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The article by Wells is a chance to ponder on the different conceptions of culture endorsed by the natural sciences and by the social sciences. The standard definition of culture among biologists/natural scientists usually focuses on transmission of behaviors (e.g. "tradition of socially learned behaviors"), while on the other hand anthropologists and social scientists focus more on the symbolic aspect of culture (e.g."webs of significance"). This differential emphasis likely reflects a difference in ontology (what culture is) and in its epistemology (how it can be studied). Natural scientists typically prefer to focus on how cultural traits change quantitatively, while social scientists are much more focused with the process of symbolic interpretation, which typically involves the ability to account for meaning and sense-making (thus, it is more qualitative-grounded). These two conceptions of culture are both valid but incomplete, if they do not take into account the counterpart. The scientific conundrum that has to be solved is how these two different onto-epistemologies can be successfully linked together. A speculative hypothesis is put forward. [ABSTRACT FROM AUTHOR]