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Hypertension is one of the most important causes of cardiovascular disease. It has been found that professional drivers are at high risk of hypertension. This study has been performed to determine the prevalence of hypertension and its associated factors among professional drivers in Shahroud. In this study, the prevalence of hypertension was determined according to the definition by the American Heart Association among 1461 professional drivers participating in the first cross-sectional phase of Shahroud drivers' prospective cohort study. The prevalence of elevated blood pressure and hypertension was examined based on the initial age, and gender presented, along with the factors affecting this disease based on multinomial logistic regression. The prevalence of elevated blood pressure, stage 1 and 2 hypertension was 46.9%, 6%, and 1.3%, respectively. In the multivariate multinomial logistic regression model, having diabetes, Body Mass Index ≥25, and driving years was associated with an increased chance of developing elevated blood pressure and hypertension. Attention should be paid to high prevalence of elevated blood pressure and hypertension among professional drivers in Iran as a health priority for drivers. Plans should be made to reduce it as well as to prevent its complications. [ABSTRACT FROM AUTHOR]

Zircon U-Pb-Hf isotopes, integrated with bulk-rock major, trace element, and isotopic compositions of amphibolites from the Makran ophiolitic mélange complex (OMC), carry implications on the evolution of the Neo-Tethys Ocean. Field and petrographical-geochemical data confirm these amphibolites as products of the metamorphism of a mafic protolith. Zircons from the amphibolites have U-Pb ages of Late Early Permian (273 Ma) to Late Triassic (210 Ma), and their εHf(t) values vary from +6.32 to +15.4. The Makran amphibolites are geochemically similar to transitional- or enriched-MORBs. The 143Nd/144Nd(t) ratios for amphibolites range from 0.51260 to 0.512551, and 87Sr/86Sr(t) from 0.704433 to 0.706244. The Pb-isotope composition of these rocks is radiogenic, ranging from 15.61-15.64 for 207Pb/204Pb(t), 18.98-19.21 for 206Pb/204Pb(t) and 38.88-39.36 for 208Pb/204Pb(t). The isotopic and geochemical signatures of these rocks suggest that they were most likely formed during continental rifting and originated from a relatively enriched mantle source. This is also attested by their high zircon Ce/Ce* ratios. We interpret these amphibolites related to the Permian-Triassic plumes that triggered Gondwana rifting to open the Neo-Tethyan Ocean before metamorphosed, fragmented, and accreted into the Makran accretionary complex probably during Early to Late Cretaceous time. [ABSTRACT FROM AUTHOR]