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Your search keyword '"Hoque, Md. Emdadul"' showing total 2 results
Start Over Author "Hoque, Md. Emdadul" Topic carboxylic acids Publication Year Range Last 3 years Publisher wiley-blackwell
2 results on '"Hoque, Md. Emdadul"'

1. Ligand‐Enabled Double γ‐C(sp3)−H Functionalization of Aliphatic Acids: One‐Step Synthesis of γ‐Arylated γ‐Lactones.

Author

Hoque, Md. Emdadul and Yu, Jin‐Quan

Subjects
*CARBOXYLIC acids, *ACIDS, *LACTONES
Abstract

γ‐methylene C(sp3)−H functionalization of linear free carboxylic acids remains a significant challenge. Here in we report a Pd(II)‐catalyzed tandem γ‐arylation and γ‐lactonization of aliphatic acids enabled by a L,X‐type CarboxPyridone ligand. A wide range of γ‐arylated γ‐lactones are synthesized in a single step from aliphatic acids in moderate to good yield. Arylated lactones can readily be converted into disubstituted tetrahydrofurans, a prominent scaffold amongst bioactive molecules. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
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2. Ligand‐Enabled Double γ‐C(sp3)−H Functionalization of Aliphatic Acids: One‐Step Synthesis of γ‐Arylated γ‐Lactones.

Author

Hoque, Md. Emdadul and Yu, Jin‐Quan

Subjects
*CARBOXYLIC acids, *ACIDS, *LACTONES
Abstract

γ‐methylene C(sp3)−H functionalization of linear free carboxylic acids remains a significant challenge. Here in we report a Pd(II)‐catalyzed tandem γ‐arylation and γ‐lactonization of aliphatic acids enabled by a L,X‐type CarboxPyridone ligand. A wide range of γ‐arylated γ‐lactones are synthesized in a single step from aliphatic acids in moderate to good yield. Arylated lactones can readily be converted into disubstituted tetrahydrofurans, a prominent scaffold amongst bioactive molecules. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

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