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Your search keyword '"van Delft, Joost"' showing total 17 results
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17 results on '"van Delft, Joost"'

1. Supplementary Table 1 from Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure In Utero

Author

Hochstenbach, Kevin, primary, van Leeuwen, Danitsja M., primary, Gmuender, Hans, primary, Gottschalk, Ralf W., primary, Løvik, Martinus, primary, Granum, Berit, primary, Nygaard, Unni, primary, Namork, Ellen, primary, Kirsch-Volders, Micheline, primary, Decordier, Ilse, primary, Vande Loock, Kim, primary, Besselink, Harrie, primary, Törnqvist, Margareta, primary, von Stedingk, Hans, primary, Rydberg, Per, primary, Kleinjans, Jos C.S., primary, van Loveren, Henk, primary, and van Delft, Joost H.M., primary

Published
2023
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2. Supplementary Table 2 from Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure In Utero

Author

Hochstenbach, Kevin, primary, van Leeuwen, Danitsja M., primary, Gmuender, Hans, primary, Gottschalk, Ralf W., primary, Løvik, Martinus, primary, Granum, Berit, primary, Nygaard, Unni, primary, Namork, Ellen, primary, Kirsch-Volders, Micheline, primary, Decordier, Ilse, primary, Vande Loock, Kim, primary, Besselink, Harrie, primary, Törnqvist, Margareta, primary, von Stedingk, Hans, primary, Rydberg, Per, primary, Kleinjans, Jos C.S., primary, van Loveren, Henk, primary, and van Delft, Joost H.M., primary

Published
2023
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3. Data from Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure In Utero

Author

Hochstenbach, Kevin, primary, van Leeuwen, Danitsja M., primary, Gmuender, Hans, primary, Gottschalk, Ralf W., primary, Løvik, Martinus, primary, Granum, Berit, primary, Nygaard, Unni, primary, Namork, Ellen, primary, Kirsch-Volders, Micheline, primary, Decordier, Ilse, primary, Vande Loock, Kim, primary, Besselink, Harrie, primary, Törnqvist, Margareta, primary, von Stedingk, Hans, primary, Rydberg, Per, primary, Kleinjans, Jos C.S., primary, van Loveren, Henk, primary, and van Delft, Joost H.M., primary

Published
2023
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4. Supplementary Table 3 from Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure In Utero

Author

Hochstenbach, Kevin, primary, van Leeuwen, Danitsja M., primary, Gmuender, Hans, primary, Gottschalk, Ralf W., primary, Løvik, Martinus, primary, Granum, Berit, primary, Nygaard, Unni, primary, Namork, Ellen, primary, Kirsch-Volders, Micheline, primary, Decordier, Ilse, primary, Vande Loock, Kim, primary, Besselink, Harrie, primary, Törnqvist, Margareta, primary, von Stedingk, Hans, primary, Rydberg, Per, primary, Kleinjans, Jos C.S., primary, van Loveren, Henk, primary, and van Delft, Joost H.M., primary

Published
2023
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5. Supplementary Table 4 from Global Gene Expression Analysis in Cord Blood Reveals Gender-Specific Differences in Response to Carcinogenic Exposure In Utero

Author

Hochstenbach, Kevin, primary, van Leeuwen, Danitsja M., primary, Gmuender, Hans, primary, Gottschalk, Ralf W., primary, Løvik, Martinus, primary, Granum, Berit, primary, Nygaard, Unni, primary, Namork, Ellen, primary, Kirsch-Volders, Micheline, primary, Decordier, Ilse, primary, Vande Loock, Kim, primary, Besselink, Harrie, primary, Törnqvist, Margareta, primary, von Stedingk, Hans, primary, Rydberg, Per, primary, Kleinjans, Jos C.S., primary, van Loveren, Henk, primary, and van Delft, Joost H.M., primary

Published
2023
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16. The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

Author

Wang, Charles, primary, Gong, Binsheng, additional, Bushel, Pierre R, additional, Thierry-Mieg, Jean, additional, Thierry-Mieg, Danielle, additional, Xu, Joshua, additional, Fang, Hong, additional, Hong, Huixiao, additional, Shen, Jie, additional, Su, Zhenqiang, additional, Meehan, Joe, additional, Li, Xiaojin, additional, Yang, Lu, additional, Li, Haiqing, additional, Łabaj, Paweł P, additional, Kreil, David P, additional, Megherbi, Dalila, additional, Gaj, Stan, additional, Caiment, Florian, additional, van Delft, Joost, additional, Kleinjans, Jos, additional, Scherer, Andreas, additional, Devanarayan, Viswanath, additional, Wang, Jian, additional, Yang, Yong, additional, Qian, Hui-Rong, additional, Lancashire, Lee J, additional, Bessarabova, Marina, additional, Nikolsky, Yuri, additional, Furlanello, Cesare, additional, Chierici, Marco, additional, Albanese, Davide, additional, Jurman, Giuseppe, additional, Riccadonna, Samantha, additional, Filosi, Michele, additional, Visintainer, Roberto, additional, Zhang, Ke K, additional, Li, Jianying, additional, Hsieh, Jui-Hua, additional, Svoboda, Daniel L, additional, Fuscoe, James C, additional, Deng, Youping, additional, Shi, Leming, additional, Paules, Richard S, additional, Auerbach, Scott S, additional, and Tong, Weida, additional

Published
2014
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17. Transcriptomic alterations induced by Monuron in rat and human renal proximal tubule cells in vitroand comparison to rat renal-cortex in vivo

Author

Bloch, Katarzyna M., Yaqoob, Noreen, Sharma, Sikander, Evans, Andrew, Aschauer, Lydia, Radford, Robert, Jennings, Paul, Ryan, Michael P., van Delft, Joost H. M., and Lock, Edward A.

Abstract

Monuron (1,1-dimethyl-3-(4-chlorophenyl)urea) is a non-selective phenylurea herbicide, widely used in developing countries although concerns have been raised about its toxicity and carcinogenicity. Monuron was evaluated by the National Toxicology Program in 1988 and shown to be a male rat-specific renal carcinogen. We report that oral administration of Monuron to male rats for 3 days, leads to a larger number of genes being differentially expressed in the renal-cortex than in the liver. Further, we observed up-regulation of cell cycle genes and genes involved in cell proliferation in the renal-cortex while in the liver xenobiotic metabolising enzymes were up-regulated. We also identified one commonly down-regulated gene in both organs – fragile histidine triad gene (Fhit), a putative tumour suppressor gene; however the down-regulation was only significant at the protein level in the liver. In addition, we conducted in vitrowhole-genome transcriptomics studies with human and rat renal cortical cells. Rat cells exposed to Monuron showed down-regulation of sterol biosynthesis, spliceosome and cell cycle genes and up-regulation of genes involved in amino acid metabolism and transport. No genes were found to be differentially expressed in human cells exposed to Monuron. Overall, the findings from the in vitrostudies showed very little overlap with the whole animal findings.

Published
2015
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