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This paper analyzes the media agendas on the vaccination process against Covid-19 in the main digital media in Argentina and the consumption of these news on Facebook, the main world´s social network. From a content analysis on the most relevant news in digital media on the subject and on those with the highest level of engagement, it was intended to determine: 1) the thematic composition of both agendas; 2) the differential presence of actors and points of view in the news; 3) the predominant affective attributes in the media treatment and in the public agenda; and 4) the frames that shaped the information in each of the platforms. The results show the existence of news gaps in terms of topics and frames, in a context of a heavily concentrated media environment. [ABSTRACT FROM AUTHOR]