8 results
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2. Hanging out at the club: Breeding status and territoriality affect individual space use, multi‐species overlap and pathogen transmission risk at a seabird colony
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Juliet Lamb, Jeremy Tornos, Romain Dedet, Hubert Gantelet, Nicolas Keck, Juliette Baron, Marine Bely, Augustin Clessin, Aline Flechet, Amandine Gamble, Thierry Boulinier, Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM), Laboratoire Départemental Vétérinaire de l'Hérault, Conseil Général de l'Hérault, CEVA- BIOVAC, University of California (UC), This work was funded by the French Polar Institute (IPEV ECOPATH-1151), ANR ECOPATHS (ANR-21-CE35-0016), Réserve Naturelle Nationale des Terres Australes Françaises, Zone Atelier Antarctique (ZATA) and OSU OREME ECOPOP. We also acknowledge funding support for REMOVE_DISEASE project selected as part of the BiodiveRestore joint call from Biodiversa and Water JPI (ANR-21-BIRE-0006). This paper is a contribution of the Plan National d'Action Albatros d'Amsterdam. Juliet Lamb was funded by a Marie Curie Individual Fellowship (H2020-MSCA-IF-2018 #843470), Amandine Gamble by a French Ministry of Research PhD fellowship, and Jeremy Tornos by Ceva Biovac and ANRT for a CIFRE PhD fellowship. Experimental design was approved by the Regional Animal Experimentation Ethical Committee (French Ministry of Research permit #10257-2018011712301381v6) and by the Comité de l'Environnement Polaire (A-2017-97, A-2017-111, A-2018-123, A 2018-139, A-2019-69, 2019-121, A-2019-132 and A-2019-135)., ANR-21-BIRE-0006,REMOVE_DISEASE,Conservation and restoration of degraded insular biodiversity: impacts of the removal of introduced mammals on the dynamics of infectious diseases in seabirds across islands of the Southern Ocean.(2021), and ANR-21-CE35-0016,ECOPATHS,Ecologie de la circulation des agents infectieux dans les populations de vertébrés coloniaux: surveillance, compréhension et implications pour la conservation de la biodiversité dans les îles sub-antarctiques(2021)
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[SDV.BA.ZV]Life Sciences [q-bio]/Animal biology/Vertebrate Zoology ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,Ecology, Evolution, Behavior and Systematics - Abstract
International audience; Wildlife movement ecology often focuses on breeders, whose territorial attachments facilitate trapping and following individuals over time. This leads to incomplete understanding of movements of individuals not actively breeding due to age, breeding failure, subordinance, and other factors. These individuals are often present in breeding populations and contribute to processes such as competition and pathogen spread. Therefore, excluding them from movement ecology studies could bias or mask important spatial dynamics. Loafing areas offer an alternative to breeding sites for capturing and tracking individuals. Such sites may allow for sampling individuals regardless of breeding status, while also avoiding disturbance of sensitive breeding areas. However, little is known about the breeding status of individuals attending loafing sites, or how their movements compare to those of breeders captured at nests. We captured a seabird, the brown skua, attending either nests or loafing areas (‘clubs’) at a multi-species seabird breeding site on Amsterdam Island (southern Indian Ocean). We outfitted skuas with GPS-UHF transmitters and inferred breeding statuses of individuals captured at clubs using movement patterns of breeders captured at nests. We then compared space use and activity patterns between breeders and nonbreeders. Both breeding and nonbreeding skuas attended clubs. Nonbreeders ranged more widely, were more active, and overlapped more with other seabirds and marine mammals than did breeders. Moreover, some nonbreeders occupied fixed territories and displayed more restricted movements than those without territories. Nonbreeders became less active over the breeding season, while activity of breeders remained stable. Nonbreeding skuas were exposed to the agent of avian cholera at similar rates to breeders but were more likely to forage in breeding areas of the endangered endemic Amsterdam albatross, increasing opportunities for interspecific pathogen transmission. Our results show that inference based only on breeders fails to capture important aspects of population-wide movement patterns. Capturing nonbreeders as well as breeders would help to improve population-level representation of movement patterns, elucidate and predict effects of external changes and conservation interventions (e.g. rat eradication) on movement patterns and pathogen spread, and develop strategies to manage outbreaks of diseases such as highly pathogenic avian influenza.; Les recherches sur l'écologie du déplacement de la faune sauvage au niveau individuel ciblent souvent des individus reproducteurs, car leur attachement territorial aux sites de reproduction facilite la capture, la recapture, et le suivi des individus à travers le temps. Au contraire, les individus qui ne reproduisent pas (à cause de leur âge, échec de reproduction, manque de dominance et autres facteurs) sont souvent exclus. Ces individus sont souvent présents aux sites de reproduction et contribuent aux processus de compétition, et de transmission des pathogènes. Par conséquence, leur exclusion des études de mouvements risque d'introduire des biais dans notre connaissance des dynamiques spatiales des populations. Les sites de repos présentent une alternative aux sites de reproduction pour la capture et suivi des individus. Ces sites présentent l'opportunité de capturer des oiseaux reproducteurs ainsi que non-reproducteurs, tout en évitant de déranger des sites sensibles de nidification. Néanmoins, les sites de repos sont peu connus, et il est difficile de déterminer si les oiseaux qui les utilisent sont reproducteurs ou non-reproducteurs, ou de savoir comment leurs mouvements se comparent à ceux d'oiseaux attrapés au nid. Nous avons capturé des oiseaux marins prédateurs, les labbes antarctiques, sur leurs nids ou sur des sites de repos partagés (« clubs »). Nous avons attaché des balises GPS-UHF aux oiseaux et avons déterminé le statut reproductif des oiseaux de statut inconnu en comparant leurs mouvements à ceux de labbes capturés au nid (et donc clairement reproducteurs). Nous avons ensuite comparé l'utilization de l'espace et les niveaux d'activité entre labbes reproducteurs et non-reproducteurs. Les labbes reproducteurs et non-reproducteurs étaient présents aux « clubs ». Comparés aux reproducteurs, les labbes non-reproducteurs utilisaient des surfaces plus grandes, étaient plus actifs, et exploitaient plus souvent des zones utilisées par d'autres espèces d'oiseaux et de mammifères marins. Par ailleurs, quelques labbes non-reproducteurs occupaient des territoires fixes et présentaient des mouvements plus limités que ceux qui n'occupaient pas de territoire. Les labbes non-reproducteurs étaient autant exposés à l'agent du choléra aviaire que les reproducteurs, mais ils se nourrissaient plus souvent dans l'habitat de l'albatros d'Amsterdam (une espèce en danger), augmentant leur probabilité de transmettre des pathogènes à cette espèce. Nos résultats montrent que les études de déplacement ne ciblant que les oiseaux reproducteurs ne représentent les déplacements de la population générale que de manière imparfaite. Capturer des oiseaux sur des sites de repos peut ainsi améliorer le taux de représentation. Le suivi des individus non-reproducteurs, de labbes ou d'autres espèces, peut aider à prédire les effets de changements des conditions externes (comme l'éradication des rats sur l'Amsterdam ou l'apparition et transmission de la grippe aviaire) qui peuvent altérer les dynamiques éco-épidemiologiques et les interactions entre espèces.
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- 2022
3. Statin Use and Incidence of Parkinson's Disease in Women from the French <scp>E3N</scp> Cohort Study
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Thi Thu Ha Nguyen, Agnès Fournier, Émeline Courtois, Fanny Artaud, Sylvie Escolano, Pascale Tubert‐Bitter, Marie‐Christine Boutron‐Ruault, Isabelle Degaey, Emmanuel Roze, Marianne Canonico, Ismaïl Ahmed, Anne C.M. Thiébaut, Alexis Elbaz, HAL UVSQ, Équipe, APPEL À PROJETS GÉNÉRIQUE 2018 - Facteurs de risque de la Maladie de Parkinson chez les femmes de la cohorte E3N - - PARKIN-WOMEN2018 - ANR-18-CE36-0006 - AAPG2018 - VALID, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), T.T.H.N. was supported by post‐doctoral grants from the Michael J Fox foundation and the France Parkinson association. E.C. was supported by post‐doctoral grants from the Michael J Fox foundation. F.A. reports no disclosures. S.E. reports no disclosures. P.T.‐B. reports no disclosures. M.‐C.B.‐R. received speaker fees in 2020 from MAYOLI‐SPINDLER and GILEAD outside the field of the present paper. I.D. reports no disclosures. E.R. received honorarium for speech from Orkyn Aguettant, Elivie and for participating in an advisory board from Allergan and has received research support from Merz‐Pharma, Orkyn, Aguettant, Elivie, Ipsen, Allergan, Everpharma, Fondation Desmarest, AMADYS, ADCY5.org , ANR, Societé Française de Médecine Esthétique, and Dystonia Medical Research Foundation. M.C. has obtained research grant from French National Research Agency (ANR). I.A. reports no disclosures. A.C.M.T. reports no disclosures. A.E. has obtained research grants from Plan Ecophyto (French ministry of agriculture) and France Parkinson., T.T.H.N. was supported by postdoctoral grants from The Michael J. Fox Foundation and the France Parkinson Association. E.C. was supported by postdoctoral grants from The Michael J. Fox foundation. F.A., S.E., P.T.‐B., I.A., and A.C.M.T. report no disclosures. M.‐C.B.‐R. received speaker fees in 2020 from Mayoli‐Spindler and Gilead outside the field of the present article. I.D. reports no disclosures. E.R. received honorarium for speeches from Orkyn Aguettant and Elivie and for participating in an advisory board from Allergan and has received research support from Merz‐Pharma, Orkyn, Aguettant, Elivie, Ipsen, Allergan, Everpharma, Fondation Desmarest, AMADYS, ADCY5.org , French National Research Agency (ANR), Societé Française de Médecine Esthétique, and the Dystonia Medical Research Foundation. M.C. obtained a research grant from the ANR. A.E. has obtained research grants from Plan Ecophyto (French Ministry of Agriculture) and France Parkinson Association. The work reported in this article was performed during A.F.'s term as a visiting scientist at the International Agency for Research on Cancer. The authors declare no other relationships or activities that could appear to have influenced the submitted work. Relevant conflicts of interest/financial disclosures, This work was realized with data of the E3N cohort (INSERM) and supported by the Mutuelle Générale de l'Education Nationale (MGEN), Gustave Roussy Institute, and French League against Cancer for the constitution and maintenance of the cohort. This work has benefited from State aid managed by the National Research Agency (ANR) under the program 'Investment in the future' bearing the reference ANR‐10‐COHO‐0006 and under the program 'Young researcher' bearing the reference ANR‐18‐CE36‐0006‐01, as well as a subsidy from the Ministry of Higher Education, Research and Innovation for public service charges bearing the reference N°2102918823, 2103236497, and 2103586016, and from IRESP (Institut de Recherche En Santé Publique). The authors acknowledge all women enrolled in the E3N cohort for their continued participation. They are also grateful to all members of the E3N study group., This project was funded by the Michael J. Fox Foundation for Parkinson's Research and the France Parkinson Association. Funding agencies., and ANR-18-CE36-0006,PARKIN-WOMEN,Facteurs de risque de la Maladie de Parkinson chez les femmes de la cohorte E3N(2018)
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[SDV] Life Sciences [q-bio] ,pharmacoepidemiology ,cohort studies ,drug repurposing ,Neurology ,Parkinson's disease ,[SDV]Life Sciences [q-bio] ,Neurology (clinical) ,statins - Abstract
International audience; Background: Statins represent candidates for drug repurposing in Parkinson's disease (PD). Few studies examined the role of reverse causation, statin subgroups, and dose–response relations based on time-varying exposures. Objectives: We examined whether statin use is associated with PD incidence while attempting to overcome the limitations described previously, especially reverse causation. Method: We used data from the E3N cohort study of French women (follow-up, 2004–2018). Incident PD was ascertained using multiple sources and validated by experts. New statin users were identified through linked drug claims. We set up a nested case-control study to describe trajectories of statin prescriptions and medical consultations before diagnosis. We used time-varying multivariable Cox proportional hazards regression models to examine the statins–PD association. Exposure indexes included ever use, cumulative duration/dose, and mean daily dose and were lagged by 5 years to address reverse causation. Results: The case-control study (693 cases, 13,784 controls) showed differences in case-control trajectories, with changes in the 5 years before diagnosis in cases. Of 73,925 women (aged 54–79 years), 524 developed PD and 11,552 started using statins in lagged analyses. Ever use of any statin was not associated with PD (hazard ratio [HR] = 0.87, 95% confidence interval [CI] = 0.67–1.11). Alternatively, ever use of lipophilic statins was significantly associated with lower PD incidence (HR = 0.70, 95% CI = 0.51–0.98), with a dose–response relation for the mean daily dose (P-linear trend = 0.02). There was no association for hydrophilic statins. Conclusion: Use of lipophilic statins at least 5 years earlier was associated with reduced PD incidence in women, with a dose–response relation for the mean daily dose. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society
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- 2023
4. Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
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Susan Thurstans, Stephanie V. Wrottesley, Bridget Fenn, Tanya Khara, Paluku Bahwere, James A. Berkley, Robert E. Black, Erin Boyd, Michel Garenne, Sheila Isanaka, Natasha Lelijveld, Christine M. McDonald, Andrew Mertens, Martha Mwangome, Kieran S. O'Brien, Heather Stobaugh, Sunita Taneja, Keith P. West, Saul Guerrero, Marko Kerac, André Briend, Mark Myatt, London School of Hygiene and Tropical Medicine (LSHTM), SOUtenabilité et RésilienCE (SOURCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Recherche pour le Développement (IRD [France-Nord]), Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Université Paris Cité (UPCité)-Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Paris Cité (UPCité)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Epicentre [Paris] [Médecins Sans Frontières], United States Agency for International Development, USAID, Irish Aid: HQPU/2021/ENN, This paper is made possible by the generous support of the American people through the United States Agency for International Development (USAID), and by funding from Irish Aid (grant number (HQPU/2021/ENN). The contents are entirely the responsibility of its authors and do not necessarily reflect the views of USAID or the United States Government or represent or reflect Irish Aid policy., Tampere University, and Clinical Medicine
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Male ,Adolescent ,wasting ,Thinness ,underweight ,3123 Gynaecology and paediatrics ,Clinical Research ,Prevalence ,Humans ,sex ,Child ,Growth Disorders ,Pediatric ,Nutrition and Dietetics ,Anthropometry ,Nutrition & Dietetics ,Wasting Syndrome ,Prevention ,Malnutrition ,stunting ,Public Health, Environmental and Occupational Health ,Infant ,Obstetrics and Gynecology ,mortality ,Good Health and Well Being ,age ,Pediatrics, Perinatology and Child Health ,Female ,Zero Hunger ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition - Abstract
Risk of death from undernutrition is thought to be higher in younger than in older children, but evidence is mixed. Research also demonstrates sex differences whereby boys have a higher prevalence of undernutrition than girls. This analysis described mortality risk associated with anthropometric deficits (wasting, underweight and stunting) in children 6–59 months by age and sex. We categorised children into younger (6–23 months) and older (24–59 months) age groups. Age and sex variations in near-term (within 6 months) mortality risk, associated with individual anthropometric deficits were assessed in a secondary analysis of multi-country cohort data. A random effects meta-analysis was performed. Data from seven low-or-middle-income-countries collected between 1977 and 2013 were analysed. One thousand twenty deaths were recorded for children with anthropometric deficits. Pooled meta-analysis estimates showed no differences by age in absolute mortality risk for wasting (RR 1.08, p = 0.826 for MUAC < 125 mm; RR 1.35, p = 0.272 for WHZ < −2). For underweight and stunting, absolute risk of death was higher in younger (RR 2.57, p < 0.001) compared with older children (RR 2.83, p < 0.001). For all deficits, there were no differences in mortality risk for girls compared with boys. There were no differences in the risk of mortality between younger and older wasted children, supporting continued inclusion of all children under-five in wasting treatment programmes. The risk of mortality associated with underweight and stunting was higher among younger children, suggesting that prevention programmes might be justified in focusing on younger children where resources are limited. There were no sex differences by age in mortality risk for all deficits.
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- 2022
5. The use of genetic tests to diagnose and manage patients with myeloproliferative and myeloproliferative/myelodysplastic neoplasms, and related disorders
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Catherine Cargo, Mamta Garg, Adam J. Mead, Anna L. Godfrey, Nicholas C.P. Cross, and Paper, A British Society for Haematology Good Practice
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medicine.medical_specialty ,Receptor, Platelet-Derived Growth Factor alpha ,Oncogene Proteins, Fusion ,Mutation, Missense ,Severity of Illness Index ,Receptors, Colony-Stimulating Factor ,Humans ,Point Mutation ,Medicine ,Eosinophilia ,Genetic Testing ,mRNA Cleavage and Polyadenylation Factors ,Biological Products ,Myeloproliferative Disorders ,business.industry ,Disease Management ,Bone Marrow Examination ,Exons ,Hematology ,Janus Kinase 2 ,Prognosis ,Dermatology ,Clone Cells ,Proto-Oncogene Proteins c-kit ,Molecular Diagnostic Techniques ,Myelodysplastic Syndromes ,medicine.symptom ,Calreticulin ,business ,Receptors, Thrombopoietin ,Forecasting - Published
- 2021
6. Combination of hydrophobicity and codon usage bias determines sorting of model K + channel protein to either mitochondria or endoplasmic reticulum.
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Engel AJ, Paech S, Langhans M, van Etten JL, Moroni A, Thiel G, and Rauh O
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- Animals, Mitochondria metabolism, Protein Transport, Endoplasmic Reticulum metabolism, Codon metabolism, Hydrophobic and Hydrophilic Interactions, Mammals genetics, Mammals metabolism, Codon Usage, Proteins metabolism
- Abstract
When the K
+ channel-like protein Kesv from Ectocarpus siliculosus virus 1 is heterologously expressed in mammalian cells, it is sorted to the mitochondria. This targeting can be redirected to the endoplasmic reticulum (ER) by altering the codon usage in distinct regions of the gene or by inserting a triplet of hydrophobic amino acids (AAs) into the protein's C-terminal transmembrane domain (ct-TMD). Systematic variations in the flavor of the inserted AAs and/or its codon usage show that a positive charge in the inserted AA triplet alone serves as strong signal for mitochondria sorting. In cases of neutral AA triplets, mitochondria sorting are favored by a combination of hydrophilic AAs and rarely used codons; sorting to the ER exhibits the inverse dependency. This propensity for ER sorting is particularly high when a common codon follows a rarer one in the AA triplet; mitochondria sorting in contrast is supported by codon uniformity. Since parameters like positive charge, hydrophobic AAs, and common codons are known to facilitate elongation of nascent proteins in the ribosome the data suggest a mechanism in which local changes in elongation velocity and co-translational folding in the ct-TMD influence intracellular protein sorting., (© 2023 The Authors. Traffic published by John Wiley & Sons Ltd.)- Published
- 2023
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7. Effects of feeding wood kraft pulp silage containing sweet-potato shochu distillery by-product on feed intake, feed digestibility, rumen fermentation, blood components, and growth performance in Japanese Black fattening steers during early period.
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Maeda Y, Nishimura K, Kurosu K, Mizuguchi H, Terada F, and Kushibiki S
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- Animals, Silage, Fermentation, Rumen metabolism, Digestion, Wood, Lipopolysaccharides metabolism, Diet veterinary, Eating, Aspartate Aminotransferases metabolism, Animal Feed analysis, Solanum tuberosum, Ipomoea batatas
- Abstract
The effects of long-term feeding of wood kraft pulp (KP) silage containing sweet-potato shochu distillery by-product (SDP) on feed intake, feed digestibility, rumen fermentation, and growth performance of Japanese Black steers were investigated during the early fattening period. Ten Japanese Black steers (9.8 ± 0.6 months of age) were used in this study. Five steers (KP group) were fed KP silage as a replacement for 10% timothy hay (dry matter bases), in contrast to the other five (control group). KP silage consisted of 92.9% KP and 7.1% SDP (dry matter bases). The experiment was conducted for 18 weeks. No significant differences were observed in terms of feed intake, feed digestibility, or daily body weight gain between the groups. In addition, diurnal changes in the rumen pH and ruminal lipopolysaccharide activity did not differ between the groups. However, the plasma concentration of aspartate transaminase in the KP group was slightly lower (P = 0.078) than that in the control group. Thus, our study suggested that feeding KP silage does not reduce feed intake or affect the rumen fermentation or growth performance of Japanese Black fattening steer., (© 2022 Japanese Society of Animal Science.)
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- 2022
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8. Effects of wood kraft pulp as a partial replacement for roughage on rumen fermentation and productivity in dairy cows.
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Yamamoto H, Shimizu Y, Hasunuma T, Manabe N, Osawa R, Kawashima K, Fukui Y, Ueno Y, Kurosu K, Mizuguchi H, Terada F, Sato S, Sugino T, and Kushibiki S
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- Animals, Cattle, Diet veterinary, Digestion, Fatty Acids, Volatile metabolism, Female, Fermentation, Lactation, Milk chemistry, Propionates metabolism, Wood, Dietary Fiber analysis, Rumen metabolism
- Abstract
In this study, we evaluated the partial replacement of roughage with wood kraft pulp (KP) on rumen fermentation and productivity of dairy cows. Eighteen cows were divided into control and KP groups. The KP group started adaptation to KP 3 weeks before calving; after calving, they were fed a total mixed ration for 12 weeks, wherein 18% Timothy hay was replaced with KP. The dry matter intake, body weight, and milk yield and composition were similar in the control and KP groups. The average daily rumen pH was higher with KP feeding, and the average daily ruminal temperature remained lower at 16 days after calving (P < 0.05). The concentration of volatile fatty acids remained unaltered, the molar proportion of acetic acid decreased, and the molar proportion of propionic acid increased, indicating a low acetic acid:propionic acid ratio (P < 0.05). Lipopolysaccharide activity in the rumen fluid was higher in the KP group (P < 0.05); however, the rumen microbiota were unaffected. The digestibility of dry matter and neutral detergent fiber increased 12 weeks after calving, whereas excretion of urinary nitrogen decreased (P < 0.05). Partial replacement of roughage with KP did not suppress rumen fermentation and maintained postpartum productivity., (© 2022 Japanese Society of Animal Science.)
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- 2022
- Full Text
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