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Your search keyword '"Yuan, Xiaomeng"' showing total 29 results
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29 results on '"Yuan, Xiaomeng"'

6. Cerebellar Mutism Syndrome and Dentato-Thalamo-Cortical Tract Disruption in Diffusion Tractography Following Surgery for Medulloblastoma

Author

Ji, Qing, primary, McAfee, Samuel S., additional, Scoggins, Matthew, additional, Holtrop, Joseph, additional, Glass, John O., additional, Yuan, Xiaomeng, additional, Liang, Jia, additional, Li, Yimei, additional, Chiang, Jason, additional, Orr, Brent A., additional, Edwards, Angela, additional, Storment, Diana, additional, Brinkman, Tara, additional, Robinson, Giles W., additional, Gajjar, Amar, additional, Reddick, Wilburn E., additional, Patay, Zoltán, additional, Khan, Raja B., additional, and Bag, Asim K., additional

Published
2024
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13. Matrix Metalloproteinase-2-Induced Morphologic Transformation of Self-Assembled Peptide Nanocarriers Inhibits Tumor Growth and Metastasis

Author

Cao, Juanjuan, primary, Yuan, Xiaomeng, additional, Sun, Xinyu, additional, Meng, Fanhu, additional, Li, Hongjie, additional, Hong, Zexin, additional, Liu, Yun, additional, Zhai, Xiaoqing, additional, Ma, Jihong, additional, Peng, Shan, additional, Zhou, Yuqi, additional, Liu, Xiaoying, additional, Hao, Jingcheng, additional, and Bai, Jingkun, additional

Published
2023
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16. Working memory and school readiness in preschool children with sickle cell disease compared to demographically matched controls

Author

Heitzer, Andrew M., primary, Schreiber, Jane E., additional, Yuan, Xiaomeng, additional, Wang, Fang, additional, Pan, Haitao, additional, Graff, J. Carolyn, additional, Murphy, Laura, additional, Rupff, Rebecca, additional, Russell, Kathryn, additional, Wang, Winfred, additional, Estepp, Jeremie H., additional, Hankins, Jane S., additional, Porter, Jerlym S., additional, and Jacola, Lisa M., additional

Published
2022
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20. Dark Triad and Emotional Manipulation

Author

Yuan, Xiaomeng

Subjects
dark triad, gaslighting, emotional manipulation, emotional intelligence, attachment
Abstract

From the perspective of social issues, this study explores the concepts and theories related to emotional intelligence, Machiavellianism, psychopathy, narcissism, emotional manipulation and gaslighting. This study aims to reveal the general features of emotional manipulation and shared personality traits, in hopes to further understand the power and control in intimate relationships.

Published
2022
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23. Working memory and school readiness in preschool children with sickle cell disease compared to demographically matched controls.

Author

Heitzer, Andrew M., Schreiber, Jane E., Yuan, Xiaomeng, Wang, Fang, Pan, Haitao, Graff, J. Carolyn, Murphy, Laura, Rupff, Rebecca, Russell, Kathryn, Wang, Winfred, Estepp, Jeremie H., Hankins, Jane S., Porter, Jerlym S., and Jacola, Lisa M.

Subjects
READINESS for school, SICKLE cell anemia, SHORT-term memory, PRESCHOOL children, PARENTING education, PRESCHOOL teachers, DYSFUNCTIONAL families
Abstract

Summary: Children diagnosed with sickle cell disease (SCD) are at risk of the development of neurobehavioural problems early in life. Specific impairments in executive function skills, including working memory, have been documented in school‐aged children with SCD. These executive skills are known to strongly contribute to early academic skills and preparedness for entering kindergarten. This study examined working memory and school readiness in preschool children with SCD compared to a healthy control group matched for race, sex and parent education. A total of 84 patients diagnosed with SCD (61.9% haemoglobin [Hb]SS/HbSβ0‐thalassaemia) and 168 controls completed testing. The mean (SD) ages of patients and controls at testing were 4.53 (0.38) and 4.44 (0.65) years respectively. The SCD group performed worse than controls on measures of executive function, working memory and school readiness (p < 0.01; Cohen's D range: 0.32–0.39). Measures of working memory were associated with school readiness after accounting for early adaptive development. Multiple linear regression models among patients diagnosed with SCD revealed that college education of the primary caregiver was positively associated with school readiness (p < 0.001) after controlling for sex, genotype, age and early adaptive development. These results highlight the need to implement school readiness interventions in young children diagnosed with SCD emphasising executive function skills. [ABSTRACT FROM AUTHOR]

Published
2023
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27. pH‐Triggered Transformable Peptide Nanocarriers Extend Drug Retention for Breast Cancer Combination Therapy

Author

Yuan, Xiaomeng, Liu, Xiaoying, Li, Hongjie, Peng, Shan, Huang, Haiqin, Yu, Zhe, Chen, Limei, Liu, Xinlu, and Bai, Jingkun

Abstract

Increasing the penetration and accumulation of antitumor drugs at the tumor site are crucial in chemotherapy. Smaller drug‐loaded nanoparticles (NPs) typically exhibit increased tumor penetration and more effective permeation through the nuclear membrane, whereas larger drug‐loaded NPs show extended retention at the tumor site. In addition, cancer stem cells (CSCs) have unlimited proliferative potential and are crucial for the onset, progression, and metastasis of cancer. Therefore, a drug‐loaded amphiphilic peptide, DDP‐ and ATRA‐loaded Pep1 (DA/Pep1), is designed that self‐assembles into spherical NPs upon the encapsulation of cis‐diamminedichloroplatinum (DDP) and all‐transretinoic acid (ATRA). In an acidic environment, DA/Pep1 transforms into aggregates containing sheet‐like structures, which significantly increases drug accumulation at the tumor site, thereby increasing antitumor effects and inhibiting metastasis. Moreover, although DDP treatment can increase the number of CSCs present, ATRA can induce the differentiation of CSCs in breast cancer to increase the therapeutic effect of DDP. In conclusion, this peptide nanodelivery system that transforms in response to the acidic tumor microenvironment is an extremely promising nanoplatform that suggests a new idea for the combined treatment of tumors. After the encapsulation of cis‐diamminedichloroplatinum and all‐transretinoic acid, an amphiphilic peptide self‐assembles to form spherical nanoparticles, which target acidic fibroblast growth factor and form sheet‐like aggregates in the slightly acidic environment. This transformation increases drug accumulation at the tumor site and prolongs drug retention, thereby increasing antitumor efficacy and the inhibition of lung metastasis.

Published
2024
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