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Effective prevention strategies for post-COVID complications are crucial for patients, clinicians, and policy makers to mitigate their cumulative burden. This study evaluated the association of modifiable lifestyle factors (smoking, alcohol intake, BMI, physical activity, sedentary time, sleep duration, and dietary habits) with COVID-19 multisystem sequelae, death, and hospitalization in the UK Biobank cohort (n = 68,896). A favorable lifestyle (6-10 healthy factors; 46.4%) was associated with a 36% lower risk of multisystem sequelae (HR, 0.64; 95% CI, 0.58-0.69; ARR at 210 days, 7.08%; 95% CI, 5.98-8.09) compared to an unfavorable lifestyle (0-4 factors; 12.3%). Risk reductions spanned all 10 organ systems, including cardiovascular, coagulation, metabolic, gastrointestinal, kidney, mental health, musculoskeletal, respiratory disorders, and fatigue. This beneficial effect was largely attributable to direct lifestyle impacts independent of corresponding pre-infection comorbidities (71% for any sequelae). A favorable lifestyle was also related to the risk of post-COVID death (HR 0.59, 0.52-0.66) and hospitalization (HR 0.78, 0.73-0.84). These associations persisted across acute and post-acute infection phases, irrespective of hospitalization status, vaccination, or SARS-CoV-2 variant. These findings underscore the clinical and public health importance of adhering to a healthy lifestyle in mitigating long-term COVID-19 adverse impacts and enhancing future pandemic preparedness. The impact of modifiable lifestyle factors on the risk of post-COVID-19 sequelae is not well understood. Here, the authors perform a prospective cohort study amongst UK Biobank participants and show that a healthy lifestyle is associated with lower risk of post-COVID-19 sequelae across multiple organ systems. [ABSTRACT FROM AUTHOR]

Road extraction from remote-sensing images is of great significance for vehicle navigation and emergency insurance. However, the road information extracted in the remote-sensing image is discontinuous because the road in the image is often obscured by the shadows of trees or buildings. Moreover, due to the scale difference of roads in remote-sensing images, it remains a computational challenge to extract small-size roads from remote-sensing images. To address those problems, we propose a road extraction method based on adaptive global feature fusion (AGF-Net). First, a dilated convolution strip attention (DCSA) module is designed from the encoder–decoder structure. It consists of the dilated convolution and the strip attention module, which adaptively emphasizes relevant features in vertical and horizontal directions. Then, multiple global feature fusion modules (GFFM) in the skip connection are designed to supplement the decoder with road detail features, and we design a multi-scale strip convolution module (MSCM) to implement the GFFM module to obtain multi-scale road information. We compare AGF-Net to state-of-the-art methods and report their performance using standard evaluation metrics, including Intersection over Union (IoU), F1-score, precision, and recall. Our proposed AGF-Net achieves higher accuracy compared to other existing methods on the Massachusetts Road Dataset, DeepGlobe Road Dataset, CHN6-CUG Road Dataset, and BJRoad Dataset. The IoU obtained on these datasets are 0.679, 0.673, 0.567, and 0.637, respectively. [ABSTRACT FROM AUTHOR]

RNA-binding proteins play crucial roles in the regulation of gene expression, and understanding the interactions between RNAs and RBPs in distinct cellular conditions forms the basis for comprehending the underlying RNA function. However, current computational methods pose challenges to the cross-prediction of RNA-protein binding events across diverse cell lines and tissue contexts. Here, we develop HDRNet, an end-to-end deep learning-based framework to precisely predict dynamic RBP binding events under diverse cellular conditions. Our results demonstrate that HDRNet can accurately and efficiently identify binding sites, particularly for dynamic prediction, outperforming other state-of-the-art models on 261 linear RNA datasets from both eCLIP and CLIP-seq, supplemented with additional tissue data. Moreover, we conduct motif and interpretation analyses to provide fresh insights into the pathological mechanisms underlying RNA-RBP interactions from various perspectives. Our functional genomic analysis further explores the gene-human disease associations, uncovering previously uncharacterized observations for a broad range of genetic disorders. Predicting dynamic RNA-RBP interactions in diverse cell lines is an important challenge in unravelling RNA function and post-transcriptional regulatory mechanisms. Here, authors develop HDRNet, an end-to-end deep-learning-based framework for accurately predicting dynamic RBP binding events across various cellular conditions. [ABSTRACT FROM AUTHOR]

To improve the ability of natural language processing (NLP) in mobile communication networks, a mobile communication network NLP system based on a recurrent neural network is designed in the eleventh paper, "A Novel Natural Language Processing Model in Mobile Communication Networks", authored by Gautam Srivastava from the Department of Mathematics and Computer Science, Brandon University, Canada. First of all, image and visual processing in mobile networks are the key technology in the research of information processing because 90% of human information got from world comes from vision [[1]]. Then, the varied applications of information processing under mobile network environment are other key topics in research because the application ecology determines the human acceptability of the digital world [[5]]. It is a kind of huge virtual digital world to people that the theories and applications of information processing have been changed to complex multimodal information processing. [Extracted from the article]

Deploying convolutional neural networks (CNNs) on mobile devices is difficult due to the limited memory and computation resources. We aim to design efficient neural networks for heterogeneous devices including CPU and GPU, by exploiting the redundancy in feature maps, which has rarely been investigated in neural architecture design. For CPU-like devices, we propose a novel CPU-efficient Ghost (C-Ghost) module to generate more feature maps from cheap operations. Based on a set of intrinsic feature maps, we apply a series of linear transformations with cheap cost to generate many ghost feature maps that could fully reveal information underlying intrinsic features. The proposed C-Ghost module can be taken as a plug-and-play component to upgrade existing convolutional neural networks. C-Ghost bottlenecks are designed to stack C-Ghost modules, and then the lightweight C-GhostNet can be easily established. We further consider the efficient networks for GPU devices. Without involving too many GPU-inefficient operations (e.g., depth-wise convolution) in a building stage, we propose to utilize the stage-wise feature redundancy to formulate GPU-efficient Ghost (G-Ghost) stage structure. The features in a stage are split into two parts where the first part is processed using the original block with fewer output channels for generating intrinsic features, and the other are generated using cheap operations by exploiting stage-wise redundancy. Experiments conducted on benchmarks demonstrate the effectiveness of the proposed C-Ghost module and the G-Ghost stage. C-GhostNet and G-GhostNet can achieve the optimal trade-off of accuracy and latency for CPU and GPU, respectively. MindSpore code is available at https://gitee.com/mindspore/models/pulls/1809, and PyTorch code is available at https://github.com/huawei-noah/CV-Backbones. [ABSTRACT FROM AUTHOR]