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Exploring the complex relationship between population change and surface urban heat island (SUHI) effect has important practical significance for the ecological transformation development of shrinking cities in the context of the prevalence of urban shrinkage and the global climate change. This paper compares the population change and SUHI effect between population shrinking region (Northeast Region, NR) and population growing region (Yangtze River Delta, YRD) in China, and explores their differences in driving mechanisms, using GIS spatial analysis and Geodetector model. Our results indicated that there are significant differences in population changes and SUHI intensity between these two regions. About 72.22% of the cities in the NR were shrinking, while their SUHI intensities increased by an average of 1.69°C. On the contrary, the urban population in the YRD shows a linear growth trend, while their SUHI intensities decreased by 0.11°C on average. The results of bivariate Moran's I index also indicated that the spatial correlation between the urban population changes and the SUHI intensity changes are not significant in the above regions. Furthermore, there are significant differences in the primary drivers of SUHI variations between these two regions. In the NR, underlying surface changes, including the changes of green coverage and built-up areas, are the most important driving factors. However, atmospheric environment changes, such as carbon dioxide emission and sulfur dioxide emission, are the key drivers in the YRD. Northam's theory of three-stage urbanization and environmental Kuznets curve hypothesis are powerful to explain these differences. [ABSTRACT FROM AUTHOR]

Digital technology innovation is the core driving force for the high-quality development of the digital economy, and in-depth exploration of the regional distribution pattern and formation mechanism of digital technology innovation in China is conducive to the rational layout and coordinated development of the inter-provincial digital economy. Based on the Reference Relationship Table of the Classification of Core Industries of Digital Economy and the International Patent Classification (2023), the patent authorization data of digital technology from 2012 to 2022 were obtained, and the spatiotemporal situation of China's digital technology innovation was analyzed by using ArcGIS software, Dagum's Gini coefficient, and Moran's I index, and the spatial Dubin panel model was used to explore the influencing factors of digital technology innovation. It is found that: (1) the scale and vitality of China's digital technology innovation have increased significantly, and there are obvious spatial differentiation characteristics, and the innovation level of "eastern coastal—central and western interior" is decreasing, forming a cluster distribution pattern in the Yangtze River Delta region, Beijing, Guangdong, and other places, and the degree of agglomeration is decreasing. (2) The overall regional differences in China's digital technology innovation are large, the differences between the East and the West dominate the interregional differences, and the net differences between regions are the main factors leading to regional differences. (3) There is a significant positive spatial correlation between the scale and vitality of digital technology innovation, which has a significant spatial spillover effect. (4) The results confirm that the level of economic development, digital access, financial scientific and technological support, technology market development level, and R&D intensity have a significant positive impact on the scale and vitality of digital technology innovation; The investment in scientific and technological talents has a significant positive impact on the scale of digital technology innovation, but has no significant impact on the vitality of digital technology innovation. [ABSTRACT FROM AUTHOR]

Under the new development pattern, the penetration and integration between industries is becoming increasingly active, constantly promoting the rationalisation and heightening of the entire industrial structure and structuring new convergent industrial bodies. To explore the degree of integration between the digital economy and the logistics industry, this paper uses input-output models and social network analysis to empirically analyse the level of industrial integration between the core industries of China's digital economy and the logistics industry during the period 2007–2017. The level of integration between the core industries of China's digital economy and the logistics industry is measured, and its spatial and temporal characteristics are also measured and analysed. The analysis showed that (1) the degree of integration between the two industries is low, but with changes over time, the degree of integration will follow an upwards trend; the overall level of integration is increasing with the development of the core industries of the digital economy; the growth rate is significant, and developed regions have a clear advantage because of the intensity of integration. (2) The direction of industrial integration linkages is basically stable, with the pointing characteristics of adjacent provinces, and the spatial distribution shows a pattern of diffusion from the central region to the eastern and western regions. Overall, the integration shows an economic radiation effect, but there are large differences between the north and south. (3) It is easier for adjacent provinces to form the same cohesive subgroup in a network and develop together. At the same time, the integration network shows a clear pattern of marginal-semimmarginalization. The study enriches and improves the research status of China's digital economy industry convergence, and provides theoretical support for the formulation of policies related to the synergistic development of China's digital economy and logistics industry. [ABSTRACT FROM AUTHOR]

Huangjiu is a national alcoholic beverage in China. Millet has congenital advantages in development and utilization of nutrient. Brewing Huangjiu with millet can increase the value of millet. Microbial community plays crucial roles in millet Huangjiu fermentation. Flavor compounds reflect the quality and health function of Huangjiu. The flavor compounds of Huangjiu are complex and their formation is closely associated with microorganisms, but the relationship between them during fermentation has been unknown. In this research, this relationship during millet Huangjiu fermentation were deeply investigated. Totally 86 volatile compounds were detected. Bacillus, Weissella, Paenibacillus, Klebsiella, Prevotella was investigated as the dominant microbes through high-throughput sequencing. 537 correlations between major flavor compounds and microbes were established to reflect the dynamic change during millet Huangjiu fermentation. The top five dominant genus of flavor producing microbes were Chryseobacterium, Sporolactobacillus, Psychrobacter, Sphingobium and Anoxybacillus. The content of malic acid and citric acid was gradually improved all through the millet Huangjiu fermentation. Malic acid and citric acid generated from millet Huangjiu fermentation shows healthy properties as liver protection and eliminating fatigue. Our research provides essential information on microbial community succession and the flavor formation during millet Huangjiu fermentation, and beneficial for development of Huangjiu products. [ABSTRACT FROM AUTHOR]

At present, the digital economy, which takes information technology and data as the key elements, is booming and has become an important force in promoting the economic growth of various countries. In order to explore the current dynamic trend of China's digital economy development and the impact of the digital economy on the high-quality economic development, this paper measures the digital economic development index of 30 cities in China from the three dimensions of digital infrastructure, digital industry, and digital integration, uses panel data of 30 cities in China from 2015 to 2019 to construct an econometric model for empirical analysis, and verifies the mediating effect of technological progress between the digital economy and high-quality economic development. The results show that (1) The development level of China's digital economy is increasing year by year, that the growth of digital infrastructure is obvious, and that the development of the digital industry is relatively slow. (2) Digital infrastructure, digital industry and digital integration all have significant positive effects on regional total factor productivity, and the influence coefficients are 0.2452, 0.0773 and 0.3458 respectively. (3) Regarding the transmission mechanism from the digital economy to the high-quality economic development, the study finds that the mediating effect of technological progress is 0.1527, of which the mediating effect of technological progress in the eastern, northeast, central and western regions is 1.70%, 9.25%, 28.89% and 21.22% respectively. (4) From the perspective of spatial distribution, the development level of the digital economy in the eastern region is much higher than that in other non-eastern regions, and the development of digital economy in the eastern region has a higher marginal contribution rate to the improvement of the total factor productivity. This study can provide a theoretical basis and practical support for the government to formulate policies for the development of the digital economy. [ABSTRACT FROM AUTHOR]

To analyze the post-COVID-19 construction and management of fever clinics targeted to prevention and control of healthcare-associated respiratory viral infections in medical institutions at all levels in China, and to provide a basis for promoting their standardized construction, we conducted this survey on the construction of fever clinics in 429 medical institutions of Jiangsu Province from July to December 2020. Contents of the questionnaire included the general situation of medical institutions, the construction status and future construction plans of fever clinics. We find the construction rate of fever clinic in medical institutions of Jiangsu province was 75.3%. All construction indicators, quality management systems and processes fail to fully meet the requirements of documents and standards. Jiangsu province actively promotes the construction of fever clinic layout, but there is still a gap with the construction standard. As a result, it is necessary to further promote standardized construction of fever clinic, and necessary financial input should be increased to expand all constructions of fever clinic in primary medical institutions., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Trichome is important for help plant resist adversity and external damage. However, it often affects the appearance and taste of vegetables. In the present study, the trichome density of leaves from two Chinese cabbage cultivars with and without trichomes treated at low temperature are analyzed by biological microscope, and the differentially expressed genes related to trichomes formation were screened through transcriptome sequencing. The results showed that the number of leaves trichomes was reduced by 34.7% at low temperature compared with room temperature. A total of 661 differentially expression genes effecting trichomes formation were identified at the CT vs C, LCT vs LC, CT vs LCT. Several differentially expression genes from every comparison group were enriched in plant hormone signal transduction and amino acid biosynthesis pathway. Combined with the central genes obtained by WGCNA analysis, five candidate genes Bra029778, Bra026393, Bra030270, Bra037264 and Bra009655 were screened. qRT-PCR analysis verified that the gene expression differences were in line with the trend of transcriptome data. This study not only found possible new key genes and laid a foundation for revealing the molecular mechanism regulating the formation of trichome in Chinese cabbage, but also provided a new way to study plant surface trichomes., Competing Interests: The authors have declared that no competing interests exist.

Vibrio parahaemolyticus is the leading cause of acute seafood-associated gastroenteritis worldwide. The aim of this study was to investigate the presence of virulence genes, biofilm formation, motor capacities and antimicrobial resistance profile of V. parahaemolyticus isolates isolated from clinical samples in Nantong during 2018-2020. Sixty-six V. parahaemolyticus strains isolated from stool specimens of diarrheal patients were examined. The PCR results showed that there were two tdh+trh+ isolates, four tdh-trh- isolates and sixty tdh+trh- isolates, accounting for 3.0%, 6.1% and 90.9%, respectively. All the tdh carrying isolates manifested the positive reactions for the Kanagawa phenomenon (KP) test. Most of the isolates harbored at least one of the specific DNA markers of 'pandemic group' strains, suggesting that the dominant isolates of V. parahaemolyticus in Nantong might belong to the new O3: K6 or its serovariants. All tdh+ isolates possessed the Vp-PAI genes, but no tdh-trh- isolates carried the T3SS2 genes. All isolates were biofilm producers and had relatively strong motor capacities. In addition, the V. parahaemolyticus isolates were resistant to ampicillin (98.5%), cefuroxime (75.6%), cefepime (66.7%), piperacillin (59.1%) and ampicillin/sulbactam (50.0%), but sensitive to ciprofloxacin (100.0%), levofloxacin (100.0%), trimethoprim-sulfamethoxazole (98.5%), gentamicin (98.5%), amikacin (97%), meropenem (71.2%), and ceftazidime (56.1%). Multidrug-resistant isolates in clinical might be related to the inappropriate use of antimicrobials in aquaculture., Competing Interests: The authors have declared that no competing interests exist.