation of the COFs, further altering the direction of electron transfer. The photocatalytic performances were increased to 23.4 and 0.73 mmol g−1 h−1 for protonated COF‐923 and COF‐932, respectively. This study provides a clear strategy for the design of imine‐linked COF‐based photocatalysts and advances the development of COFs. [ABSTRACT FROM AUTHOR]

Published
2023
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11. miR-203 promotes HaCaT cell overproliferation through targeting LXR-α and PPAR-γ

Author

Xiao, Yueyuan, Wang, Haizhen, Wang, Chang, Zeng, Bijun, Tang, Xueyong, Zhang, Yujin, Peng, Youhua, Luo, Meijunzi, Huang, Pan, and Yang, Zhibo

Subjects
lipids (amino acids, peptides, and proteins)
Abstract

Psoriasis is an immune-mediated chronic inflammatory skin disease. Keratinocyte hyperproliferation has been regarded as a significant event in psoriasis pathogenesis. Considering the vital role of miRNA-mediated mRNA repression in psoriasis pathogenesis, in the present study, we attempted to investigate the mechanism of keratinocyte overproliferation from the point of miRNA-mRNA regulation. Both online microarray expression profiles and experimental results indicated that the expression of LXR-α and PPAR-γ was downregulated in psoriasis lesion skin. LXR-α or PPAR-γ overexpression alone was sufficient to inhibit keratinocyte proliferation, decrease KRT5 and KRT14 protein levels and increase KRT1 and KRT10 protein levels. miR-203 negatively regulated LXR-α and PPAR-γ expression through direct targeting. miR-203 inhibition exerted the opposite effects to LXR-α or PPAR-γ overexpression on HaCaT cells. More importantly, LXR-α or PPAR-γ overexpression could markedly remarkably attenuate the effects of miR-203 overexpression in keratinocytes, indicating that miR-203 promotes keratinocyte proliferation by targeting LXR-α and PPAR-γ. In conclusion, the miR-203-LXR-α/PPAR-γ axis modulates the proliferation of keratinocytes and might be a novel target for psoriasis treatment, which needs further in vivo investigation.

Published
2020
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15. Isomeric Oligo(Phenylenevinylene)-Based Covalent Organic Frameworks with Different Orientation of Imine Bonds and Distinct Photocatalytic Activities.

Author

Dong W, Qin Z, Wang K, Xiao Y, Liu X, Ren S, and Li L

Abstract

Imine-linked covalent organic frameworks (COFs) have been extensively studied in photocatalysis because of their easy synthesis and excellent crystallinity. The effect of imine-bond orientation on the photocatalytic properties of COFs, however, is still rarely studied. Herein, we report two novel COFs with different orientations of imine bonds using oligo(phenylenevinylene) moieties. The COFs showed similar structures but great differences in their photoelectric properties. COF-932 demonstrated a superior hydrogen evolution performance compared to COF-923 when triethanolamine was used as the sacrificial agent. Interestingly, the use of ascorbic acid led to the protonation of the COFs, further altering the direction of electron transfer. The photocatalytic performances were increased to 23.4 and 0.73 mmol g -1  h -1 for protonated COF-923 and COF-932, respectively. This study provides a clear strategy for the design of imine-linked COF-based photocatalysts and advances the development of COFs., (© 2022 Wiley-VCH GmbH.)

Published
2023
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