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In order to explore the causal relationship between the level of urban digital construction and urban economic growth, this paper takes 280 cities in China as the research object and constructs a comprehensive indicator evaluation system covering digital infrastructure, overall economic level, innovation development level, digital industry development status, and ecological environment conditions. Using the entropy method to weigh various indicators, this paper has obtained the evaluation results of the digital construction level of each city from 2011 to 2021. Furthermore, a panel data regression model is used to empirically analyze the impact of urban digital construction level on urban economic growth. The results show that for every 1% increase in the level of urban digital construction, the GDP will increase by 0.974. Through the above research, we hope to further enrich the theoretical and empirical research in the field of the digital economy, provide a scientific and reasonable method for quantitatively evaluating the level of urban digital construction, and provide decision-making references for improving the level of urban digital construction and promoting sustainable urban development. [ABSTRACT FROM AUTHOR]

Rare Earth Elements (REE) phosphates (monazite, xenotime, and rhabdophane) are critical REE-bearing minerals typically formed in hydrothermal and magmatic ore deposits. The thermodynamic properties of those REE minerals are crucial to understanding the solubility, speciation, and transport of REE complexes. However, the standard-state Gibbs free energy of formation (∆G°f) values reported for these minerals in the literature vary by up to 25 kJ mol−1. Here, we present linear free energy relationships that allow the evaluation and estimation of the ∆G°f values at 25 °C and 1 bar for the three minerals from the ionic radius (rREE3+) and the non-solvation Gibbs free energy contribution to the REE3+ aqua ion (∆G°n, REE3+): ∆G°f,monazite − 399.71 rREE3+ = 1.0059 ∆G°n,REE3+ − 2522.51; ∆G°f,xenotime − 344.08 rREE3+ = 0.9909 ∆G°n,REE3+ − 2451.53; and ∆G°f,rhabdophane − 416.17 rREE3+ = 1.0067 ∆G°n, REE3+ − 2688.86. Moreover, based on the new dataset derived for REE end-members, we re-fitted the binary Margules parameter (W) from previous theoretical calculations into linear correlations: W + 0.00204 ∆G°'n,monazite = 39.3549 ∆V + 0.0641; W + 0.00255 ∆G°'n,xenotime = 25.4885 ∆V − 0.0062. The internally consistent thermodynamic properties of these REE phosphates are incorporated into the computer program Supcrtbl, which is available online at Zhu's research website. [ABSTRACT FROM AUTHOR]

The growing demand from the extended reality and wearable electronics market has led to an increased focus on the development of flexible human-machine interfaces (HMI). These interfaces require efficient user input acquisition modules that can realize touch operation, handwriting input, and motion sensing functions. In this paper, we present a systematic review of triboelectric-based contact localization electronics (TCLE) which play a crucial role in enabling the lightweight and long-endurance designs of flexible HMI. We begin by summarizing the mainstream working principles utilized in the design of TCLE, highlighting their respective strengths and weaknesses. Additionally, we discuss the implementation methods of TCLE in realizing advanced functions such as sliding motion detection, handwriting trajectory detection, and artificial intelligence-based user recognition. Furthermore, we review recent works on the applications of TCLE in HMI devices, which provide valuable insights for guiding the design of application scene-specified TCLE devices. Overall, this review aims to contribute to the advancement and understanding of TCLE, facilitating the development of next-generation HMI for various applications. [ABSTRACT FROM AUTHOR]

Fujian province, an important tea-producing area in China, has abundant tea cultivars. To investigate the genetic relationships of tea plant cultivars in Fujian province and the characteristics of the tea plant varieties, a total of 70 tea cultivars from Fujian and other 12 provinces in China were subjected to restriction site-associated DNA sequencing (RAD-seq). A total of 60,258,975 single nucleotide polymorphism (SNP) sites were obtained. These 70 tea plant cultivars were divided into three groups based on analyzing the phylogenetic tree, principal component, and population structure. Selection pressure analysis indicated that nucleotide diversity was high in Southern China and genetically distinct from cultivars of Fujian tea plant cultivars, according to selection pressure analysis. The selected genes have significant enrichment in pathways associated with metabolism, photosynthesis, and respiration. There were ten characteristic volatiles screened by gas chromatography–mass spectrometry (GC–MS) coupled with multivariate statistical methods, among which the differences in the contents of methyl salicylate, 3-carene, cis-3-hexen-1-ol, (E)-4-hexen-1-ol, and 3-methylbutyraldehyde can be used as reference indicators of the geographical distribution of tea plants. Furthermore, a metabolome genome-wide association study (mGWAS) revealed that 438 candidate genes were related to the aroma metabolic pathway. Further analysis showed that 31 genes of all the selected genes were screened and revealed the reasons for the genetic differences in aroma among tea plant cultivars in Fujian and Southern China. These results reveal the genetic diversity in the Fujian tea plants as well as a theoretical basis for the conservation, development, and utilization of the Fujian highly aromatic tea plant cultivars. [ABSTRACT FROM AUTHOR]

The extended finite element method (XFEM) was employed for the computational modeling of internal defects within a bond layer. Furthermore, a cohesive zone model (CZM) was implemented to characterize the behavior of the bond layer in response to interactions at both the bond layer/steel plate and bond layer/asphalt paving layer interfaces. The coupling of XFEM and CZM was used for a comprehensive analysis of crack propagation within the bond layer as well as the assessment of phenomena associated with interfacial debonding and delamination. The feasibility and accuracy of the XFEM–CZM coupling method were verified by comparing it with the virtual crack closure technique (VCCT), CZM, XFEM–VCCT, and experiments. A double cantilever beam experimental model was established to simulate the process of interlayer-type cracks expanding from the inside of the bond layer to the interface between the bond layer and the upper and lower layers, causing debonding. This was undertaken to analyze the damage failure mechanism of interlayer-type cracks in asphalt paving layers of steel bridge decks; to discuss the impacts of the initial crack length, the interface stiffness, the interface strength, and the thickness of the bond layer on the performance of the overall interlayer bond strength; and to carry out the significance analysis. The results showed that the initial crack length, interface stiffness, and bond layer thickness had different effects on the expansion path of interlayer cracks. The interlayer strength decreased with an increase in the initial crack length and interface stiffness, increased with an increase in the interface strength, and decreased with an increase in the thickness of the bond layer. The interface stiffness had the most significant effect on the strength. [ABSTRACT FROM AUTHOR]

This paper describes a concept for local GNSS (Global Navigation Satellite System) augmentation derived from the established Ground Based Augmentation System (GBAS) in civil aviation. The aim of this concept is to provide reliable and accurate GNSS measurements for integration into a redundant, safe and reliable integrated navigation architecture tailored to serve Urban Air Mobility (UAM). The proposed concept for local GNSS augmentation addresses the specific challenges of UAM, in particular for take-off and landing operations, and ensures safe separation between UAM vehicles en route between vertiports. By using less expensive hardware compared to the traditional GBAS, the concept aims to make the integration into future urban airspace easier and more cost-effective, both in terms of ground infrastructure demands and on-board navigation hardware. In addition to the high-level system concept and considerations, we present an initial nominal performance assessment of local augmentation using lower-cost airborne and ground hardware. This assessment is based on actual UAV (Unmanned Aerial Vehicle) flight trials conducted in different urban scenarios, as well as long-term rooftop measurements. [ABSTRACT FROM AUTHOR]

This paper reports a fiber in-line Fabry–Perot interferometer (FPI) fabricated in a no-core fiber using the direct femtosecond laser writing technique for high-temperature sensing applications. Two in-line reflectors are directly inscribed in a no-core fiber to construct a low-finesse FPI. Fringe visibility greater than 10 dB is obtained from the reflection spectra of the fabricated no-core fiber FPIs. Temperature responses of a prototype no-core fiber FPI are characterized up to 1000 °C. The proposed configuration is compact and easy to fabricate, making it attractive for sensing applications in high-temperature harsh environments. [ABSTRACT FROM AUTHOR]

Fruit fly larvae, which exist widely in nature, achieve peristaltic motion via the contraction and elongation of their bodies and the asymmetric friction generated by the front and rear parts of their bodies when they are in contact with the ground. Herein, we report the development of an untethered, magnetic, temperature-sensitive hydrogel-based soft robot that mimics the asymmetric micro-patterns of fruit-fly-larvae gastropods and utilizes cyclic deformation to achieve directional peristaltic locomotion. Due to Néel relaxation losses of nanomagnetic Fe3O4 particles, the hydrogel-based soft robot is capable of converting changes in external alternating magnetic stimuli into contracting and expanding deformation responses which can be remotely controlled via a high-frequency alternating magnetic field (AMF) to realize periodic actuation. Furthermore, the Fe3O4 particles included in the hydrogel-based soft robot cause it to follow a gradient magnetic field in confined liquid environments and can be coupled with AMFs for the targeted release of water-soluble drugs or targeted magnetic hyperthermia therapy (MHT). We believe that such a controlled motion can enable highly targeted drug delivery, as well as vascular disease detection and thrombus removal tasks, without the use of invasive procedures. [ABSTRACT FROM AUTHOR]

Nitrate transporter 2 (NRT2) proteins play vital roles in both nitrate (NO3−) uptake and translocation as well as abiotic stress responses in plants. However, little is known about the NRT2 gene family in Brassica rapa. In this study, 14 NRT2s were identified in the B. rapa genome. The BrNRT2 family members contain the PLN00028 and MATE_like superfamily domains. Cis-element analysis indicated that regulatory elements related to stress responses are abundant in the promoter sequences of BrNRT2 genes. BrNRT2.3 expression was increased after drought stress, and BrNRT2.1 and BrNRT2.8 expression were significantly upregulated after salt stress. Furthermore, protein interaction predictions suggested that homologs of BrNRT2.3, BrNRT2.1, and BrNRT2.8 in Arabidopsis thaliana may interact with the known stress-regulating proteins AtNRT1.1, AtNRT1.5, and AtNRT1.8. In conclusion, we suggest that BrNRT2.1, BrNRT2.3, and BrNRT2.8 have the greatest potential for inducing abiotic stress tolerance. Our findings will aid future studies of the biological functions of BrNRT2 family genes. [ABSTRACT FROM AUTHOR]

The genus Flavivirus is a group of arthropod-borne single-stranded RNA viruses, which includes important human and animal pathogens such as Japanese encephalitis virus (JEV), Zika virus (ZIKV), Dengue virus (DENV), yellow fever virus (YFV), West Nile virus (WNV), and Tick-borne encephalitis virus (TBEV). Reverse genetics has been a useful tool for understanding biological properties and the pathogenesis of flaviviruses. However, the conventional construction of full-length infectious clones for flavivirus is time-consuming and difficult due to the toxicity of the flavivirus genome to E. coli. Herein, we applied a simple, rapid, and bacterium-free circular polymerase extension reaction (CPER) method to synthesize recombinant flaviviruses in vertebrate cells as well as insect cells. We started with the de novo synthesis of the JEV vaccine strain SA-14-14-2 in Vero cells using CPER, and then modified the CPER method to recover insect-specific flaviviruses (ISFs) in mosquito C6/36 cells. Chimeric Zika virus (ChinZIKV) based on the Chaoyang virus (CYV) backbone and the Culex flavivirus reporter virus expressing green fluorescent protein (CxFV-GFP) were subsequently rescued in C6/36 cells. CPER is a simple method for the rapid generation of flaviviruses and other potential RNA viruses. A CPER-based recovery system for flaviviruses of different host ranges was established, which would facilitate the development of countermeasures against flavivirus outbreaks in the future. [ABSTRACT FROM AUTHOR]

Optical fiber sensors that have a compact size and the capability for multi-parameter sensing are desired in various applications. This article reports a miniaturized optical fiber Fabry-Perot interferometric sensor with a length of hundreds of µm that is able to simultaneously measure variations of curvature, temperature, and strain. The sensor is easy to fabricate, requiring only the fusion splicing of a short section of the silica capillary tube between two single-mode fibers (SMFs). The combined mechanism of the Fabry-Perot interference occurred in the two interfaces between the capillary and the SMFs, and the antiresonant guidance induced by the capillary tube makes the device capable of realizing multi-parameter sensing. A simplified coefficient matrix approach is developed to decouple the contributions from different parameters. In addition, the capability of the device for multiplexing is investigated, where four such prototypes with different air cavity lengths are multiplexed in a system in parallel. The spectral behavior of an individual device for measuring curvature and strain is reconstructed and investigated, showing reliable responses and little crosstalk between different devices. The proposed device is easy to fabricate, cost-effective, robust, and could find potential applications in the field of structural health monitoring and medical and human–machine interactive sensing. [ABSTRACT FROM AUTHOR]

Obesity is a leading contributor to colorectal cancer (CRC) risk, but the metabolic mechanisms linking obesity to CRC are not fully understood. We leveraged untargeted metabolomics data from two 1:1 matched, nested case–control studies for CRC, including 223 pairs from the US Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial and 190 pairs from a prospective Chinese cohort. We explored serum metabolites related to body mass index (BMI), constructed a metabolomic signature of obesity, and examined the association between the signature and CRC risk. In total, 72 of 278 named metabolites were correlated with BMI after multiple testing corrections (p FDR < 0.05). The metabolomic signature was calculated by including 39 metabolites that were independently associated with BMI. There was a linear positive association between the signature and CRC risk in both cohorts (p for linear < 0.05). Per 1-SD increment of the signature was associated with 38% (95% CI: 9–75%) and 28% (95% CI: 2–62%) higher risks of CRC in the US and Chinese cohorts, respectively. In conclusion, we identified a metabolomic signature for obesity and demonstrated the association between the signature and CRC risk. The findings offer new insights into the underlying mechanisms of CRC, which is critical for improved CRC prevention. [ABSTRACT FROM AUTHOR]

China's large-scale construction has led to massive energy consumption and carbon emissions. The embodied carbon emissions (ECs) of China's building sector play a key role in realizing national emission reduction targets. Currently, the understanding of the status quo of ECs is vague and inconsistent, and the existing accounting models still have several limitations. Therefore, this study develops two improved models (i.e., the process-based and the input-output-based life cycle assessment models) and dynamic accounting datasets to reveal historical trends and emission characteristics of ECs from 2005 to 2020. The results show that the total ECs in 2020 were as high as 2.28 billion tCO2, accounting for 25.2% of China's total energy-related carbon emissions. The indirect ECs are the largest contributor, representing 95.9% of the total building ECs. The ECs increased quickly at first and entered a plateau, stable at about 2.2 billion tCO2 after 2015. From 2005 to 2020, the total building ECs contributed 38.7% to the national carbon emission growth, while the intensity of ECs showed a downward trend, indicating that the increase in China's building ECs is scale-driven. This study provides sound methodological, and data support for emission tracing and the low-carbon development of China's building sector. [ABSTRACT FROM AUTHOR]

A series of shaking table tests was carried out on the dynamic performance and working mechanism of a gabion reinforced soil retaining wall under seismic load. The test results show that the panel presents the deformation mode of middle and upper bulging at the contact point between the rigid box and the retaining wall The settlement of top backfill is relatively uniform, and there is basically no differential settlement, the natural frequencies at different positions and heights inside the retaining wall are basically the same, and the natural frequencies are stable between 22.61 and 23.04 Hz below 0.8 g. The damping ratio decreases with the increase in wall height, and the damping ratio at each stage after vibration is greater than that before vibration. The seismic earth pressure is nonlinearly distributed. The measured value of the lower part of the retaining wall is smaller than that calculated by the Seed–Whitman method with an increase in peak acceleration, and the measured value of the upper part of the retaining wall is larger than the theoretical calculation results. The position of the resultant action point of seismic earth pressure is greater than 0.33 times the wall height specified by the Mononobe–Okabe method. [ABSTRACT FROM AUTHOR]

The attention on orthopedic biomaterials has shifted from their direct osteogenic properties to their osteoimmunomodulation, especially the modulation of macrophage polarization. Presently, advanced technologies endow polyetheretherketone (PEEK) with good osteoimmunomodulation by modifying PEEK surface characteristics or incorporating bioactive substances with regulating macrophage polarization. Recent studies have demonstrated that the fabrication of a hydrophilic surface and the incorporation of bioactive substances into PEEK (e.g., zinc, calcium, and phosphate) are good strategies to promote osteogenesis by enhancing the polarization of M2 macrophages. Furthermore, the modification by other osteoimmunomodulatory composites (e.g., lncRNA-MM2P, IL-4, IL-10, and chitosan) and their controlled and desired release may make PEEK an optimal bio-activated implant for regulating and balancing the osteogenic system and immune system. The purpose of this review is to comprehensively evaluate the potential of bio-activated PEEK in polarizing macrophages into M2 phenotype to improve osteogenesis. For this objective, we retrieved and discussed different kinds of bio-activated PEEK regarding improving osteogenesis through modulating macrophage polarization. Meanwhile, the relevant challenges and outlook were presented. We hope that this review can shed light on the development of bio-activated PEEK with more favorable osteoimmunomodulation. [ABSTRACT FROM AUTHOR]

The flavour of white tea can be influenced by the season in which the fresh leaves are picked. In this study, the sensory evaluation results indicated that spring-picked white tea (SPWT) was stronger than autumn-picked white tea (APWT) in terms of the taste of umami, smoothness, astringency, and thickness as well as the aromas of flower and fresh. To explore key factors of sensory differences, a combination of biochemical composition determination, widely targeted volatilomics (WTV) analysis, multivariate statistical analysis, and odour activity value (OAV) analysis was employed. The phytochemical analysis showed that the free amino acid, tea polyphenol, and caffeine contents of SPWTs were significantly higher than those of APWTs, which may explain the higher umami, smoothness, thickness, and astringency scores of SPWTs than those of APWTs. The sabinene, (2E, 4E)-2, 4-octadienal, (-)-cis-rose oxide, caramel furanone, trans-rose oxide, and rose oxide contents were significantly higher in SPWTs than in APWTs, which may result in stronger flowery, fresh, and sweet aromas in SPWTs than in APWTs. Among these, (2E,4E)-2,4-octadienal and (-)-cis-rose oxide can be identified as key volatiles. This study provides an objective and accurate basis for classifying SPWTs and APWTs at the metabolite level. [ABSTRACT FROM AUTHOR]

The present study aimed to explore the effects of ultra-high pressure (UHP) on the cathepsin (B, D, H, and L) activities, protein oxidation, and degradation properties as well as quality characteristics of iced shrimp (Litopenaeus vannamei). Fresh shrimps were vacuum-packed, treated with UHP (100–500 MPa for 5 min), and stored at 0 °C for 15 days. The results showed that the L* (luminance), b* (yellowness), W (whiteness), ΔE (color difference), hardness, shear force, gumminess, chewiness, and resilience of shrimp were significantly improved by UHP treatment. Moreover, the contents of surface hydrophobicity, myofibril fragmentation index (MFI), trichloroacetic acid (TCA)-soluble peptides, carbonyl, dityrosine, and free sulfhydryl of myofibrillar protein (MP) were significantly promoted by UHP treatment. In addition, UHP (above 300 MPa) treatment enhanced the mitochondrial membrane permeability but inhibited the lysosomal membrane stability, and the cathepsin (B, D, H, and L) activities. UHP treatment notably inhibited the activities of cathepsins, delayed protein oxidation and degradation, as well as texture softening of shrimp during storage. Generally, UHP treatment at 300 MPa for 5 min effectively delayed the protein and quality deterioration caused by endogenous enzymes and prolonged the shelf life of shrimp by 8 days. [ABSTRACT FROM AUTHOR]

Alcohol consumption has been associated with the risk of mild cognitive impairment (MCI) in observational studies. The result is inconsistent and whether the association is causal remains unknown. To examine the causal effect of alcohol consumption on MCI in rural China, this study used a cross-sectional dataset that included 1966 observations collected in rural China, of which 235 observations' genotyping were collected. All participants accepted the MCI evaluation using Mini-Cog and were asked about the participants' alcohol consumption behavior. The causal effect of alcohol consumption on MCI was investigated by Mendelian randomization (MR) of genetic variation in the aldehyde dehydrogenase 2 (ALDH2 rs671) gene. The risk of MCI in Chinese rural areas was 43%. Alcohol consumption was causally associated with a higher risk of MCI under MR design. Parameter estimates of drinking or not (b = 0.271, p = 0.007, 95% CI = 0.073 to 0.469), drinking frequency during the past 30 days (b = 0.016, p = 0.003, 95% CI = 0.005 to 0.027), and the weekly ethanol consumption (b = 0.132, p = 0.004, 95% CI = 0.042 to 0.223) were all positive and statistically significant at the 5% level. In conclusion, there was a high risk of MCI in rural China, and alcohol consumption was causally associated with a higher risk of MCI. [ABSTRACT FROM AUTHOR]

Promoting the transition from animal meat to plant-based food consumption has significant benefits for public health and environmental sustainability. This study, involving 526 consumers from Beijing, China, explores how food attributes and information may affect consumers' food choices concerning plant-based meat products. A discrete choice experiment was conducted using burgers with five attributes (meat patties, flavor, sodium content, energy, and price) as the focal product. Separate messages on nutrition, food safety, and the environmental issues related to plant-based meat consumption were also randomly provided to consumers to help examine the role of information. Our findings suggest that Beijing consumers' awareness of plant-based meat is relatively low at present, and they show a negative preference toward plant-based meat consumption relative to that of conventional meat. However, consumers' willingness to pay for plant-based meat significantly increased after nutrition information was provided, but it was not responsive to the provision of food safety or environmental information. These findings suggest that to promote plant-based meat consumption, information closely related to consumers' personal interests rather the "greater good" should be provided, at least in the context of Beijing, China. [ABSTRACT FROM AUTHOR]

Rougui Wuyi Rock tea (WRT) with special flavor can be affected by multiple factors that are closely related to the culturing regions of tea plants. The present research adopted non-targeted metabolomics based on liquid chromatography–mass spectrometry (LC-MS) and gas chromatography–mass spectrometry (GC-MS), aroma activity value method (OAV), and chemometrics to analyze the characteristic metabolites of three Rougui WRTs from different culturing regions. The results of sensory evaluation showed that the three Rougui Wuyi Rock teas had significantly different flavor qualities, especially in taste and aroma. Rougui (RG) had a heavy and mellow taste, while cinnamon-like odor Rougui (GPRG) and floral and fruity odor Rougui (HGRG) had a thick, sweet, and fresh taste. The cinnamon-like odor was more obvious and persistent in GPRG than in RG and HGRG. HGRG had floral and fruity characteristics such as clean and lasting, gentle, and heavy, which was more obvious than in RG and GPRG. The results of principal component analysis (PCA) showed that there were significant metabolic differences among the three Rougui WRTs. According to the projection value of variable importance (VIP) of the partial least squares discriminant analysis (PLS–DA), 24 differential non-volatile metabolites were identified. The PLSR analysis results showed that rutin, silibinin, arginine, lysine, dihydrocapsaicin, etc. may be the characteristic non-volatiles that form the different taste outlines of Rougui WRT. A total of 90 volatiles, including aldehydes, alcohols, esters, and hydrocarbons, were identified from the three flavors of Rougui WRT by using GC-MS. Based on OAV values and PLS-DA analysis, a total of 16 characteristic volatiles were identified. The PLSR analysis results showed that 1-penten-3-ol, α-pinene, 2-carene, β-Pinene, dehydrolinalool, adipaldehyde, D-limonene, saffron aldehyde, and 6-methyl-5-hepten-2-one may be the characteristic volatiles that form the different aroma profile of Rougui WRT. These results provide the theoretical basis for understanding the characteristic metabolites that contribute to the distinctive flavors of Rougui WRT. [ABSTRACT FROM AUTHOR]

mtDNA sequences can be incorporated into the nuclear genome and produce nuclear mitochondrial fragments (NUMTs), which resemble mtDNA in their sequence but are transmitted biparentally, like the nuclear genome. NUMTs can be mistaken as real mtDNA and may lead to the erroneous impression that mtDNA is biparentally transmitted. Here, we report a case of mtDNA heteroplasmy in a Drosophila melanogaster DGRP line, in which the one haplotype was biparentally transmitted in an autosomal manner. Given the sequence identity of this haplotype with the mtDNA, the crossing experiments led to uncertainty about whether heteroplasmy was real or an artifact due to a NUMT. More specific experiments revealed that there is a large NUMT insertion in the X chromosome of a specific DGRP line, imitating biparental inheritance of mtDNA. Our result suggests that studies on mtDNA heteroplasmy and on mtDNA inheritance should first exclude the possibility of NUMT interference in their data. [ABSTRACT FROM AUTHOR]

In this article, a new concept of microwave photonic (MWP) fiber ring resonator is introduced. In particular, the complex transmission spectra of the resonator in the microwave domain, including magnitude and phase spectra, are measured and characterized. Multiple resonance peaks are obtained in the magnitude spectrum; rapid variations in phase near resonance (i.e., enhanced group delay) are observed in the phase spectrum. We also experimentally demonstrate that the MWP fiber ring resonator can be potentially employed as a novel optical fiber sensor for macro-bending and fiber length change sensing (strain sensing). The experimental results are in good agreement with theoretical predictions. [ABSTRACT FROM AUTHOR]

Although photovoltaic (PV) systems play an essential role in distributed generation systems, they also suffer from serious safety concerns due to DC series arc faults. This paper proposes a lightweight convolutional neural network-based method for detecting DC series arc fault in PV systems to solve this issue. An experimental platform according to UL1699B is built, and current data ranging from 3 A to 25 A is collected. Moreover, test conditions, including PV inverter startup and irradiance mutation, are also considered to evaluate the robustness of the proposed method. Before fault detection, the current data is preprocessed with power spectrum estimation. The lightweight convolutional neural network has a lower computational burden for its fewer parameters, which can be ready for embedded microprocessor-based edge applications. Compared to similar lightweight convolutional network models such as Efficientnet-B0, B2, and B3, the Efficientnet-B1 model shows the highest accuracy of 96.16% for arc fault detection. Furthermore, an attention mechanism is combined with the Efficientnet-B1 to make the algorithm more focused on arc features, which can help the algorithm reduce unnecessary computation. The test results show that the detection accuracy of the proposed method can be up to 98.81% under all test conditions, which is higher than that of general networks. [ABSTRACT FROM AUTHOR]

Therapeutic enzymes play important roles in modern medicine due to their high affinity and specificity. However, it is very expensive to use them in clinical medicine because of their low stability and bioavailability. To improve the stability and effectiveness of therapeutic enzymes, immobilization techniques have been employed to enhance the applications of therapeutic enzymes in the past few years. Reported immobilization techniques include entrapment, adsorption, and covalent attachment. In addition, protein engineering is often used to improve enzyme properties; however, all methods present certain advantages and limitations. For carrier-bound immobilization, the delivery and release of the immobilized enzyme depend on the properties of the carrier and enzyme. In this review, we summarize the advantages and challenges of the current strategies developed to deliver therapeutic enzymes and provide a future perspective on the immobilization technologies used for therapeutic enzyme delivery. [ABSTRACT FROM AUTHOR]

MicroRNA166 (miR166) is a highly conserved plant miRNA that plays a crucial role in plant growth and the resistance to various abiotic stresses. However, the miR166s in tea (Camellia sinensis (L.) O. Kuntze) have not been comprehensively identified and analyzed. This study identified 30 mature miR166s and twelve pre-miR166s in tea plants. An evolutionary analysis revealed that csn-miR166s originating from the 3′ arm of their precursors were more conserved than the csn-miR166s derived from the 5′ arm of their precursors. The twelve pre-miR166s in tea were divided into two groups, with csn-MIR166 Scaffold364-2 separated from the other precursors. The Mfold-based predictions indicated that the twelve csn-MIR166s formed typical and stable structures comprising a stem-loop hairpin, with minimum free energy ranging from −110.90 to −71.80 kcal/mol. An analysis of the CsMIR166 promoters detected diverse cis-acting elements, including those related to light responses, biosynthesis and metabolism, abiotic stress defenses, and hormone responses. There was no one-to-one relationship between the csn-miR166s and their targets, but most csn-miR166s targeted HD-Zip III genes. Physiological characterization of tea plants under drought stress showed that leaf water content proportionally decreased with the aggravation of drought stress. In contrast, tea leaves' malondialdehyde (MDA) content proportionally increased. Moreover, the cleavage site of the ATHB-15-like transcript was identified according to a modified 5′ RNA ligase-mediated rapid amplification of cDNA ends. The RT-qPCR data indicated that the transcription of nine csn-miR166s was negatively correlated with their target gene. [ABSTRACT FROM AUTHOR]

We used three-dimensional (3D), high-resolution simulations facilitated by parallel computation to assess the effect of hydrogeological heterogeneity in the Mt. Simon Sandstone on CO2 plume evolution and storage and geochemical reactions in a portion of the Illinois Basin, Indiana. Two scenarios were selected to investigate the effects of the hydrogeological heterogeneity in 3D reactive transport simulations: a heterogeneous case with variable porosity and permeability, and a homogenous case with constant porosity and permeability. The initial pressure, temperature, and mineralogical distributions are consistently applied in both the heterogeneous case and the homogeneous case. Results indicate that including hydrogeological heterogeneity in 3D reservoir simulations for geological CO2 storage significantly impacts modeling results for plume migration patterns, CO2-water-mineral interaction, reservoir quality, and CO2 plume containment. In particular, results indicate that (1) the CO2 plume reached the top of the Mt. Simon Sandstone in the homogeneous case, but was restrained to the lower third of the formation when hydrogeologic heterogeneity was considered; (2) the dominant trapping mechanism in the heterogeneous case was mineral trapping (43%), while it was solubility trapping (47%) in the homogeneous case (at 10,000 years); (3) incorporating reservoir heterogeneity in the model leads to a higher likelihood of long-term containment. [ABSTRACT FROM AUTHOR]

Most of the damage to reinforced retaining walls is caused by excessive deformation; however, there is no calculation method for deformation under static and dynamic loads in the design codes of reinforced soil retaining walls. In this paper, by collecting the measured displacement data from four actual projects, four indoor prototype tests and two indoor model tests under a total of 10 static load conditions, and comparing the calculation results with seven theoretical methods, the results show that the FHWA method is more applicable to the permanent displacement prediction of indoor prototype tests and that the CTI method is more applicable to the permanent displacement prediction of actual projects and indoor model tests. Two yield acceleration calculation methods and four permanent displacement calculation formulas were selected to calculate the displacement response of two reinforced soil test models under seismic loads and compared with the measured values, and the results showed that the Ausilio yield acceleration solution method was better. When the input peak acceleration ranges from 0.1 to 0.6 g, the Richards and Elms upper limit method is used, and when the input peak acceleration is 0.6–1.0 g, the Newmark upper limit method can predict the permanent displacement of the retaining wall more accurately. [ABSTRACT FROM AUTHOR]

Solid phase extraction (SPE) is regarded as the most effective purification method for complex matrix samples owing to its simplicity of operator, time-saving, high accuracy, and environmental friendliness. SPE technology is still affected by the high cost of commercial SPE columns and poor adsorption selectivity. Hence, the development of low-cost and highly selective adsorbents is quite challenging and demanding in SPE. In this study, a novel 3DG functionalized magnetic solid phase extraction materials was prepared based on "thiol-ene" click chemistry. The structure, morphology, thermal stability, and magnetic properties of the magnetic composites were studied by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), thermogravimetric analysis (TGA), and vibrating sample magnetometer (VSM). Then the adsorption performance of composite was determined by static adsorption experiments, which showed fast binding kinetics (100 min) and good adsorption performance (Qe= 65.34 mg/g). Moreover, these magnetic nanoparticles were used as adsorbents for magnetic solid phase extraction (MSPE) and coupled with high-performance liquid chromatography (HPLC) for separation and detection of illegally added hexamethylenetetramine in vermicelli. As for practical application, the recoveries for the spiked samples in the concentration range of 8–40 μg/g were between 83.24–92.69%, and the RSD was between 0.20–2.07%. [ABSTRACT FROM AUTHOR]

Ghost imaging is an indirect optical imaging technique, which retrieves object information by calculating the intensity correlation between reference and bucket signals. However, in existing correlation functions, a high number of measurements is required to acquire a satisfied performance, and the increase in measurement number only leads to limited improvement in image quality. Here, inspired by the gradient descent idea that is widely used in artificial intelligence, we propose a gradient-descent-like ghost imaging method to recursively move towards the optimal solution of the preset objective function, which can efficiently reconstruct high-quality images. The feasibility of this technique has been demonstrated in both numerical simulation and optical experiments, where the image quality is greatly improved within finite steps. Since the correlation function in the iterative formula is replaceable, this technique offers more possibilities for image reconstruction of ghost imaging. [ABSTRACT FROM AUTHOR]

Lithium-sulfur (Li-S) batteries have received extensive attention due to their high theoretical specific capacity and theoretical energy density. However, their commercialization is hindered by the shuttle effect caused by the dissolution of lithium polysulfide. To solve this problem, a method is proposed to improve the performance of Li-S batteries using Ti2N(Ti2NS2) with S-functional groups as the sulfur cathode host material. The calculation results show that due to the mutual attraction between Li and S atoms, Ti2NS2 has the moderate adsorption energies for Li2Sx species, which is more advantageous than Ti2NO2 and can effectively inhibit the shuttle effect. Therefore, Ti2NS2 is a potential cathode host material, which is helpful to improve the performance of Li-S batteries. This work provides a reference for the design of high-performance sulfur cathode materials. [ABSTRACT FROM AUTHOR]