Search

Your search keyword '"Zhou, Qiang"' showing total 26 results
Start Over Author "Zhou, Qiang" Search Limiters Peer Reviewed Publication Year Range Last 3 years Publisher hindawi limited
26 results on '"Zhou, Qiang"'

2. Association of LAMA1 Single-Nucleotide Polymorphisms with Risk of Esophageal Squamous Cell Carcinoma among the Eastern Chinese Population

Author

Zhang, Shaoyuan, primary, Fang, Yong, additional, Su, Feng, additional, Jiang, Tian, additional, Yu, Jinjie, additional, Lin, Siyun, additional, Lv, Lu, additional, Long, Tao, additional, Pan, Huiwen, additional, Qi, Junqing, additional, Zhou, Qiang, additional, Tang, Weifeng, additional, Ding, Guowen, additional, Wang, Liming, additional, Tan, Lijie, additional, and Yin, Jun, additional

Published
2023
Full Text
View/download PDF

4. Identification of Diagnostic Markers in Infantile Hemangiomas

Author

Huang, Sicong, primary, Chen, Ruiqi, additional, Gao, Shihua, additional, Shi, Yongjie, additional, Xiao, Qiwen, additional, Zhou, Qiang, additional, Wei, Jie, additional, Kang, Jiale, additional, Sun, Weimin, additional, Hu, Yingyu, additional, Shen, Gang, additional, and Jia, Hongyun, additional

Published
2022
Full Text
View/download PDF

25. Efficacy of -3 Polyunsaturated Fatty Acids in Patients with Lung Cancer Undergoing Radiotherapy and Chemotherapy: A Meta-Analysis.

Author

Tao, Xin, Zhou, Qiang, and Rao, Zhiyong

Subjects
THERAPEUTIC use of omega-3 fatty acids, META-analysis, INFLAMMATION, LUNG tumors, MALNUTRITION
Abstract

Background: Radiotherapy and chemotherapy in patients with lung cancer can lead to a series of problems such as malnutrition and inflammatory reaction. Some studies have shown that ω-3 polyunsaturated fatty acids (PUFAs) could improve malnutrition and regulate inflammatory reaction in these patients, but no relevant meta-analysis exists.Methods: We systematically searched randomized controlled trials of ω-3 PUFAs in the adjuvant treatment of lung cancer in the PubMed, EMBASE, Cochrane Library, Web of Science, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), and Wanfang databases. Relevant outcomes were extracted, and we pooled standardized mean differences (SMDs) using a random or fixed-effects model. The risk of bias was evaluated according to the Cochrane Handbook (version 15.1). The quality of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).Results: A total of 7 studies were included. The SMDs (95% CI) of body weight change, albumin change, energy intake, and protein intake at the end of intervention were 1.15 (0.50, 1.80), 0.60 (0.11, 1.09), 0.39 (-0.10, 0.89), and 0.27 (-0.04, 0.58), respectively. The SMDs (95% CI) of CRP change and TNF-α change were -3.44 (-6.15, -0.73) and -1.63 (-2.53, -0.73), respectively.Conclusions: ω-3 PUFAs can improve nutritional status and regulate indicators of inflammation in patients with lung cancer undergoing radiotherapy and chemotherapy. This study was registered in the PROSPERO (registration number: CRD42022307699). [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

26. Hypoxia Promotes Glioma Stem Cell Proliferation by Enhancing the 14-3-3 Expression via the PI3K Pathway.

Author

Cao, Weidong, Zhou, Qiang, Wang, Hongwei, Rao, Wei, Cheng, Gang, Wang, Peng, Guo, Shengli, Ren, Bin, and Zhang, Jianning

Subjects
*CELL proliferation, *PROLIFERATING cell nuclear antigen, *GLIOMAS, *STEM cells, *WESTERN immunoblotting
Abstract

Glioma is a serious fatal type of cancer with the shorter median survival period and poor quality of living. The overall 5-year survival rate remains low due to high recurrence rates. Glioma stem cells (GSCs) play the important roles in the development of gliomas. Examination of the numerous biomarkers or cancer-associated genes involved in the development or prevention of glioma may therefore serve the discovery of novel strategies to treat patients with glioma. Hypoxia induced by using CoCl2 application and 14-3-3β protein knockdown by specific small interfering RNA transfection were performed in GSCs both in vitro and in vivo to observe their role in glioma progression and metastasis occurrence by using western blot analysis and MTT assay. The results demonstrated that CoCl2 application enhanced the 14-3-3β protein expression and mRNA levels via the PI3K pathway in GSCs. Furthermore, hypoxia promoted GSC cell proliferation and activated the expression of proliferating cell nuclear antigen, which was inhibited following 14-3-3β knockdown. In addition, tumor growth in mice was enhanced by CoCl2 application but reversed following 14-3-3β knockdown, which also enhanced GSC cell apoptosis. In conclusion, the present study demonstrated that hypoxia promoted glioma growth both in vitro and in vivo by increasing the 14-3-3β expression via the PI3K signaling pathway. 14-3-3β and HIF-1α may therefore be considered as the potential therapeutic target to treat patients with glioma. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results