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Mountain glaciers are one of the most sensitive indicators of climate change. Reconstructing past glacier extents provides valuable insights into the climate change for specific regions where instrumental records are not enough and even absent. In the paper we mapped the outlines for 691 Little Ice Age (LIA) glaciers in terms of prominent moraines beyond contemporary glaciers in the Tanggula Mountains, central Tibetan Plateau (TP). Based on these glacier outlines, we reconstructed the ice thicknesses and surfaces for the LIA glaciers in the region. Accordingly, we calculated the equilibrium-line altitudes (ELAs) for contemporary and LIA glaciers. By comparing the ELAs between the contemporary and LIA glaciers, we estimated the LIA summer temperature decreases in different subregions of the Tanggula Mountains. Since the LIA, the ELA have risen by 35.6 ± 18.8 m, 26.1 ± 17.6 m, and 63.1 ± 38.6 m in the respective western, central, and eastern subregions of the Tanggula Mountains. Assuming no change in precipitation, the LIA summer temperature would decrease by 0.22 ± 0.12 °C, 0.14 ± 0.09 °C, and 0.34 ± 0.21 °C in the three subregions, respectively. Moreover, glaciers in the western, central, and eastern subregions have lost 13.3%, 23.9%, and 42.8% of their area, 15.4%, 25.3%, and 39.6% of their length, and 20.8%, 39.0%, and 61.0% of their volume, respectively. By compiling the LIA ELA data from previous studies, we also estimated the LIA summer temperature changes for other regions of the TP. The LIA ELA and summer temperature changes relative to the present showed a decreasing trend from the edges towards the interior on the TP. • LIA glaciers and summer climate were reconstructed at the Tanggula Mountains. • LIA summers were 0.22 ± 0.12 °C, 0.14 ± 0.09 °C, and 0.34 ± 0.21 °C cooler than present in three subregions. • Summer temperature change had a decreasing trend from the edges towards the interior on the Tibetan Plateau. [ABSTRACT FROM AUTHOR]